Solid tumor Clinical Trials in Oklahoma City, OK
As of September 2026, 30 paid clinical trials are recruiting for Solid tumor in Oklahoma City, Oklahoma. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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30 clinical trials for Solid tumor
·Clear filters·A Study of JZP815 Oral Capsules in Adult Participants With Advanced or Metastatic Solid Tumors Harboring Mitogen Activated Protein Kinase (MAPK) Pathway Alterations to Investigate the Safety, Dosing, and Antitumor Activity of JZP815
QTX3034 in Patients With KRAS G12D Mutation
A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors
A Study of CUSP06 in Patients With Platinum-Refractory/Resistant Ovarian Cancer and Other Advanced Solid Tumors
A Clinical Study of YL205 in Patients With Advanced Solid Tumors
Study of SGR-3515 In Participants With Advanced Solid Tumors.
First-in-human Study of CRB-601-01 to Treat Patients With Advanced Solid Tumor.
Study of AVZO-021 in Patients With Advanced Solid Tumors
FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors
A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer
Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain
Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)
Project: Every Child for Younger Patients With Cancer
The Vanguard Study: Testing a New Way to Screen for Cancer
Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes
Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers
Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors
Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness
Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)
Testing A New Anti-cancer Drug Combination, Entinostat and ZEN003694, for Advanced and Refractory Solid Tumors
A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients
A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study
A Phase 2 Study of Avutometinib (VS-6766) Plus Defactinib
Collection and Storage of Tissue and Blood Samples From Patients With Cancer
A Phase 1/2 Study of BHV-1510 (Previously PBI-410) in Advanced Solid Tumors
Top Research Study Locations in Oklahoma City
Researchers run research studies in Oklahoma City, OK at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Oklahoma Health Sciences Center | Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8 | 185 |
| Mercy Hospital Oklahoma City | Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8, Advanced Lung Non-Small Cell Carcinoma | 47 |
| University of Oklahoma | Endometrial Cancer, Colorectal Cancer, Ovarian Cancer | 26 |
| OU Health Stephenson Cancer Center | Ovarian Cancer, AML With Mutated NPM1, Acute Myeloid Leukemia | 20 |
| Stephenson Cancer Center | Cervical Cancer, Endometrial Cancer, Ovarian Cancer | 13 |
| The University of Oklahoma Health Sciences Center | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 11 |
| Hightower Clinical | Acute Migraine, Antineutrophil Cytoplasmic Antibody-associated Vasculitis, Cancer | 10 |
| Oklahoma Medical Research Foundation | Systemic Lupus Erythematosus, Aging, Multiple Sclerosis | 10 |
| Sooner Clinical Research | Generalized Anxiety Disorder, Major Depressive Disorder, Autism Spectrum Disorder | 8 |
| TSET Health Promotion Research Center | CRC (Colorectal Cancer), CRC Screening, Smoking Cessation | 8 |
| Oklahoma Heart Hospital | Acute Decompensated Heart Failure, Aortic Stenosis, CHF | 7 |
| Lynn Health Science Institute | Obesity or Overweight, Acne Vulgaris, Hypercholesterolemia | 6 |
| University of Oklahoma Health Campus | Amyloid Pathology, Brain Activity, Brain Aging | 5 |
| University of Oklahoma Health Science Center | Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL), Autoimmune Diseases | 5 |
| Integris Baptist Medical Center | Cardiovascular Diseases, Pulmonary Hypertension, Connective Tissue Diseases | 5 |
| Oklahoma Children's Hospital | Anesthesia, Asthma Attack, Asthma in Children | 4 |
| Oklahoma Proton Center | Breast Cancer, Breast Neoplasm, Breast Tumor | 4 |
| Unity Clinical Research | Atopic Dermatitis, Chronic Spontaneous Urticaria (CSU), Hidradenitis Suppurativa | 4 |
| University of Oklahoma Health Sciences | Acute Respiratory Distress Syndrome, Cancer Survivorship, Chemotherapy Side Effects | 4 |
| Digestive Disease Specialists Inc | Crohn Disease, Colitis, Ulcerative | 3 |
