Paid Clinical Trials in Portland, OR
As of June 2026, 1,089 paid clinical trials are recruiting in Portland, Oregon. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Portland offers studies at sites including Oregon Health and Science University for conditions such as Acute Myeloid Leukemia, Breast Cancer, Endometrial Cancer, Heart Failure. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Portland
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·Clear filters·↓ Download CSVAbout research studies in Portland
Portland has approximately 1,089 recruiting research studies across a wide range of therapeutic areas. Oregon hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.
Top Research Study Locations in Portland
Researchers run research studies in Portland, OR at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Oregon Health and Science University | Acute Myeloid Leukemia, Myelodysplastic Syndromes, ARDS | 212 |
| Oregon Health & Science University | Heart Failure, Alzheimer Disease, Dementia | 172 |
| Providence Portland Medical Center | Stage IV Lung Cancer AJCC v8, Acute Myeloid Leukemia, Malignant Solid Neoplasm | 124 |
| Providence Saint Vincent Medical Center | Stage IV Lung Cancer AJCC v8, Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8 | 93 |
| OHSU Knight Cancer Institute | Acute Myeloid Leukemia, Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm | 46 |
| Legacy Good Samaritan Hospital and Medical Center | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 | 24 |
| Providence St. Vincent Medical Center | Carcinoma, Non-Small-Cell Lung, Cardiovascular Diseases, Coronary Artery Disease | 24 |
| Oregon Health Sciences University | Breast Cancer, Cystic Fibrosis, Prostate Cancer | 22 |
| VA Portland Health Care System, Portland, OR | Chronic Pain, Atherosclerosis, Auditory Processing Disorder | 20 |
| Kaiser Permanente Northwest | Lung Non-Small Cell Carcinoma, Breast Cancer, Recurrent Lung Non-Small Cell Carcinoma | 19 |
| Legacy Emanuel Children's Hospital | Acute Myeloid Leukemia, Ganglioneuroblastoma, Nodular, Malignant Solid Neoplasm | 18 |
| Oregon Health & Science University (OHSU) | Advanced Malignant Neoplasm, Advanced Solid Tumor, Alzheimer Disease | 16 |
| Providence Cancer Institute | Advanced Solid Tumor, Fallopian Tube Cancer, Ovarian Cancer | 13 |
| OHSU | Acute Kidney Injury, Acute Monocytic Leukemia, Acute Myeloid Leukemia | 12 |
| Oregon Health and Sciences University | Acute Respiratory Failure, Anesthesia, Anesthesia Awareness | 12 |
| Providence Cancer Institute Franz Clinic | Advanced or Metastatic Solid Tumors, Breast Cancer, Glioma | 12 |
| Portland VA Medical Center | Abdominal Aortic Aneurysm, Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum | 10 |
| Oregon Dermatology and Research Center | Actinic Keratosis, Atopic Dermatitis, Dermatitis, Atopic | 8 |
| Oregon Health & Sciences University | ADHF, Cardiac Arrest, Cardio-Renal Syndrome | 8 |
| Kaiser Permanente Center for Health Research | Clostridioides Difficile Associated Disease, Depression, Anxiety, Diabetes Mellitus, Type 2 | 7 |
| Randall Children's Hospital | Neuroblastoma, Medulloblastoma, Pediatric Cancer | 7 |
| The Oregon Clinic | Idiopathic Pulmonary Fibrosis, Progressive Pulmonary Fibrosis, Chronic Thromboembolic Pulmonary Hypertension | 7 |
| Northwest Cancer Specialists, P.C. | Advanced Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC) | 6 |
| Kaiser Permanente Interstate Medical Office Central | Neoplasm Metastasis, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell | 6 |
| Oregon Health & Science University Hospital | Atrial Fibrillation, Coronary Artery Disease, Intracerebral Hemorrhage | 6 |
Active & Upcoming Studies in Portland (2026)
Recruiting trials in Portland grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (391 active studies)
- Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates · Phase 2 · University of Colorado, Denver
- Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study · Phase 4 · OHSU Knight Cancer Institute
Neurology & pain (68 active studies)
- Digital Treatment for Chronic Pain and Addiction in Veterans With Opioid Use Disorder Receiving Buprenorphine · Phase 3 · VA Office of Research and Development
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
Cardiovascular (48 active studies)
- Precision T1D Platform - New Therapies for Cardio-Renal Complications · Phase 2 · Oregon Health and Science University
- A Randomized Feasibility Trial Comparing Drospirenone and Norethindrone for Postpartum Hypertension Management in Preeclampsia · Phase 4 · Oregon Health and Science University
Diabetes & metabolic (23 active studies)
- Precision T1D Platform - New Therapies for Cardio-Renal Complications · Phase 2 · Oregon Health and Science University
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
Mental health & behavior (18 active studies)
- Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression · Phase 3 · VA Office of Research and Development
- Cervical Plexus Hydrodissection With D5W Versus NS for Treatment-Resistant PTSD · Phase 4 · Dr. Dean Reeves Clinic
Eye & vision (17 active studies)
- A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated · Phase 1, Phase 2 · Boehringer Ingelheim
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
Pediatric (14 active studies)
- Implementing Powered Mobility in Early Childhood Settings for Children With Cerebral Palsy · Oregon Health and Science University
- A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT) · Phase 3 · Janssen Research & Development, LLC
Vaccines (6 active studies)
- Immune-mediated Pathogenic Mechanisms of Neuro-PASC in Veterans · VA Office of Research and Development
- Clinical Outcomes and Pharmacotherapy Effectiveness in the VA Health Care System (COPE-VA) · VA Office of Research and Development
HIV / STI (1 active study)
- DBS TaT in Peer-assisted Telemedicine for Hepatitis C · Oregon Health and Science University
Common conditions studied in Portland
- Acute Myeloid Leukemia (20 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Breast Cancer (20 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Endometrial Cancer (19 active studies). Recruiting Endometrial Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Heart Failure (17 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Ovarian Cancer (15 active studies). Ovarian cancer research examines PARP inhibitors, maintenance therapies, and antibody-drug conjugates for recurrent and platinum-resistant disease.
- Advanced Solid Tumor (14 active studies). Recruiting Advanced Solid Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Portland
- Oregon Health and Science University
- National Cancer Institute (NCI)
- OHSU Knight Cancer Institute
- AstraZeneca
- SWOG Cancer Research Network
Local regulations and guidelines
Clinical trials in Oregon are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Oregon research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Portland. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Portland
Hipa.ai aggregates every recruiting study in Portland from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Portland?
There are approximately 1,089 recruiting clinical trials in Portland, Oregon listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Portland pay participants?
Most recruiting trials in Portland compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Portland?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Portland?
The most common conditions under active study in Portland include Acute Myeloid Leukemia (20), Breast Cancer (20), Endometrial Cancer (19), Heart Failure (17), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Portland?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Portland on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Portland?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Portland?
Recruiting research sites in Portland include Oregon Health and Science University, Oregon Health & Science University, Providence Portland Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Portland right now?
The largest active categories in Portland are Cancer & tumors (391), Neurology & pain (68), Cardiovascular (48). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.