Paid Clinical Trials in League City, TX
As of July 2026, 40 paid clinical trials are recruiting in League City, Texas. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
League City offers studies at sites including UT MD Anderson - League City for conditions such as Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer, Metastatic Malignant Neoplasm in the Brain, Metastatic Renal Cell Carcinoma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in League City
Trials by drug in League City
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39 clinical trials
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies
A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.
This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis
A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)
A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors
Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension).
A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Primary Membranous Nephropathy (PMN)
Study of PF-07248144 in Advanced or Metastatic Solid Tumors
Two Arm, Double-blind, Phase III Study Assessing Efficacy and Safety of Ianalumab Versus Placebo, in Participants With Sjögren's Disease With High Symptom Burden
A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial
Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma
Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer
Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer
Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain
Testing the Combination of the Anticancer Drug Durvalumab With Chemotherapy (Gemcitabine and Cisplatin) at Improving Outcomes for High-Risk Resectable Liver Cancer Before Surgery
QuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 in HER2-low Metastatic Breast Cancer
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer
Chemotherapy With or Without Immunotherapy for Peritoneal Mesothelioma
Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer
SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer
Impact of COVID-19 Pandemic on Out-of-Pocket Costs, Lost Wages, and Unemployment in Patients With Breast Cancer Undergoing Breast Surgery
Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body
Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability
Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer
Top Research Study Locations in League City
Researchers run research studies in League City, TX at 11 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| UT MD Anderson - League City | Anatomic Stage II Breast Cancer AJCC v8, Metastatic Malignant Neoplasm in the Brain, Stage IV Lung Cancer AJCC v8 | 16 |
| MD Anderson League City | Stage IVB Prostate Cancer AJCC v8, Breast Cancer, Breast Ductal Carcinoma In Situ | 9 |
| The University of Texas, MD Anderson Cancer Center - League City | Advanced Breast Cancer, Advanced Non-Small Cell Lung Cancer, Advanced Renal Cell Carcinoma | 5 |
| University of Texas Medical Branch | Breast Cancer, Primary Membranous Nephropathy, Pneumococcal Infection | 3 |
| Accurate Clinical Research | Sjögren´s Disease, Systemic Lupus Erythematosus | 2 |
| Clear Falls High School | Athletic Injuries | 1 |
| League City | Endometriosis, Uterine Fibroids | 1 |
| MD Anderson Cancer center | HER2-positive Metastatic Breast Cancer | 1 |
| Maximos Ob/Gyn | Healthy | 1 |
| UTMB Cancer Center at Victory Lakes | Breast Cancer | 1 |
| UTMB Health League City Campus Hospital | Lumbar Spinal Stenosis | 1 |
Active & Upcoming Studies in League City (2026)
Recruiting trials in League City grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (30 active studies)
- Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer · Phase 1, Phase 2 · Pfizer
- A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors · Phase 1 · Pfizer
Vaccines (1 active study)
Common conditions studied in League City
- Anatomic Stage II Breast Cancer AJCC v8 (3 active studies)
- Breast Cancer (3 active studies)
- Metastatic Malignant Neoplasm in the Brain (2 active studies)
- Metastatic Renal Cell Carcinoma (2 active studies)
- Stage IV Lung Cancer AJCC v8 (2 active studies)
- Stage IVA Prostate Cancer AJCC v8 (2 active studies)
Leading research sponsors in League City
- NRG Oncology
- Pfizer
- National Cancer Institute (NCI)
- SWOG Cancer Research Network
- Alliance for Clinical Trials in Oncology
Frequently asked questions
How many paid clinical trials are currently recruiting in League City?
There are approximately 40 recruiting clinical trials in League City, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in League City pay participants?
Most recruiting trials in League City compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in League City?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in League City?
The most common conditions under active study in League City include Anatomic Stage II Breast Cancer AJCC v8 (3), Breast Cancer (3), Metastatic Malignant Neoplasm in the Brain (2), Metastatic Renal Cell Carcinoma (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in League City?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in League City on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in League City?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in League City?
Recruiting research sites in League City include UT MD Anderson - League City, MD Anderson League City, The University of Texas, MD Anderson Cancer Center - League City, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in League City right now?
The largest active categories in League City are Cancer & tumors (30), Vaccines (1). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.