Family Communications After Genetic Testing
for Colon Adenocarcinoma
Sites in Rapid City +289 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07143487·Recruiting·Listed Aug 2025
Clinical Trials at Rapid City Regional Hospital
As of August 2026, 16 paid clinical trials are recruiting at Rapid City Regional Hospital, located at 353 FAIRMONT BLVD, RAPID CITY, SD 57701-7375, phone (605) 719-1000 in Rapid City, South Dakota. Active studies at this site cover conditions such as Heart Failure, Obesity and Advanced Esophageal Adenocarcinoma. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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16 clinical trials at Rapid City Regional Hospital
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Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
for Stage III Colon Cancer
Sites in Rapid City, Aberdeen +913 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
for Advanced Esophageal Adenocarcinoma
Drug: Nivolumab
Sites in Rapid City, Aberdeen +630 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05677490·Phase 3·Recruiting·Listed Jan 2023
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial
for Plasma Cell Myeloma
Sites in Rapid City +304 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT04566328·Phase 3·Recruiting·Listed Sep 2020
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
for Anatomic Stage I Breast Cancer AJCC v8
Sites in Rapid City, Sioux Falls +591 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT06876714·Phase 3·Recruiting·Listed Mar 2025
Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma
for Smoldering Plasma Cell Myeloma
Drug: Daratumumab
Sites in Rapid City +483 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT03937635·Phase 3·Recruiting·Listed May 2019
E-Mindfulness Approaches for Living After Breast Cancer
for Breast Cancer
Sites in Rapid City, Sioux Falls +372 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18 - 50
Code: NCT06748222·Phase 3·Recruiting·Listed Dec 2024
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
for Advanced Malignant Solid Neoplasm
Sites in Rapid City, Sioux Falls +429 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: All ages
Code: NCT05564377·Phase 2·Recruiting·Listed Oct 2022
Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial
for Advanced Esophageal Adenocarcinoma
Drug: Nivolumab
Sites in Rapid City, Sioux Falls +336 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06203600·Phase 2, Phase 3·Recruiting·Listed Jan 2024
BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study
for Clinical Stage III Cutaneous Melanoma AJCC v8
Drug: Cabozantinib
Sites in Rapid City, Sioux Falls +206 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT05136196·Phase 2·Recruiting·Listed Nov 2021
Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial
for Advanced Lung Non-Small Cell Carcinoma
Sites in Rapid City, Sioux Falls +268 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 70+
Code: NCT06096844·Phase 3·Recruiting·Listed Oct 2023
Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial
for Castration-Sensitive Prostate Carcinoma
Drug: Apalutamide
Sites in Rapid City, Sioux Falls +193 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: Male·Age: 18+
Code: NCT06931340·Phase 3·Recruiting·Listed Apr 2025
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
for Previously Treated Non-Small Cell Lung Cancer
Sites in Rapid City, Sioux Falls +948 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT03851445·Phase 2, Phase 3·Recruiting·Listed Feb 2019
Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations
for Locally Advanced Pancreatic Adenocarcinoma
Sites in Rapid City +271 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT06998940·Phase 3·Recruiting·Listed May 2025
Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)
for Recurrent Lung Non-Small Cell Carcinoma
Drug: Cemiplimab
Sites in Rapid City, Sioux Falls +379 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT06616584·Phase 2, Phase 3·Recruiting·Listed Sep 2024
Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer
for Locally Advanced Hepatocellular Carcinoma
Drug: Atezolizumab
Sites in Rapid City +11 more locations
Sponsor: Academic and Community Cancer Research United
Sex: All·Age: 18+
Code: NCT05168163·Phase 2·Recruiting·Listed Dec 2021
Common conditions studied in Rapid City
- Heart Failure (5 active studies)
- Obesity (4 active studies)
- Advanced Esophageal Adenocarcinoma (2 active studies)
- Advanced Gastric Adenocarcinoma (2 active studies)
- Advanced Gastroesophageal Junction Adenocarcinoma (2 active studies)
- Cardiovascular Disease (2 active studies)
Leading research sponsors in Rapid City
- AstraZeneca
- Alliance for Clinical Trials in Oncology
- Amgen
- National Cancer Institute (NCI)
- Novo Nordisk A/S
Frequently asked questions
How many paid clinical trials are currently recruiting in Rapid City?
There are approximately 63 recruiting clinical trials in Rapid City, South Dakota listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Rapid City pay participants?
Most recruiting trials in Rapid City compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Rapid City?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Rapid City?
The most common conditions under active study in Rapid City include Heart Failure (5), Obesity (4), Advanced Esophageal Adenocarcinoma (2), Advanced Gastric Adenocarcinoma (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Rapid City?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Rapid City on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Rapid City?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Rapid City?
Recruiting research sites in Rapid City include Rapid City Regional Hospital, Monument Health Clinical Research, Health Concepts, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Rapid City right now?
The largest active categories in Rapid City are Cancer & tumors (19), Cardiovascular (10), Diabetes & metabolic (7). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of Rapid City Regional Hospital?
Rapid City Regional Hospital is located at 353 FAIRMONT BLVD, RAPID CITY, SD 57701-7375. Use the Google Maps link in the intro above to get directions.
How do I contact Rapid City Regional Hospital?
You can reach Rapid City Regional Hospital by phone at (605) 719-1000. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.