A Study of Zanzalintinib in Participants With Recurrent or Progressive Meningioma
for Meningioma
Sites in Houston, San Antonio +10 more locations
Sponsor: Exelixis
Sex: All·Age: 18+
Code: NCT07428616·Phase 2·Recruiting·Listed Feb 2026
Clinical Trials at UT MD Anderson Cancer Center
As of September 2026, 64 paid clinical trials are recruiting at UT MD Anderson Cancer Center, located at 1515 HOLCOMBE BLVD UNIT 428, HOUSTON, TX 77030-4028, phone (713) 794-1464 in Houston, Texas. Active studies at this site cover conditions such as Breast Cancer, Acute Myeloid Leukemia and Advanced Solid Tumor. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
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Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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64 clinical trials at UT MD Anderson Cancer Center
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KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIST in 1st Line Setting (SynerGIST-1st Line)
for GIST - Gastrointestinal Stromal Tumor
Sites in Houston +16 more locations
Sponsor: Kumquat Biosciences Inc.
Sex: All·Age: 18+
Code: NCT07406633·Phase 2·Recruiting·Listed Feb 2026
Gene Therapy for HER-Positive Cancer (SENTRY-HER2)
for HER2 Expressing Solid Tumors
Sites in Houston +10 more locations
Sponsor: Vironexis Biotherapeutics Inc.
Sex: All·Age: 18+
Code: NCT07192432·Phase 1, Phase 2·Recruiting·Listed Sep 2025
A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Patients With Invasive Mold Infections.
for Invasive Mold Infections
Sites in Houston, San Antonio +17 more locations
Sponsor: Basilea Pharmaceutica
Sex: All·Age: 18+
Code: NCT06925321·Phase 3·Recruiting·Listed Apr 2025
Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas
for Ewing Sarcoma
Sites in Houston +17 more locations
Sponsor: Inhibrx Biosciences, Inc
Sex: All·Age: 12 - 85
Code: NCT03715933·Phase 1·Recruiting·Listed Oct 2018
Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma
for Glioblastoma, IDH-wildtype
Sites in Houston +6 more locations
Sponsor: Orbus Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT05879367·Phase 1·Recruiting·Listed May 2023
Self-collection for HPV Testing to Improve Cervical Cancer Prevention (SHIP) Trial (LMI-001-A-S04)
for Cervical Carcinoma
Sites in Houston +17 more locations
Sponsor: National Cancer Institute (NCI)
Sex: Female·Age: 25+·Accepts healthy volunteers
Code: NCT07281430·Recruiting·Listed Dec 2025
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
for Breast Cancer
Sites in Houston, Sugar Land +1098 more locations
Sponsor: NRG Oncology
Sex: Female·Age: 18 - 60
Code: NCT05879926·Phase 3·Recruiting·Listed May 2023
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
for Stage III Colon Cancer
Sites in Houston, Sugar Land +913 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
for Anatomic Stage II Breast Cancer AJCC v8
Sites in Houston, Sugar Land +777 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05812807·Phase 3·Recruiting·Listed Apr 2023
Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas
for Intracranial Meningioma
Sites in Houston, Humble +444 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT02523014·Phase 2·Recruiting·Listed Aug 2015
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
for Anatomic Stage I Breast Cancer AJCC v8
Sites in Houston, Sugar Land +591 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT06876714·Phase 3·Recruiting·Listed Mar 2025
Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma
for Smoldering Plasma Cell Myeloma
Drug: Daratumumab
Sites in Houston, Sugar Land +482 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT03937635·Phase 3·Recruiting·Listed May 2019
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
for Anatomic Stage II Breast Cancer AJCC v8
Drug: Durvalumab
Sites in Houston, Sugar Land +533 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06058377·Phase 3·Recruiting·Listed Sep 2023
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
for Childhood Extracranial Germ Cell Tumor
Sites in Houston, Austin +380 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: All ages
Code: NCT03067181·Phase 3·Recruiting·Listed Mar 2017
Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial
for Extensive Stage Lung Small Cell Carcinoma
Drug: Atezolizumab
Sites in Houston, Sugar Land +268 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04402788·Phase 2, Phase 3·Recruiting·Listed May 2020
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
for Locally Advanced Lung Non-Small Cell Carcinoma
Sites in Houston, Sugar Land +444 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT05624996·Phase 3·Recruiting·Listed Nov 2022
Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer
for Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma
Sites in Houston, Sugar Land +324 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT06958328·Phase 3·Recruiting·Listed May 2025
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
for Advanced Malignant Solid Neoplasm
Sites in Houston, Temple +429 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: All ages
Code: NCT05564377·Phase 2·Recruiting·Listed Oct 2022
A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab
for Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8
Drug: Nivolumab
Sites in Houston, Austin +378 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 5 - 60
Code: NCT05675410·Phase 3·Recruiting·Listed Jan 2023
Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma
for Classic Follicular Lymphoma
Drug: Mosunetuzumab
Sites in Houston, San Antonio +251 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06337318·Phase 3·Recruiting·Listed Mar 2024
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer
for Hematopoietic and Lymphatic System Neoplasm
Sites in Houston, San Antonio +189 more locations
Sponsor: Children's Oncology Group
Sex: Female·Age: Up to 39
Code: NCT06513962·Phase 3·Recruiting·Listed Jul 2024
Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain
for Anatomic Stage IV Breast Cancer AJCC v8
Sites in Houston, Sugar Land +255 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT06500455·Phase 3·Recruiting·Listed Jul 2024
Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response
