Multiple system atrophy Clinical Trials

Recruiting multiple system atrophy studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat multiple system atrophy. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting multiple system atrophy studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting multiple system atrophy trials

Within

High-Altitude Neurodegeneration Cohort (HANC) Study

for Multiple System Atrophy

Sponsor: West China Hospital

Sex: All·Age: 40 - 75·Accepts healthy volunteers

Code: NCT07657520

Apply to this trial

Early Molecular Biomarkers for Differentiating Parkinsonian Syndromes

for PARKINSON DISEASE (Disorder)

Sponsor: International Institute of Molecular and Cell Biology in Warsaw

Sex: All·Age: 40 - 80·Accepts healthy volunteers

Code: NCT07604883

Expansion Study of ALT001 in Patients With Multiple System Atrophy

for Multiple System Atrophy

Sponsor: yilong Wang

Sex: All·Age: 30 - 75

Code: NCT07476352·EARLY_Phase 1

Efficacy and Safety of Butylphthalide in the Treatment of Multiple System Atrophy

for Multiple System Atrophy

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

Sex: All·Age: 30 - 80

Code: NCT07518810·Phase 2, Phase 3

Individualized Transcranial Magnetic Stimulation in Parkinsonian Disorders

for Parkinson's Disease

Sponsor: Peking University First Hospital

Sex: All·Age: 30 - 80

Code: NCT07570212

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An Extension Trial to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy

for Multiple System Atrophy

6 sites incl. La Jolla

Sponsor: Teva Branded Pharmaceutical Products R&D LLC

Sex: All·Age: 30+

Code: NCT07197866·Phase 2

Apply to this trial

hUC-MSC-sEV-001 Nasal Drops for Neurodegenerative Diseases

for Alzheimer Disease

Sponsor: Xuanwu Hospital, Beijing

Sex: All·Age: 18 - 80

Code: NCT06607900·Phase 1

Efficacy and Safety of Bilateral Cervical Lymphatic-Venous Anastomosis in the Treatment of Multiple System Atrophy

for Multiple System Atrophy

Sponsor: Ruijin Hospital

Sex: All·Age: 40 - 70

Code: NCT07036939

Prospective Multicenter Registry Study of Multiple System Atrophy in China

for Multiple System Atrophy

Sponsor: Peking University First Hospital

Sex: All·Age: 40 - 75·Accepts healthy volunteers

Code: NCT07644013

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A Phase 2a Study of Foralumab Nasal in Patients With Multiple System Atrophy (MSA)

for Multiple System Atrophy

1 site in Boston

Sponsor: Tiziana Life Sciences LTD

Sex: All·Age: 30 - 85

Code: NCT06868628·Phase 2

Apply to this trial

Shanghai Clinical Cohort - Parkinson's Disease (Reserve)

for Parkinson's Disease (PD)

Sponsor: Ruijin Hospital

Sex: All·Age: All ages

Code: NCT07353463

Apply to this trial

A Phase 2 Study of YA-101 in Patients With Multiple System Atrophy

for Multiple System Atrophy

6 sites incl. Los Angeles

Sponsor: Dasher Neuroscience Inc.

Sex: All·Age: 30+

Code: NCT06848231·Phase 2

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Autologous suraL nervE Grafting to the Substantia nigrA in Patients With Synuclienopathies

for Multiple System Atrophy

1 site in Lexington

Sponsor: Craig van Horne, MD, PhD

Sex: All·Age: 40 - 75

Code: NCT06683365·Phase 1

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The CurePSP Genetics Program

for PSP

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 35+·Accepts healthy volunteers

Code: NCT06647641

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A Trial to Test if TEV-56286 is Effective for Treatment of Participants With Multiple System Atrophy

for Multiple System Atrophy

15 sites incl. La Jolla

Sponsor: Teva Branded Pharmaceutical Products R&D LLC

Sex: All·Age: 30 - 75

Code: NCT06568237·Phase 2

Apply to this trial

Parkinson Atypical Rating of Oculometric Patterns Evaluated Routinely

for Parkinson Disease

Sponsor: NeuraLight

Sex: All·Age: 30 - 80·Accepts healthy volunteers

Code: NCT06597071

Neurodegenerative Diseases Progression Markers (MARKERS-NDD)

for Neurodegenerative Diseases

Sponsor: Casa di Cura San Raffaele Cassino

Sex: All·Age: 10+

Code: NCT06596746

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Prodromal Model of Parkinson's Disease Confined to The Peripheral Nervous System

for Polyneuropathy

Sponsor: University of Aarhus

Sex: All·Age: 18 - 85

Code: NCT06745011

PET Imaging Evaluation of [11C]SY08

for Parkinson's Disease

1 site in Charlestown

Sponsor: Massachusetts General Hospital

Sex: All·Age: 50 - 80·Accepts healthy volunteers

Code: NCT06098612·EARLY_Phase 1

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The Use of the CUE1/CUE1+ in People With Parkinson's Disease and Related Disorders

for Parkinson's Disease and Parkinsonism

Sponsor: Queen Mary University of London

Sex: All·Age: 18+

Code: NCT06174948

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The NADAPT Study: a Randomized Double-blind Trial of NAD Replenishment Therapy for Atypical Parkinsonism