| GSK Investigational Site | Asthma, Alzheimer's Disease | 3 |
| Integris Cancer Institute of Oklahoma | Stage IIIB Lung Cancer AJCC v8, Advanced Lung Non-Squamous Non-Small Cell Carcinoma, Lung Non-Small Cell Carcinoma | 3 |
| Integris Southwest Medical Center | Previously Treated Non-Small Cell Lung Cancer, Recurrent Lung Non-Small Cell Carcinoma, Stage III Colon Cancer | 3 |
| OU Health University of Oklahoma Medical Center | Acquired Antithrombin Deficiency, Carcinoma, Non-Small Cell Lung, Cutaneous Squamous Cell Cancer | 3 |
| Oklahoma University Health Sciences Center | Advanced Solid Tumors, Colorectal Cancer, Inflammation | 3 |
Active & Upcoming Studies in Oklahoma City (2026)
Recruiting trials in Oklahoma City grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (249 active studies)
- Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial · Phase 3 · National Cancer Institute (NCI)
- Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatment Regimen (Cytarabine and Daunorubicin, "7+3") for Core Binding Factor Acute Myeloid Leukemia (CBF-AML) to Improve Response (A MYELOMATCH Treatment Trial) · Phase 2 · National Cancer Institute (NCI)
Cardiovascular (39 active studies)
Diabetes & metabolic (27 active studies)
- Disulfiram in Rheumatoid Arthritis · Phase 2 · University of Oklahoma
- Impact of Chia Seeds on Human Breast Milk Composition · University of Oklahoma
Mental health & behavior (23 active studies)
- Relapse Prevention Trial Evaluating KarXT Treatment in Schizophrenia · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- Trial of Varenicline With Nicotine Lozenges and a Smartphone Medication Adherence Intervention for Smoking Cessation · Phase 2 · University of Oklahoma
Neurology & pain (23 active studies)
- A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine · Phase 3 · Kallyope Inc.
- A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine · Phase 3 · Kallyope Inc.
Pediatric (6 active studies)
- Supraglottic Airway for Resuscitation Trial · Children's Hospital of Philadelphia
- iAmHealthy Clinical Practice Guideline (CPG) · University of Kansas Medical Center
Eye & vision (3 active studies)
- Phase 2/Phase 3 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant · Phase 2, Phase 3 · Glaukos Corporation
- A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma · Phase 3 · AbbVie
Vaccines (2 active studies)
- Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children · Phase 3 · University of Alabama at Birmingham
- Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study · Phase 3 · Ansun Biopharma, Inc.
Common conditions studied in Oklahoma City
- Endometrial Cancer (17 active studies)
- Ovarian Cancer (14 active studies)
- Acute Myeloid Leukemia (13 active studies)
- Malignant Solid Neoplasm (10 active studies)
- Breast Cancer (9 active studies)
- Major Depressive Disorder (9 active studies)
Leading research sponsors in Oklahoma City
- University of Oklahoma
- National Cancer Institute (NCI)
- Alliance for Clinical Trials in Oncology
- SWOG Cancer Research Network
- Children's Oncology Group
Frequently asked questions
How many paid clinical trials are currently recruiting in Oklahoma City?
There are approximately 594 recruiting clinical trials in Oklahoma City, Oklahoma listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Oklahoma City pay participants?
Most recruiting trials in Oklahoma City compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Oklahoma City?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Oklahoma City?
The most common conditions under active study in Oklahoma City include Endometrial Cancer (17), Ovarian Cancer (14), Acute Myeloid Leukemia (13), Malignant Solid Neoplasm (10), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Oklahoma City?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Oklahoma City on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Oklahoma City?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Oklahoma City?
Recruiting research sites in Oklahoma City include University of Oklahoma Health Sciences Center, Mercy Hospital Oklahoma City, University of Oklahoma, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Oklahoma City right now?
The largest active categories in Oklahoma City are Cancer & tumors (249), Cardiovascular (39), Diabetes & metabolic (27). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.