Pediatric oncology Clinical Trials

Recruiting pediatric oncology studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat pediatric oncology. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting pediatric oncology studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting pediatric oncology trials

Within

Proof-of-Concept Study of the SNOEZELEN Device on Anxiety Symptoms in Patients Hospitalized for Chemotherapy in a Pediatric Oncology Department

for Snoezelen

Sponsor: Centre Oscar Lambret

Sex: All·Age: 8 - 18

Code: NCT07202507

Apply to this trial

TeamTalk: Improving Inter-professional Communication During Cancer Treatment

for Pediatric Cancer

1 site in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT07083674

Food is Medicine in Survivorship: Examining the Feasibility and Impact of a Scalable Food Delivery and Culinary Medicine Program (FoodiiS) Among Pediatric Cancer Survivors and Their Families

for Pediatric Cancer

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT07218328

Study to Characterize Mismatched to Fully HLA-Matched Ossium HPC, Marrow and Living Donor Transplantation in Patients With Hematologic Malignancies

for Hematologic Malignancy

Sponsor: Ossium Health, Inc.

Sex: All·Age: 12 - 75

Code: NCT07710781

EWSR1 Immunotherapy in Ewing Sarcoma and DSRCT

for Ewing Sarcoma

1 site in Cleveland

Sponsor: Rabi Hanna

Sex: All·Age: 2+

Code: NCT07695311·Phase 1

HEM-iSMART E: Capivasertib + Venetoclax + Dexamethasone in Pediatric Patients With Relapsed or Refractory Hematological Malignancies

for Acute Lymphoblastic Leukemia

Sponsor: Princess Maxima Center for Pediatric Oncology

Sex: All·Age: 2 - 21

Code: NCT07175415·Phase 1, Phase 2

Pharmacogenomic Testing in Pediatric Hematology/Oncology Patients

for Pediatric Cancer

1 site in Charlotte

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: Up to 26

Code: NCT06744712

Phase 2 Study to Assess the Safety and Efficacy of Subcutaneous Blinatumomab in Patients With Measurable Residual Disease Positive B-cell Acute Lymphoblastic Leukemia

for Phase 2 Study

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07192237·Phase 2

CAR-T Treatment in Pediatric and Adult Acute Lymphoblastic Leukemia

for Acute Lymphoblastic Leukemia

Sponsor: Gruppo Italiano Malattie EMatologiche dell'Adulto

Sex: All·Age: All ages

Code: NCT07623655

Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma

for Pediatric Solid Tumors

1 site in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT07514819

my.naviGATE: A Guide to After-Treatment Effects for Adolescents and Young Adults

for Sarcoma

1 site in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 15 - 24

Code: NCT07516353

Atezolizumab in Combination With Stereotactic Body Radiation Therapy (SBRT) and Surgery for Relapsed Osteosarcoma

for Osteosarcoma

1 site in Atlanta

Sponsor: Emory University

Sex: All·Age: Up to 50

Code: NCT06492954·Phase 1

Apply to this trial

NANT 2021-02: Randomized MIBG With Vorinostat/Dinutuximab/Vorinostat + Dinutuximab

for Neuroblastoma

13 sites incl. Los Angeles

Sponsor: New Approaches to Neuroblastoma Therapy Consortium

Sex: All·Age: 1 - 30

Code: NCT07261241·Phase 2

Haploidentical Donor Cytokine-Induced Memory-Like Natural Killer Cells (CIML-NK) for Relapsed & Refractory Neuroblastoma

for Neuroblastoma

1 site in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 1 - 39

Code: NCT07635056·Phase 2

Apply to this trial

Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).

for Diffuse Intrinsic Pontine Glioma

6 sites incl. Los Angeles

Sponsor: BrainChild Bio, Inc

Sex: All·Age: 1 - 26

Code: NCT07680439·Phase 2

A Multicenter Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-Cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymph...

for B-All

8 sites incl. Los Angeles

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 1 - 25

Code: NCT05621291

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Anti-CRLF2-R/TSLPR Chimeric Antigen Receptor T Cells (TSLPR-CART) in Participants With Recurrent or Refractory CRLF2-R/TSLPR-Overexpressing B-Cell Acute Lymphoblastic Leukemia (B-ALL)

for B-All

1 site in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT07572136·Phase 1

Safety and Efficacy of Asciminib in Pediatrics and Young Adults With Relapse/Refractory (r/r) Philadelphia Positive (Ph+) or ABL-class Ph-like Acute Lymphoblastic Leukemia (ALL)

for Acute Lymphoblastic Leukemia

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 1 - 30

Code: NCT07387926·Phase 1, Phase 2

Apply to this trial

Combination Immunotherapy Targeting Sarcomas

for Sarcoma

Sponsor: Shenzhen Geno-Immune Medical Institute

Sex: All·Age: 1 - 75

Code: NCT04433221·Phase 1, Phase 2

Apply to this trial

Nurse-led Transitional Care to Improve Symptom Management in Childhood Cancer Survivors

for Pediatric Cancer

Sponsor: The Hong Kong Polytechnic University

Sex: All·Age: 13 - 18

Code: NCT07273682

Music Therapy for Oral Mucositis Pain in Pediatric Patients

for Oral Mucosa Discomfort

1 site in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 6 - 64·Accepts healthy volunteers

