Paid Clinical Trials in Tyler, TX
As of June 2026, 163 paid clinical trials are recruiting in Tyler, Texas. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Tyler offers studies at sites including Tyler Research Institute, LLC for conditions such as Crohn's Disease, Ulcerative Colitis, Multiple Myeloma, Endometrial Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Tyler
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·Clear filters·↓ Download CSVAbout research studies in Tyler
Tyler has approximately 163 recruiting research studies across a wide range of therapeutic areas. Texas hosts major cancer and cardiovascular research centers including MD Anderson Cancer Center, Baylor College of Medicine, UT Southwestern Medical Center, and the Texas Medical Center — the largest medical complex in the world.
Top Research Study Locations in Tyler
Researchers run research studies in Tyler, TX at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Tyler Research Institute, LLC | Crohn's Disease, Ulcerative Colitis, Colitis, Ulcerative | 12 |
| Texas Oncology - Northeast Texas | Advanced Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC) | 9 |
| CHRISTUS Trinity Mother Frances Health System | Atrial Fibrillation, Beta-blocker Therapy, Cardiomyopathy | 5 |
| Texas Oncology | Advanced/Metastatic Solid Tumors, Colorectal Cancer, Esophageal Cancer | 5 |
| Texas Oncology - Tyler | Breast Cancer, Bone Metastases From Solid Tumors, Cancer | 5 |
| Tyler Research Institute | Ulcerative Colitis, Obesity or Overweight, Crohn's Disease | 5 |
| Precision Spine Care | Degenerative Disc Disease, Degenerative Disc Disease (DDD), Disc Degeneration | 4 |
| Texas Oncology - Northeast | Advanced Lung Cancer, Carcinoma, Non-Small-Cell Lung, Leukemia, Myeloid, Acute | 4 |
| HOPE Cancer Center of East Texas | Follicular Lymphoma (FL), Pancreatic Cancer Metastatic, Pancreatic Cancer Stage IV | 3 |
| Texas Oncology, P.A. - Tyler | Gastric Cancer, Gastroesophageal Junction Cancer, Metastatic Castration-resistant Prostate Cancer | 3 |
| Texas Oncology-Northeast Texas | Breast Cancer, Breast Neoplasms, Non-Small Cell Lung Cancer Metastatic | 3 |
| Tyler Retina Consultants | DME, Diabetic Macular Edema, Diabetic Macular Edema (DME) | 3 |
| University of Texas Health Center at Tyler | KRAS G12C Lung Cancer, Moderately to Severely Active Crohns Disease, Moderately to Severely Active Ulcerative Colitis | 3 |
| GSK Investigational Site | Multiple Myeloma, Neoplasms, Newly Diagnosed Multiple Myeloma | 2 |
| Texas Oncology - Northeast Texas ( Site 8002) | Cervical Cancer, Endometrial Cancer | 2 |
| Texas Oncology Northeast Texas | Extensive Stage Small-cell Lung Cancer, Metastatic Castration-resistant Prostate Cancer, Small-cell Lung Cancer | 2 |
| Texas Oncology Tyler | Chronic Lymphocytic Leukemia, CLL, Small Lymphocytic Lymphoma | 2 |
| Texas Oncology, P.A. - Oncology | Advanced Solid Tumor, Limited-stage Small Cell Lung Cancer (LS-SCLC), Malignant Peripheral Nerve Sheath Tumors | 2 |
| Texas Oncology- Northeast Texas | B-Cell Non-Hodgkins Lymphoma, Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC) | 2 |
| Texas Oncology-Tyler | Non-Small Cell Lung Cancer, Ovarian Cancer | 2 |
| The University of Texas Health Science Center at Tyler | Carcinoma, Non-Small-Cell Lung, Extensive Stage Small Cell Lung Cancer (ES-SCLC) | 2 |
| Tyler Cardiovascular Consultants | Atrial Fibrillation (AF), Cardiovascular Disease | 2 |
| Tyler Research Institute, LLC - Site Number: 8400095 | Ulcerative Colitis | 2 |
| UT Health East Texas HOPE Cancer Center | Carcinoma, Non-Small Cell Lung, Colorectal Neoplasms, Cutaneous Squamous Cell Cancer | 2 |
| University of Texas Health Science Center at Tyler | Bronchiectasis, Extensive Stage Small-cell Lung Cancer, Small-cell Lung Cancer | 2 |
Active & Upcoming Studies in Tyler (2026)
Recruiting trials in Tyler grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (82 active studies)
- A Phase III Trial of BNT324 Versus Docetaxel in Metastatic Castration-resistant Prostate Cancer · Phase 3 · BioNTech SE
- A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201) · Phase 3 · Bristol-Myers Squibb
Cardiovascular (15 active studies)
- A Global Study Comparing Pulsed Field Ablation With Electrographic Flow Mapping Versus Posterior Wall Ablation for Persistent Atrial Fibrillation · Boston Scientific Corporation
- CCM OPEN HF Registry · Impulse Dynamics
Eye & vision (7 active studies)
- Study Evaluating the Efficacy and Safety of Chloroprocaine HCl Ophthalmic Gel 3% vs Proparacaine Ophthalmic Solution 0.5% Plus Subconjunctival Lidocaine in Patients Undergoing Intravitreal Injections · Phase 4 · Harrow Inc
- Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS) · Phase 3 · Adverum Biotechnologies, Inc.
Neurology & pain (5 active studies)
- Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain · Phase 3 · Saol Therapeutics Inc
- Clinical Trial Evaluating the Safety and Efficacy of Nucleus Pulposus Allograft in Participants With Degenerative Disc Disease · VIVEX Biologics, Inc.
Diabetes & metabolic (3 active studies)
- Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study · Phase 3 · Eli Lilly and Company
- Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight · Phase 3 · Eli Lilly and Company
Common conditions studied in Tyler
- Crohn's Disease (11 active studies). Recruiting Crohn's Disease studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Ulcerative Colitis (8 active studies). Ulcerative colitis trials examine biologic therapies, S1P receptor modulators, and oral small molecules for steroid-sparing remission.
- Multiple Myeloma (6 active studies). Recruiting Multiple Myeloma studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Endometrial Cancer (5 active studies). Recruiting Endometrial Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Non-Small Cell Lung Cancer (5 active studies). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.
- Breast Cancer (4 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
Leading research sponsors in Tyler
- AstraZeneca
- Merck Sharp & Dohme LLC
- AbbVie
- Eli Lilly and Company
- Janssen Research & Development, LLC
Local regulations and guidelines
Clinical trials in Texas are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Trials run in Texas must also comply with the Texas Medical Privacy Act (TMPA), which extends federal HIPAA protections to a broader range of entities handling participant data.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Tyler. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Tyler
Hipa.ai aggregates every recruiting study in Tyler from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Tyler?
There are approximately 163 recruiting clinical trials in Tyler, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Tyler pay participants?
Most recruiting trials in Tyler compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Tyler?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Tyler?
The most common conditions under active study in Tyler include Crohn's Disease (11), Ulcerative Colitis (8), Multiple Myeloma (6), Endometrial Cancer (5), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Tyler?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Tyler on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Tyler?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Tyler?
Recruiting research sites in Tyler include Tyler Research Institute, LLC, Texas Oncology - Northeast Texas, CHRISTUS Trinity Mother Frances Health System, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Tyler right now?
The largest active categories in Tyler are Cancer & tumors (82), Cardiovascular (15), Eye & vision (7). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.