Paid Clinical Trials in Pierre, SD
As of July 2026, 20 paid clinical trials are recruiting in Pierre, South Dakota. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Pierre offers studies at sites including Avera Cancer Institute at Pierre for conditions such as Breast Cancer, Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Pierre
Trials by drug in Pierre
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20 clinical trials
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)
Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease
Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening
A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Participants With Advanced Breast Cancer
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial
APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation
A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer
Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
Avera Cancer Sequencing and Analytics Protocol (ASAP)
A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)
A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC
Top Research Study Locations in Pierre
Researchers run research studies in Pierre, SD at 7 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Avera Cancer Institute at Pierre | Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 9 |
| Avera Cancer Institute - Pierre | Metastatic Castration-resistant Prostate Cancer (mCRPC), Prostate Cancer Metastatic, Prostatic Neoplasms | 3 |
| Avera Cancer Institute - Pierre, SD | Breast Cancer | 1 |
| Avera Cancer Institute- Pierre | Colonic Diseases, Colorectal Neoplasms, Digestive System Diseases | 1 |
| Avera St. Mary's Hospital | Breast Cancer | 1 |
| Circle Clinical Research | Lung Cancer Diagnosis | 1 |
| Home-based telemedicine | Chronic Granulomatous Disease (CGD) | 1 |
Active & Upcoming Studies in Pierre (2026)
Recruiting trials in Pierre grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (18 active studies)
- A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus Ribociclib Plus Fulvestrant in Participants With Advanced Breast Cancer · Phase 2 · Hoffmann-La Roche
- A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02) · Phase 3 · AstraZeneca
Common conditions studied in Pierre
- Breast Cancer (4 active studies)
- Advanced Esophageal Adenocarcinoma (1 active study)
- Advanced Gastric Adenocarcinoma (1 active study)
- Advanced Gastroesophageal Junction Adenocarcinoma (1 active study)
- Anatomic Stage II Breast Cancer AJCC v8 (1 active study)
- Anatomic Stage IIIA Breast Cancer AJCC v8 (1 active study)
Leading research sponsors in Pierre
- National Cancer Institute (NCI)
- AstraZeneca
- NRG Oncology
- Alliance for Clinical Trials in Oncology
- Merck Sharp & Dohme LLC
Frequently asked questions
How many paid clinical trials are currently recruiting in Pierre?
There are approximately 20 recruiting clinical trials in Pierre, South Dakota listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Pierre pay participants?
Most recruiting trials in Pierre compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Pierre?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Pierre?
The most common conditions under active study in Pierre include Breast Cancer (4), Advanced Esophageal Adenocarcinoma (1), Advanced Gastric Adenocarcinoma (1), Advanced Gastroesophageal Junction Adenocarcinoma (1), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Pierre?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Pierre on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Pierre?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Pierre?
Recruiting research sites in Pierre include Avera Cancer Institute at Pierre, Avera Cancer Institute - Pierre, Avera Cancer Institute - Pierre, SD, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Pierre right now?
The largest active categories in Pierre are Cancer & tumors (18). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.