for Progressive Supranuclear Palsy

Sponsor: Haukeland University Hospital

Sex: All·Age: 30 - 85

Code: NCT06162013·Phase 2

Apply to this trial

Medical Decision Making in Multiple System Atrophy

for Multiple System Atrophy

Sponsor: Medical University Innsbruck

Sex: All·Age: 30+

Code: NCT06072105

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Study on Artificial Intelligence-Based Facial and Speech-Related Patterns in Parkinson's Disease and Their Digital Biomarkers

for Parkinson's Disease

Sponsor: Beijing Tiantan Hospital

Sex: All·Age: 15 - 75·Accepts healthy volunteers

Code: NCT07392411

Apply to this trial

NYSCF Scientific Discovery Biobank

for ALS

1 site in New York

Sponsor: New York Stem Cell Foundation Research Institute

Sex: All·Age: 30 Days+

Code: NCT06203106

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Utilisation of Health Services and Quality of Life in Patients With Atypical Parkinsonian Syndromes

for Progressive Supranuclear Palsy

Sponsor: University Hospital Southampton NHS Foundation Trust

Sex: All·Age: 18+

Code: NCT06645626

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North American Prodromal Synucleinopathy Consortium Stage 2

for REM Sleep Behavior Disorder

8 sites incl. Los Angeles

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05826457

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ION464 Administered to Adults With Multiple System Atrophy (HORIZON)

for Multiple System Atrophy

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: All·Age: 40 - 70

Code: NCT04165486·Phase 1

Apply to this trial

CPAP for the Treatment of Supine Hypertension

for Autonomic Failure

1 site in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 40 - 80

Code: NCT05489575

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Synaptic Loss in Multiple System Atrophy

for Multiple System Atrophy

Sponsor: University of Exeter

Sex: All·Age: 45 - 80

Code: NCT05121012

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Comprehensive Swallowing Rehabilitation in Patients With MSA

for Multiple System Atrophy

Sponsor: Seoul National University Hospital

Sex: All·Age: 19+

Code: NCT04782284

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Use of Accelerometer for Quantification of Neurogenic Orthostatic Hypotension Symptoms

for Orthostatic

1 site in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 40 - 80

Code: NCT04782830

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Insulin Resistance in Multiple System Atrophy

for Multiple System Atrophy

Sponsor: University Hospital, Bordeaux

Sex: All·Age: 30+·Accepts healthy volunteers

Code: NCT04250493

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[18F]F-DOPA Imaging in Patients With Autonomic Failure

for Autonomic Failure

1 site in Nashville

Sponsor: Daniel Claassen

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04246437·Phase 1

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Pain and Autonomic Symptoms in Parkinson's Disease and Atypical Parkinsonisms

for Parkinson Disease

Sponsor: Istituti Clinici Scientifici Maugeri SpA

Sex: All·Age: 18+

Code: NCT05748028

Apply to this trial

Facilitating Diagnostics and Prognostics of Parkinsonian Syndromes Using Neuroimaging

for Parkinson Disease

1 site in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT03872102

Apply to this trial

North American Prodromal Synucleinopathy Consortium

for REM Sleep Behavior Disorder

9 sites incl. Sun City

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT03623672

Systematic Assessment of Laryngopharyngeal Function in Patients With Neurodegenerative Diseases

for Multiple System Atrophy

Sponsor: Kliniken Beelitz GmbH

Sex: All·Age: 18+

Code: NCT04706234

Apply to this trial

The Swedish BioFINDER 2 Study

for Dementia

Sponsor: Skane University Hospital

Sex: All·Age: 20 - 100·Accepts healthy volunteers

Code: NCT03174938

Apply to this trial

Overnight Trials With Heat Stress in Autonomic Failure Patients With Supine Hypertension

for Hypertension

1 site in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 80

Code: NCT03042988

Apply to this trial

Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure

for Autonomic Failure

1 site in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 40 - 80

Code: NCT02897063·Phase 1

Apply to this trial

Natural History Study of Synucleinopathies

for Patients With Synucleinopathies

5 sites incl. Boston

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT01799915

Apply to this trial

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

for Rare Disorders

1 site in Sioux Falls

Sponsor: Sanford Health

Sex: All·Age: All ages

Code: NCT01793168

Apply to this trial

Cerebro Spinal Fluid Collection (CSF)

for Alzheimer Disease

Sponsor: University Hospital, Strasbourg, France

Sex: All·Age: All ages

Code: NCT04844060

Apply to this trial

Multiple system atrophy clinical trials — common questions

Are multiple system atrophy clinical trials free to join?

Yes. Participating in a multiple system atrophy clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a multiple system atrophy clinical trial?

Each multiple system atrophy study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a multiple system atrophy trial near me?

Use the location controls above. We'll show recruiting multiple system atrophy trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many multiple system atrophy trials are recruiting right now?

We're currently tracking roughly 22 recruiting multiple system atrophy trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Multiple system atrophy trials by city

Boston, MA La Jolla, CA Los Angeles, CA

Related specialties

Neurology