Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
for Stage III Colon Cancer
Sites in Richardson, Dallas +913 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021
Clinical Trials at UT Southwestern Clinical Center at Richardson/Plano
As of August 2026, 28 paid clinical trials are recruiting at UT Southwestern Clinical Center at Richardson/Plano in Richardson, Texas. Active studies at this site cover conditions such as Schizophrenia, Major Depressive Disorder (MDD) and Stage IVB Prostate Cancer AJCC v8. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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28 clinical trials at UT Southwestern Clinical Center at Richardson/Plano
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Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
for Anatomic Stage II Breast Cancer AJCC v8
Sites in Richardson, Dallas +777 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05812807·Phase 3·Recruiting·Listed Apr 2023
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
for Advanced Esophageal Adenocarcinoma
Drug: Nivolumab
Sites in Richardson, Dallas +630 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05677490·Phase 3·Recruiting·Listed Jan 2023
Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma
for Smoldering Plasma Cell Myeloma
Drug: Daratumumab
Sites in Richardson, Dallas +482 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT03937635·Phase 3·Recruiting·Listed May 2019
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
for Bladder Adenocarcinoma
Drug: Cabozantinib
Sites in Richardson, Dallas +221 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT03866382·Phase 2·Recruiting·Listed Mar 2019
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
for Fallopian Tube Endometrioid Adenocarcinoma
Drug: Bevacizumab
Sites in Richardson, Dallas +653 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT06580314·Phase 3·Recruiting·Listed Aug 2024
Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer
for Locally Advanced Cervical Adenocarcinoma
Sites in Richardson, Dallas +305 more locations
Sponsor: National Cancer Institute (NCI)
Sex: Female·Age: 18+
Code: NCT07061977·Phase 3·Recruiting·Listed Jul 2025
Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study
for Muscle Invasive Bladder Urothelial Carcinoma
Sites in Richardson, Dallas +442 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT05987241·Phase 2, Phase 3·Recruiting·Listed Aug 2023
Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging
for Biochemically Recurrent Prostate Carcinoma
Drug: Apalutamide
Sites in Richardson, Dallas +276 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: Male·Age: 18+
Code: NCT04423211·Phase 3·Recruiting·Listed Jun 2020
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
for Clear Cell Renal Cell Carcinoma
Sites in Richardson, Dallas +406 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT06661720·Phase 3·Recruiting·Listed Oct 2024
Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial
for Metastatic Renal Cell Carcinoma
Sites in Richardson, Dallas +278 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT05327686·Phase 2·Recruiting·Listed Apr 2022
Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial
for Advanced Lung Non-Small Cell Carcinoma
Sites in Richardson, Dallas +268 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 70+
Code: NCT06096844·Phase 3·Recruiting·Listed Oct 2023
Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer
for Renal Pelvis and Ureter Urothelial Carcinoma
Drug: Durvalumab
Sites in Richardson, Dallas +151 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04628767·Phase 2, Phase 3·Recruiting·Listed Nov 2020
Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial
for Muscle Invasive Bladder Urothelial Carcinoma
Sites in Richardson, Dallas +151 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT07061964·Phase 2·Recruiting·Listed Jul 2025
A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer
for Locally Advanced Urothelial Carcinoma
Sites in Richardson, Dallas +157 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06524544·Phase 3·Recruiting·Listed Jul 2024
Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial
for Castration-Sensitive Prostate Carcinoma
Drug: Apalutamide
Sites in Richardson, Dallas +193 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: Male·Age: 18+
Code: NCT06931340·Phase 3·Recruiting·Listed Apr 2025
Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer
for Locally Advanced Adrenal Cortical Carcinoma
Drug: Cabozantinib
Sites in Richardson, Dallas +77 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 12+
Code: NCT06900595·Phase 2·Recruiting·Listed Mar 2025
Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma
for Endometrial Adenocarcinoma
Drug: Ipilimumab
Sites in Richardson, Dallas +123 more locations
Sponsor: National Cancer Institute (NCI)
Sex: Female·Age: 18+
Code: NCT05112601·Phase 2·Recruiting·Listed Nov 2021
Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial
for Castration-Resistant Prostate Carcinoma
Sites in Richardson, Dallas +98 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT06632977·Phase 2·Recruiting·Listed Oct 2024
Testing the Addition of Immunotherapy Before Surgery for Patients With Sarcomatoid Mesothelioma
for Pleural Biphasic Mesothelioma
Sites in Richardson, Dallas +102 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05647265·Phase 2·Recruiting·Listed Dec 2022
Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity
for Gastric Adenocarcinoma
Sites in Richardson, Dallas +76 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT07001748·Phase 2, Phase 3·Recruiting·Listed Jun 2025
Impact of Sentinel Lymph Node Mapping on Patient Reported Lower Extremity Limb Dysfunction in Stage I Endometrial Cancer
for Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
Sites in Richardson, Dallas +39 more locations
Sponsor: NRG Oncology
Sex: Female·Age: 18+
Code: NCT05646316·Phase 3·Recruiting·Listed Dec 2022
Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial
for Metastatic Colorectal Carcinoma
Sites in Richardson, Dallas +52 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT05863195·Phase 3·Recruiting·Listed May 2023
Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
for Autoimmune Disease
Drug: Nivolumab
Sites in Richardson, Dallas +39 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT03816345·Phase 1·Recruiting·Listed Jan 2019
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity
for Cardiotoxicity
Sites in Richardson, Dallas +142 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT03418961·Phase 3·Recruiting·Listed Feb 2018
Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial
for Metastatic Clear Cell Renal Cell Carcinoma
Sites in Richardson, Dallas +338 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT04510597·Phase 3·Recruiting·Listed Aug 2020
Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer
for Castration Levels of Testosterone
Sites in Richardson, Dallas +292 more locations
Sponsor: SWOG Cancer Research Network
Sex: Male·Age: 18+
Code: NCT03678025·Phase 3·Recruiting·Listed Sep 2018
Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma
for Endometrial Carcinoma
Sites in Richardson, Dallas +329 more locations
Sponsor: National Cancer Institute (NCI)
Sex: Female·Age: 18+
Code: NCT05256225·Phase 3·Recruiting·Listed Feb 2022
Common conditions studied in Richardson
- Schizophrenia (8 active studies)
- Major Depressive Disorder (MDD) (5 active studies)
- Stage IVB Prostate Cancer AJCC v8 (5 active studies)
- Stage IV Renal Cell Cancer AJCC v8 (3 active studies)
- Autism (2 active studies)
- Bipolar Disorder (2 active studies)
Leading research sponsors in Richardson
- The University of Texas at Dallas
- National Cancer Institute (NCI)
- Alliance for Clinical Trials in Oncology
- Bristol-Myers Squibb
- ECOG-ACRIN Cancer Research Group
Frequently asked questions
How many paid clinical trials are currently recruiting in Richardson?
There are approximately 77 recruiting clinical trials in Richardson, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Richardson pay participants?
Most recruiting trials in Richardson compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Richardson?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Richardson?
The most common conditions under active study in Richardson include Schizophrenia (8), Major Depressive Disorder (MDD) (5), Stage IVB Prostate Cancer AJCC v8 (5), Stage IV Renal Cell Cancer AJCC v8 (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Richardson?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Richardson on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Richardson?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Richardson?
Recruiting research sites in Richardson include UT Southwestern Clinical Center at Richardson/Plano, Pillar Clinical Research - Richardson, University of Texas at Dallas, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Richardson right now?
The largest active categories in Richardson are Cancer & tumors (31), Mental health & behavior (17), Neurology & pain (4). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
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