Oncology Clinical Trials in Rochester, NY
As of August 2026, 100 paid clinical trials are recruiting for Oncology in Rochester, New York. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Filter results
100 clinical trials for Oncology
·Clear filters·A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)
A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer
A Study of ASP3082 in Adults With Advanced Solid Tumors
Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia
A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%
Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC
SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
A Study of LY4584180 in Adult Participants With Previously Treated Blood Cancers
Adjuvant Temozolomide ± 5-Aminolevulinic Acid + Low Intensity Diffuse Ultrasound Sonodynamic Therapy System for Newly Diagnosed Glioblastoma
A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007)
A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma
Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma
A Clinical Trial to Evaluate the Safety and Efficacy of COM701 in Relapsed Platinum Sensitive Ovarian Cancer
Study to Assess Safety and Tolerability of OPN-6602 in Subjects With Relapsed and/or Refractory Multiple Myeloma
Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer
Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier
A Study to Evaluate Preventive Treatments for GPRC5D-related Oral Events
A Study of CTX-712 in Relapsed/Refractory Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndromes
A Novel Vaccine (EO2463) as Monotherapy and in Combination, for Treatment of Patients With Indolent Non-Hodgkin Lymphoma
Stratagen Quantitative Prostate MRI Platform Pilot Study
Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL
A Pilot Randomized Controlled Trial of a Social Network Intervention
Exercise and Cognitive Rehabilitation Interventions for Older Cancer Survivors
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer
MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)
Top Research Study Locations in Rochester
Researchers run research studies in Rochester, NY at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Rochester | Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Malignant Solid Neoplasm | 161 |
| University of Rochester Medical Center | Healthy, Pulmonary Hypertension, Breathing | 114 |
| Rochester Clinical Research, LLC | Obesity, Overweight, Chronic Pain | 13 |
| Rochester General Hospital | Aortic Valve Stenosis, Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm | 12 |
| Highland Hospital | Stage IVA Prostate Cancer AJCC v8, Abscess, Advanced Colorectal Carcinoma | 11 |
| Rochester Clinical Research | Obesity, Overweight, Acute Migraine | 8 |
| Pluta Cancer Center | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 7 |
| Wilmot Cancer Institute | Breast Cancer, Acute Leukemia, Aplastic Anemia | 7 |
| University of Rochester Medical Center (URMC) | Adult Acute Myeloid Leukemia, Hpv, Phenylketonuria | 5 |
| GSK Investigational Site | Gastrointestinal Neoplasms, Irritable Bowel Syndrome, Tumours, Gynecological | 4 |
| Strong Memorial Hospital | Aortic Stenosis, Atrial Fibrillation, Cardiotoxicity | 4 |
| Unity Park Ridge Campus | Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Early Stage HER2+ Breast Cancer | 4 |
| University of Rochester Medical Center Strong Memorial | Cystic Fibrosis, Cystic Fibrosis (CF) | 3 |
| University of Rochester Wilmot Cancer Institute | Angiosarcoma, Breast Cancer, Breast Neoplasms | 3 |
| Wilmot Cancer Institute Radiation Oncology at Greece | Advanced Colorectal Carcinoma, Advanced Lung Non-Small Cell Carcinoma, Advanced Pancreatic Adenocarcinoma | 3 |
| AD-CARE, University of Rochester Medical Center | Alzheimers Disease | 2 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, MASH With Fibrosis, NASH - Nonalcoholic Steatohepatitis | 2 |
| American Thrombosis and Hemostasis Network | Bleeding Disorder, Connective Tissue Disorder, Factor IX Deficiency | 2 |
| Chester F. Carlson Center for Imaging Science | Distance Viewing, L- and M-cone Modulation Only, L- and S-cone Modulation Only | 2 |
| Gastroenterology Group Of Rochester, LLP | Moderately to Severely Active Crohns Disease, Moderately to Severely Active Ulcerative Colitis | 2 |
| Gastroenterology Group of Rochester | Colonic Polyps, Crohn Disease (CD), Ulcerative Colitis (UC) | 2 |
| Mayo Clinic | Lymphedema, Breast Cancer, Solid and Hematological Malignancies | 2 |
| Mt. Hope Family Center | Fetal Alcohol Spectrum Disorders, Posttraumatic Stress Disorder | 2 |
| Retina Associates of Western NY, P.C. | Epiretinal Membrane, Proliferative Diabetic Retinopathy (PDR) | 2 |
| Retina Associates of Western New York | Age Related Macular Degeneration (AMD), DME, Diabetic Macular Edema | 2 |
Active & Upcoming Studies in Rochester (2026)
Recruiting trials in Rochester grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (177 active studies)
- Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatment Regimen (Cytarabine and Daunorubicin, "7+3") for Core Binding Factor Acute Myeloid Leukemia (CBF-AML) to Improve Response (A MYELOMATCH Treatment Trial) · Phase 2 · National Cancer Institute (NCI)
- Tumor-Lymph Node Mapping · University of Rochester
Neurology & pain (32 active studies)
- A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Chronic Low Back Pain · Phase 2 · Eli Lilly and Company
- A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine · Phase 3 · Kallyope Inc.
