Essential tremor Clinical Trials

Recruiting essential tremor studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat essential tremor. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting essential tremor studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting essential tremor trials

Within

Cerebellar Research in Ultrasound Stimulation

for Essential Tremor

Sponsor: KU Leuven

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07508696

Transcranial Temporal Interference Stimulation (tTIS) To Modulate Essential Tremor

for Essential Tremor

Sponsor: University Hospital, Geneva

Sex: All·Age: 18+

Code: NCT07531238

Open Label Study for the Use of Low Intensity Focused Ultrasound for Essential Tremor

for Essential Tremor

1 site in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 90

Code: NCT07599592·EARLY_Phase 1

Apply to this trial

Image-Guided DBS Programming

for Essential Tremor

1 site in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 21 - 85

Code: NCT07433699·Phase 1

Neuromodulation Strategies for Treatment-Resistant Essential Tremor Using Chronos™ DBS

for Essential Tremor

Sponsor: University of British Columbia

Sex: All·Age: 19 - 85

Code: NCT07302867

Analysis of Cutaneous Phosphorylated Alpha-Synuclein to Identify Patients at Risk of Progressing From Essential Tremor to Parkinson's Disease

for Essential Tremor, Movement Disorders

2 sites incl. Scottsdale

Sponsor: CND Life Sciences

Sex: All·Age: 50 - 85

Code: NCT07428447

Apply to this trial

Investigating Subcortical Contributions to Speech Sequencing in Deep Brain Stimulator Recipients

for Parkinson's Disease (PD)

2 sites in Boston

Sponsor: Boston University Charles River Campus

Sex: All·Age: 18+

Code: NCT07455760

Apply to this trial

Magnetoencephalography (MEG) Pilot Study

for Essential Tremor

1 site in Gainesville

Sponsor: University of Florida

Sex: All·Age: 50 - 84

Code: NCT07446192

Apply to this trial

Deep Brain Stimulation of the Deep Cerebellar Nuclei for Refractory Tremor

for Tremor

1 site in Cleveland

Sponsor: The Cleveland Clinic

Sex: All·Age: 21+

Code: NCT07049003·Phase 1

Apply to this trial

Dual-Site Transcranial Magnetic Stimulation of the Supplementary Motor Area and Cerebellum for the Treatment of Essential Tremor.

for Essential Tremor

Sponsor: São Paulo State University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07344194·Phase 1, Phase 2

Apply to this trial

LIFUS For Neurological Disorders

for Parkinson's Disease (PD)

Sponsor: University Health Network, Toronto

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT07417280

Apply to this trial

Analysis of Clinical Outcomes in Patients Undergoing Magnetic Resonance-Guided Focused Ultrasound for Medication-Refractory Tremor

for Essential Tremor

Sponsor: Sunnybrook Health Sciences Centre

Sex: All·Age: 22+

Code: NCT07212244

Apply to this trial

Attention and Eye Movement in Parkinson's Disease

for Essential Tremor

1 site in Omaha

Sponsor: University of Nebraska

Sex: All·Age: 19 - 90·Accepts healthy volunteers

Code: NCT06899022

Apply to this trial

Proof of Concept Study on BP1.4979 Effect on Essential Tremor

for Essential Tremor

Sponsor: Bioprojet

Sex: All·Age: 18 - 85

Code: NCT07074002·Phase 2

Apply to this trial

Developing a New LIFU Neuromodulation Method to Suppress Tremor

for Essential Tremor

Sponsor: University of Calgary

Sex: All·Age: 18+

Code: NCT07103265·Phase 2

GyroGlove Use in Essential Tremor Patients

for Essential Tremor

3 sites incl. Farmington Hills

Sponsor: GyroGear Ltd

Sex: All·Age: 18+

Code: NCT05958030

Simultaneous Bilateral Radiofrequency Thalamotomy for Medication-Refractory Essential Tremor

for Essential Tremor

Sponsor: Tokyo Women's Medical University

Sex: All·Age: 20 - 70

Code: NCT07066358

Apply to this trial

Modulate Tremor Severity With Low-intensity Focused Ultrasound Stimulation Targeting the Deep Nucleus of Patients With Refractory Hand Tremor.

for Parkinson Disease (PD)

Sponsor: National Taiwan University Hospital

Sex: All·Age: 18 - 80

Code: NCT07172295

Apply to this trial

Safety and Effectiveness of Unilateral MR-Guided Focused Ultrasound Thalamotomy for Essential Tremor

for Essential Tremor

Sponsor: meishanshan

Sex: All·Age: 22+

Code: NCT07006740

Temporal Interference for Essential Tremor

for Essential Tremor

Sponsor: Liankun_Ren

Sex: All·Age: 30 - 70

Code: NCT07016425

Apply to this trial

Circadian Adaptive DBS in Essential Tremor

for Essential Tremor

1 site in Gainesville

Sponsor: University of Florida

Sex: All·Age: 21 - 89

Code: NCT06635811

Apply to this trial

EMBRACE Tremor BiFUS

for Essential Tremor

Sponsor: InSightec

Sex: All·Age: 18+

Code: NCT06974916

Apply to this trial

The Efficacy of Aldehyde Dehydrogenase Enzyme in Essential Tremor Patients: A Single-Center Study

for Essential Tremor

Sponsor: Pico Entech Co., Ltd.

