Behavioral health Clinical Trials in Houston, TX
As of July 2026, 70 paid clinical trials are recruiting for Behavioral health in Houston, Texas. Behavioral health trials span mental-health pharmacotherapy and addiction treatment — testing new agents and therapies for depression, anxiety, opioid use disorder, alcohol use, and tobacco cessation. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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70 clinical trials for Behavioral health
·Clear filters·↓ Download CSV"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"
A Study of Brenipatide in Participants With Alcohol Use Disorder
An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1)
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
Symptoms and Functions in Patients With COPD and Chronic Bronchitis Switching From CIG to THS
A Study of Brenipatide in Participants With Opioid Use Disorder
A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
An Extension Study to Assess Long-Term Safety and Tolerability of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia
Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)
NBI-1117568-SCZ3032: Long-Term Evaluation of NBI-1117568 in Adults With Schizophrenia
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine
ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response
A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)
NBI-1117568-SCZ3029: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia
Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
A Study to Determine the Effects of ENDS Flavor Availability on Abstinence Within Smokers
tAN for Substance Use Disorder
Expansion and Evaluation of AI-generated Clinical Assessment (AI-COA®) of Depression and Anxiety Severity
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
Suvorexant for Treatment of AUD and PTSD
Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 2)
Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 1)
Reducing Alcohol Exposed Pregnancies
Magnetic Seizure Therapy in Bipolar Depression (MST-BpD) and Treatment Resistant Depression (MST-TRD)
Reducing Posttraumatic Stress Disorder (PTSD) Symptoms in First Responders and Frontline Health Care Workers
Circuitry-Guided Smoking Cessation in Schizophrenia (UH3)
Young Houston Emergency Opioid Engagement System
Pilot Study of Virtual Reality Therapy for Students With Anxiety
Semaglutide for Post-Smoking Cessation Weight Management
Baseline Anxiety Trajectories in Pediatric Radiation Therapy Observational Cohort
Smart Olfaction App to Reduce Relapse
The Effectiveness of Individualized Imagery Scripts on Sleep, Psychosis, and Suicidality Among Inpatients With Psychosis
Neurobehavioral Therapy For Epilepsy And Major Depressive Disorder
Improving Behavioral Health for Caregivers and Children After Pediatric Injury
About research studies in Houston
Houston has approximately 3,171 recruiting research studies across a wide range of therapeutic areas. Texas hosts major cancer and cardiovascular research centers including MD Anderson Cancer Center, Baylor College of Medicine, UT Southwestern Medical Center, and the Texas Medical Center — the largest medical complex in the world.
Top Research Study Locations in Houston
Researchers run research studies in Houston, TX at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| MD Anderson Cancer Center | Colorectal Cancer, Ovarian Cancer, Breast Cancer | 438 |
| M D Anderson Cancer Center | Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm, Acute Myeloid Leukemia | 279 |
| Baylor College of Medicine | Epilepsy, Heart Failure, Amyotrophic Lateral Sclerosis | 204 |
| The University of Texas Health Science Center at Houston | Systemic Sclerosis, HIV Infections, Systemic Lupus Erythematosus | 188 |
| The University of Texas MD Anderson Cancer Center | Advanced Solid Tumor, Breast Cancer, Acute Myeloid Leukemia | 139 |
| Houston Methodist Hospital | Acute Respiratory Distress Syndrome, ARDS, ARDS (Acute Respiratory Distress Syndrome) | 135 |
| Texas Children's Hospital | Diffuse Intrinsic Pontine Glioma, High Grade Glioma, WHO Grade III Glioma | 118 |
| The University of Texas M. D. Anderson Cancer Center | Cancer, Breast Cancer, Prostate Cancer | 86 |
| University of Texas MD Anderson Cancer Center | Non-small Cell Lung Cancer, Breast Cancer, Carcinoma, Non-Small-Cell Lung | 84 |
| Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center | Acute Myeloid Leukemia, Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8 | 64 |
| UT MD Anderson Cancer Center | Metastatic Malignant Solid Neoplasm, Unresectable Malignant Solid Neoplasm, Advanced Malignant Solid Neoplasm | 63 |
| MD Anderson | Breast Cancer, Myelodysplastic Syndromes, Myelofibrosis | 40 |
| Houston Methodist | Heart Failure, Interstitial Lung Disease, Pulmonary Hypertension | 34 |
| Michael E. DeBakey VA Medical Center, Houston, TX | Spinal Cord Injury, Depression, Metastatic Prostate Cancer | 30 |
| Ben Taub General Hospital | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 26 |
| University of Texas Health Science Center at Houston | Infant, Small for Gestational Age, Infant, Low Birth Weight, Infant, Newborn | 26 |
| Houston Methodist Research Institute | Hepatocellular Carcinoma, AAA, AAA - Abdominal Aortic Aneurysm | 25 |
| UT MD Anderson | Breast Cancer, AML, Acute Myeloid Leukemia | 22 |
| GSK Investigational Site | Chickenpox, HIV Infections, Gastrointestinal Neoplasms | 18 |
| The University of Texas M.D. Anderson Cancer Center | Advanced Breast Cancer, Breast Cancer, Metastatic Breast Cancer | 18 |
| Houston Methodist West Hospital | Anatomic Stage II Breast Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, AL Amyloidosis | 17 |
| Oncology Consultants | Ovarian Cancer, Breast Cancer, Endometrial Cancer | 17 |
