Oncology Clinical Trials in Omaha, NE
As of August 2026, 150 paid clinical trials are recruiting for Oncology in Omaha, Nebraska. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Omaha
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
151 clinical trials for Oncology
·Clear filters·Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy
A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.
A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)
A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma
A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)
A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)
Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma
A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma
Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC
A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer
Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy
A Study to Learn About the Effects of the Combination of Elranatamab (PF-06863135) and Iberdomide in Patients With Relapsed or Refractory Multiple Myeloma (MagnetisMM-30)
Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy
TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers
A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer
GEMINI-NSCLC: NSCLC Biomarker Study
Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
Top Research Study Locations in Omaha
Researchers run research studies in Omaha, NE at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Nebraska Medical Center | Acute Myeloid Leukemia, Multiple Myeloma, Breast Cancer | 219 |
| Nebraska Cancer Specialists | Breast Cancer, Colorectal Cancer, Non-Small Cell Lung Cancer | 41 |
| Nebraska Medicine-Village Pointe | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8 | 39 |
| Children's Hospital and Medical Center of Omaha | B Acute Lymphoblastic Leukemia, Malignant Solid Neoplasm, Acute Myeloid Leukemia | 28 |
| Nebraska Methodist Hospital | Endometrial Clear Cell Adenocarcinoma, Endometrial Dedifferentiated Carcinoma, Endometrial Endometrioid Adenocarcinoma | 28 |
| Alegent Health Bergan Mercy Medical Center | Malignant Solid Neoplasm, Plasma Cell Myeloma, Prostate Adenocarcinoma | 22 |
| Alegent Health Immanuel Medical Center | Malignant Solid Neoplasm, Plasma Cell Myeloma, RISS Stage I Plasma Cell Myeloma | 20 |
| Alegent Health Lakeside Hospital | Malignant Solid Neoplasm, Plasma Cell Myeloma, RISS Stage I Plasma Cell Myeloma | 20 |
| Nebraska Cancer Specialists/Oncology Hematology West PC - MECC | Ovarian Carcinoma, Stage II Lip and Oral Cavity Cancer AJCC v8, Stage III Laryngeal Cancer AJCC v8 | 14 |
| Omaha VA Nebraska-Western Iowa Health Care System, Omaha, NE | Chronic Obstructive Pulmonary Disease, Adult Growth Hormone Deficiency, Alcohol Use Disorder (AUD) | 13 |
| University of Nebraska | Adenocarcinoma, Pancreatic Ductal, Adenovirus Infections, Brain Tumor | 12 |
| Creighton University Medical Center | Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 10 |
| Creighton University | Age-associated Muscle Loss, Anxiety and Mood Disorders, Bilateral Vestibular Hypofunction | 8 |
| Boys Town National Research Hospital | Developmental Language Disorder, Autism, Autism Spectrum Disorder | 7 |
| Nebraska Medicine | Cachexia, Choline Deficiency, Engagement | 7 |
| Children's Nebraska | Acute Kidney Injury, Bronchiolitis Acute, Chronic Kidney Disease(CKD) | 6 |
| Oncology Hematology West P.C. dba Nebraska Cancer Specialists | Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC), Head and Neck Squamous Cell Carcinoma (HNSCC) | 6 |
| GSK Investigational Site | Colonic Neoplasms, Gastrointestinal Neoplasms, Gastrointestinal Stromal Neoplasms | 5 |
| Nebraska Medical Center | Atrial Fibrillation, Cardiac Arrest, Cardiopulmonary Arrest | 5 |
| Unversity of Nebraska Medical Center | Chronic Pancreatitis, Diabetes Mellitus, Type 2, Genetic Predisposition to Disease | 4 |
| Oncology Hematology West, PC dba Nebraska Cancer Specialists | Follicular Lymphoma (FL), Metastatic Castration Resistant Prostate Cancer (mCRPC), Refractory Diffuse Large B-cell Lymphoma | 4 |
| Children's Hospital & Medical Center | Acute Treatment of Migraine, Pediatric Migraine | 3 |
| Fred & Pamela Buffet Cancer Center | Allogeneic Hematopoietic Stem Cell Transplant (Allo-HSCT), Diffuse Large B-Cell Lymphoma, Prostate Adenocarcinoma | 3 |
| Skin Specialists, PC dba Schlessinger MD | Atopic Dermatitis, Hidradenitis Suppurativa, Severe Alopecia Areata | 3 |
| Vance Thompson Vision | Age-Related Macular Degeneration, Astigmatism, Geographic Atrophy | 3 |
Active & Upcoming Studies in Omaha (2026)
Recruiting trials in Omaha grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (257 active studies)
- Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatment Regimen (Cytarabine and Daunorubicin, "7+3") for Core Binding Factor Acute Myeloid Leukemia (CBF-AML) to Improve Response (A MYELOMATCH Treatment Trial) · Phase 2 · National Cancer Institute (NCI)
- Abi/Pred + ADT vs ADT in PSMA-Positive, Conventionally Node-Negative Prostate Cancer · Phase 2 · University of Nebraska
Cardiovascular (38 active studies)
- Xenon for Neuroprotection During Post-Cardiac Arrest Syndrome in Comatose Survivors of an Out of Hospital Cardiac Arrest · Phase 3 · Invero Pharma, Inc.