Code: NCT07653360

B7-H3.CD28Z.CART in Solid Tumors

for Pediatric Solid Tumor

1 site in Boston

Sponsor: Robbie Majzner

Sex: All·Age: 9 Months - 30

Code: NCT07358260·Phase 1

SHR2554/AZA + Overlapped TBF for High-risk/Relapsed Leukemia/MDS

for Acute Myeloid Leukemia

Sponsor: The First Affiliated Hospital of Soochow University

Sex: All·Age: 15 - 60

Code: NCT07562568·Phase 2

SHR2554/AZA + Overlapped Modified BUCY for High-risk/Relapsed Leukemia/MDS

for Acute Myeloid Leukemia

Sponsor: The First Affiliated Hospital of Soochow University

Sex: All·Age: 18 - 65

Code: NCT07575412·Phase 2

A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS)

for Rhabdomyosarcoma

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT07466316·Phase 3

CD22 CAR T-cells to Extend Remission Following Commercial CD19 CAR T-cells in Children, Adolescents, and Adults With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia

for Acute Lymphoblastic Leukemia

1 site in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 3 - 65

Code: NCT07328503·Phase 2

Apply to this trial

Strength Training Exercise in Pediatric Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (STEP-ALL)

for Leukemia

1 site in Chapel Hill

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All·Age: 6+·Accepts healthy volunteers

Code: NCT07634653

Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma

for Osteosarcoma

2 sites incl. Tampa

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 0 - 50

Code: NCT07321912·Phase 2

Apply to this trial

Whole Genome Sequencing (ChromoSeq®) for Acute Lymphoblastic Leukemia (ALL) Patients

for Acute Lymphoblastic Leukemia

1 site in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: Up to 30

Code: NCT07313592

Apply to this trial

Safety and Efficacy Evaluation of 4th Generation Safety-engineered CAR T Cells Targeting Sarcomas

for Sarcoma

Sponsor: Shenzhen Geno-Immune Medical Institute

Sex: All·Age: 1 - 75

Code: NCT03356782·Phase 1, Phase 2

Apply to this trial

4SCAR-T Therapy Targeting GD2, PSMA and CD276 for Treating Neuroblastoma

for Neuroblastoma

Sponsor: Shenzhen Geno-Immune Medical Institute

Sex: All·Age: 1 - 65

Code: NCT04637503·Phase 1, Phase 2

Apply to this trial

The Comparative Effectiveness Evaluation of the Impact of Digital Education

for Pediatric Cancer

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06979310

Early Discontinuation of Antibiotics in Paediatric High-risk Febrile Neutropenia

for Febrile Neutropenia (FN)

Sponsor: Hospital Universitari Vall d'Hebron Research Institute

Sex: All·Age: Up to 18

Code: NCT07590648·Phase 4

Phase I Study of FXS0683 in the Treatment of Blood Tumors

for B-Cell Lymphoma

Sponsor: Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.

Sex: All·Age: 18+

Code: NCT07616089·Phase 1

Neoadjuvant Radiotherapy and Surgery for High-Risk Localized Ewing Sarcoma

for Ewing Sarcoma

Sponsor: Peking University People's Hospital

Sex: All·Age: 12 Months+

Code: NCT07620431

ABL/JAK Inhibitors With Chemotherapy and Venetoclax for Ph-like ALL

for Ph-Like

Sponsor: Institute of Hematology & Blood Diseases Hospital, China

Sex: All·Age: 14 - 60

Code: NCT07454226

Apply to this trial

Phase I Study of Becotatug Vedotin for Safety and Efficacy in EGFR-Positive Pediatric Relapsed/Refractory or Metastatic Solid Tumors

for Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M)

Sponsor: Sun Yat-sen University

Sex: All·Age: 2 - 18

Code: NCT07584499·Phase 1

Apply to this trial

Using Text Messages to Improve Oral Chemotherapy for Adolescents and Adults With Acute Lymphoblastic Leukemia

for Acute Lymphoblastic Leukemia

1 site in Chicago

Sponsor: University of Chicago

Sex: All·Age: 15+

Code: NCT06446661

Apply to this trial

Telerehabilitation-Based Dance Therapy in Pediatric Cancer

for Pediatric Cancer

Sponsor: Akdeniz University

Sex: All·Age: 6 - 14

Code: NCT07596745

Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

for Atypical Teratoid/Rhabdoid Tumor

12 sites incl. Birmingham

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: Up to 26

Code: NCT06465199·Phase 1, Phase 2

Apply to this trial

A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant

for Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive

3 sites incl. Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07020533·Phase 1

