Bevacizumab, Docetaxel, and Gemcitabine Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer

Part of paid clinical trials in Cleveland, Ohio.

Sponsor
Nathan Pennell, MD, PhD
Study ID
NCT00970684
Phase
PHASE2
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 120 Years
Healthy Volunteers
Not accepted

Interventions

  • bevacizumab — BIOLOGICAL
    15 mg/kg on day 1 of a 21-day cycle
  • docetaxel — DRUG
    75 mg/m2 on day 1
  • gemcitabine hydrochloride — DRUG
    900 mg/m2 on days 1, and 8,

Study Details

RATIONALE: Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Drugs used in chemotherapy, such as docetaxel and gemcitabine hydrochloride, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving bevacizumab together with docetaxel and gemcitabine hydrochloride may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving bevacizumab together with docetaxel and gemcitabine hydrochloride works in treating patients with stage IIIB, stage IV, or recurrent non-small cell lung cancer.

Key Dates

First listed
Sep 2, 2009
Start date
Sep 30, 2009
Status verified
Jul 2022
Primary completion
Sep 30, 2011
Completion
Sep 30, 2011

Study Design

Enrollment
13 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Bevacizumab, Docetaxel, and Gemcitabine
    Treatment repeats every 21 days for up to 6 courses.

Primary Outcome Measure

Progression Free Survival(PFS) [ Time Frame: 1 year ]

Locations (4)

FacilityCityStateZIPSite coordinators
Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer CenterClevelandOhio44106-
Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer CenterClevelandOhio44195-
Fairview Hospital, Moll PavilionClevelandOhio44111-
Hillcrest Hospital, a Cleveland Clinic HospitalMayfield HeightsOhio44124-

Find similar trials in Cleveland, OH

By condition
Lung cancer
By specialty
OncologyLung oncologyLung disease
By research site
Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center· Cleveland, OHCleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center· Cleveland, OHFairview Hospital, Moll Pavilion· Cleveland, OHHillcrest Hospital, a Cleveland Clinic Hospital· Mayfield Heights, OH

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