Paid Clinical Trials in Harlingen, TX
As of June 2026, 36 paid clinical trials are recruiting in Harlingen, Texas. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Harlingen offers studies at sites including Texas Digestive Specialists for conditions such as Acute Ischemic Stroke, Eosinophilic Esophagitis, Lumbar Spinal Stenosis, Advanced Non-Small Cell Lung Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Harlingen
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·Clear filters·↓ Download CSVAbout research studies in Harlingen
Harlingen has approximately 36 recruiting research studies across a wide range of therapeutic areas. Texas hosts major cancer and cardiovascular research centers including MD Anderson Cancer Center, Baylor College of Medicine, UT Southwestern Medical Center, and the Texas Medical Center — the largest medical complex in the world.
Top Research Study Locations in Harlingen
Researchers run research studies in Harlingen, TX at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Texas Digestive Specialists | Eosinophilic Esophagitis, Irritable Bowel Syndrome With Constipation (IBS-C), Moderately to Severely Active Crohn Disease | 4 |
| Cano Medical Center | Moderately to Severely Active Crohns Disease, Moderately to Severely Active Ulcerative Colitis | 2 |
| Integrative Rheumatology of South Texas | Lumbar Spinal Stenosis, Myositis, Sciatica Acute | 2 |
| Texas Oncology - Central South | Advanced Renal Cell Carcinoma, Advanced or Metastatic Renal Cell Carcinoma, Carcinoma, Renal Cell | 2 |
| Texas Oncology - Central/South Texas | Advanced Non-Small Cell Lung Cancer, Advanced/Metastatic Urothelial Cancer, Carcinoma, Non-Small-Cell Lung | 2 |
| Valley Baptist Medical Center - Harlingen | Acute Ischemic Stroke | 2 |
| Valley Institute of Research | Ulcerative Colitis, Chronic Obstructive Pulmonary Disease | 2 |
| 89bio Clinical Study Site | Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis | 1 |
| American Arthritis and Rheumatology Associates-Tx PLLC | Rheumatoid Arthritis | 1 |
| Dr. Falk Investigational Site | Eosinophilic Esophagitis | 1 |
| Forefront Med Res Inst PLLC | Obesity, Overweight | 1 |
| Hafizur Rahman | Foot Pain | 1 |
| Integrative Rheumatology of South Texas - Harlingen | Dry Eye Syndrome, Systemic Lupus Erythematosus | 1 |
| Local Institution - 0305 | Non-small Cell Lung Cancer | 1 |
| Naiara Alvarez MD Integrative Rheumatology of South TX | Arthritis, Psoriatic | 1 |
| Optimum Pain & Regenerative Medicine | Lumbar Spinal Stenosis | 1 |
| Platinum Surgery Center | Lumbar Spinal Stenosis | 1 |
| SportsOrtho Surg Ctr | Lumbar Spinal Stenosis | 1 |
| Texas Digestive | Cancer | 1 |
| Texas Oncology - Harlingen | Breast Cancer, Breast Cancer Metastatic, Breast Neoplasm | 1 |
| Texas Oncology - Harlingen, Medical Arts Pavillion | Melanoma | 1 |
| Texas Oncology- Central South | Non-Small Cell Lung Cancer Metastatic, Non-Small Cell Lung Carcinoma, Non-small Cell Carcinoma | 1 |
| USOR - Texas Oncology | Endometrial Cancer, Recurrent or Progressive Endometrial Cancer | 1 |
| University of Texas - Rio Grande Valley | Spinal Cord Injuries | 1 |
| University of Texas Rio Grande Valley | Hammertoe | 1 |
Active & Upcoming Studies in Harlingen (2026)
Recruiting trials in Harlingen grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (11 active studies)
- Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer · Phase 1, Phase 2 · Pfizer
- Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer · Phase 1, Phase 2 · Pfizer
Neurology & pain (4 active studies)
- The Pivotal Study of RapidPulseTM Aspiration System · RapidPulse, Inc
- Study of BB-031 in Acute Ischemic Stroke Patients (RAISE) · Phase 2 · Basking Biosciences, Inc.
Diabetes & metabolic (2 active studies)
Common conditions studied in Harlingen
- Acute Ischemic Stroke (2 active studies). Stroke trials test acute reperfusion strategies, neuroprotective agents, and rehabilitation technologies to improve recovery.
- Eosinophilic Esophagitis (2 active studies). Recruiting Eosinophilic Esophagitis studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Lumbar Spinal Stenosis (2 active studies). Recruiting Lumbar Spinal Stenosis studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Advanced Non-Small Cell Lung Cancer (1 active study). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.
- Advanced Renal Cell Carcinoma (1 active study). Recruiting Advanced Renal Cell Carcinoma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Advanced or Metastatic Renal Cell Carcinoma (1 active study). Recruiting Advanced or Metastatic Renal Cell Carcinoma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Harlingen
- Pfizer
- Sanofi
- Hoffmann-La Roche
- University of Texas Rio Grande Valley
- 89bio, Inc.
Local regulations and guidelines
Clinical trials in Texas are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Trials run in Texas must also comply with the Texas Medical Privacy Act (TMPA), which extends federal HIPAA protections to a broader range of entities handling participant data.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Harlingen. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Harlingen
Hipa.ai aggregates every recruiting study in Harlingen from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Harlingen?
There are approximately 36 recruiting clinical trials in Harlingen, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Harlingen pay participants?
Most recruiting trials in Harlingen compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Harlingen?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Harlingen?
The most common conditions under active study in Harlingen include Acute Ischemic Stroke (2), Eosinophilic Esophagitis (2), Lumbar Spinal Stenosis (2), Advanced Non-Small Cell Lung Cancer (1), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Harlingen?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Harlingen on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Harlingen?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Harlingen?
Recruiting research sites in Harlingen include Texas Digestive Specialists, Cano Medical Center, Integrative Rheumatology of South Texas, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Harlingen right now?
The largest active categories in Harlingen are Cancer & tumors (11), Neurology & pain (4), Diabetes & metabolic (2). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.