Behavioral health Clinical Trials in Houston, TX
As of September 2026, 66 paid clinical trials are recruiting for Behavioral health in Houston, Texas. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Houston
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
67 clinical trials for Behavioral health
·Clear filters·An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1)
A Study of Brenipatide in Participants With Opioid Use Disorder
Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)
A Study of Brenipatide in Participants With Alcohol Use Disorder
A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)
Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia, Bipolar Disorder or Autism Spectrum Disorder
Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
NBI-1117568-SCZ3032: Long-Term Evaluation of NBI-1117568 in Adults With Schizophrenia
A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in Children and Adolescents
ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response
A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)
A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine
NBI-1117568-SCZ3029: Evaluation of NBI-1117568 in Inpatient Adults With Schizophrenia
Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
A Study to Determine the Effects of ENDS Flavor Availability on Abstinence Within Smokers
tAN for Substance Use Disorder
Expansion and Evaluation of AI-generated Clinical Assessment (AI-COA®) of Depression and Anxiety Severity
Baseline Anxiety Trajectories in Pediatric Radiation Therapy Observational Cohort
Semaglutide for Post-Smoking Cessation Weight Management
Circuitry-Guided Smoking Cessation in Schizophrenia (UH3)
Multifaceted Intervention to Restore Resilience and Overcome Risk
Reducing Dropout and Improving Outcomes From PTSD Therapy: When to Switch Therapies or Stay the Course
Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance Therapy
Neurodevelopmental Outcomes in Children: Strengthening the Caregiver-Child Story
TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors
CBT Augmentation to Promote Medication Discontinuation in Pediatric OCD
Telehealth Behavioral Activation for Teens
Gamma Oscillations as a Prognostic Marker for Ketamine Therapy in Treatment Resistant Depression
Reducing Posttraumatic Stress Disorder (PTSD) Symptoms in First Responders and Frontline Health Care Workers
Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 2)
Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 1)
Bayesian Neurobehavioral Phenotyping: From Mechanism Identification to Personalized Neuromodulation Treatments. R61 PHASE
Improving Behavioral Health for Caregivers and Children After Pediatric Injury
Suvorexant for Treatment of AUD and PTSD
Top Research Study Locations in Houston
Researchers run research studies in Houston, TX at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| MD Anderson Cancer Center | Colorectal Cancer, Ovarian Cancer, Acute Myeloid Leukemia | 417 |
| M D Anderson Cancer Center | Hematopoietic and Lymphoid Cell Neoplasm, Acute Myeloid Leukemia, Malignant Solid Neoplasm | 252 |
| Baylor College of Medicine | Epilepsy, Breast Cancer, Heart Failure | 192 |
| The University of Texas Health Science Center at Houston | Cluster Headache, HIV Infections, Systemic Sclerosis | 184 |
| The University of Texas MD Anderson Cancer Center | Advanced Solid Tumor, Breast Cancer, Colorectal Cancer | 136 |
| Houston Methodist Hospital | Acute Respiratory Distress Syndrome, ARDS, ARDS (Acute Respiratory Distress Syndrome) | 129 |
| Texas Children's Hospital | Diffuse Intrinsic Pontine Glioma, High Grade Glioma, WHO Grade III Glioma | 109 |
| The University of Texas M. D. Anderson Cancer Center | Cancer, Breast Cancer, Prostate Cancer | 84 |
| University of Texas MD Anderson Cancer Center | Breast Cancer, Non-small Cell Lung Cancer, Chronic Lymphocytic Leukemia | 82 |
| UT MD Anderson Cancer Center | Metastatic Malignant Solid Neoplasm, Unresectable Malignant Solid Neoplasm, Malignant Solid Neoplasm | 77 |
| Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center | Acute Myeloid Leukemia, Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8 | 56 |
| MD Anderson | Myelodysplastic Syndromes, Myelofibrosis, Acute Myeloid Leukemia | 39 |
| Houston Methodist | Heart Failure, Cardiovascular Diseases, Heart Valve Diseases | 33 |
| Michael E. DeBakey VA Medical Center, Houston, TX | Spinal Cord Injury, Metastatic Prostate Cancer, Stress Disorders, Post-Traumatic | 31 |
| University of Texas Health Science Center at Houston | Infant, Small for Gestational Age, Infant, Low Birth Weight, Infant, Newborn | 29 |
| UT MD Anderson | Breast Cancer, Pancreatic Cancer, AML | 28 |
| Ben Taub General Hospital | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 25 |
| Houston Methodist Research Institute | Hepatocellular Carcinoma, AAA, AAA - Abdominal Aortic Aneurysm | 22 |
| GSK Investigational Site | Chickenpox, HIV Infections, Gastrointestinal Neoplasms | 19 |
| The University of Texas M.D. Anderson Cancer Center | Advanced Breast Cancer, Breast Cancer, Metastatic Breast Cancer | 17 |
