Coronary artery disease Clinical Trials in Charleston, SC
As of October 2026, 3 paid clinical trials are recruiting for Coronary artery disease in Charleston, South Carolina. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Related specialties in Charleston
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3 clinical trials for Coronary artery disease
·Clear filters·Prospective Registry of Patients Undergoing Cardiac CT With NAEOTOM Alpha PCD-CT Before TAVI Procedure
Product Surveillance Registry
Top Research Study Locations in Charleston
Researchers run research studies in Charleston, SC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Medical University of South Carolina | Heart Failure, Parkinson Disease, Smoking Cessation | 374 |
| Medical University of South Carolina (MUSC) | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 25 |
| Ralph H. Johnson VA Medical Center, Charleston, SC | Stroke, Depression, PTSD | 22 |
| Ralph H Johnson VA Medical Center | Stage IV Lung Cancer AJCC v8, Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum | 11 |
| MUSC | Heart Failure, Cardiovascular Diseases, Focal Epilepsy | 7 |
| MUSC Hollings Cancer Center | Advanced Renal Cell Carcinoma (RCC), Advanced Solid Tumor, Cachexia | 7 |
| Medical University of South Carolina Hollings Cancer Center | Brain Metastases, Cancer (With CNS Involvement), Locally Advanced Pancreatic Adenocarcinoma | 7 |
| Medical University of South Carolina University Hospital | Ischemic Stroke, Intracerebral Hemorrhage, Atrial Fibrillation | 5 |
| Ralph H. Johnson VA Health Care System | Adjustment Disorders, Alzheimer Disease, Alzheimer's Disease (AD) | 5 |
| Hollings Cancer Center at Medical University of South Carolina | B-cell Non Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, Locally Advanced Pancreatic Adenocarcinoma | 4 |
| Charleston Neuroscience Institute | NAION( Non-arteritic Anterior Ischemic Optic Neuropathy), Neovascular Age-related Macular Degeneration, Open Angle Glaucoma (OAG) | 4 |
| GSK Investigational Site | Asthma, Chickenpox, Neoplasms, Head and Neck | 3 |
| Bon Secours Saint Francis Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, HER2-Negative Breast Carcinoma | 3 |
| Clinical Trial Site | High Cardiovascular Risk, High Risk Cardiovascular Disease, Hypertension | 3 |
| Hollings Cancer Center | Acute Myeloid Leukemia, Breast Cancer, Chronic Myelomonocytic Leukemia | 3 |
| Lowcountry Lung and Critical Care, PA | Idiopathic Hypersomnia, Idiopathic Pulmonary Fibrosis (IPF), OSA | 3 |
| MUSC Charleston | Arteriovenous Fistula, Catheter Complications, Catheter Dysfunction | 3 |
| Medical University South Carolina | Knee Arthroplasty, Total, Lower Respiratory Tract Infection, Myasthenia Gravis | 3 |
| Medical University of South Carolina - South Carolina Translational Research Nexus Clinic | Atopic Dermatitis, Eczema, Severe Alopecia Areata | 3 |
| Medical University of South Carolina Children's Hospital | Focal Segmental Glomerulosclerosis, Rheumatic Joint Disease | 3 |
| Ralph H. Johnson VA Medical Center | Alzheimers Disease, Fatigue, Prostate Cancer | 3 |
| University of South Carolina | Alpha1-Antitrypsin Deficiency, Growth Hormone Deficiency, Lupus Nephritis | 3 |
| 30 Bee Street | Depression, Post Stroke Pain | 2 |
| 89bio Clinical Study Site | Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis | 2 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, MASH With Fibrosis, NASH - Nonalcoholic Steatohepatitis | 2 |
Active & Upcoming Studies in Charleston (2026)
Recruiting trials in Charleston grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (156 active studies)
- A Phase II Study of Biomarker-Guided De-escalation Using Anthracycline-Free Neoadjuvant Chemoimmunotherapy in Early-Stage Triple Negative Breast Cancer (TNBC) Patients With High Tumor-Infiltrating Lymphocytes (TILs) · Phase 2 · Medical University of South Carolina
- Study of Autologous, Metabolically Optimized, CD137+ Tumor-Infiltrating Lymphocytes Followed by Consolidative Oral Cyclophosphamide, Bevacizumab, and Pembrolizumab · Phase 2 · Medical University of South Carolina
Cardiovascular (58 active studies)
Mental health & behavior (56 active studies)
- PTSD and Alcohol Couples Treatment for Veterans · EARLY_Phase 1 · VA Office of Research and Development
- CHW-Enhanced Trauma Recovery · Medical University of South Carolina
Neurology & pain (56 active studies)
- Prescriptive Infusion Algorithm (PIA) · Phase 2 · AskBio Inc
- Cilostazol for Prevention of Recurrent Stroke Trial · Phase 3 · Stanford University
Diabetes & metabolic (16 active studies)
- Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients · Phase 1 · Medical University of South Carolina
- Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS) · Phase 3 · Eli Lilly and Company
Eye & vision (12 active studies)
- A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-005) · Phase 3 · Merck Sharp & Dohme LLC
- A Study to Evaluate the Efficacy and Safety of Tabirafusp Tedromer Compared to Aflibercept in Participants With DME - ALTO · Phase 3 · Kodiak Sciences Inc
Pediatric (11 active studies)
- The CATSINDO Trial - Clinical and Translational Study in Newly Diagnosed Osteosarcoma · Phase 2 · Wake Forest University Health Sciences
- A Pragmatic Clinical Trial of the WE BEAT Well-Being Education Program in Adolescent Congenital Heart Disease: WE BEAT CHD Study · Carelon Research
Vaccines (4 active studies)
- A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Given to Healthy Children 4 to 6 Years of Age · Phase 3 · GlaxoSmithKline
- A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised · Phase 3 · Pfizer
HIV / STI (3 active studies)
- Engaging Pharmacists to Advance Tobacco Treatment Service Delivery · Medical University of South Carolina
- Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People · Medical University of South Carolina
Common conditions studied in Charleston
- Heart Failure (14 active studies)
- Stroke (14 active studies)
- Depression (12 active studies)
- Cardiovascular Diseases (9 active studies)
- Obesity (9 active studies)
- Acute Myeloid Leukemia (7 active studies)
Leading research sponsors in Charleston
- Medical University of South Carolina
- VA Office of Research and Development
- National Cancer Institute (NCI)
- AstraZeneca
- Children's Oncology Group
Frequently asked questions
How many paid clinical trials are currently recruiting in Charleston?
There are approximately 678 recruiting clinical trials in Charleston, South Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Charleston pay participants?
Most recruiting trials in Charleston compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Charleston?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Charleston?
The most common conditions under active study in Charleston include Heart Failure (14), Stroke (14), Depression (12), Cardiovascular Diseases (9), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Charleston?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Charleston on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Charleston?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Charleston?
Recruiting research sites in Charleston include Medical University of South Carolina, Medical University of South Carolina (MUSC), Ralph H. Johnson VA Medical Center, Charleston, SC, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Charleston right now?
The largest active categories in Charleston are Cancer & tumors (156), Cardiovascular (58), Mental health & behavior (56). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.