Solid tumor Clinical Trials in Portland, OR
As of September 2026, 41 paid clinical trials are recruiting for Solid tumor in Portland, Oregon. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Related specialties in Portland
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41 clinical trials for Solid tumor
·Clear filters·Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
FOG-001 in Locally Advanced or Metastatic Solid Tumors
A Study of ASP3082 in Adults With Advanced Solid Tumors
Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers
A Study of 177Lu-FAP-2286 in Advanced Solid Tumors
A Study of PHN-012 in Patients With Advanced Solid Tumors
A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers
DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors
A Clinical Study of YL205 in Patients With Advanced Solid Tumors
A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies
Study of AVZO-021 in Patients With Advanced Solid Tumors
A Study of PARG Inhibitor FORX-428 in Patients With Advanced Solid Tumors.
Study of RYZ401 in Subjects With Solid Tumors Expressing SSTRs.
Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmocodynamics and Preliminary Antitumor Activity of AT-1965 in Patients With Advanced, Refractory or Recurrent Solid Tumors
SW-682 in Advanced Solid Tumors
First-in-Human Study of DS-3939a in Participants With Advanced Solid Tumors
A Study of MGC026 in Participants With Advanced Solid Tumors
Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors
Phase I Study of Tolododekin Alfa (ANK-101) in Advanced Solid Tumors
FIH Study to Evaluate Safety, Tolerability, PK, PD & Preliminary Efficacy of AT03-65 With Advanced Solid Tumors
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer
Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer
Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study
Project: Every Child for Younger Patients With Cancer
Observational Study of Sex Differences in Symptoms During Immune Checkpoint Inhibitor Treatment for People With Cancer
Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors
CREATE: Art for Children With Cancer
A Clinical Trial to Evaluate the Safety, Tolerability and Clinical Efficacy of M3T01 Monotherapy and in Combination With Pembrolizumab and Other Systemic Therapies
Collection of Research Data and Samples From Patients Treated With Immunotherapy to Study Its Side Effects
Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced Esophagogastric, Hepatopancreaticobiliary, Colorectal or Lung Cancer
Axatilimab in Combination With Retifanlimab and Paclitaxel for the Treatment of Patients With Advanced or Metastatic Solid Tumors
Identifying and Caring for Individuals With Inherited Cancer Syndrome
A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study
Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors
Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors
Top Research Study Locations in Portland
Researchers run research studies in Portland, OR at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Oregon Health and Science University | Acute Myeloid Leukemia, ARDS, ARDS (Acute Respiratory Distress Syndrome) | 194 |
| Oregon Health & Science University | Heart Failure, Prostate Cancer, Alzheimer Disease | 169 |
| Providence Portland Medical Center | Acute Myeloid Leukemia, Breast Cancer, Malignant Solid Neoplasm | 109 |
| Providence Saint Vincent Medical Center | Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 86 |
| OHSU Knight Cancer Institute | Acute Myeloid Leukemia, Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm | 45 |
| Providence St. Vincent Medical Center | Carcinoma, Non-Small-Cell Lung, Cardiovascular Diseases, Coronary Artery Disease | 27 |
| VA Portland Health Care System, Portland, OR | Chronic Pain, Tinnitus, Alcohol Use Disorder | 26 |
| Oregon Health Sciences University | Cystic Fibrosis, Prostate Cancer, AAA | 19 |
| Oregon Health & Science University (OHSU) | Advanced Malignant Neoplasm, Advanced Solid Tumor, Aortic Insufficiency | 19 |
| Legacy Emanuel Children's Hospital | Acute Myeloid Leukemia, Ganglioneuroblastoma, Nodular, Malignant Solid Neoplasm | 18 |
| Kaiser Permanente Northwest | Lung Non-Small Cell Carcinoma, Breast Cancer, Recurrent Lung Non-Small Cell Carcinoma | 16 |
| Oregon Health and Sciences University | Acute Cannabis-induced CNS Depression, Acute Respiratory Failure, Anesthesia | 15 |
| Legacy Good Samaritan Hospital and Medical Center | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 14 |
| Providence Cancer Institute | Advanced Solid Tumor, Fallopian Tube Cancer, Non Small Cell Lung Cancer | 13 |
| OHSU | Acute Kidney Injury, Acute Monocytic Leukemia, Acute Myeloid Leukemia | 11 |
| Providence Cancer Institute Franz Clinic | Breast Cancer, Advanced Breast Cancer, Advanced or Metastatic Solid Tumors | 10 |
| Northwest Cancer Specialists, P.C. | Advanced Non-Small Cell Lung Cancer, Advanced Renal Cell Carcinoma, Advanced or Metastatic Renal Cell Carcinoma | 8 |
