Paid Clinical Trials in Richardson, TX
As of June 2026, 80 paid clinical trials are recruiting in Richardson, Texas. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Richardson offers studies at sites including UT Southwestern Clinical Center at Richardson/Plano for conditions such as Schizophrenia, Stage IVB Prostate Cancer AJCC v8, Major Depressive Disorder (MDD), Stage IIIB Lung Cancer AJCC v8. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Richardson
Trials by drug in Richardson
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79 clinical trials
↓ Download CSV52-week Open Label Safety-Tolerability Study
Study to Evaluate Efficacy and Safety of Roluperidone in Adult Subjects With Negative Symptoms and Stable Positive Symptoms of Schizophrenia and to Evaluate the Relapse Rate of Roluperidone and Antipsychotic Medications
Using Non-invasive Brain Stimulation to Explore Potential Treatments to Reduce Speech Errors in Adults Who Stutter
A Study of the Feasibility, Safety and Tolerability of Aticaprant as Adjunctive Treatment in Participants With Schizophrenia
A Study to Learn About the Study Medicine (PF-08653944) in People With Obesity or Overweight and Type 2 Diabetes (T2D)
A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder
Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE.
Efficacy and Safety of MET097 Once-Weekly in People With Overweight or Obesity
A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive Disorder
A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression
Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial
The Role of Framing and Choice Architecture in Patients' Reactions and EHR Error Discovery and Reporting
Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial
A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)
Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer
A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder
A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
Meeting the Needs of Young Hispanic Autistic Children
A Study to Assess Adverse Events, Change in Disease Activity, and How Oral Emraclidine Moves Through the Body in Adult Participants With Schizophrenia
Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Bipolar I Disorder
A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)
Use of Airpod Pros as Assistive Technology
A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)
A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2)
A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder
Randomized Withdrawal Study in Patients With Schizophrenia
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder
A Trial of the Efficacy and Safety of SEP-363856 in Acutely Psychotic Participants With Schizophrenia
Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial
Brain Health on College Campuses
Targeted Plasticity Therapy for PTSD
Testing the Addition of Immunotherapy Before Surgery for Patients With Sarcomatoid Mesothelioma
Word Learning From Parentese in Autistic Children
Vagus Nerve Stimulation (VNS) in Spinal Cord Injury (SCI) Adaptive Follow-On Study
LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC
Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial
About research studies in Richardson
Richardson has approximately 80 recruiting research studies across a wide range of therapeutic areas. Texas hosts major cancer and cardiovascular research centers including MD Anderson Cancer Center, Baylor College of Medicine, UT Southwestern Medical Center, and the Texas Medical Center — the largest medical complex in the world.
Top Research Study Locations in Richardson
Researchers run research studies in Richardson, TX at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| UT Southwestern Clinical Center at Richardson/Plano | Stage IVB Prostate Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8 | 34 |
| Pillar Clinical Research - Richardson | Bipolar Disorder, Alcohol Use Disorder, Bipolar 1 Disorder | 10 |
| Methodist Richardson Medical Center | Esophageal Cancer, Gastrointestinal Disease, Gastroparesis | 3 |
| Pillar Clinical Research, LLC | Schizophrenia, Negative Symptoms of Schizophrenia | 3 |
| University of Texas at Dallas | Autism, Autism Spectrum Disorder, Health Behavior | 3 |
| Dallas Clinical Research Center (Pillar Clinical Research) | Diabetes, Type 2, Obesity, Obesity and Overweight | 2 |
| Pillar Clinical Research | Bipolar I Disorder, Schizophrenia | 2 |
| Texas Biomedical Device Center | PTSD, Post Traumatic Stress Disorder, SCI - Spinal Cord Injury | 2 |
| The University of Texas at Dallas | Aphasia, Multiple Sclerosis, Relapsing-Remitting | 2 |
| Vanda Investigational Site | Major Depressive Disorder (MDD), Schizophrenia | 2 |
| Callier Center for Communication Disorders | Hearing Aids, Hearing Loss, Adult-Onset | 1 |
| Callier Clinical Research Center | Fluency Disorder, Stuttering | 1 |
| Draig Clinical Site | Major Depressive Disorder (MDD) | 1 |
| Local Institution - 0095 | Bipolar Disorder Type I With Mania or Mania With Mixed Features | 1 |