for Prostate Cancer (Adenocarcinoma)
Sites in Houston, Sugar Land +357 more locations
Sponsor: Canadian Cancer Trials Group
Sex: Male·Age: 18+
Code: NCT06592924·Phase 3·Recruiting·Listed Sep 2024
Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas
for Metastatic Dedifferentiated Liposarcoma
Sites in Houston +237 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06422806·Phase 3·Recruiting·Listed May 2024
Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)
for Malignant Female Reproductive System Neoplasm
Sites in Houston, Temple +176 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06126276·Phase 2·Recruiting·Listed Nov 2023
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
for B Acute Lymphoblastic Leukemia
Sites in Houston, Austin +185 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: 365 Days - 25
Code: NCT03959085·Phase 3·Recruiting·Listed May 2019
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations
for Acute Myeloid Leukemia
Sites in Houston, Austin +167 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: Up to 21
Code: NCT04293562·Phase 3·Recruiting·Listed Mar 2020
A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis
for Recurrent Langerhans Cell Histiocytosis
Sites in Houston, Austin +99 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 180 Days - 22
Code: NCT05828069·Phase 2·Recruiting·Listed Apr 2023
Project: Every Child for Younger Patients With Cancer
for Adrenal Gland Pheochromocytoma
Sites in Houston, Austin +225 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: Up to 25
Code: NCT02402244·Recruiting·Listed Mar 2015
A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT
for Anaplastic Kidney Wilms Tumor
Sites in Houston, Austin +170 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: Up to 30
Code: NCT04322318·Phase 2·Recruiting·Listed Mar 2020
Testing the Combination of the Anticancer Drug Durvalumab With Chemotherapy (Gemcitabine and Cisplatin) at Improving Outcomes for High-Risk Resectable Liver Cancer Before Surgery
for Resectable Intrahepatic Cholangiocarcinoma
Drug: Durvalumab
Sites in Houston, Sugar Land +51 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06050252·Phase 2·Recruiting·Listed Sep 2023
A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)
for Malignant Glioma
Drug: Selinexor
Sites in Houston, Austin +104 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 12 Months - 21
Code: NCT05099003·Phase 1, Phase 2·Recruiting·Listed Oct 2021
Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer
for Buccal Mucosa Squamous Cell Carcinoma
Sites in Houston, Sugar Land +85 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT04333537·Phase 2, Phase 3·Recruiting·Listed Apr 2020
A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma
for Low Grade Astrocytoma
Drug: Selumetinib
Sites in Houston, Austin +115 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 2 - 21
Code: NCT04166409·Phase 3·Recruiting·Listed Nov 2019
A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)
for Stage II Nasopharyngeal Carcinoma AJCC v8
Drug: Nivolumab
Sites in Houston, Austin +73 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: Up to 21
Code: NCT06064097·Phase 2·Recruiting·Listed Oct 2023
The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study
for Acute Lymphoblastic Leukemia
Sites in Houston, Austin +154 more locations
Sponsor: PedAL BCU, LLC
Sex: All·Age: Up to 22
Code: NCT04726241·Phase 1, Phase 2·Recruiting·Listed Jan 2021
Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma
for Metastatic Malignant Neoplasm in the Lung
Sites in Houston, Austin +200 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: Up to 50
Code: NCT05235165·Phase 3·Recruiting·Listed Feb 2022
A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma
for Basal Ganglia Germinoma
Sites in Houston, Austin +93 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: 3 - 29
Code: NCT06368817·Phase 2·Recruiting·Listed Apr 2024
Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma
for Ganglioneuroblastoma, Nodular
Sites in Houston, Austin +152 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: Up to 30
Code: NCT06172296·Phase 3·Recruiting·Listed Dec 2023
Common conditions studied in Houston
- Breast Cancer (76 active studies)
- Acute Myeloid Leukemia (52 active studies)
- Advanced Solid Tumor (52 active studies)
- Colorectal Cancer (46 active studies)
- Ovarian Cancer (46 active studies)
- Prostate Cancer (43 active studies)
Leading research sponsors in Houston
- M.D. Anderson Cancer Center
- The University of Texas Health Science Center, Houston
- Baylor College of Medicine
- AstraZeneca
- The Methodist Hospital Research Institute
Frequently asked questions
How many paid clinical trials are currently recruiting in Houston?
There are approximately 3,045 recruiting clinical trials in Houston, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Houston pay participants?
Most recruiting trials in Houston compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Houston?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Houston?
The most common conditions under active study in Houston include Breast Cancer (76), Acute Myeloid Leukemia (52), Advanced Solid Tumor (52), Colorectal Cancer (46), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Houston?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Houston on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Houston?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Houston?
Recruiting research sites in Houston include MD Anderson Cancer Center, M D Anderson Cancer Center, Baylor College of Medicine, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Houston right now?
The largest active categories in Houston are Cancer & tumors (1,171), Neurology & pain (140), Diabetes & metabolic (105). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of UT MD Anderson Cancer Center?
UT MD Anderson Cancer Center is located at 1515 HOLCOMBE BLVD UNIT 428, HOUSTON, TX 77030-4028. Use the Google Maps link in the intro above to get directions.
How do I contact UT MD Anderson Cancer Center?
You can reach UT MD Anderson Cancer Center by phone at (713) 794-1464. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.
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