| Oregon Health & Sciences University | Cardiac Arrest, Complex Cardiovascular Surgery With Cardiopulmonary Bypass, Cystic Fibrosis | 7 |
| Portland VA Medical Center | Abdominal Aortic Aneurysm, Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum | 7 |
| The Oregon Clinic | Colitis, Ulcerative, Crohn Disease, Chronic Thromboembolic Pulmonary Hypertension | 7 |
| Kaiser Permanente Interstate Medical Office Central | Neoplasm Metastasis, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell | 6 |
| Oregon Health & Science University Hospital | Atrial Fibrillation, Basal Ganglia Intracerebral Hemorrhage, Coronary Artery Disease | 6 |
| EyeHealth Northwest | Age-Related Macular Degeneration, Age-related Macular Degeneration (AMD), Choroidal Neovascularization | 5 |
| Kaiser Permanente Center for Health Research | Clostridoides Difficile Associated Disease, Depression, Anxiety, School Health Services | 5 |
| Oregon Dermatology and Research Center | Actinic Keratosis, Moderate to Severe Glabellar Lines, Overweight or Obesity | 5 |
Active & Upcoming Studies in Portland (2026)
Recruiting trials in Portland grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (348 active studies)
- Maximizing Quality of Life After Cancer Through Rehabilitation · VA Office of Research and Development
- Symptom Trajectory Approaches to Research · University of Wisconsin, Madison
Neurology & pain (65 active studies)
- High-Intensity Focused Ultrasonic Ablation of the Centromedian Thalamic Nucleus for Treatment of Medically Refractory Generalized Epilepsy in Patients Ages 18 Years to 89 Years · Oregon Health and Science University
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
Cardiovascular (48 active studies)
- Precision T1D Platform - New Therapies for Cardio-Renal Complications · Phase 2 · Oregon Health and Science University
- A Prospective, Randomized Multicenter Clinical Trial of the TricValve® Transcatheter Bicaval Valve System in Subjects With Severe Tricuspid Regurgitation. · P+F Products + Features USA Inc.
Diabetes & metabolic (23 active studies)
- Precision T1D Platform - New Therapies for Cardio-Renal Complications · Phase 2 · Oregon Health and Science University
- A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus · Phase 3 · AstraZeneca
Mental health & behavior (18 active studies)
- Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression · Phase 3 · VA Office of Research and Development
- Digitally Enhanced Peer Doula Model for Perinatal Patients With Substance Use Disorder · Trustees of Dartmouth College
Eye & vision (15 active studies)
- A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated · Phase 1, Phase 2 · Boehringer Ingelheim
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
Pediatric (8 active studies)
- Implementing Powered Mobility in Early Childhood Settings for Children With Cerebral Palsy · Oregon Health and Science University
- A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT) · Phase 3 · Janssen Research & Development, LLC
Vaccines (5 active studies)
- A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age · Phase 3 · GlaxoSmithKline
- Immune-mediated Pathogenic Mechanisms of Neuro-PASC in Veterans · VA Office of Research and Development
Common conditions studied in Portland
- Acute Myeloid Leukemia (18 active studies)
- Endometrial Cancer (17 active studies)
- Breast Cancer (16 active studies)
- Heart Failure (14 active studies)
- Ovarian Cancer (13 active studies)
- Prostate Cancer (13 active studies)
Leading research sponsors in Portland
- Oregon Health and Science University
- OHSU Knight Cancer Institute
- National Cancer Institute (NCI)
- AstraZeneca
- VA Office of Research and Development
Frequently asked questions
How many paid clinical trials are currently recruiting in Portland?
There are approximately 1,003 recruiting clinical trials in Portland, Oregon listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Portland pay participants?
Most recruiting trials in Portland compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Portland?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Portland?
The most common conditions under active study in Portland include Acute Myeloid Leukemia (18), Endometrial Cancer (17), Breast Cancer (16), Heart Failure (14), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Portland?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Portland on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Portland?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Portland?
Recruiting research sites in Portland include Oregon Health and Science University, Oregon Health & Science University, Providence Portland Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Portland right now?
The largest active categories in Portland are Cancer & tumors (348), Neurology & pain (65), Cardiovascular (48). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.