| Houston Methodist West Hospital | Anatomic Stage II Breast Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, AL Amyloidosis | 16 |
| UTHealth Houston | Acute Suicidal Depression (ASD), Charcot-Marie-Tooth Disease Type 2D, Emergency Department Visits | 16 |
| Michael E. DeBakey VA Medical Center | Gulf War Syndrome, Adult Growth Hormone Deficiency, Alzheimer Disease | 15 |
| Memorial Hermann Texas Medical Center | Acute Kidney Injury, Ischemic Stroke, Ovarian Carcinoma | 14 |
| Memorial Hermann Hospital | Acute Ischemic Stroke, Surgery, COVID-19 Infection | 13 |
Active & Upcoming Studies in Houston (2026)
Recruiting trials in Houston grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (1,179 active studies)
- A Phase 1 Open-Label, Dose-Ranging Safety and Pharmacokinetics Study of Oral Cladribine in Patients With Acute Myeloid Leukemia (AML) · Phase 1, Phase 2 · M.D. Anderson Cancer Center
- Proactively Intervening On Early Cranial Nerve Injury As A Delayed Sequela Of Oropharyngeal Cancer: A Randomized Feasibility Clinical Trial For Pro-Habilitation (proNERVE RCT) · Phase 1 · M.D. Anderson Cancer Center
Neurology & pain (138 active studies)
- Neuro-Intermuscular Coordination Enhancement (NICE) Rehabilitation Through Human-Machine Interaction in Chronic Stroke · EARLY_Phase 1 · University of Houston
- Prospective Randomized Study of TPS + CBT VS TPS Alone: Readmission, Opioid Use, and Chronic Pain · M.D. Anderson Cancer Center
Cardiovascular (105 active studies)
- Novel Technologies to Improve Echocardiographic Estimates of Left Ventricular Filling Pressure in Heart Failure Combined With Atrial Fibrillation · Oslo University Hospital
- HiCM-188 Cell Therapy in Adults With Advanced Heart Failure Undergoing Heart Bypass Surgery · Phase 1, Phase 2 · HELP Therapeutics Co., Ltd.
Diabetes & metabolic (103 active studies)
- Semaglutide, Weight Loss, and LNG-IUD for Conservative Treatment of Endometrial Atypical Hyperplasia and Grade 1 Endometrial Cancer · Phase 2 · The Methodist Hospital Research Institute
- Benefits of Insoles With Real-Time Alert and Foot Self-Care Education · Texas Woman's University
Mental health & behavior (80 active studies)
- ACT for Veterans With IBD and Mental Health Challenges · VA Office of Research and Development
- Pilot Randomized Trial of BA-GSH in VA PC-MHI · VA Office of Research and Development
Pediatric (45 active studies)
- Food is Medicine in Survivorship: Examining the Feasibility and Impact of a Scalable Food Delivery and Culinary Medicine Program (FoodiiS) Among Pediatric Cancer Survivors and Their Families · M.D. Anderson Cancer Center
- Feasibility Trial of the Womb Watch Smartphone App To Assess Fetal Movements · Kenneth Moise MD
HIV / STI (33 active studies)
- Improving HIV Prevention and Substance Use Post-Sexual Assault Services · The University of Texas Health Science Center, Houston
- A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
Vaccines (27 active studies)
- A Safety, Reactogenicity and Immunogenicity Trial of RVX-sCPD9 Booster Intranasal COVID-19 Vaccine · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age · Phase 3 · GlaxoSmithKline
Eye & vision (22 active studies)
- Treating Contact Lens Discomfort With Varenicline Solution Nasal Spray 0.03mg · Ocular Aesthetics, LLC dba Ocular Clinical Trials
- A Study to Evaluate Efficacy and Safety of YSBP Compared to Lumigan in Patients With Glaucoma or Ocular Hypertension · Phase 3 · YS Life Science Co., Ltd.
Common conditions studied in Houston
- Breast Cancer (76 active studies)
- Acute Myeloid Leukemia (54 active studies)
- Advanced Solid Tumor (52 active studies)
- Colorectal Cancer (47 active studies)
- Ovarian Cancer (47 active studies)
- Prostate Cancer (45 active studies)
Leading research sponsors in Houston
- M.D. Anderson Cancer Center
- The University of Texas Health Science Center, Houston
- Baylor College of Medicine
- AstraZeneca
- The Methodist Hospital Research Institute
Frequently asked questions
How many paid clinical trials are currently recruiting in Houston?
There are approximately 3,049 recruiting clinical trials in Houston, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Houston pay participants?
Most recruiting trials in Houston compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Houston?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Houston?
The most common conditions under active study in Houston include Breast Cancer (76), Acute Myeloid Leukemia (54), Advanced Solid Tumor (52), Colorectal Cancer (47), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Houston?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Houston on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Houston?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Houston?
Recruiting research sites in Houston include MD Anderson Cancer Center, M D Anderson Cancer Center, Baylor College of Medicine, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Houston right now?
The largest active categories in Houston are Cancer & tumors (1,179), Neurology & pain (138), Cardiovascular (105). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.