Paid Clinical Trials in Clearwater, FL
As of June 2026, 120 paid clinical trials are recruiting in Clearwater, Florida. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Clearwater offers studies at sites including Morton Plant Hospital for conditions such as Heart Failure, Systemic Lupus Erythematosus, Breast Cancer, Coronary Artery Disease. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Clearwater
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·Clear filters·↓ Download CSVAbout research studies in Clearwater
Clearwater has approximately 120 recruiting research studies across a wide range of therapeutic areas. Florida hosts major research centers including Mayo Clinic Jacksonville, Moffitt Cancer Center, University of Miami Health System, and Nicklaus Children's Hospital, with strong programs in oncology and cardiovascular research.
Top Research Study Locations in Clearwater
Researchers run research studies in Clearwater, FL at 50 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Morton Plant Hospital | Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer, Anatomic Stage I Breast Cancer AJCC v8 | 17 |
| Clearwater Cardiovascular Consultants | Acute Myocardial Infarction, Arterial Disease of Legs, Below-the-knee Obstruction | 6 |
| Clinical Research of West Florida, Inc. | Cardiovascular Diseases, Diabetes Mellitus, Type 2, Gout | 4 |
| BayCare Health System | Atrial Fibrillation (AF), Coronary Artery Disease, Heart Failure | 3 |
| Clearwater Cardiovascular and Interventional Consultants | Cardiovascular Diseases, Coronary Artery Disease, Heart Failure | 3 |
| Gastro Florida | C. Diff Infection, C.Difficile Diarrhea, CDI | 3 |
| Innovative Research of West Florida, Inc. | COPD, Influenza, Refractory or Unexplained Chronic Cough | 3 |
| St. Francis Medical Institute | Bronchiectasis, Idiopathic Pulmonary Fibrosis, OSA | 3 |
| Clinical Research Of West Florida - Phase I Unit | Rheumatoid Arthritis, Psoriatic Arthritis, Polymyalgia Rheumatica | 3 |
| BayCare Health | Aortic Insufficiency, Aortic Regurgitation, Aortic Valve Insufficiency | 2 |
| BayCare Health Systems | Atrial Fibrillation, Diabetes Mellitus, Type 1 | 2 |
| Clinical Res Of W Florida | Diffuse Cutaneous Systemic Sclerosis, Systemic Lupus Erythematosus | 2 |
| Clinical Research of West Florida - Clearwater | COPD, Osteoarthritis, Knee | 2 |
| Clinical Research of West Florida, Inc | Rheumatoid Arthritis, Systemic Lupus Erythematosus | 2 |
| Florida Cancer Specialists | Advanced Non-Small Cell Lung Cancer, Breast Cancer, Breast Neoplasms | 2 |
| Florida Fertility Institute | In Vitro Maturation of Oocytes, Infertility, Female, Polycystic Ovary Syndrome | 2 |
| Tampa Bay Medical Research | Diabetes Mellitus, Type 2, Liver Fibrosis, Metabolic Dysfunction Associated Steatohepatitis (MASH) | 2 |
| Advanced Surgical Care of Clearwater | Lumbar Spinal Stenosis | 1 |
| American Arthritis and Rheumatology Associates LLC | Rheumatoid Arthritis | 1 |
| Anthos Investigative | Atrial Fibrillation (AF) | 1 |
| Anthos Investigative | Atrial Fibrillation (AF) | 1 |
| BayCare Medical Group | Percutaneous Coronary Intervention, Peripheral Endovascular Intervention | 1 |
| BayCare Medical Group Cardiology | Paroxysmal Atrial Fibrillation | 1 |
| BayCare Medical Group, Morton Plant | Fluid Overload, Heart Failure, Heart Failure (for Example, Fluid Overload) | 1 |
| Belleair Surgery Center Ltd | Lumbar Spinal Stenosis | 1 |
| CAN Community Health | HIV, HIV (Human Immunodeficiency Virus), HIV -1 Infection | 1 |
| CHF Heart Clinical (Subject Visits & IP Shipments) | Heart Failure, Heart Failure With Reduced Ejection Fraction | 1 |
| Catalyst Physical Therapy | Radiculopathy Lumbar, Radiculopathy Multiple Sites, Radiculopathy Sacral | 1 |
| Cheek-Powell Heart and Vascular Pavilion | Cardiovascular Diseases, Coronary Artery Disease, In-Stent Restenosis | 1 |
| Clinical Research of West Florida | Arthritis, Psoriatic | 1 |
| Clinical Research of West Florida - Corporate | Systemic Lupus Erythematosus (SLE) | 1 |
| Clinical Research of West Florida 1 | Lupus Erythematosus, Systemic | 1 |
| Clinical Research of West Florida Inc | Chronic Obstructive Pulmonary Disease | 1 |
| Clinical Research of West Florida Inc - Clearwater | Sjögren's Syndrome | 1 |
| Clinical Research of West Florida | Clearwater, FL | Psoriatic Arthritis | 1 |
| Clinical Research of West Florida, Inc. (Clearwater) | Rheumatoid Arthritis (RA) | 1 |
| Clinical Trial Site | Generalized Myasthenia Gravis | 1 |
| EncompaSSc site in Clearwater, FL 33765 | Diffuse Cutaneous Systemic Sclerosis | 1 |
