Lung oncology Clinical Trials in Cleveland, OH
As of September 2026, 38 paid clinical trials are recruiting for Lung oncology in Cleveland, Ohio. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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38 clinical trials for Lung oncology
·Clear filters·Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer
Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)
Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer
Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer
A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)
A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors
A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
First in Human Study of TUB-030 in Patients With Advanced Solid Tumors
A Phase 1 Study of LNCB74 in Advanced Solid Tumors
A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers
Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
A Clinical Trial to Test if an Investigational Combination Therapy With BNT326 and BNT327 is Safe and Potentially Beneficial for People With Advanced Non-small Cell Lung Cancer (NSCLC)
Phase 2 Study for the Patient, Who Has Diagnosed With Small Cell Lung Cancer (SCLC) or Non Small Cell Lung Cancer (NSCLC) or Renal Cell Carcinoma (RCC) and Finished the First Line Stand Treatment , Need More Treatment
Real World Treatment Experience of Patients With Breast, Lung, Ovarian, Multiple Myeloma, or Acute Myelogenous Leukemia Using Remote Symptom Monitoring
A Study to Assess the Efficacy of WSD0922-FU in Patients With C797S+ Advanced Non-small Cell Lung Cancer
A Phase 1 Dose Escalation Study of ZG006 in Patients With Small Cell Lung Cancer
First in Human Study of TORL-1-23 in Participants With Advanced Cancer
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
The Vanguard Study: Testing a New Way to Screen for Cancer
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
Pulmonary Rehabilitation in Advanced Lung Cancer Survivors
Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation
Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer
A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors
Top Research Study Locations in Cleveland
Researchers run research studies in Cleveland, OH at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Cleveland Clinic | Heart Failure, Cardiovascular Diseases, Colorectal Cancer | 362 |
| University Hospitals Cleveland Medical Center | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 156 |
| Cleveland Clinic Foundation | Heart Failure, COPD, Stroke | 143 |
| Case Western Reserve University | Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Dementia | 76 |
| MetroHealth Medical Center | Spinal Cord Injuries, Spinal Cord Injury Cervical, Stage IVB Prostate Cancer AJCC v8 | 35 |
| The Cleveland Clinic Foundation | Heart Diseases, Aortic Valve Insufficiency, Cardiovascular Diseases | 28 |
| Rainbow Babies and Childrens Hospital | Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia, Down Syndrome | 26 |
| Louis Stokes VA Medical Center, Cleveland, OH | Spinal Cord Injury, Diabetes, Parkinson's Disease | 24 |
| Cleveland Clinic Main Campus | Breast Cancer, Abdominal Wall Hernia, Blood Pressure | 18 |
| The Cleveland Clinic | Depression / Major Depressive Disorder, Hopelessness, Suicidal Ideation | 17 |
| Cleveland Clinic Cancer Center/Fairview Hospital | Ovarian Carcinoma, Anatomic Stage IV Breast Cancer AJCC v8, Breast Cancer | 13 |
| University Hospitals | B Cell Lymphoma, Bladder Pain Syndrome, CLL | 12 |
| UH Cleveland Medical Center | Breast Cancer, Acute Decompensated Heart Failure, Atrial Fibrillation | 11 |
| University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center | Acute Lymphocytic Leukemia, Bile Duct Cancer, Brain Metastases | 11 |
| University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center | Pancreatic Cancer, Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum | 10 |
| Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center | Acute Myeloid Leukemia, Cyst of Pancreas, Cytokine Release Syndrome | 10 |
| Case Comprehensive Cancer Center, Cleveland Clinic Foundation Taussig Cancer Institute | Amyloid Light-chain Amyloidosis, B-cell Non Hodgkin Lymphoma, Basal Cell Carcinoma | 8 |
| Cleveland Clinic Taussig Cancer Center | Glioma, Advanced Solid Tumor, Barrett Esophagus | 8 |
| The MetroHealth System | AV Block, COVID-19, Coronavirus Infections | 8 |
| University Hospitals Cleveland | 1st Line NSCLC, Abdominal Aortic Aneurysm, Advanced Solid Tumor | 8 |
| University Hospitals of Cleveland | Advanced Solid Tumors, Aortic Aneurysm, Aortic Dissection | 8 |
