Neuroblastoma Clinical Trials

Recruiting neuroblastoma studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat neuroblastoma. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting neuroblastoma studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting neuroblastoma trials

Within

NANT 2021-02: Randomized MIBG With Vorinostat/Dinutuximab/Vorinostat + Dinutuximab

for Neuroblastoma

13 sites incl. Los Angeles

Sponsor: New Approaches to Neuroblastoma Therapy Consortium

Sex: All·Age: 1 - 30

Code: NCT07261241·Phase 2

Haploidentical Donor Cytokine-Induced Memory-Like Natural Killer Cells (CIML-NK) for Relapsed & Refractory Neuroblastoma

for Neuroblastoma

1 site in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 1 - 39

Code: NCT07635056·Phase 2

Apply to this trial

B7-H3.CD28Z.CART in Solid Tumors

for Pediatric Solid Tumor

1 site in Boston

Sponsor: Robbie Majzner

Sex: All·Age: 9 Months - 30

Code: NCT07358260·Phase 1

4SCAR-T Therapy Targeting GD2, PSMA and CD276 for Treating Neuroblastoma

for Neuroblastoma

Sponsor: Shenzhen Geno-Immune Medical Institute

Sex: All·Age: 1 - 65

Code: NCT04637503·Phase 1, Phase 2

Apply to this trial

Phase I Study of Becotatug Vedotin for Safety and Efficacy in EGFR-Positive Pediatric Relapsed/Refractory or Metastatic Solid Tumors

for Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M)

Sponsor: Sun Yat-sen University

Sex: All·Age: 2 - 18

Code: NCT07584499·Phase 1

Apply to this trial

Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

for Atypical Teratoid/Rhabdoid Tumor

12 sites incl. Birmingham

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: Up to 26

Code: NCT06465199·Phase 1, Phase 2

Apply to this trial

Phase I Clinical Trial of ThINKK Adoptive Immunotherapy After Allogeneic Hematopoietic Transplantation in Children With Leukemia or Neuroblastoma

for Leukaemia (Acute Lymphoblastic)

Sponsor: Michel Duval

Sex: All·Age: 2 - 12

Code: NCT07518654·Phase 1

Comparison of 18F Labeled Analog of MIBG (18F-MFBG) PET/CT and 123I-MIBG SPECT in Pediatric Patients With Neuroblastoma.

for Neuroblastoma

Sponsor: Institut Curie

Sex: All·Age: 365 Days - 17

Code: NCT07111117·Phase 2

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

for Neuroblastoma

1 site in Gainesville

Sponsor: University of Florida

Sex: All·Age: 6 Months - 25

Code: NCT06625190·Phase 1, Phase 2

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Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE)

for Rhabdomyosarcoma

2 sites in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 1 - 23

Code: NCT07172958·Phase 1

Apply to this trial

An Imaging Study of Anti-GD2-800CW in Patients With Neuroblastoma

for Neuroblastoma

Sponsor: Princess Maxima Center for Pediatric Oncology

Sex: All·Age: 1 - 18

Code: NCT07399821·Phase 1, Phase 2

Apply to this trial

Interest of Preoperative Arteriography to Identify the Adamkiewicz Artery Before Surgery for Basi-thoracic Neuroblastic Tumors

for Tumor, Solid

Sponsor: Assistance Publique - Hôpitaux de Paris

Sex: All·Age: Up to 18

Code: NCT06798532

Phase I Trial of rhIL-15 Plus Dinutuximab Plus Irinotecan/Temozolomide for Children and Young Adults With Relapsed/Refractory Neuroblastoma

for Neuroblastoma

1 site in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 3 - 35

Code: NCT06995872·Phase 1

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Comparison of NeuroEXPLORER PET/CT Versus Standard-of-care PET/CT of the Head and Neck Region.