Cardiovascular (24 active studies)
- The Benefits of Home Exercise in Pulmonary Hypertension Interstitial Lung Disease · University of Rochester
- A Comparative, Randomized, Investigator-blind, Active-controlled, Parallel-group, Multicenter, Clinical Endpoint Study · Phase 3 · YS Life Science Co., Ltd.
Diabetes & metabolic (18 active studies)
Mental health & behavior (11 active studies)
- Deaf CBT-TS to Reduce Suicide Risk · University of Rochester
- Ketamine-Assisted Psychotherapy for Treatment-Resistant Depression · Phase 2 · University of Rochester
Eye & vision (9 active studies)
- BriTer Eyez Moisture Vue™ On-Demand Disposable Moisture Chamber · University of Rochester
- A Comparative, Randomized, Investigator-blind, Active-controlled, Parallel-group, Multicenter, Clinical Endpoint Study · Phase 3 · YS Life Science Co., Ltd.
Pediatric (7 active studies)
- Tumor-Lymph Node Mapping · University of Rochester
- Caffeine Optimization for Oxygen Saturation Index in ELBW Infants · Phase 2 · University of Rochester
HIV / STI (4 active studies)
- A Trial to Evaluate the Safety and Tolerability of DV700P-RNA and DV701B1.1-RNA Immunization in Combination With Antiretroviral Analytical Treatment Interruption (ATI) in People Living With HIV for Elicitation of V3-glycan Antibodies · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- Phase 1 Study of CH505 HIV Vaccine Nanoparticles and mRNA Boosters in Healthy Adults · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
Vaccines (2 active studies)
- A Study to Learn About Revaccination With a Vaccine Called RSVpreF in Immunocompromised Adults · Phase 3 · Pfizer
- SAVE: School Ambassadors for Vaccine Education · University of Rochester
Common conditions studied in Rochester
- Acute Myeloid Leukemia (12 active studies)
- Breast Cancer (10 active studies)
- Obesity (9 active studies)
- Overweight (7 active studies)
- Cancer (6 active studies)
- Prostate Cancer (6 active studies)
Leading research sponsors in Rochester
- University of Rochester
- National Cancer Institute (NCI)
- Eli Lilly and Company
- SWOG Cancer Research Network
- Children's Oncology Group
Frequently asked questions
How many paid clinical trials are currently recruiting in Rochester?
There are approximately 475 recruiting clinical trials in Rochester, New York listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Rochester pay participants?
Most recruiting trials in Rochester compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Rochester?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Rochester?
The most common conditions under active study in Rochester include Acute Myeloid Leukemia (12), Breast Cancer (10), Obesity (9), Overweight (7), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Rochester?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Rochester on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Rochester?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Rochester?
Recruiting research sites in Rochester include University of Rochester, University of Rochester Medical Center, Rochester Clinical Research, LLC, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Rochester right now?
The largest active categories in Rochester are Cancer & tumors (177), Neurology & pain (32), Cardiovascular (24). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.