Rethinking Early Airway Clearence Therapies
for Cystic Fibrosis (CF)
Sites in Dayton, Cincinnati +34 more locations
Sponsor: Nicole Hamblett
Sex: All·Age: 3 - 16
Code: NCT07696338·Not Yet Recruiting·Listed Jul 10, 2026
Clinical Trials at Dayton Children's Hospital
As of September 2026, 30 paid clinical trials are recruiting at Dayton Children's Hospital, located at 1 CHILDRENS PLZ, DAYTON, OH 45404-1815, phone (937) 641-3000 in Dayton, Ohio. Active studies at this site cover conditions such as Obesity, Stage IV Lung Cancer AJCC v8 and Anatomic Stage II Breast Cancer AJCC v8. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Dayton
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
31 clinical trials at Dayton Children's Hospital
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Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
for Childhood Extracranial Germ Cell Tumor
Sites in Dayton, Wilmington +380 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: All ages
Code: NCT03067181·Phase 3·Recruiting·Listed Mar 2017
A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab
for Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8
Drug: Nivolumab
Sites in Dayton, Cincinnati +378 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 5 - 60
Code: NCT05675410·Phase 3·Recruiting·Listed Jan 2023
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer
for Hematopoietic and Lymphatic System Neoplasm
Sites in Dayton, Columbus +189 more locations
Sponsor: Children's Oncology Group
Sex: Female·Age: Up to 39
Code: NCT06513962·Phase 3·Recruiting·Listed Jul 2024
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
for B Acute Lymphoblastic Leukemia
Sites in Dayton, Cincinnati +185 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: 365 Days - 25
Code: NCT03959085·Phase 3·Recruiting·Listed May 2019
A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)
for B Acute Lymphoblastic Leukemia
Sites in Dayton, Cincinnati +136 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 366 Days - 46
Code: NCT06124157·Phase 2·Recruiting·Listed Nov 2023
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations
for Acute Myeloid Leukemia
Sites in Dayton, Cincinnati +167 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: Up to 21
Code: NCT04293562·Phase 3·Recruiting·Listed Mar 2020
Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia
for Acute Leukemia of Ambiguous Lineage
Drug: Venetoclax
Sites in Dayton, Cincinnati +110 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: Up to 365 Days
Code: NCT06317662·Phase 2·Recruiting·Listed Mar 2024
A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis
for Recurrent Langerhans Cell Histiocytosis
Sites in Dayton, Columbus +99 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 180 Days - 22
Code: NCT05828069·Phase 2·Recruiting·Listed Apr 2023
Project: Every Child for Younger Patients With Cancer
for Adrenal Gland Pheochromocytoma
Sites in Dayton, Cincinnati +225 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: Up to 25
Code: NCT02402244·Recruiting·Listed Mar 2015
A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)
for Stage I Mixed Cell Type Kidney Wilms Tumor
Sites in Dayton, Cincinnati +151 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: Up to 30
Code: NCT06401330·Phase 3·Recruiting·Listed May 2024
A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT
for Anaplastic Kidney Wilms Tumor
Sites in Dayton, Cincinnati +170 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: Up to 30
Code: NCT04322318·Phase 2·Recruiting·Listed Mar 2020
A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)
for Malignant Glioma
Drug: Selinexor
Sites in Dayton, Cincinnati +104 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 12 Months - 21
Code: NCT05099003·Phase 1, Phase 2·Recruiting·Listed Oct 2021
A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma
for Low Grade Astrocytoma
Drug: Selumetinib
Sites in Dayton, Cincinnati +115 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 2 - 21
Code: NCT04166409·Phase 3·Recruiting·Listed Nov 2019
A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)
for Stage II Nasopharyngeal Carcinoma AJCC v8
Drug: Nivolumab
Sites in Dayton, Cincinnati +73 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: Up to 21
Code: NCT06064097·Phase 2·Recruiting·Listed Oct 2023
The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study
for Acute Lymphoblastic Leukemia
Sites in Dayton, Cincinnati +154 more locations
Sponsor: PedAL BCU, LLC
Sex: All·Age: Up to 22
Code: NCT04726241·Phase 1, Phase 2·Recruiting·Listed Jan 2021
Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma
for Metastatic Malignant Neoplasm in the Lung
Sites in Dayton, Cincinnati +200 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: Up to 50
Code: NCT05235165·Phase 3·Recruiting·Listed Feb 2022
Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma
for Ganglioneuroblastoma, Nodular
Sites in Dayton, Cincinnati +152 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: Up to 30
Code: NCT06172296·Phase 3·Recruiting·Listed Dec 2023
Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)