Sex: All·Age: 18+

Code: NCT07238725

Home Use Study of Targeted Mechanical Stimulation for Tremor Relief

for Essential Tremor

1 site in Cambridge

Sponsor: Encora, Inc.

Sex: All·Age: 18+

Code: NCT07078422

Apply to this trial

Stereotactic Radiosurgery in the Treatment of Essential Tremor

for Essential Tremor

Sponsor: Maria Sklodowska-Curie National Research Institute of Oncology

Sex: All·Age: 50+

Code: NCT06821906·Phase 2

Apply to this trial

Ultrasound Neuromodulation in Essential Tremor

for Essential Tremor

1 site in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06610877

Apply to this trial

A Study to Evaluate the Safety and Efficacy of Staged Bilateral Magnetic Resonance-Guided Focused Ultrasound Thalamotomy for the Treatment of Essential Tremor

for Essential Tremor

Sponsor: Chinese PLA General Hospital

Sex: All·Age: 22+

Code: NCT06676501

Possibilities of Use MRI-Guided Laser Interstitial Thermal Therapy in Medically Intractable Tremor

for Laser Interstitial Thermal Therapy

Sponsor: Centre Hospitalier Universitaire, Amiens

Sex: All·Age: 18+

Code: NCT06799923

Apply to this trial

24-months Study to Evaluate Safety and Efficacy of Peroneal Transcutaneous NeuroModulation in Subjects With Parkinson's Disease and Essential Tremor

for Parkinson Disease

Sponsor: Stimvia s.r.o.

Sex: All·Age: 18+

Code: NCT06570421

Apply to this trial

Directional Bilateral Thalamic Patterned Stimulation (Chronos)

for Essential Tremor

Sponsor: Alfonso Fasano

Sex: All·Age: 18 - 85

Code: NCT06325852

Apply to this trial

Tapping Test and the Archimedean Spiral for the Differential Diagnosis of Tremor. Machine Learning Approach

for Tremor

Sponsor: Consorci Sanitari de l'Alt Penedès i Garraf

Sex: All·Age: 45 - 79

Code: NCT06378619

Apply to this trial

The BRAINMAP-DBS Study: BRain Network AnalysIs usiNg 7-Tesla MRI and MAgnetoencephalograPhy for Deep Brain Stimulation

for Deep Brain Stimulation

Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Sex: All·Age: 18+

Code: NCT06932692

Apply to this trial

Lesioning Procedures for Movement Disorders

for Dystonia

Sponsor: All India Institute of Medical Sciences

Sex: All·Age: All ages

Code: NCT06352268

Identifying Markers of Disease Subtypes and Disease Progression in the Syndrome of Essential Tremor

for Essential Tremor

Sponsor: Medical University of Graz

Sex: All·Age: 18+

Code: NCT06349538

Functional Brain Network Changes in Patients Undergoing Deep Brain Stimulation for Essential Tremor

for Essential Tremor

1 site in Cleveland

Sponsor: The Cleveland Clinic

Sex: All·Age: 30 - 80·Accepts healthy volunteers

Code: NCT06293638

Apply to this trial

3-D Tractography FUS Ablation for Essential Tremor

for Essential Tremor

1 site in Chapel Hill

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 22+

Code: NCT06331052

Apply to this trial

Multicentre RCT of Awake Versus Asleep Tractography Based DBS for ET

for Essential Tremor

Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Sex: All·Age: 18+

Code: NCT05968976

Apply to this trial

Radiofrequency (RF) Ablation Prospective Outcomes Study for Central Nervous System - RAPID for CNS

