Paid Clinical Trials in McKinney, TX
As of July 2026, 69 paid clinical trials are recruiting in McKinney, Texas. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
McKinney offers studies at sites including Texas Institute of Cardiology for conditions such as Heart Failure, Asthma, Atrial Fibrillation (AF), Breast Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in McKinney
Trials by drug in McKinney
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Newly added in McKinney
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Study to Determine if BHV-1300 is Effective and Safe in Adults With Graves' Disease
A Study of WIN378 in Participants With Moderate to Severe COPD (Sirius)
62 clinical trials
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)
Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)
HP-211 Safety and Proof of Concept Dose Ranging Study in Patients With Type 2 Diabetes
Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Study to Assess the Effects of Angiopoietin-like Protein 3 (ANGPTL3) Inhibition in Adult Participants With Diabetic Kidney Disease
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-1)
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation
A Research Study to See How a Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine, Both in Combination With Insulin Aspart, in Adults With Type 1 Diabetes
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Assessment of CCM in HF With Higher Ejection Fraction
A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)
A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)
A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)
A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)
A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)
A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
A Study to Evaluate Solrikitug in Participants With COPD (ZION)
Efficacy and Safety of Extended TARPEYO® Treatment Beyond 9 Months in Adult Patients With Primary IgA Nephropathy
A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants With Graves' Disease
Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable
A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)
Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)
A Study of RSLV-132 in Females With Sjögren's Disease
Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis
Top Research Study Locations in McKinney
Researchers run research studies in McKinney, TX at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Texas Institute of Cardiology | Cardiovascular Disease, Heart Failure With Mildly Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction | 5 |
| North Dallas Research Associates | ASCVD, Cardiovascular Disease, Heart Failure | 4 |
| North Texas Research Associates | Heart Failure, Acute Myocardial Infarction, Obesity | 4 |
| Tekton Research | Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 1, Type 1 Diabetes Mellitus | 4 |
| Texas Oncology-Northeast Texas | Breast Cancer, Breast Neoplasms, Non-Small Cell Lung Cancer Metastatic | 3 |
| Metroplex Pulmonary and Sleep Center | Idiopathic Pulmonary Fibrosis (IPF), Interstitial Lung Disease, Progressive Pulmonary Fibrosis | 3 |
| Revival Research Institute, LLC | Atherosclerotic Cardiovascular Disease (ASCVD), Bipolar Disorder, Elevated Lp(a) | 2 |
| Clinical Trial Site | High Cardiovascular Risk, High Risk Cardiovascular Disease, Hypertension | 1 |
| Renal Disease Research Institute | Chronic Kidney Disease | 1 |
| Anthos Investigative | Atrial Fibrillation (AF) | 1 |
| Anthos Investigative | Atrial Fibrillation (AF) | 1 |
| Baylor Scott & White Medical Center - McKinney | Neonatal Hypoglycemia | 1 |
| Baylor Scott & White Neurology - McKinney | Generalized Myasthenia Gravis | 1 |
| Baylor Scott & White The Heart Hospital - Mckinney | Lower Extremity Arterial Disease, Peripheral Arterial Disease | 1 |
| Baylor Scott and White Med Ctr | Lumbar Spinal Stenosis | 1 |
| CardioVoyage | Cardiomyopathies, Heart Failure | 1 |
| Complete Heart Care P.A. | Atrial Fibrillation (AF) | 1 |
| Dallas Nephrology Associates McKinney | IgA Nephropathy | 1 |
| ENT Associates of Texas - McKinne | Chronic Rhinosinusitis With Nasal Polyps | 1 |
| Ear Nose and Throat Associates of Texas PA | Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) | 1 |
| Enveda Investigative Site | Asthma | 1 |
| Heart Rhythm Specialists | Diastolic Heart Failure, Heart Failure, Heart Failure With Mid Range Ejection Fraction | 1 |
| IntraCare Health Center | COPD | 1 |
| Ionis Investigative Site | Hypertriglyceridemia, Severe Hypertriglyceridemia | 1 |
| Kymera Investigative Site | Eosinophilic Asthma | 1 |
Active & Upcoming Studies in McKinney (2026)
Recruiting trials in McKinney grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cardiovascular (13 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable · Phase 3 · Regeneron Pharmaceuticals
Diabetes & metabolic (9 active studies)
- A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus · Phase 3 · AstraZeneca
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
Cancer & tumors (5 active studies)
- Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer · Phase 3 · Pfizer
- A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC) · Phase 3 · Pfizer
Mental health & behavior (3 active studies)
- A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD) · Phase 2 · Tonix Pharmaceuticals, Inc.
- Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT) · Bristol-Myers Squibb
Pediatric (1 active study)
- The Feasibility of Cream for Treatment of Neonatal Hypoglycemia · Baylor Research Institute
Common conditions studied in McKinney
- Heart Failure (6 active studies)
- Asthma (5 active studies)
- Atrial Fibrillation (AF) (3 active studies)
- Breast Cancer (3 active studies)
- Graves' Disease (3 active studies)
- Type 2 Diabetes Mellitus (3 active studies)
Leading research sponsors in McKinney
- AstraZeneca
- Pfizer
- Amgen
- Boehringer Ingelheim
- Eli Lilly and Company
Frequently asked questions
How many paid clinical trials are currently recruiting in McKinney?
There are approximately 69 recruiting clinical trials in McKinney, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in McKinney pay participants?
Most recruiting trials in McKinney compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in McKinney?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in McKinney?
The most common conditions under active study in McKinney include Heart Failure (6), Asthma (5), Atrial Fibrillation (AF) (3), Breast Cancer (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in McKinney?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in McKinney on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in McKinney?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in McKinney?
Recruiting research sites in McKinney include Texas Institute of Cardiology, North Dallas Research Associates, North Texas Research Associates, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in McKinney right now?
The largest active categories in McKinney are Cardiovascular (13), Diabetes & metabolic (9), Cancer & tumors (5). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.