Paid Clinical Trials in Louisville, KY
As of June 2026, 548 paid clinical trials are recruiting in Louisville, Kentucky. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Louisville offers studies at sites including University of Louisville for conditions such as Heart Failure, Acute Myeloid Leukemia, Breast Cancer, Head and Neck Squamous Cell Carcinoma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Louisville
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·Clear filters·↓ Download CSVAbout research studies in Louisville
Louisville has approximately 548 recruiting research studies across a wide range of therapeutic areas. Kentucky hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.
Top Research Study Locations in Louisville
Researchers run research studies in Louisville, KY at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Louisville | Gastroparesis, Gastroparesis Nondiabetic, Stroke | 66 |
| UofL Health Medical Center Northeast | Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Metastatic Malignant Neoplasm in the Brain | 53 |
| Norton Cancer Institute | Multiple Myeloma, Ovarian Cancer, Advanced Solid Tumors | 39 |
| The James Graham Brown Cancer Center at University of Louisville | Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm | 39 |
| Norton Children's Hospital | Acute Myeloid Leukemia, Malignant Solid Neoplasm, B Acute Lymphoblastic Leukemia | 32 |
| Baptist Health Louisville | Breast Cancer, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 26 |
| Jewish Hospital | Stage IIIB Lung Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8, Adenocarcinoma of the Colon | 21 |
| Saints Mary and Elizabeth Hospital | Stage IIIB Lung Cancer AJCC v8, Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum | 20 |
| University of Louisville Hospital | Acute Decompensated Heart Failure, Alcohol Use Disorder, Alcohol-associated Liver Disease | 13 |
| Norton Healthcare | Atrial Arrhythmia, Atrial Tachycardia, Autoimmune Diseases | 11 |
| Norton Children's Research Institute/Affiliated with University of Louisville School of Medicine | Neuroblastoma, Ewing Sarcoma, Liposarcoma | 7 |
| Robley Rex VA Medical Center | Burn Pit Exposure, Diabetes Mellitus, Type 1, Environmental Exposures | 7 |
| Gastroenterology Health Partners | Obesity or Overweight, Ulcerative Colitis, C. Diff Infection | 6 |
| Norton Cancer Institute - Downtown | Breast Cancer, Carcinoma, Cervical Cancer | 6 |
| Norton Brownsboro Hospital and Medical Campus | Anatomic Stage IV Breast Cancer AJCC v8, Extensive Stage Lung Small Cell Carcinoma, Intracranial Meningioma | 5 |
| Norton Cancer Institute, St. Matthews Campus | Acute Myeloid Leukemia, Acute Myeloid Leukemias, CLL (Chronic Lymphocytic Leukemia) | 5 |
| Norton Hospital | Pulmonary Hypertension, Cardiovascular Diseases, Cervical Cancer | 5 |
| Norton Women's and Children's Hospital | Cervical Cancer, Fallopian Tube Neoplasms, Multiple Myeloma | 5 |
| University of Louisville Health | Brain Injuries, Diffuse Large B Cell Lymphoma (DLBCL), Diffuse Large B Cell Lymphoma Refractory | 5 |
| Monroe Biomedical Research - Louisville | Obesity, Overweight, Osteoarthritis | 4 |
| Norton Hospital Pavilion and Medical Campus | Endometrial Cancer, Extensive Stage Lung Small Cell Carcinoma, Ovarian Carcinoma | 4 |
| UofL Health Brown Cancer Center | Breast Cancer, Leukemia, Myeloid, Acute, Locally Advanced or Metastatic Castration-resistant Prostate Cancer | 4 |
| Frazier Rehabilitation and Neuroscience Institute | Spinal Cord Injuries, Autonomic Dysreflexia, Breathing Exercises | 3 |
| GSK Investigational Site | Chickenpox, Colonic Neoplasms, HIV Infections | 3 |
| James Graham Brown Cancer Center | Infusion Reactions, Metastatic Breast Cancer, Non Small Cell Lung Cancer | 3 |
Active & Upcoming Studies in Louisville (2026)
Recruiting trials in Louisville grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (216 active studies)
- A Study to Select a Dose Regimen (Part A) and to Investigate Overall Survival (Part B) With Nanvuranlat Compared With Physician's Best Choice in Participants Aged 18 Years or Older With Biliary Tract Cancer · Phase 3 · J-Pharma Co., Ltd.
- A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma · Phase 2 · Regeneron Pharmaceuticals
Cardiovascular (45 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH) · Phase 3 · Inhibikase Therapeutics
Diabetes & metabolic (27 active studies)
- A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight · Phase 2 · Eli Lilly and Company
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
Neurology & pain (20 active studies)
- Gastric Electrical Stimulation for Abdominal Pain in Patients With Gastroparesis · University of Louisville
- Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis · Phase 3 · Bristol-Myers Squibb
Vaccines (5 active studies)
- A Study to Evaluate the Safety and Efficacy of CD388 for Prevention of Influenza · Phase 3 · Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
- Osteopathic Manipulative Therapy Effects on Post-Acute Sequelae of COVID-19 (PASC) or Long COVID · University of Louisville
Pediatric (4 active studies)
HIV / STI (3 active studies)
- A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study) · Phase 2 · ViiV Healthcare
- Long-Acting Injectable HIV PrEP PROs · Anupama Raghuram MD
Eye & vision (3 active studies)
- CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME · Phase 3 · EyePoint Pharmaceuticals, Inc.
- A Clinical Study to Evaluate the Effect and Side Effect of a New Artificial Tear Formulation (ABBV-444) Compared to Refresh Optive Unit Dose in Adult Participants With Dry Eye Disease · Phase 3 · AbbVie
Mental health & behavior (1 active study)
- Harm Reduction for Smokers With Mental Illness · Dartmouth-Hitchcock Medical Center
Common conditions studied in Louisville
- Heart Failure (12 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Acute Myeloid Leukemia (10 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Breast Cancer (9 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Head and Neck Squamous Cell Carcinoma (8 active studies). Recruiting Head and Neck Squamous Cell Carcinoma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Obesity (8 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
- Spinal Cord Injuries (8 active studies). Recruiting Spinal Cord Injuries studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Louisville
- University of Louisville
- National Cancer Institute (NCI)
- AstraZeneca
- Merck Sharp & Dohme LLC
- Children's Oncology Group
Local regulations and guidelines
Clinical trials in Kentucky are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Kentucky research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Louisville. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Louisville
Hipa.ai aggregates every recruiting study in Louisville from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Louisville?
There are approximately 548 recruiting clinical trials in Louisville, Kentucky listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Louisville pay participants?
Most recruiting trials in Louisville compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Louisville?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Louisville?
The most common conditions under active study in Louisville include Heart Failure (12), Acute Myeloid Leukemia (10), Breast Cancer (9), Head and Neck Squamous Cell Carcinoma (8), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Louisville?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Louisville on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Louisville?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Louisville?
Recruiting research sites in Louisville include University of Louisville, UofL Health Medical Center Northeast, Norton Cancer Institute, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Louisville right now?
The largest active categories in Louisville are Cancer & tumors (216), Cardiovascular (45), Diabetes & metabolic (27). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.