Paid Clinical Trials in Richardson, TX
As of July 2026, 78 paid clinical trials are recruiting in Richardson, Texas. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Richardson offers studies at sites including UT Southwestern Clinical Center at Richardson/Plano for conditions such as Schizophrenia, Major Depressive Disorder (MDD), Stage IVB Prostate Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Richardson
Trials by drug in Richardson
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Newly added in Richardson
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Psychosocial Burden and Quality of Life in Caretakers of Hepatobiliary Cancer Patients
69 clinical trials
Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE.
A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive Disorder
A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer
A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
A Trial of the Efficacy and Safety of SEP-363856 in Acutely Psychotic Participants With Schizophrenia
A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2)
A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder
Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC
A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)
A Surveillance Study of Susceptibility to Baloxavir Marboxil in Pediatric Participants With Influenza and Transmission of Influenza to Household Contacts
An Extension Study to Assess Long-Term Safety and Tolerability of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia
A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)
A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression
A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine
A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder
Safety and Efficacy of Brilaroxazine (RP5063) in Schizophrenia
A Study of the Feasibility, Safety and Tolerability of Aticaprant as Adjunctive Treatment in Participants With Schizophrenia
Study to Evaluate Efficacy and Safety of Roluperidone in Adult Subjects With Negative Symptoms and Stable Positive Symptoms of Schizophrenia and to Evaluate the Relapse Rate of Roluperidone and Antipsychotic Medications
Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer
A Study to Assess Adverse Events, Change in Disease Activity, and How Oral Emraclidine Moves Through the Body in Adult Participants With Schizophrenia
Using Non-invasive Brain Stimulation to Explore Potential Treatments to Reduce Speech Errors in Adults Who Stutter
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study
APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma
Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial
Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer
Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging
Top Research Study Locations in Richardson
Researchers run research studies in Richardson, TX at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| UT Southwestern Clinical Center at Richardson/Plano | Stage IVB Prostate Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8, Endometrial Clear Cell Adenocarcinoma | 28 |
| Pillar Clinical Research - Richardson | Bipolar Disorder, Alcohol Use Disorder, Bipolar Disorder Type I With Mania | 9 |
| Pillar Clinical Research, LLC | Schizophrenia, Major Depressive Disorder, Negative Symptoms of Schizophrenia | 5 |
| University of Texas at Dallas | Autism, Major Depressive Disorder (MDD), Alcohol Use Disorder (AUD) | 5 |
| Methodist Richardson Medical Center | Esophageal Cancer, Gastrointestinal Disease, Gastroparesis | 3 |
| Pillar Clinical Research | Bipolar Disorder Type I With Mania or Mania With Mixed Features, Bipolar I Disorder, Schizophrenia | 3 |
| Texas Biomedical Device Center | Functional Mobility, Gait, Lower Limb Functions | 3 |
| The University of Texas at Dallas | Aphasia, Multiple Sclerosis, Relapsing-Remitting | 2 |
| Vanda Investigational Site | Major Depressive Disorder (MDD), Schizophrenia | 2 |
| Callier Center for Communication Disorders | Hearing Aids, Hearing Loss, Adult-Onset | 1 |
| Callier Clinical Center, The University of Texas at Dallas | PARKINSON DISEASE (Disorder) | 1 |
| Callier Clinical Research Center | Fluency Disorder, Stuttering | 1 |
| Draig Clinical Site | Major Depressive Disorder (MDD) | 1 |
| Methodist Hospital | COPD, Cancer, Chronic Hepatitis | 1 |
| Methodist Richardson Cancer Center | Metastatic Non-small Cell Lung Cancer | 1 |
| Methodist Richardson Medical Center- Clinical Research Institute | Psychosocial Problem | 1 |
| Naveen Jindal School of Management, The University of Texas at Dallas | Electronic Health Records | 1 |
| Oak Cliff Research Company, LLC | Influenza | 1 |
| Peak Health Surgicare of Horizon Medical Center | Lumbar Spinal Stenosis | 1 |
| Pillar Clinical Research LLC (Richardson, TX) Site | Schizophrenia | 1 |
| Reviva site | Schizophrenia | 1 |
| Seaport Investigator Site | Major Depressive Disorder (MDD), Major Depressive Disorder With Anxious Distress | 1 |
| TG Therapeutics Investigational Trial Site | Schizophrenia | 1 |
| Trinity Surgical Consultants, Methodist Richardson Medical Center | Benign or Malignant Pancreatic Diseases | 1 |
| UT Southwestern - Simmons Cancer Center - Richardson/Plano | Carcinoma, Non-Small-Cell Lung, Endometrial Cancer, Esophageal Squamous Cell Carcinoma | 1 |
Active & Upcoming Studies in Richardson (2026)
Recruiting trials in Richardson grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (32 active studies)
- Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer · Phase 2 · National Cancer Institute (NCI)
- A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer · Phase 3 · National Cancer Institute (NCI)
Mental health & behavior (18 active studies)
- A Study of LTX-001 In Adult Participants With Acute Exacerbation of Schizophrenia · Phase 1 · Leal Therapeutics, Inc
- Study to Evaluate the Safety and Efficacy of Ublituximab in Participants With Schizophrenia · Phase 2 · TG Therapeutics, Inc.
Neurology & pain (3 active studies)
- Treatment of Cognitive and Sensorimotor Deficits in Parkinson's Disease With High Definition Transcranial Direct Current Stimulation · The University of Texas at Dallas
- Treatment of Cognitive Deficits in Multiple Sclerosis With High-Definition Transcranial Direct Current Stimulation · The University of Texas at Dallas
Vaccines (1 active study)
HIV / STI (1 active study)
Diabetes & metabolic (1 active study)
Common conditions studied in Richardson
- Schizophrenia (9 active studies)
- Major Depressive Disorder (MDD) (5 active studies)
- Stage IVB Prostate Cancer AJCC v8 (5 active studies)
- Stage IV Renal Cell Cancer AJCC v8 (3 active studies)
- Autism (2 active studies)
- Bipolar Disorder (2 active studies)
Leading research sponsors in Richardson
- National Cancer Institute (NCI)
- The University of Texas at Dallas
- Alliance for Clinical Trials in Oncology
- Methodist Health System
- Bristol-Myers Squibb
Frequently asked questions
How many paid clinical trials are currently recruiting in Richardson?
There are approximately 78 recruiting clinical trials in Richardson, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Richardson pay participants?
Most recruiting trials in Richardson compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Richardson?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Richardson?
The most common conditions under active study in Richardson include Schizophrenia (9), Major Depressive Disorder (MDD) (5), Stage IVB Prostate Cancer AJCC v8 (5), Stage IV Renal Cell Cancer AJCC v8 (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Richardson?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Richardson on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Richardson?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Richardson?
Recruiting research sites in Richardson include UT Southwestern Clinical Center at Richardson/Plano, Pillar Clinical Research - Richardson, Pillar Clinical Research, LLC, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Richardson right now?
The largest active categories in Richardson are Cancer & tumors (32), Mental health & behavior (18), Neurology & pain (3). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.