- Butyric Acid Supplementation for Gut Improvement After Cardiac Surgery in Kids · Phase 1, Phase 2 · University of Nebraska
Diabetes & metabolic (17 active studies)
- A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight · Phase 3 · AstraZeneca
- A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2) · Phase 3 · Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Neurology & pain (15 active studies)
- Clinical Validation of Self-Pacing Algorithms on Step Length Symmetry in Hemiplegic Populations · Quality Living, Inc.
- The Impact of Enhanced Music & Natural Visuals on Emotional Health · soundBrilliance LLC
Pediatric (8 active studies)
- Evaluating the Effects of an Electrical Stimulator on Improving the Walking Ability of Children With Cerebral Palsy · University of Nebraska
- iAmHealthy Clinical Practice Guideline (CPG) · University of Kansas Medical Center
Vaccines (6 active studies)
- A Study to Characterize the Safety and Immunogenicity of AZD6489 in Participants 60 Years of Age and Older (ARIES) · Phase 1, Phase 2 · AstraZeneca
- Heat thErapy And mobiLity in COVID-19 Survivors · University of Nebraska
Eye & vision (6 active studies)
- A Multicenter, Open-Label Study to Evaluate Perioperative Treatment of Dry Eye With Miebo® in Subjects Undergoing LASIK · Phase 4 · Vance Thompson Vision
- The Safety and Efficacy of Direct SLT in Pseudoexfoliation Glaucoma · Vance Thompson Vision
Mental health & behavior (4 active studies)
- The Impact of Enhanced Music & Natural Visuals on Emotional Health · soundBrilliance LLC
- Evaluation of Treatment Satisfaction and KarXT Utilization Registry (RESKU) · Bristol-Myers Squibb
HIV / STI (2 active studies)
Common conditions studied in Omaha
- Breast Cancer (16 active studies)
- Prostate Cancer (14 active studies)
- Multiple Myeloma (13 active studies)
- Non-Small Cell Lung Cancer (11 active studies)
- Ovarian Cancer (10 active studies)
- Heart Failure (9 active studies)
Leading research sponsors in Omaha
- University of Nebraska
- National Cancer Institute (NCI)
- AstraZeneca
- Children's Oncology Group
- SWOG Cancer Research Network
Frequently asked questions
How many paid clinical trials are currently recruiting in Omaha?
There are approximately 581 recruiting clinical trials in Omaha, Nebraska listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Omaha pay participants?
Most recruiting trials in Omaha compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Omaha?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Omaha?
The most common conditions under active study in Omaha include Breast Cancer (16), Prostate Cancer (14), Multiple Myeloma (13), Non-Small Cell Lung Cancer (11), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Omaha?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Omaha on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Omaha?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Omaha?
Recruiting research sites in Omaha include University of Nebraska Medical Center, Nebraska Cancer Specialists, Nebraska Medicine-Village Pointe, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Omaha right now?
The largest active categories in Omaha are Cancer & tumors (257), Cardiovascular (38), Diabetes & metabolic (17). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.