Cancer (any) Clinical Trials in Houston, TX
As of July 2026, 76 paid clinical trials are recruiting for Cancer (any) in Houston, Texas. Recruiting Cancer (any) studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Houston
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
77 clinical trials for Cancer (any)
·Clear filters·↓ Download CSVLong-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
FOG-001 in Locally Advanced or Metastatic Solid Tumors
Prospective Study to Assess a Diagnostic Aid for Cancer
A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms
A Study of PHN-012 in Patients With Advanced Solid Tumors
A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)
Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer
Abiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer.
ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors
A Study of JZP815 Oral Capsules in Adult Participants With Advanced or Metastatic Solid Tumors Harboring Mitogen Activated Protein Kinase (MAPK) Pathway Alterations to Investigate the Safety, Dosing, and Antitumor Activity of JZP815
A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations
Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer
Adoptive Cell Therapy Long-term Follow-up (LTFU) Study
Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer
Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies
A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors
A Study of JNJ-1761981 in Participants With Solid Tumors
A Study to Evaluate the Safety and Efficacy of MK-3120 in Participants With Advanced Solid Tumors (MK-3120-002)
A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)
A Study of JNJ-87704916, as Monotherapy and in Combination for Advanced Solid Tumors
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Clinical Activity of RO7673396 in Participants With Advanced Solid Tumors Harboring Rat Sarcoma Viral Oncogene Homolog (RAS) Mutation(s)
A Study of TSN1611 Treating Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation
A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy
A Study of MGC026 in Participants With Advanced Solid Tumors
A Prospective Registry to Enable Collection of Standardized Routine Care Oncology Patient Data
Comprehensive Outcomes for After Cancer Health
Trial of DFP-14927 in Advanced Solid Tumors
EMB-01 in Patients With Advanced/Metastatic Gastrointestinal Cancers
A Study in Patients With Advanced Cancers
Trial of Spiritual Care Interventions for Patients With Cancer
The Cancer Stage Shifting Initiative: Registry and Biorepository to Research and Address Health Disparities in Cancer Care
Phase 1 Study of JV-394 Autologous Anti-CD94 CAR T for r/r CD94+ T/NK Cell Neoplasms
Phase 1b Trial of BMS-986504 in Combination With Olaparib in Patients With MTAP Loss
A Chaplain-clinician Led Spiritual Care (PEACE) Intervention on Spiritual/Religious Beliefs Related to Medical Care in Patients With Advanced Cancer: a Pilot Clinical Trial
A Prospective Single Center, Single Arm, Single-institution Registry That Aims to Assess the Safety and Quality of Life Benefits of Computer-assisted Vacuum Thrombectomy (CAVT) in the Treatment of Cancer Patients With Intermediate Risk Pulmonary Embolism (PE)
Spiritual Care or Psychotherapy Versus Palliative Care Alone in Patients With Non-Curative Malignancies
About research studies in Houston
Houston has approximately 3,031 recruiting research studies across a wide range of therapeutic areas. Texas hosts major cancer and cardiovascular research centers including MD Anderson Cancer Center, Baylor College of Medicine, UT Southwestern Medical Center, and the Texas Medical Center — the largest medical complex in the world.
Top Research Study Locations in Houston
Researchers run research studies in Houston, TX at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| MD Anderson Cancer Center | Colorectal Cancer, Breast Cancer, Ovarian Cancer | 422 |
| M D Anderson Cancer Center | Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm, Acute Myeloid Leukemia | 273 |
| Baylor College of Medicine | Epilepsy, Heart Failure, Amyotrophic Lateral Sclerosis | 197 |
| The University of Texas Health Science Center at Houston | Systemic Sclerosis, HIV Infections, Systemic Lupus Erythematosus | 185 |
| The University of Texas MD Anderson Cancer Center | Advanced Solid Tumor, Breast Cancer, Colorectal Cancer | 131 |
| Houston Methodist Hospital | Acute Respiratory Distress Syndrome, ARDS, ARDS (Acute Respiratory Distress Syndrome) | 128 |
| Texas Children's Hospital | Diffuse Intrinsic Pontine Glioma, High Grade Glioma, WHO Grade III Glioma | 113 |
| The University of Texas M. D. Anderson Cancer Center | Cancer, Breast Cancer, Prostate Cancer | 85 |
| University of Texas MD Anderson Cancer Center | Breast Cancer, Non-small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung | 83 |
| UT MD Anderson Cancer Center | Metastatic Malignant Solid Neoplasm, Unresectable Malignant Solid Neoplasm, Advanced Malignant Solid Neoplasm | 61 |
| Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center | Acute Myeloid Leukemia, Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8 | 58 |
| MD Anderson | Myelodysplastic Syndromes, Myelofibrosis, Acute Myeloid Leukemia | 38 |
| Houston Methodist | Heart Failure, Cardiovascular Diseases, Heart Valve Diseases | 32 |
| Michael E. DeBakey VA Medical Center, Houston, TX | Spinal Cord Injury, Depression, Metastatic Prostate Cancer | 30 |
| Ben Taub General Hospital | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 25 |
| Houston Methodist Research Institute | Hepatocellular Carcinoma, AAA, AAA - Abdominal Aortic Aneurysm | 25 |
| University of Texas Health Science Center at Houston | Infant, Small for Gestational Age, Infant, Low Birth Weight, Infant, Newborn | 23 |
| UT MD Anderson | Breast Cancer, AML, Acute Myeloid Leukemia | 22 |
| GSK Investigational Site | Chickenpox, HIV Infections, Gastrointestinal Neoplasms | 18 |
| The University of Texas M.D. Anderson Cancer Center | Advanced Breast Cancer, Breast Cancer, Metastatic Breast Cancer | 18 |