| Cleveland Clinic - Cleveland | Antibody-Mediated Rejection (AMR), Myelodysplastic Syndromes, SBS Associated With Intestinal Failure (SBS-IF) | 8 |
| Cleveland Clinic Fairview Hospital | HPV Infection, Pre-Cancerous Dysplasia, Bleeding | 7 |
| Louis Stokes Cleveland VA Medical Center | Multiple Sclerosis, Stroke, Adenocarcinoma of the Colon | 7 |
| MetroHealth | Acute Kidney Injury, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 7 |
Active & Upcoming Studies in Cleveland (2026)
Recruiting trials in Cleveland grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (376 active studies)
- TRANScriptional Pathways Of Surgical Pain Modulated by Music Therapy Exposure (TRANSPOSE) · Case Comprehensive Cancer Center
- A Study to Evaluate Adverse Events and Change in Disease Activity With Injected Etentamig Plus Oral Pomalidomide Versus Standard Therapies in Adults With Relapsed or Refractory Multiple Myeloma · Phase 3 · AbbVie
Cardiovascular (104 active studies)
- Metabolic Surgery for Atrial Fibrillation Elimination · Phase 4 · Ali Aminian
- Novel Technologies to Improve Echocardiographic Estimates of Left Ventricular Filling Pressure in Heart Failure Combined With Atrial Fibrillation · Oslo University Hospital
Neurology & pain (87 active studies)
- REstoring Flow by REvascularization With Submaximal Angioplasty in Hemodynamic IntraCranial Atherosclerotic Stenosis · Case Western Reserve University
- A Study of Remibrutinib Using MR Imaging in Relapsing or Progressive MS · Phase 2 · Moein Amin
Diabetes & metabolic (36 active studies)
- Whole Gut Motility Abnormalities Following GLP-1 Receptor Agonist (GLP-1RA) Initiation · The Cleveland Clinic
- PNS to Improve Vascular Function and Limb Health in Veterans · VA Office of Research and Development
Eye & vision (17 active studies)
- Study of Serine Supplementation to Protect Vision in MacTel · Phase 3 · The Lowy Medical Research Institute Limited
- Noninvasive Imaging Biomarkers of Treatable Macrovascular Disease in Age-related Macular Degeneration. · Scott Raymond
Mental health & behavior (16 active studies)
- Neural Correlates of Suicidal Behavior in Youth · The Cleveland Clinic
- Reduction of Anxiety Through Dual Treatment: Digital CBT & NBHWC Coaching · Toivoa Inc
Pediatric (16 active studies)
- A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction · Phase 3 · Bayer
- Humidity Asthma Interventions for Low Socioeconomic Status Children · Case Western Reserve University
HIV / STI (6 active studies)
- Dasatinib for HIV-1 Reservoir Reduction · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- Menopausal HT for Women Living With HIV (HoT) · Phase 4 · Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Vaccines (5 active studies)
- A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Given to Healthy Children 4 to 6 Years of Age · Phase 3 · GlaxoSmithKline
- A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Severe Disease · Phase 2 · Shionogi
Common conditions studied in Cleveland
- Heart Failure (29 active studies)
- Advanced Solid Tumor (19 active studies)
- Breast Cancer (19 active studies)
- Cardiovascular Diseases (17 active studies)
- Prostate Cancer (16 active studies)
- Coronary Artery Disease (15 active studies)
Leading research sponsors in Cleveland
- The Cleveland Clinic
- Case Comprehensive Cancer Center
- University Hospitals Cleveland Medical Center
- National Cancer Institute (NCI)
- Case Western Reserve University
Frequently asked questions
How many paid clinical trials are currently recruiting in Cleveland?
There are approximately 1,266 recruiting clinical trials in Cleveland, Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Cleveland pay participants?
Most recruiting trials in Cleveland compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Cleveland?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Cleveland?
The most common conditions under active study in Cleveland include Heart Failure (29), Advanced Solid Tumor (19), Breast Cancer (19), Cardiovascular Diseases (17), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Cleveland?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Cleveland on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Cleveland?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Cleveland?
Recruiting research sites in Cleveland include Cleveland Clinic, University Hospitals Cleveland Medical Center, Cleveland Clinic Foundation, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Cleveland right now?
The largest active categories in Cleveland are Cancer & tumors (376), Cardiovascular (104), Neurology & pain (87). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.