| Florida Cancer Specialists North / Sarah Cannon Research Institute | Advanced Solid Tumors, Lymphoma, Non-Hodgkin, Multiple Myeloma | 1 |
| GSK Investigational Site | Systemic Lupus Erythematosus | 1 |
| Gastroenterology Consultants of Clearwater | Crohn's Disease | 1 |
| High Point Neighborhood Family Center | Advance Care Planning, Advance Directives, Chronic Illness | 1 |
| Innovative Research of West Florida | COVID-19 SARS-CoV-2 Infection | 1 |
| Innovative Research of West Florida | Hypothyroidism | 1 |
| Investigative Site | CLE, Cutaneous Lupus Erythematosus (CLE), SLE | 1 |
| Local Institution - 0021 | Plaque Psoriasis | 1 |
| Local Institution - 0694 | Carcinoma, Non-Small-Cell Lung | 1 |
| Mease Countryside Hospital | Coronary Artery Disease | 1 |
| Morton Plant | Mitral Valve Regurgitation | 1 |
| Morton Plant Hospital - Bay Care | Triple Negative Breast Cancer | 1 |
Active & Upcoming Studies in Clearwater (2026)
Recruiting trials in Clearwater grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cardiovascular (23 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- BoxX-NoAF Clinical Trial · AtriCure, Inc.
Cancer & tumors (22 active studies)
- Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer · Phase 3 · Pfizer
- ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab · Phase 3 · Alliance for Clinical Trials in Oncology
Diabetes & metabolic (6 active studies)
- A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight · Phase 3 · Novo Nordisk A/S
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
Vaccines (2 active studies)
- A Study to Evaluate the Safety and Efficacy of CD388 for Prevention of Influenza · Phase 3 · Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
- A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease · Phase 3 · Pfizer
HIV / STI (1 active study)
- REINItiation of Antiretroviral Therapy Using Oral bicTegravir, emtrIcitAbine and Tenofovir alafenamidE · Phase 4 · CAN Community Health
Neurology & pain (1 active study)
Common conditions studied in Clearwater
- Heart Failure (6 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Systemic Lupus Erythematosus (6 active studies). Lupus trials explore B-cell and interferon-targeted therapies, CAR-T approaches, and new immunosuppressants for systemic disease.
- Breast Cancer (5 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Coronary Artery Disease (5 active studies). Coronary artery disease research evaluates lipid-lowering therapies, anti-inflammatory agents, and new revascularization devices.
- Anatomic Stage II Breast Cancer AJCC v8 (4 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Anatomic Stage I Breast Cancer AJCC v8 (3 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
Leading research sponsors in Clearwater
- AstraZeneca
- Boehringer Ingelheim
- AbbVie
- Alliance for Clinical Trials in Oncology
- Concept Medical Inc.
Local regulations and guidelines
Clinical trials in Florida are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Florida research must also comply with the Florida Information Protection Act (FIPA) and additional oversight from the Florida Department of Health.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Clearwater. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Clearwater
Hipa.ai aggregates every recruiting study in Clearwater from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Clearwater?
There are approximately 120 recruiting clinical trials in Clearwater, Florida listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Clearwater pay participants?
Most recruiting trials in Clearwater compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Clearwater?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Clearwater?
The most common conditions under active study in Clearwater include Heart Failure (6), Systemic Lupus Erythematosus (6), Breast Cancer (5), Coronary Artery Disease (5), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Clearwater?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Clearwater on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Clearwater?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Clearwater?
Recruiting research sites in Clearwater include Morton Plant Hospital, Clearwater Cardiovascular Consultants, Clinical Research of West Florida, Inc., among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Clearwater right now?
The largest active categories in Clearwater are Cardiovascular (23), Cancer & tumors (22), Diabetes & metabolic (6). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.