Acute lymphoblastic leukemia Clinical Trials in Greenville, SC
As of June 2026, 2 paid clinical trials are recruiting for Acute lymphoblastic leukemia in Greenville, South Carolina. Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Related specialties in Greenville
Filter results
2 clinical trials for Acute lymphoblastic leukemia
·Clear filters·↓ Download CSVThe Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study
About research studies in Greenville
Greenville has approximately 307 recruiting research studies across a wide range of therapeutic areas. South Carolina hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.
Top Research Study Locations in Greenville
Researchers run research studies in Greenville, SC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Prisma Health Cancer Institute - Eastside | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8 | 57 |
| Prisma Health Cancer Institute - Faris | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8 | 57 |
| Prisma Health Cancer Institute - Butternut | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8 | 48 |
| BI-LO Charities Children's Cancer Center | B Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Down Syndrome | 32 |
| Prisma Health | Abdominal Aortic Aneurysm, End Stage Renal Disease, AML | 28 |
| Prisma Health Greenville Memorial Hospital | Malignant Solid Neoplasm, Melanoma, Stage IV Breast Cancer AJCC v6 and v7 | 27 |
| Saint Francis Cancer Center | Anatomic Stage IV Breast Cancer AJCC v8, Melanoma, Anatomic Stage III Breast Cancer AJCC v8 | 27 |
| Saint Francis Hospital | Anatomic Stage IV Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Breast Carcinoma | 23 |
| Tribe Clinical Research, LLC | Obesity, Overweight, Atopic Dermatitis | 10 |
| Prisma Health - Upstate | Acute Myocardial Infarction, Acute Stroke, Chronic Disease | 9 |
| Prisma Health Cancer Institute | Advanced Melanoma, Advanced Solid Tumor, Amyloid Cardiomyopathy | 9 |
| Prisma Health Upstate | Acute Limb Ischemia, Chronic Graft-versus-host-disease, Deep Venous Thrombosis | 7 |
| Prisma Health-Upstate | AAA - Abdominal Aortic Aneurysm, AV Block, Advanced Solid Tumor | 6 |
| PCPMG Clinical Research Unit, LLC | Chronic Pain, Chronic Leg Pain, Chronic Low-back Pain | 4 |
| Premier Neurology | Multiple Sclerosis (MS) Primary Progressive, Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD), Relapsing Multiple Sclerosis | 4 |
| Tribe Clinical Research LLC | Cardiovascular Diseases, Chronic Spontaneous Urticaria (CSU), Diabetes Mellitus, Type 2 | 4 |
| Gastroenterology Associates | Crohn's Disease, Moderately to Severely Active Crohns Disease, Moderately to Severely Active Ulcerative Colitis | 3 |
| Greenwood Genetic Center - Greenville- Site Number : 840055 | Cerebroside Lipidosis Syndrome, Fabry Disease, Gaucher Disease | 3 |
| Prisma Health Children's Hospital | Irritable Bowel Syndrome With Constipation (IBS-C) | 3 |
| Bon Secours - St. Francis Hospital | Breast Cancer, Muscle-invasive Urothelial Carcinoma | 2 |
| Bon Secours Medical Group Greenville Specialty Care, LLC | Heart Failure | 2 |
| GSK Investigational Site | Chickenpox, Neoplasms, Head and Neck | 2 |
| Gastroenterology Associates - Patewood | Obesity or Overweight, Crohn's Disease, Ulcerative Colitis | 2 |
| Greenville Hospital System University Medical Center (ITOR) | Advanced Solid Tumor, Refractory Non-Hodgkin Lymphoma, Solid Tumor | 2 |
| Greenville Memorial Hospital | Alcohol Use Disorder, Symptomatic Hypertrophic Cardiomyopathy (HCM) | 2 |
Active & Upcoming Studies in Greenville (2026)
Recruiting trials in Greenville grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (123 active studies)
- A Phase 1 Study of the Safety and Tolerability of CTX-10726 · Phase 1 · Compass Therapeutics
- Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII · Phase 2 · Black Diamond Therapeutics, Inc.
Neurology & pain (21 active studies)
- Continuous Dual Aspiration Technique With Zoom System for Stroke · Imperative Care, Inc.
- A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis · Phase 3 · Zenas BioPharma (USA), LLC
Diabetes & metabolic (20 active studies)
- A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight · Phase 2 · Eli Lilly and Company
- A Research Study to Compare Different Versions of Injectable CagriSema and Placebo in People With Excess Body Weight · Phase 3 · Novo Nordisk A/S
Cardiovascular (15 active studies)
- Implementation Facilitation of Exercise is Medicine Greenville · University of South Carolina
- Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease · Phase 3 · Alnylam Pharmaceuticals
Mental health & behavior (5 active studies)
- Electronic Cigarettes as a Harm Reduction Strategy Among People With Opioid Use Disorder on Buprenorphine · Prisma Health-Upstate
- STEPS: Substance Use Trial of E-cigarettes or Pharmacotherapy for Smoking · Medical University of South Carolina
Vaccines (3 active studies)
- A Study to Evaluate the Safety and Efficacy of CD388 for Prevention of Influenza · Phase 3 · Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
- A Phase 3 Study of Revaccination in Subsequent Pregnancies With Bivalent RSV Vaccine and Duration of Protection of a Single Dose · Phase 3 · Pfizer
Eye & vision (2 active studies)
- COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME · Phase 3 · EyePoint Pharmaceuticals, Inc.
- A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy · Phase 3 · Regeneron Pharmaceuticals
Pediatric (2 active studies)
- The CATSINDO Trial - Clinical and Translational Study in Newly Diagnosed Osteosarcoma · Phase 2 · Wake Forest University Health Sciences
- Randomized Study in Children and Adolescents With Migraine: Acute Treatment · Phase 3 · Pfizer
Common conditions studied in Greenville
- Acute Myeloid Leukemia (9 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Breast Cancer (8 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Heart Failure (7 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Advanced Solid Tumor (6 active studies). Recruiting Advanced Solid Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Cancer (6 active studies). Recruiting Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Obesity (6 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
Leading research sponsors in Greenville
- National Cancer Institute (NCI)
- Children's Oncology Group
- SWOG Cancer Research Network
- Alliance for Clinical Trials in Oncology
- AstraZeneca
Local regulations and guidelines
Clinical trials in South Carolina are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. South Carolina research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Greenville. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Greenville
Hipa.ai aggregates every recruiting study in Greenville from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Greenville?
There are approximately 307 recruiting clinical trials in Greenville, South Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Greenville pay participants?
Most recruiting trials in Greenville compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Greenville?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Greenville?
The most common conditions under active study in Greenville include Acute Myeloid Leukemia (9), Breast Cancer (8), Heart Failure (7), Advanced Solid Tumor (6), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Greenville?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Greenville on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Greenville?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Greenville?
Recruiting research sites in Greenville include Prisma Health Cancer Institute - Eastside, Prisma Health Cancer Institute - Faris, Prisma Health Cancer Institute - Butternut, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Greenville right now?
The largest active categories in Greenville are Cancer & tumors (123), Neurology & pain (21), Diabetes & metabolic (20). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.