| MD Anderson West Houston | Metastatic Malignant Neoplasm in the Brain, Stage IV Lung Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8 | 16 |
| Prolato Clinical Research Center | Primary Membranous Nephropathy, Active Refractory Rheumatoid Arthritis, Arthritis, Rheumatoid | 16 |
| UTHealth Houston | Acute Suicidal Depression (ASD), Charcot-Marie-Tooth Disease Type 2D, Chronic Subdural Hematoma | 16 |
Active & Upcoming Studies in Houston (2026)
Recruiting trials in Houston grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (1,253 active studies)
- A Phase 1b/2 Open-label, Dose-ranging Safety and Efficacy Study of Oral Cladribine in Patients With Acute Myeloid Leukemia (AML) · Phase 1, Phase 2 · M.D. Anderson Cancer Center
- Phase 1 Study Of TROP2 CAR/IL-15 TGFBR2 KO NK Cell In Patients With Oral Premalignant Lesions · Phase 1 · M.D. Anderson Cancer Center
Neurology & pain (150 active studies)
- Neuro-Intermuscular Coordination Enhancement (NICE) Rehabilitation Through Human-Machine Interaction in Chronic Stroke · EARLY_Phase 1 · University of Houston
- BreEStim in Managing Neuropathic Pain After Spinal Cord Injury (SCI) · The University of Texas Health Science Center, Houston
Diabetes & metabolic (106 active studies)
- Benefits of Insoles With Real-Time Alert and Foot Self-Care Education · Texas Woman's University
- A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide · Phase 3 · Novo Nordisk A/S
Cardiovascular (100 active studies)
- HiCM-188 Cell Therapy in Adults With Advanced Heart Failure Undergoing Heart Bypass Surgery · Phase 1, Phase 2 · HELP Therapeutics Co., Ltd.
- A Prospective, Randomized Multicenter Clinical Trial of the TricValve® Transcatheter Bicaval Valve System in Subjects With Severe Tricuspid Regurgitation. · P+F Products + Features USA Inc.
Mental health & behavior (86 active studies)
- ACT for Veterans With IBD and Mental Health Challenges · VA Office of Research and Development
- Pilot Randomized Trial of BA-GSH in VA PC-MHI · VA Office of Research and Development
Pediatric (47 active studies)
- Feasibility Trial of the Womb Watch Smartphone App To Assess Fetal Movements · Kenneth Moise MD
- Prospective Observational Study of Outcomes After Gemcitabine, Docetaxel, Melphalan, and Carboplatin With Autologous Stem Cell Transplantation in Pediatric Relapsed/Refractory Germ Cell Tumors · M.D. Anderson Cancer Center
HIV / STI (30 active studies)
- Improving HIV Prevention and Substance Use Post-Sexual Assault Services · The University of Texas Health Science Center, Houston
- A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
Vaccines (27 active studies)
- A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Administered as Intramuscular Injection to Healthy Children 15 Months to 6 Years of Age · Phase 3 · GlaxoSmithKline
- Remdesivir for the Treatment of Upper Respiratory Tract Infection Due to RSV in Immunocompromised Individuals · Phase 2 · Fred Hutchinson Cancer Center
Eye & vision (24 active studies)
- A Comparative, Randomized, Investigator-blind, Active-controlled, Parallel-group, Multicenter, Clinical Endpoint Study · Phase 3 · YS Life Science Co., Ltd.
- A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration · Phase 3 · Amgen
Common conditions studied in Houston
- Breast Cancer (82 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Acute Myeloid Leukemia (58 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Advanced Solid Tumor (56 active studies). Recruiting Advanced Solid Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Ovarian Cancer (52 active studies). Ovarian cancer research examines PARP inhibitors, maintenance therapies, and antibody-drug conjugates for recurrent and platinum-resistant disease.
- Colorectal Cancer (47 active studies). Colorectal cancer trials explore novel chemotherapy combinations, targeted agents, and immunotherapy for microsatellite-instability-high tumors.
- Prostate Cancer (46 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
Leading research sponsors in Houston
- M.D. Anderson Cancer Center
- The University of Texas Health Science Center, Houston
- Baylor College of Medicine
- AstraZeneca
- The Methodist Hospital Research Institute
Local regulations and guidelines
Clinical trials in Texas are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Trials run in Texas must also comply with the Texas Medical Privacy Act (TMPA), which extends federal HIPAA protections to a broader range of entities handling participant data.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Houston. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Houston
Hipa.ai aggregates every recruiting study in Houston from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Houston?
There are approximately 3,171 recruiting clinical trials in Houston, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Houston pay participants?
Most recruiting trials in Houston compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Houston?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Houston?
The most common conditions under active study in Houston include Breast Cancer (82), Acute Myeloid Leukemia (58), Advanced Solid Tumor (56), Ovarian Cancer (52), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Houston?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Houston on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Houston?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Houston?
Recruiting research sites in Houston include MD Anderson Cancer Center, M D Anderson Cancer Center, Baylor College of Medicine, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Houston right now?
The largest active categories in Houston are Cancer & tumors (1,253), Neurology & pain (150), Diabetes & metabolic (106). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.