Paid Clinical Trials in Naples, FL
As of July 2026, 94 paid clinical trials are recruiting in Naples, Florida. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Naples offers studies at sites including Aqualane Clinical Research for conditions such as Obesity, Overweight, Persistent Atrial Fibrillation, Alzheimer Disease. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Naples
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Researchers run research studies in Naples, FL at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Aqualane Clinical Research | Alzheimer Disease, CIDP, Chronic Inflammatory Demyelinating Polyneuropathy | 14 |
| NCH Rooney Heart Institute | AMI Cardiogenic Shock, Aortic Valve Disease Mixed, Aortic Valve Regurgitation | 5 |
| Advanced Research for Health Improvement, LLC | Atherosclerotic Cardiovascular Disease (ASCVD), Cardiovascular Diseases, Diabetes Mellitus, Type 2 | 4 |
| Essence MD Research | Obesity, Overweight, Obstructive Sleep Apnoea | 4 |
| Florida Cancer Specialists | Advanced Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC) | 4 |
| Naples Community Hospital | Atrial Fibrillation, Heart Failure, PFO - Patent Foramen Ovale | 4 |
| GI PROS Research | Metabolic Dysfunction-Associated Steatotic Liver Disease, Ulcerative Colitis, C. Diff Infection | 4 |
| CLA Research | Bipolar Disorder, Depressive Disorder, Major, Schizophrenia | 3 |
| GSK Investigational Site | Bronchiectasis, Lung Diseases, Interstitial, Pulmonary Disease, Chronic Obstructive | 3 |
| Naples Comprehensive Health | Acute DVT of Lower Extremity, Acute Limb Ischemia, Arterial Embolism and Thrombosis | 3 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, MASH With Fibrosis, NASH - Nonalcoholic Steatohepatitis | 2 |
| N/A - Remote Study | Ankyloglossia, Behavior Change Interventions, Habits | 2 |
| NCH Healthcare | AV Node Disease, Atrial Fibrillation, Pacemaker Implantation | 2 |
| NCH Research Institute | Heart Failure, Interstitial Lung Disease, Pulmonary Hypertension | 2 |
| Praxis Research Site | Epilepsy, Tonic-Clonic, Focal Epilepsy, Focal Seizure | 2 |
| Advanced Res for Health Improve | Obesity, Osteoarthritis, Knee, Overweight | 1 |
| Advanced Research for Health Improvement LLC | Cardiovascular Disease and Lipoprotein(a) | 1 |
| Aesthetic Surgery Center | Reconstructive Surgical Procedures | 1 |
| Altimmune Clinical Study Site | Alcohol Liver Disease | 1 |
| Bascom Palmer Eye Institute | Age-related Macular Degeneration (AMD), Geographic Atrophy (GA) | 1 |
| Clinical Study Site | Down Syndrome-Associated Alzheimer's Disease (DS-AD) | 1 |
| Clinical Trial Site | Transthyretin Amyloidosis With Cardiomyopathy | 1 |
| GI PROS, Inc. | Crohn's Disease | 1 |
| Hospital for Special Surgery at Naples Comprehensive Health (HSS at NCH) | Meniscus Tear | 1 |
| Local Institution - 007-922-F | Advanced Non-Small Cell Lung Cancer, Metastatic Non-Small Cell Lung Cancer | 1 |
Active & Upcoming Studies in Naples (2026)
Recruiting trials in Naples grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Neurology & pain (17 active studies)
- AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea · Phase 3 · Novo Nordisk A/S
- AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea · Phase 3 · Novo Nordisk A/S
Cardiovascular (14 active studies)
- Conquer-AF Protocol for Redo Ablation Procedures in Recurrent Paroxysmal and Persistent Atrial Fibrillation Using the Sphere-9 Catheter and Affera Ablation System (Conquer-AF) · Medtronic Cardiac Ablation Solutions
- Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD) · Phase 3 · Insmed Incorporated
Diabetes & metabolic (7 active studies)
- A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide · Phase 3 · Novo Nordisk A/S
- AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea · Phase 3 · Novo Nordisk A/S
Cancer & tumors (4 active studies)
- Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer · Phase 3 · Pfizer
- Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer · Phase 4 · Pfizer
Mental health & behavior (3 active studies)
- A Study of Brenipatide in Adult Participants With Schizophrenia · Phase 2 · Eli Lilly and Company
- A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder · Phase 3 · Cybin IRL Limited
Eye & vision (2 active studies)
- A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration · Phase 3 · Amgen
- A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy · Phase 3 · Regeneron Pharmaceuticals
Pediatric (1 active study)
- Randomized Study in Children and Adolescents With Migraine: Acute Treatment · Phase 3 · Pfizer
Common conditions studied in Naples
- Obesity (4 active studies)
- Overweight (4 active studies)
- Persistent Atrial Fibrillation (4 active studies)
- Alzheimer Disease (3 active studies)
- Heart Failure (3 active studies)
- Advanced Non-Small Cell Lung Cancer (2 active studies)
Leading research sponsors in Naples
- Eli Lilly and Company
- AstraZeneca
- Boehringer Ingelheim
- Novo Nordisk A/S
- Pfizer
Frequently asked questions
How many paid clinical trials are currently recruiting in Naples?
There are approximately 94 recruiting clinical trials in Naples, Florida listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Naples pay participants?
Most recruiting trials in Naples compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Naples?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Naples?
The most common conditions under active study in Naples include Obesity (4), Overweight (4), Persistent Atrial Fibrillation (4), Alzheimer Disease (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Naples?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Naples on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Naples?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Naples?
Recruiting research sites in Naples include Aqualane Clinical Research, NCH Rooney Heart Institute, Advanced Research for Health Improvement, LLC, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Naples right now?
The largest active categories in Naples are Neurology & pain (17), Cardiovascular (14), Diabetes & metabolic (7). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.