Oncology Clinical Trials in Fort Worth, TX
As of July 2026, 80 paid clinical trials are recruiting for Oncology in Fort Worth, Texas. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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80 clinical trials for Oncology
·Clear filters·↓ Download CSVA Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.
TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
A Study to Customize Ibrutinib Treatment Regimens for Participants With Previously Untreated Chronic Lymphocytic Leukemia
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy
A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)
Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion
A Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy (GOLSEEK-4)
A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.
A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer
A Study of PHST001 in Advanced Solid Tumors
A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors
A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)
A Study of TRK-950 When Used in Combination With Ramucirumab and Paclitaxel in Patients With Gastric Cancer
A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions
A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types
A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer
Study of Navtemadlin as Maintenance Therapy in TP53WT Advanced or Recurrent Endometrial Cancer
Study of INCB123667 in Subjects With Advanced Solid Tumors
A Phase 1 Study of BMS-986500 as Monotherapy or Combination Therapy in Advanced Solid Tumors
About research studies in Fort Worth
Fort Worth has approximately 342 recruiting research studies across a wide range of therapeutic areas. Texas hosts major cancer and cardiovascular research centers including MD Anderson Cancer Center, Baylor College of Medicine, UT Southwestern Medical Center, and the Texas Medical Center — the largest medical complex in the world.
Top Research Study Locations in Fort Worth
Researchers run research studies in Fort Worth, TX at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Cook Children's Medical Center | B Acute Lymphoblastic Leukemia, Cystic Fibrosis, Dravet Syndrome | 59 |
| UT Southwestern/Simmons Cancer Center-Fort Worth | Stage IVB Prostate Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8 | 28 |
| Cook Children's Health Care System | Langerhans Cell Histiocytosis, Anesthesia, Catheter-Related Infections | 11 |
| Re:Cognition Health - Fort Worth | Alzheimers Disease, Chronic Pain, Osteoarthritis, Knee | 8 |
| Cook Children's Hospital | Duchenne Muscular Dystrophy, Hodgkin Lymphoma, ALL | 7 |
| JPS Health Network | Asthma, Asthma Attack, Asthma Exacerbations | 6 |
| Texas Christian University | Criminal Behavior, Dementia, Drug Overdose | 5 |
| Baylor All Saints Medical Center | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 4 |
| Cook Children's Endocrinology | Hypochondroplasia, Idiopathic Short Stature | 4 |
| GI Alliance - Fort Worth | Metabolic Dysfunction-Associated Steatotic Liver Disease, Moderately to Severely Active Crohns Disease, Ulcerative Colitis | 4 |
| John Peter Smith Hospital | Drug-Related Side Effects and Adverse Reactions, Esophageal Squamous Cell Carcinoma, Nausea | 4 |
| North Texas Clinical Trials | AD, Alzheimer Disease, Cognitive Impairment | 4 |
| START Dallas | Advanced Malignancies, Cancer, G12D Mutated KRAS | 4 |
| START Dallas Fort Worth | Adenocarcinoma of Esophagus, Advanced Breast Cancer, Advanced Ovarian Cancer | 4 |
| Cook Children's | Hematopoietic Cell Transplant, Hemoglobinopathies, Respiratory Viral Infection | 4 |
| Cook Childrens Medical Center | Crohn's Disease, Hypoplastic Left Heart Syndrome (HLHS), Sickle Cell Disease | 3 |
| START Dallas Fort Worth, LLC | Castration-resistant Prostate Cancer, Castration-resistant Prostate Cancer (CRPC), Colorectal Cancer | 3 |
| Tarrant County Hospital District/JPS Health Network | Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 3 |
| Texas Oncology - DFW | Advanced Non-Small Cell Lung Cancer, Advanced Solid Tumor, Breast Cancer | 3 |
| Texas Oncology-Fort Worth Cancer Center | Endometrial Cancer, Leukemia, Lymphocytic, Chronic, B-Cell, Low Grade Serous Ovarian Cancer | 3 |
| Texas Retina Associates | Age-Related Macular Degeneration, Age-related Macular Degeneration (ARMD), Choroidal Neovascularization | 3 |
| The Center for Cancer and Blood Disorders | Anemia, Breast Cancer, Carcinoma, Non-Small-Cell Lung | 3 |
| University of North Texas Health Science Center | Chronic Low Back Pain, Hypertension, Memory Impairment | 3 |
| 89bio Clinical Study Site | Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis | 2 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, MASH With Fibrosis, NASH - Nonalcoholic Steatohepatitis | 2 |
Active & Upcoming Studies in Fort Worth (2026)
Recruiting trials in Fort Worth grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (123 active studies)
- A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer · Phase 2 · Verastem, Inc.
