Ultra Processed Foods Consumption and Impact in Rheumatic Diseases.

Sponsor
Hospices Civils de Lyon
Study ID
NCT06776965
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Dietary Questionnaire — OTHER
    Self administered dietary questionnaire at baseline, 6 and 12 months.
  • Evaluation of disease activity (DAS-28, ASDAS, EVA, number of swollen joints, number of painful joint, nocturnal pain, morning stiffness) — OTHER
    Self administered questionnaire of disease activity at baseline, 6 and 12 months.

Study Details

Ultra-processed foods (UPF) represent one of the mainstays of today's diet. They are defined by the NOVA classification system. It was demonstrated that UPF consumption was associated with activity of inflammatory bowel diseases with underlying mechanisms not fully identified yet. It is suspected that UPF constituents could modify the gut microbiota, increase intestinal barrier permeability and directly engage immune surveillance systems, effects that could individually or synergistically increase the risk of immunomediated diseases. As some pathophysiological mechanisms are shared among IBD and rheumatic diseases, we have wondered if UPF consumption could be associated with increased risk of rheumatic disease and/or with their activity. Our primary aim will be to study the pattern of UPF consumption in patients with rheumatic diseases. Our secondary objectives will be to study the activity of diseases according to UPF consumption.

Key Dates

First listed
Jan 15, 2025
Start date
Mar 31, 2025
Status verified
Apr 2025
Primary completion
Mar 31, 2026
Completion
Nov 30, 2026

Study Design

Enrollment
240 participants (estimated)

Arms

  • Arm: Rheumatoid Arthritis
    Patients in the first group will correspond to those with rheumatoid arthritis according to ACR criteria of RA
  • Arm: Spondyloarthritis
    Patients in the second group will correspond to those with spondyloarthritis according ASDAS criteria
  • Arm: Osteoarthritis
    Patients in the third group will correspond to those with spondyloarthritis according ACR criteria
  • Arm: Controls
    Patients without rheumatic disease

Primary Outcome Measure

Describe the consumption of ultra-processed foods in patients with chronic inflammatory rheumatism [ Time Frame: At baseline ]

Central Contacts

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