for Dementia

Sponsor: prof. dr. Koen Van Laere

Sex: All·Age: 28 Days+·Accepts healthy volunteers

Code: NCT07595666

Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation

for CNS Embryonal Tumor

Sponsor: C17 Council

Sex: All·Age: Up to 6

Code: NCT06942039·EARLY_Phase 1

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GSL Synthetase Inhibitor Plus GM-CSF and/ or Immune Checkpoint Inhibitor in Previously Treated High-Risk Neuroblastoma.

for Neuroblastoma

Sponsor: Chinese PLA General Hospital

Sex: All·Age: 6 - 12

Code: NCT07090538·EARLY_Phase 1

Safety & Efficacy of IR-101 in Relapsed/Refractory Neuroblastoma

for Neuroblastoma

Sponsor: Sichuan University

Sex: All·Age: 12 Months+

Code: NCT07067346·EARLY_Phase 1

Apply to this trial

Feasibility Study of Prolonged Administration of Naxitamab, Irinotecan, and Temozolomide for Patients With Relapsed or Refractory Neuroblastoma

for Neuroblastoma

2 sites in Boston

Sponsor: Steven DuBois, MD

Sex: All·Age: 1 - 30

Code: NCT07027748·Phase 1

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Arsenic Trioxide With MAPK Inhibitors and Chemotherapy for Stage 4/M Neuroblastoma

for Neuroblastoma

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Sex: All·Age: 18 Months - 18

Code: NCT06933394·Phase 2

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A Clinical Trial on Autologous NK Cells Combined With GD2 Monoclonal Antibody in the Treatment of Children With Newly Diagnosed High-risk or Relapsed/Refractory Neuroblastoma

for Neuroblastoma

Sponsor: Guangzhou Women and Children's Medical Center

Sex: All·Age: 1 - 18

Code: NCT06948994·Phase 1, Phase 2

Resource Intervention to Support Equity (RISE) in High-Risk Neuroblastoma

for Neuroblastoma

6 sites incl. Hartford

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: Up to 17

Code: NCT06831552

Apply to this trial

18F-mFBG PET Imaging in the Evaluation of Neuroblastoma

for Neuroblastoma

Sponsor: First Affiliated Hospital of Zhejiang University

Sex: All·Age: Up to 18

Code: NCT06852807

Apply to this trial

Accurate Diagnosis and Grading of Pediatric Solid Tumors Based on Pathological Large Models

for Neuroblastoma

Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

Sex: All·Age: 0 - 18

Code: NCT06822842

Fertility Preservation in Children With Solid Tumors: Detection of Residual Disease by a Sensitive Method

for Neuroblastoma

Sponsor: University Hospital, Clermont-Ferrand

Sex: All·Age: 2 - 45

Code: NCT07141862

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Study Combining Dinutuximab Beta With Two Chemotherapy Regimens in Neuroblastoma

for Neuroblastoma

Sponsor: Princess Maxima Center for Pediatric Oncology

Sex: All·Age: 18 Months - 18

Code: NCT06485947·Phase 1

Apply to this trial

Biomarkers of Resiliency In Childhood Cancer Surgery

for Pediatric Cancer

1 site in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 3 - 25

Code: NCT06674811

Apply to this trial

Clinical Application of Somatostatin Receptor and Norepinephrine Transporter Targeted Imaging for Diagnosis and Staging of Neuroblastoma and Pheochromocytoma/Paraganglioma

for Neuroblastoma

Sponsor: Nanjing First Hospital, Nanjing Medical University

Sex: All·Age: 6 Months+

Code: NCT07195500

Apply to this trial

NANT 2021-01 Phase II STING (Sequential Temozolomide, Irinotecan, NK Cells and GD2 mAb) Trial

