Home-based Vision Rehabilitation Guided by Brain Imaging

Part of paid clinical trials in Washington D.C., District of Columbia.

Sponsor
Georgetown University
Study ID
NCT07635329
Status
Recruiting
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Conditions

  • Brain Tumor
  • Cortical Blindness
  • Hemianopia Homonymous
  • Quadrantanopia
  • Stroke
  • Traumatic Brain Injury
  • Visual Field Defect
  • Visual Field Defect, Peripheral
  • Visual Field Loss

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • High-level perceptual learning-based training — BEHAVIORAL
    Behavioral intervention consisting of repeated computerized visual discrimination tasks targeting higher-order visual processing
  • Low-level perceptual learning-based training — BEHAVIORAL
    behavioral intervention consisting of repeated computerized visual discrimination tasks targeting low-level visual processing

Study Details

The BRIGHT (Behavioral Rehabilitation Through Image-Guided Home-based Training) study aims to evaluate the effectiveness of image-guided, home-based perceptual training at improving visual performance in individuals with visual field loss. Using a prospective, crossover design, BRIGHT combines visual behavioral testing, neuroimaging, and a home-based intervention. It aims to 1) identify neural pathways that support training-induced visual plasticity; and 2) compare the efficacy of different types of visual training delivered in a home-based setting.

Key Dates

Start date
Jul 1, 2026
Status verified
Jun 2026
Primary completion
Mar 31, 2030
Completion
Mar 31, 2030

Study Design

Enrollment
100 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT

Arms

  • Experimental: Perceptual learning-based training using high-level visual stimuli
    A 3 week at-home online perceptual learning-based training using high-level visual stimuli.
  • Active Comparator: Perceptual learning-based training using low-level visual stimuli
    A 3 week at-home online perceptual learning-based training using low-level visual stimuli.

Primary Outcome Measure

Change in high-level perceptual discrimination performance [ Time Frame: Week 2-4 or Week 7-9 of the study (depending on the order) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Georgetown University Medical CenterWashington D.C.District of Columbia20057
Tina Liu, PhD
[email protected]
202-784-9949
Tina Liu, PhD (PRINCIPAL_INVESTIGATOR)

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