Oncology Clinical Trials in Minneapolis, MN
As of August 2026, 159 paid clinical trials are recruiting for Oncology in Minneapolis, Minnesota. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Minneapolis
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
160 clinical trials for Oncology
·Clear filters·A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)
This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.
A Study of Sigvotatug Vedotin in Advanced Solid Tumors
A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)
FOG-001 in Locally Advanced or Metastatic Solid Tumors
A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer
A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.
Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)
Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer
A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis
Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)
Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1
A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.
A Study Comparing JNJ-79635322 and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma
A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
Top Research Study Locations in Minneapolis
Researchers run research studies in Minneapolis, MN at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Minnesota | Parkinson Disease, Depression, Amyotrophic Lateral Sclerosis | 300 |
| Abbott-Northwestern Hospital | Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 83 |
| Hennepin County Medical Center | Malignant Solid Neoplasm, Stage IV Renal Cell Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8 | 69 |
| University of Minnesota/Masonic Cancer Center | Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia, Malignant Solid Neoplasm | 36 |
| Minneapolis Heart Institute Foundation | Coronary Artery Disease, Cardiovascular Diseases, Heart Failure | 31 |
| Minneapolis VA Health Care System, Minneapolis, MN | Amputation, Bipolar Disorder, Spinal Cord Diseases | 29 |
| Children's Hospitals and Clinics of Minnesota - Minneapolis | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 25 |
| Health Partners Inc | Stage IVB Prostate Cancer AJCC v8, Ovarian Carcinoma, Acral Lentiginous Melanoma | 20 |
| University of Minnesota Medical Center | ADA SCID, Advanced Melanoma, Aortic Stenosis | 17 |
| Masonic Cancer Center | Acute Myeloid Leukemia, Smoking Cessation, Acute Lymphoblastic Leukemia | 15 |
| Minneapolis Heart Institute | Coronary Artery Disease, Cardiovascular Diseases, Heart Diseases | 15 |
| Minneapolis VA Medical Center | Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8 | 14 |
| Abbott Northwestern Hospital | AMI, Acute Stroke, Aneurysm Cerebral | 10 |
| M Health Fairview University of Minnesota Medical Center | Ischemic Stroke, Adamantinomatous Craniopharyngioma, Atrial Fibrillation | 8 |
| Minneapolis VA Health Care System | Heart Failure, Aging Related Cognitive Decline, Chronic Obstructive Pulmonary Disease | 8 |
| University of Minnesota Masonic Children's Hospital | Fabry Disease, High-Risk Neuroblastoma, Hypochondroplasia | 8 |
| University of Minnesota Medical School | Niemann-Pick Type C Disease, Advanced Solid Tumor, Alopecia | 8 |
| Children's Hospitals and Clinics of Minnesota | Cystic Fibrosis, B-cell Acute Lymphoblastic Leukemia, Caregiver Burden | 8 |
| Allina Health Cancer Institute - Abbott Northwestern Hospital | Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Advanced Hepatocellular Carcinoma | 7 |
| Children's Minnesota | Ciliary Body Medulloepithelioma, Craniopharyngioma, Craniopharyngioma, Child | 7 |
| Masonic Cancer Center at University of Minnesota | Myelodysplastic Syndromes, Acute Leukemia, Acute Myeloid Leukemia | 7 |
| Masonic Cancer Center, University of Minnesota | Adenocarcinoma of Lung, Alcohol-Related Carcinoma, Epithelial Ovarian Cancer | 7 |
| Children's Hospital and Clinics of Minnesota | Neuroblastoma, ALL, AML | 6 |
| Hennepin Healthcare | Acute Respiratory Failure, Awareness, Carcinoma, Hepatocellular | 6 |
| International Diabetes Center | Obesity, Type 1 Diabetes Mellitus, Type 2 Diabetes | 6 |
Active & Upcoming Studies in Minneapolis (2026)
Recruiting trials in Minneapolis grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (244 active studies)
- Signatera Assessment in Early-Stage Endometrial Cancer · Natera, Inc.
- ICARE-LCS QUERI Partnered Evaluation Initiative: Integrating Comprehensive Tobacco Treatment to Enhance Lung Cancer Screening · VA Office of Research and Development
Cardiovascular (72 active studies)
- Validation and Feasibility of Noninvasive Oxygen Delivery Index Monitoring in Cardiac Surgery Patients · University of Minnesota
- Microbiota Transplant With Antibiotic Preconditioning and Fiber Supplementation in PAH. · Phase 1 · University of Minnesota
Neurology & pain (54 active studies)
- Simultaneous Engagement of Networks for Alleviating Pain (SENAP) · Phase 1 · University of Minnesota
- Myofunctional Therapy for Obstructive Sleep Apnea · University of Minnesota
Diabetes & metabolic (44 active studies)
- GLP-1 Plus Lifestyle for Overall Wellness: Find Your Way Forward · Phase 4 · University of Minnesota
- Mitigating DKA in Type 1 Diabetes for Safe Use of SGLT Inhibitors Using Dual Continuous Ketone and Glucose Monitoring. · Phase 2 · HealthPartners Institute
Mental health & behavior (31 active studies)
- ICARE-LCS QUERI Partnered Evaluation Initiative: Integrating Comprehensive Tobacco Treatment to Enhance Lung Cancer Screening · VA Office of Research and Development
- NEURO-COGS: Neurometabolic Mechanisms of Cognitive Training in Schizophrenia · University of Minnesota
Pediatric (14 active studies)
- Magnesium Sulfate in Pediatric Burn Dressing Changes · Phase 1 · Hennepin Healthcare Research Institute
- Optimizing Pain Treatment in Children On Mechanical Ventilation · Phase 3 · Weill Medical College of Cornell University
HIV / STI (7 active studies)
- Combating HIV Stigma in Healthcare Settings: A Standardized Patient Approach · University of Minnesota
- Optimizing Medications and Lung Health in People With HIV Through Pharmacist-led Proactive E-Consults · Seattle Institute for Biomedical and Clinical Research
Eye & vision (5 active studies)
- Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants · Phase 4 · Neurotech Pharmaceuticals
- A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma · Phase 3 · AbbVie
Vaccines (2 active studies)
- Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID · Phase 3 · Wes Ely
- EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease · Phase 3 · Pfizer
Common conditions studied in Minneapolis
- Heart Failure (17 active studies)
- Acute Myeloid Leukemia (16 active studies)
- Ovarian Cancer (13 active studies)
- Breast Cancer (12 active studies)
- Coronary Artery Disease (11 active studies)
- Endometrial Cancer (11 active studies)
Leading research sponsors in Minneapolis
- University of Minnesota
- National Cancer Institute (NCI)
- Masonic Cancer Center, University of Minnesota
- VA Office of Research and Development
- Children's Oncology Group
Frequently asked questions
How many paid clinical trials are currently recruiting in Minneapolis?
There are approximately 907 recruiting clinical trials in Minneapolis, Minnesota listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Minneapolis pay participants?
Most recruiting trials in Minneapolis compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Minneapolis?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Minneapolis?
The most common conditions under active study in Minneapolis include Heart Failure (17), Acute Myeloid Leukemia (16), Ovarian Cancer (13), Breast Cancer (12), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Minneapolis?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Minneapolis on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Minneapolis?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Minneapolis?
Recruiting research sites in Minneapolis include University of Minnesota, Abbott-Northwestern Hospital, Hennepin County Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Minneapolis right now?
The largest active categories in Minneapolis are Cancer & tumors (244), Cardiovascular (72), Neurology & pain (54). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.