for Neuroblastoma

13 sites incl. Los Angeles

Sponsor: New Approaches to Neuroblastoma Therapy Consortium

Sex: All·Age: 1 - 31

Code: NCT06450041·Phase 2

Apply to this trial

Tipifarnib and Naxitamab for Relapsed/Refractory Neuroblastoma

for Neuroblastoma

12 sites incl. Little Rock

Sponsor: Giselle Sholler

Sex: All·Age: 1 - 21

Code: NCT06540963·Phase 2

Apply to this trial

A Study on the Efficacy of GD2-CAR T Cells in the Treatment of Neuroblastoma

for Neuroblastoma

Sponsor: The General Hospital of Western Theater Command

Sex: All·Age: 1 - 18

Code: NCT06684639·EARLY_Phase 1

Apply to this trial

DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations

for Solid Tumour

Sponsor: Cancer Research UK

Sex: All·Age: 18+

Code: NCT06988475·Phase 2, Phase 3

Apply to this trial

Phase I Study of Umbilical Cord Blood Natural Killer (NK) Cell Therapy for Children With High-risk, R/R Neuroblastoma.

for Neuroblastoma

Sponsor: Sun Yat-sen University

Sex: All·Age: 1 Day - 18

Code: NCT06631391·Phase 1

Apply to this trial

Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

for Neuroblastoma

21 sites incl. Birmingham

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: Up to 30

Code: NCT06541262·Phase 1, Phase 2

Apply to this trial

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

for B-cell Acute Lymphoblastic Leukemia

17 sites incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 6 Months - 25

Code: NCT06395103·Phase 1, Phase 2

Apply to this trial

Determining Patterns In Study Experiences of Neuroblastoma Patients

for Neuroblastoma

1 site in San Francisco

Sponsor: Power Life Sciences Inc.

Sex: All·Age: 18+

Code: NCT05918432

N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With Neuroblastoma

for High-risk Neuroblastoma

1 site in New York

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18 Months - 19

Code: NCT06528496·Phase 2

Apply to this trial

Agnostic Therapy in Rare Solid Tumors

for Urachal Cancer

Sponsor: Instituto do Cancer do Estado de São Paulo

Sex: All·Age: 18+

Code: NCT06638931·Phase 2

Apply to this trial

Autologous B7-H3 Chimeric Antigen Receptor T Cells in Relapsed/Refractory Solid Tumors

for Neuroblastoma

1 site in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 2 - 30

Code: NCT06500819·Phase 1

Apply to this trial

Hetrombopag in Promoting Platelet Engraftment After Auto-HSCT in Children With Neuroblastoma

for Delayed Platelet Engraftment

Sponsor: Beijing Children's Hospital

Sex: All·Age: Up to 18

Code: NCT06818916

Apply to this trial

Adding Of Naxitamb In Induction Therapy For High Risk Neuroblastoma

for Neuroblastoma

Sponsor: Guangzhou Women and Children's Medical Center

Sex: All·Age: 1 - 21

Code: NCT06574698

Apply to this trial

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

for Ganglioneuroblastoma, Nodular

154 sites incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 30

Code: NCT06172296·Phase 3

Apply to this trial

DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive Cancers

for Haematological Malignancy

Sponsor: Cancer Research UK

Sex: All·Age: All ages

Code: NCT05770037·Phase 2, Phase 3

Apply to this trial

Allogeneic Expanded Gamma Delta T Cells With GD2 Chemoimmunotherapy in Relapsed /Refractory Neuroblastoma or Refractory/ Relapsed Osteosarcoma

for Neuroblastoma

1 site in Atlanta

Sponsor: Emory University

Sex: All·Age: 12 Months+

Code: NCT05400603·Phase 1

Apply to this trial

SIOPEN BIOPORTAL, An International Registry Linked to a Virtual Biobank for Patients With Peripheral Neuroblastic Tumours

for Neuroblastoma

Sponsor: Institut Curie

Sex: All·Age: All ages

Code: NCT05192980

Apply to this trial

Naxitamab and Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) Combined With Isotretinoin for Maintenance Treatment of Patients With High-Risk Neuroblastoma in First Complete Response.

for Neuroblastoma

Sponsor: SciClone Pharmaceuticals

Sex: All·Age: 12 Months+

Code: NCT06047535·Phase 4

Abdominal Neuroblastoma Laparoscopic Surgery Risk Factors Stratification

for Neuroblastoma

Sponsor: Federal Research Institute of Pediatric Hematology, Oncology and Immunology