for Ganglioneuroblastoma
Sites in Dayton, Cincinnati +141 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: 365 Days - 30
Code: NCT03126916·Phase 3·Recruiting·Listed Apr 2017
A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT
for Central Nervous System Nongerminomatous Germ Cell Tumor
Sites in Dayton, Cincinnati +139 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: 3 - 29
Code: NCT04684368·Phase 2·Recruiting·Listed Dec 2020
A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia
for B Acute Lymphoblastic Leukemia Associated With Down Syndrome
Sites in Dayton, Columbus +70 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: 6 - 39
Code: NCT05702645·Recruiting·Listed Jan 2023
A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss
for Childhood Medulloblastoma
Sites in Dayton, Cincinnati +100 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: 4 - 21
Code: NCT05382338·Phase 3·Recruiting·Listed May 2022
Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma
for Pleuropulmonary Blastoma
Sites in Dayton, Cincinnati +78 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: Up to 21
Code: NCT06647953·Phase 3·Recruiting·Listed Oct 2024
Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma
for Embryonal Rhabdomyosarcoma
Sites in Dayton, Cincinnati +162 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: Up to 21
Code: NCT05304585·Phase 3·Recruiting·Listed Mar 2022
Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study
for Cystic Fibrosis
Sites in Dayton, Cincinnati +57 more locations
Sponsor: Chris Goss
Sex: All·Age: 6+
Code: NCT05548283·Phase 4·Recruiting·Listed Sep 2022
A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)
for Down Syndrome
Drug: Nivolumab
Sites in Dayton, Cincinnati +148 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 1 - 30
Code: NCT04546399·Phase 2·Recruiting·Listed Sep 2020
Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)
for Cardiac Arrest, Out-Of-Hospital
Sites in Dayton, Cincinnati +45 more locations
Sponsor: University of Michigan
Sex: All·Age: 2 Days - 17
Code: NCT05376267·Recruiting·Listed May 2022
I-DECIDE After Bronchiolitis Hospitalization
for Bronchiolitis Acute
Sites in Dayton, Cincinnati +54 more locations
Sponsor: Seattle Children's Hospital
Sex: All·Age: 0 Months - 24 Months
Code: NCT07243652·Recruiting·Listed Nov 2025
A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators
for Cystic Fibrosis
Sites in Dayton, Cincinnati +66 more locations
Sponsor: Nicole Hamblett
Sex: All·Age: 12+
Code: NCT06504589·Recruiting·Listed Jul 2024
The Pediatric Anesthesia Quality Improvement Project
for Surgery
Sites in Dayton, Cincinnati +35 more locations
Sponsor: The Society for Pediatric Anesthesia
Sex: All·Age: Up to 21
Code: NCT00674388·Recruiting·Listed May 2008
Dopamine vs. Norepinephrine for Hypotension in Very Preterm Infants With Late-onset Sepsis
for Late-Onset Neonatal Sepsis
Sites in Dayton +2 more locations
Sponsor: Mount Sinai Hospital, Canada
Sex: All·Age: 21 Weeks - 32 Weeks
Code: NCT05347238·Recruiting·Listed Apr 2022
Common conditions studied in Dayton
- Obesity (5 active studies)
- Stage IV Lung Cancer AJCC v8 (5 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (4 active studies)
- Malignant Solid Neoplasm (4 active studies)
- Overweight (4 active studies)
- Stage IIIB Lung Cancer AJCC v8 (4 active studies)
Leading research sponsors in Dayton
- National Cancer Institute (NCI)
- Children's Oncology Group
- SWOG Cancer Research Network
- Alliance for Clinical Trials in Oncology
- Eli Lilly and Company
Frequently asked questions
How many paid clinical trials are currently recruiting in Dayton?
There are approximately 181 recruiting clinical trials in Dayton, Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Dayton pay participants?
Most recruiting trials in Dayton compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Dayton?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Dayton?
The most common conditions under active study in Dayton include Obesity (5), Stage IV Lung Cancer AJCC v8 (5), Anatomic Stage II Breast Cancer AJCC v8 (4), Malignant Solid Neoplasm (4), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Dayton?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Dayton on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Dayton?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Dayton?
Recruiting research sites in Dayton include Miami Valley Hospital North, Miami Valley Hospital, Premier Blood and Cancer Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Dayton right now?
The largest active categories in Dayton are Cancer & tumors (77), Neurology & pain (15), Diabetes & metabolic (12). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of Dayton Children's Hospital?
Dayton Children's Hospital is located at 1 CHILDRENS PLZ, DAYTON, OH 45404-1815. Use the Google Maps link in the intro above to get directions.
How do I contact Dayton Children's Hospital?
You can reach Dayton Children's Hospital by phone at (937) 641-3000. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.
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