for Parkinson Disease

Sponsor: Boston Scientific Corporation

Sex: All·Age: All ages

Code: NCT06553625

Apply to this trial

Closed-loop TMS for Tremor

for Essential Tremor

Sponsor: University of Oxford

Sex: All·Age: 18+

Code: NCT07574164

Apply to this trial

Repetitive Transcranial Magnetic Stimulation Therapy in Essential Tremor

for Essential Tremor

Sponsor: Second Affiliated Hospital of Soochow University

Sex: All·Age: 18 - 80

Code: NCT06145932

Apply to this trial

Coordinated Reset Deep Brain Stimulation for Essential Tremor

for Essential Tremor

1 site in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21+

Code: NCT05897775·Phase 1

Apply to this trial

A Study of Wearable Device in Essential Tremor Patients

for Essential Tremor

1 site in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT05976074

The STEREO-DBS ET Study: 7-Tesla MRI Brain Network Analysis for Deep Brain Stimulation in Essential Tremor

for Essential Tremor

Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Sex: All·Age: 18+

Code: NCT05909839

Apply to this trial

Electroclinical Correlates in Essential Tremor

for Essential Tremor

Sponsor: University Hospital, Bordeaux

Sex: All·Age: 18 - 75

Code: NCT05671848

Apply to this trial

Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia

for Dystonia

1 site in Boston

Sponsor: Massachusetts Eye and Ear Infirmary

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT05317390

Apply to this trial

Motor Network Physiology

for Parkinson Disease

1 site in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 89

Code: NCT04957095

Apply to this trial

Elucidating the Temporality of Structural and Functional Connectivity Changes in Essential Tremor After Successful Deep Brain Stimulation to the Dentato-rubro-thalamic Tract

for Essential Tremor

1 site in Manhasset

Sponsor: Northwell Health

Sex: All·Age: 18 - 85

Code: NCT04758624

Apply to this trial

Neurofeedback Using Implanted Deep Brain Stimulation Electrodes

for Parkinson Disease

Sponsor: ETH Zurich

Sex: All·Age: 18+

Code: NCT05101161

Apply to this trial

Bilateral Essential Tremor Treatment With Gamma Knife

for Essential Tremor

Sponsor: Université de Sherbrooke

Sex: All·Age: 18+

Code: NCT04748640·Phase 2, Phase 3

Apply to this trial

Directional Versus Nondirectional DBS for ET

for Essential Tremor

1 site in Portland

Sponsor: Oregon Health and Science University

Sex: All·Age: 18 - 80

Code: NCT04828798

Apply to this trial

Cortical-Basal Ganglia Speech Networks

for Parkinson Disease

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 85

Code: NCT04286308

Apply to this trial

Dual Lead Thalamic Deep Brain Recording (DBR)-DBS Interface for Closed Loop Control of Severe Essential Tremor

for Essential Tremor

1 site in Gainesville

Sponsor: University of Florida

Sex: All·Age: 21 - 99·Accepts healthy volunteers

Code: NCT04212780

Apply to this trial

Abbott DBS Post-Market Study of Outcomes for Indications Over Time

for Movement Disorders

8 sites incl. Tampa

Sponsor: Abbott Medical Devices

Sex: All·Age: All ages

Code: NCT04071847

Apply to this trial

Boston Scientific Registry of Deep Brain Stimulation for Treatment of Essential Tremor (ET)

for Essential Tremor

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT04032470

Apply to this trial

Algorithms for Programming DBS Systems for ET

for Essential Tremor

1 site in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 21+

Code: NCT03984643

Apply to this trial

Deep Brain Stimulation (DBS) Retrospective Outcomes Study

for Parkinson Disease

8 sites incl. Phoenix

Sponsor: Boston Scientific Corporation

Sex: All·Age: All ages

Code: NCT03664609

Apply to this trial

Chinese ET Registry (CETR)

for Essential Tremor

Sponsor: Xiangya Hospital of Central South University

Sex: All·Age: All ages

Code: NCT04198246

Apply to this trial

The Swedish Essential Tremor (SWEET) Trial

for Essential Tremor

Sponsor: Karolinska Institutet

Sex: All·Age: 18 - 75

Code: NCT03832712

Apply to this trial

Effects of Stimulation Patterns of Deep Brain Stimulation

for Parkinson Disease

3 sites incl. Gainesville

Sponsor: Duke University

Sex: All·Age: 21 - 80

Code: NCT02553525

Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor

for Tremor

1 site in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT01734122

Apply to this trial

Essential tremor clinical trials — common questions

Are essential tremor clinical trials free to join?

Yes. Participating in a essential tremor clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a essential tremor clinical trial?

Each essential tremor study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a essential tremor trial near me?

Use the location controls above. We'll show recruiting essential tremor trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many essential tremor trials are recruiting right now?

We're currently tracking roughly 30 recruiting essential tremor trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Essential tremor trials by city

Gainesville, FL Boston, MA Cleveland, OH Farmington Hills, MI Los Angeles, CA Omaha, NE Portland, OR San Francisco, CA Tampa, FL

Related specialties

Neurology Brain disorders