| Prolato Clinical Research Center | Primary Membranous Nephropathy, Active Refractory Rheumatoid Arthritis, Arthritis, Rheumatoid | 16 |
| Houston Methodist West Hospital | Anatomic Stage II Breast Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, AL Amyloidosis | 15 |
| MD Anderson West Houston | Metastatic Malignant Neoplasm in the Brain, Stage IV Lung Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8 | 15 |
| Michael E. DeBakey VA Medical Center | Gulf War Syndrome, Adult Growth Hormone Deficiency, Alzheimer Disease | 14 |
| Memorial Hermann Texas Medical Center | Acute Kidney Injury, Ischemic Stroke, Ovarian Carcinoma | 14 |
Active & Upcoming Studies in Houston (2026)
Recruiting trials in Houston grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (1,184 active studies)
- A Phase 1b/2 Open-label, Dose-ranging Safety and Efficacy Study of Oral Cladribine in Patients With Acute Myeloid Leukemia (AML) · Phase 1, Phase 2 · M.D. Anderson Cancer Center
- Phase 1 Study Of TROP2 CAR/IL-15 TGFBR2 KO NK Cell In Patients With Oral Premalignant Lesions · Phase 1 · M.D. Anderson Cancer Center
Neurology & pain (144 active studies)
- Neuro-Intermuscular Coordination Enhancement (NICE) Rehabilitation Through Human-Machine Interaction in Chronic Stroke · EARLY_Phase 1 · University of Houston
- BreEStim in Managing Neuropathic Pain After Spinal Cord Injury (SCI) · The University of Texas Health Science Center, Houston
Diabetes & metabolic (104 active studies)
- Benefits of Insoles With Real-Time Alert and Foot Self-Care Education · Texas Woman's University
- A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide · Phase 3 · Novo Nordisk A/S
Cardiovascular (98 active studies)
- HiCM-188 Cell Therapy in Adults With Advanced Heart Failure Undergoing Heart Bypass Surgery · Phase 1, Phase 2 · HELP Therapeutics Co., Ltd.
- A Prospective, Randomized Multicenter Clinical Trial of the TricValve® Transcatheter Bicaval Valve System in Subjects With Severe Tricuspid Regurgitation. · P+F Products + Features USA Inc.
Mental health & behavior (81 active studies)
- ACT for Veterans With IBD and Mental Health Challenges · VA Office of Research and Development
- Pilot Randomized Trial of BA-GSH in VA PC-MHI · VA Office of Research and Development
Pediatric (45 active studies)
- Feasibility Trial of the Womb Watch Smartphone App To Assess Fetal Movements · Kenneth Moise MD
- Prospective Observational Study of Outcomes After Gemcitabine, Docetaxel, Melphalan, and Carboplatin With Autologous Stem Cell Transplantation in Pediatric Relapsed/Refractory Germ Cell Tumors · M.D. Anderson Cancer Center
HIV / STI (30 active studies)
- Improving HIV Prevention and Substance Use Post-Sexual Assault Services · The University of Texas Health Science Center, Houston
- A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
Vaccines (26 active studies)
- A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Administered as Intramuscular Injection to Healthy Children 15 Months to 6 Years of Age · Phase 3 · GlaxoSmithKline
- Remdesivir for the Treatment of Upper Respiratory Tract Infection Due to RSV in Immunocompromised Individuals · Phase 2 · Fred Hutchinson Cancer Center
Eye & vision (24 active studies)
- A Comparative, Randomized, Investigator-blind, Active-controlled, Parallel-group, Multicenter, Clinical Endpoint Study · Phase 3 · YS Life Science Co., Ltd.
- A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration · Phase 3 · Amgen
Common conditions studied in Houston
- Breast Cancer (79 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Acute Myeloid Leukemia (56 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Advanced Solid Tumor (53 active studies). Recruiting Advanced Solid Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Ovarian Cancer (48 active studies). Ovarian cancer research examines PARP inhibitors, maintenance therapies, and antibody-drug conjugates for recurrent and platinum-resistant disease.
- Colorectal Cancer (46 active studies). Colorectal cancer trials explore novel chemotherapy combinations, targeted agents, and immunotherapy for microsatellite-instability-high tumors.
- Prostate Cancer (42 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
Leading research sponsors in Houston
- M.D. Anderson Cancer Center
- The University of Texas Health Science Center, Houston
- Baylor College of Medicine
- AstraZeneca
- The Methodist Hospital Research Institute
Local regulations and guidelines
Clinical trials in Texas are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Trials run in Texas must also comply with the Texas Medical Privacy Act (TMPA), which extends federal HIPAA protections to a broader range of entities handling participant data.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Houston. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Houston
Hipa.ai aggregates every recruiting study in Houston from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Houston?
There are approximately 3,031 recruiting clinical trials in Houston, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Houston pay participants?
Most recruiting trials in Houston compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Houston?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Houston?
The most common conditions under active study in Houston include Breast Cancer (79), Acute Myeloid Leukemia (56), Advanced Solid Tumor (53), Ovarian Cancer (48), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Houston?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Houston on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Houston?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Houston?
Recruiting research sites in Houston include MD Anderson Cancer Center, M D Anderson Cancer Center, Baylor College of Medicine, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Houston right now?
The largest active categories in Houston are Cancer & tumors (1,184), Neurology & pain (144), Diabetes & metabolic (104). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.