- Phase 1, Safety and Tolerability Study of XmAb541 and XmAb808 in Advanced Solid Tumors · Phase 1 · Xencor, Inc.
Cardiovascular (19 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- Occlutech AFR Fontan Study · Occlutech International AB
Diabetes & metabolic (15 active studies)
- A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Alone or in Combination With Dapagliflozin Compared With Placebo in Adults With Type 2 Diabetes Mellitus · Phase 3 · AstraZeneca
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
Neurology & pain (14 active studies)
- A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Chronic Low Back Pain · Phase 2 · Eli Lilly and Company
- A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Osteoarthritis Pain · Phase 2 · Eli Lilly and Company
Mental health & behavior (10 active studies)
- Justice Community Overdose Innovation Network II TCU Hub · Texas Christian University
- ALTO-207 in Adults With Treatment-resistant Depression (TRD) · Phase 2 · Alto Neuroscience
Eye & vision (8 active studies)
- A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration · Phase 3 · Amgen
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003) · Phase 2, Phase 3 · EyeBiotech Ltd.
Pediatric (6 active studies)
- Repetitive Transcranial Magnetic Stimulation on Motor Function and Meta-Plasticity in Cerebral Palsy: TMS-EEG Study · Cook Children's Health Care System
- KiteLock 4% EDTA Lock Solution for the Prevention of Occlusions in Children With Intestinal Failure · SterileCare Inc.
HIV / STI (1 active study)
- A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062) · Phase 2, Phase 3 · Merck Sharp & Dohme LLC
Common conditions studied in Fort Worth
- Endometrial Cancer (7 active studies). Recruiting Endometrial Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Heart Failure (7 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- ARDS (5 active studies). Recruiting ARDS studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Acute Respiratory Distress Syndrome (5 active studies). Recruiting Acute Respiratory Distress Syndrome studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Breast Cancer (5 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Breast Neoplasms (5 active studies). Recruiting Breast Neoplasms studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Fort Worth
- National Cancer Institute (NCI)
- Eli Lilly and Company
- Children's Oncology Group
- AstraZeneca
- Merck Sharp & Dohme LLC
Local regulations and guidelines
Clinical trials in Texas are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Trials run in Texas must also comply with the Texas Medical Privacy Act (TMPA), which extends federal HIPAA protections to a broader range of entities handling participant data.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Fort Worth. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Fort Worth
Hipa.ai aggregates every recruiting study in Fort Worth from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Fort Worth?
There are approximately 342 recruiting clinical trials in Fort Worth, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Fort Worth pay participants?
Most recruiting trials in Fort Worth compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Fort Worth?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Fort Worth?
The most common conditions under active study in Fort Worth include Endometrial Cancer (7), Heart Failure (7), ARDS (5), Acute Respiratory Distress Syndrome (5), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Fort Worth?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Fort Worth on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Fort Worth?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Fort Worth?
Recruiting research sites in Fort Worth include Cook Children's Medical Center, UT Southwestern/Simmons Cancer Center-Fort Worth, Cook Children's Health Care System, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Fort Worth right now?
The largest active categories in Fort Worth are Cancer & tumors (123), Cardiovascular (19), Diabetes & metabolic (15). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.