| Methodist Richardson Cancer Center | Metastatic Non-small Cell Lung Cancer | 1 |
| Methodist Richardson Medical Center- Clinical Research Institute | Psychosocial Problem | 1 |
| Naveen Jindal School of Management, The University of Texas at Dallas | Electronic Health Records | 1 |
| Oak Cliff Research Company, LLC | Influenza | 1 |
| Peak Health Surgicare of Horizon Medical Center | Lumbar Spinal Stenosis | 1 |
| Pillar Clinical Research LLC (Richardson, TX) Site | Schizophrenia | 1 |
| Reviva site | Schizophrenia | 1 |
| Seaport Investigator Site | Major Depressive Disorder (MDD), Major Depressive Disorder With Anxious Distress | 1 |
| Trinity Surgical Consultants, Methodist Richardson Medical Center | Benign or Malignant Pancreatic Diseases | 1 |
| UT Southwestern - Simmons Cancer Center - Richardson/Plano | Carcinoma, Non-Small-Cell Lung, Endometrial Cancer, Esophageal Squamous Cell Carcinoma | 1 |
| University of Texas Southwestern Medical Center Simmons Cancer Center - Richardson/Plano | Advanced Breast Cancer, Advanced Gastric Cancer, Breast Neoplasms | 1 |
Active & Upcoming Studies in Richardson (2026)
Recruiting trials in Richardson grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (37 active studies)
- Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial · Phase 3 · Alliance for Clinical Trials in Oncology
- Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial · Phase 2 · National Cancer Institute (NCI)
Mental health & behavior (18 active studies)
- 52-week Open Label Safety-Tolerability Study · Phase 3 · LB Pharmaceuticals Inc.
- Study to Evaluate Efficacy and Safety of Roluperidone in Adult Subjects With Negative Symptoms and Stable Positive Symptoms of Schizophrenia and to Evaluate the Relapse Rate of Roluperidone and Antipsychotic Medications · Phase 3 · Minerva Neurosciences
Diabetes & metabolic (2 active studies)
Neurology & pain (2 active studies)
- Treatment of Cognitive Deficits in Multiple Sclerosis With High-Definition Transcranial Direct Current Stimulation · The University of Texas at Dallas
- Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO · Phase 1 · National Cancer Institute (NCI)
Vaccines (1 active study)
Common conditions studied in Richardson
- Schizophrenia (7 active studies). Schizophrenia research tests muscarinic agonists, long-acting injectable antipsychotics, and cognitive remediation therapies.
- Stage IVB Prostate Cancer AJCC v8 (5 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
- Major Depressive Disorder (MDD) (3 active studies). Major depressive disorder research examines rapid-acting agents, augmentation strategies, and digital therapeutics for treatment-resistant cases.
- Stage IIIB Lung Cancer AJCC v8 (3 active studies). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.
- Stage IV Renal Cell Cancer AJCC v8 (3 active studies). Recruiting Stage IV Renal Cell Cancer AJCC v8 studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Autism (2 active studies). Recruiting Autism studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Richardson
- National Cancer Institute (NCI)
- The University of Texas at Dallas
- Alliance for Clinical Trials in Oncology
- ECOG-ACRIN Cancer Research Group
- Methodist Health System
Local regulations and guidelines
Clinical trials in Texas are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Trials run in Texas must also comply with the Texas Medical Privacy Act (TMPA), which extends federal HIPAA protections to a broader range of entities handling participant data.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Richardson. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Richardson
Hipa.ai aggregates every recruiting study in Richardson from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Richardson?
There are approximately 80 recruiting clinical trials in Richardson, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Richardson pay participants?
Most recruiting trials in Richardson compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Richardson?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Richardson?
The most common conditions under active study in Richardson include Schizophrenia (7), Stage IVB Prostate Cancer AJCC v8 (5), Major Depressive Disorder (MDD) (3), Stage IIIB Lung Cancer AJCC v8 (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Richardson?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Richardson on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Richardson?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Richardson?
Recruiting research sites in Richardson include UT Southwestern Clinical Center at Richardson/Plano, Pillar Clinical Research - Richardson, Methodist Richardson Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Richardson right now?
The largest active categories in Richardson are Cancer & tumors (37), Mental health & behavior (18), Diabetes & metabolic (2). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.