Sex: All·Age: 1 Day - 18

Code: NCT06296732

Apply to this trial

A Study of a Vaccine in Combination With Beta-glucan in People With Neuroblastoma

for Neuroblastoma

7 sites incl. Basking Ridge

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: All ages

Code: NCT06057948·Phase 2

Apply to this trial

MCT for the Harvard/UCSF ROBIN Center

for Glioma, Childhood Brainstem

2 sites incl. San Francisco

Sponsor: Brigham and Women's Hospital

Sex: All·Age: All ages

Code: NCT06000787

Apply to this trial

Induction Chemoimmunotherapy for Patients With High-risk Neuroblastoma

for Neuroblastoma

Sponsor: Federal Research Institute of Pediatric Hematology, Oncology and Immunology

Sex: All·Age: 18 Months - 18

Code: NCT06071897·Phase 3

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Clinical Analysis of Naxitamab (hu3F8) in the Treatment of Pediatric High Risk or Refractory/ Relapsed Neuroblastoma

for Neuroblastoma

Sponsor: Sun Yat-Sen University Cancer Center

Sex: All·Age: 12 Months+

Code: NCT06013618·Phase 2

Apply to this trial

Engineering Immune Organoids to Study Pediatric Cancer

for Brain Tumor

Sponsor: Gustave Roussy, Cancer Campus, Grand Paris

Sex: All·Age: Up to 25

Code: NCT05890781

Apply to this trial

APG-115 Alone or in Combination With APG-2575 in Children With Recurrent or Refractory Neuroblastoma or Solid Tumors

for Neuroblastoma

Sponsor: Ascentage Pharma Group Inc.

Sex: All·Age: 12 - 18

Code: NCT05701306·Phase 1

Apply to this trial

Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma

for Neuroblastoma

19 sites incl. Birmingham

Sponsor: Giselle Sholler

Sex: All·Age: 12 Months - 21

Code: NCT05489887·Phase 2

Apply to this trial

Allogeneic Hematopoietic Stem Cell Transplantation for 4/M Neuroblastoma

for Neuroblastoma

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Sex: All·Age: Up to 18

Code: NCT05303727·Phase 2

A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid Tumors

for Neuroblastoma

6 sites incl. Birmingham

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 18 Months - 40

Code: NCT05135975·Phase 2

Apply to this trial

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

for Pediatric Solid Tumor

1 site in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT04897321·Phase 1

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18F-mFBG LAFOV PET/CT Compared to 123I-mIBG Scintigraphy SPECT/CT for Evaluation of Children With Neuroblastoma

for Neuroblastoma

Sponsor: Rigshospitalet, Denmark

Sex: All·Age: Up to 18

Code: NCT05826158

Apply to this trial

Serial ctDNA and Molecular Residual Disease Monitoring in Neuroblastoma

for Neuroblastoma

Sponsor: Sun Yat-sen University

Sex: All·Age: All ages

Code: NCT07516678

Apply to this trial

68Ga-DOTATATE Neuroblastoma Imaging Pilot

for Neuroblastoma

Sponsor: Centre de recherche du Centre hospitalier universitaire de Sherbrooke

Sex: All·Age: Up to 21

Code: NCT04559217·Phase 2

Apply to this trial

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

for Colorectal Carcinoma

20 sites incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 30

Code: NCT04851119·Phase 1, Phase 2

Apply to this trial

Neuroblastoma clinical trials — common questions

Are neuroblastoma clinical trials free to join?

Yes. Participating in a neuroblastoma clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a neuroblastoma clinical trial?

Each neuroblastoma study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a neuroblastoma trial near me?

Use the location controls above. We'll show recruiting neuroblastoma trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many neuroblastoma trials are recruiting right now?

We're currently tracking roughly 44 recruiting neuroblastoma trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Neuroblastoma trials by city

Birmingham, AL Los Angeles, CA Boston, MA Gainesville, FL San Francisco, CA Cincinnati, OH Little Rock, AR Madison, WI Palo Alto, CA

Related specialties

Oncology Pediatric oncology