Apply to this trial

Video Inspired Discussions About Ethical Outcomes in Pediatrics

for Pediatric Cancer

3 sites incl. Birmingham

Sponsor: Massachusetts General Hospital

Sex: All·Age: All ages

Code: NCT06786104

Apply to this trial

Phase I Clinical Trial of ThINKK Adoptive Immunotherapy After Allogeneic Hematopoietic Transplantation in Children With Leukemia or Neuroblastoma

for Leukaemia (Acute Lymphoblastic)

Sponsor: Michel Duval

Sex: All·Age: 2 - 12

Code: NCT07518654·Phase 1

Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors

for Adenocarcinoma

1 site in Orange

Sponsor: University of California, Irvine

Sex: All·Age: 18+

Code: NCT07628634·EARLY_Phase 1

Apply to this trial

Pain Caregiver Resource (PainCaRe)

for Pediatric Cancer

Sponsor: The Hospital for Sick Children

Sex: All·Age: All ages

Code: NCT06651190

ALL Backbone in AYAs

for Acute Lymphoblastic Leukemia

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18 - 51

Code: NCT07227584·Phase 2

Cord Blood Transplantation in Children and Young Adults With Blood Cancer

for Acute Myelogenous Leukemia

1 site in New York

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: Up to 26

Code: NCT07566377·Phase 2

Apply to this trial

Resistance Exercise and Incretin Mimetic for Cardiometabolic Health in Survivors of ALL With Obesity

for Acute Lymphoblastic Leukemia

1 site in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 18+

Code: NCT07228741·Phase 2

Apply to this trial

Tumor-Lymph Node Mapping

for Pediatric Solid Tumors

1 site in Rochester

Sponsor: University of Rochester

Sex: All·Age: 1 Month - 17

Code: NCT07054944

Apply to this trial

Evaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS)

for Ewing Sarcoma

5 sites incl. Los Angeles

Sponsor: Amgen

Sex: All·Age: 2+

Code: NCT07297979·Phase 1

Apply to this trial

Cytokine Armored GPC3 Specific Chimeric Antigen Receptor Expressing T-cells in Adults With Solid Tumors

for Solid Tumor (Excluding CNS)

1 site in Seattle

Sponsor: Seattle Children's Hospital

Sex: All·Age: 21+

Code: NCT07224568·Phase 1

Questionnaire on Congenital Cancer Signs Through Self-Assessment

for Cancer Predisposition Syndromes

Sponsor: Insel Gruppe AG, University Hospital Bern

Sex: All·Age: Up to 21

Code: NCT07378423

Apply to this trial

Social and Physical Activity as Rehabilitation for Preschool Kids With Cancer

for Pediatric Cancer

Sponsor: Rigshospitalet, Denmark

Sex: All·Age: 12 Months - 71 Months

Code: NCT07213024

Wearable Technology-Supported Exercise Program for Fatigue and Quality of Life in Pediatric Cancer Patients (WE-EX PedsCa)

for Pediatric Cancer

Sponsor: Istanbul University

Sex: All·Age: 13 - 18

Code: NCT07337681

From Kitchen to Clinic

for Pediatric Cancer

1 site in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 5 - 21

Code: NCT07454902

HEM-SURVIVE: Structuralized Follow-up for Childhood Hematological Malignancy Survivors

for Acute Lymphoblastic Leukemia

Sponsor: The Children's Hospital of Zhejiang University School of Medicine

Sex: All·Age: 1 - 21

Code: NCT07483749

Efficacy of Laser Interstitial Thermal Therapy in Young Persons With Low-grade Glioma

for Low-grade Glioma

1 site in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 2 - 25

Code: NCT07506239

Apply to this trial

A Study of Gefitinib, Trametinib, Disulfiram, and Sunitinib in Addition to Standard Chemotherapy in People With Osteosarcoma

for Osteosarcoma

7 sites incl. Basking Ridge

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 6 - 49

Code: NCT07477457·Phase 2

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Treatment for Ph-negative ALL for Adults up to 65 Years

for Acute Lymphoblastic Leukemia

Sponsor: PETHEMA Foundation

Sex: All·Age: 18 - 65

Code: NCT07443592

Apatinib Combined With Liposomal Irinotecan for Refractory or Metastatic Osteosarcoma

for Osteosarcoma

Sponsor: Peking University People's Hospital

Sex: All·Age: 12 - 65

Code: NCT07479732·Phase 1, Phase 2

Apply to this trial

Pediatric oncology clinical trials — common questions

Are pediatric oncology clinical trials free to join?

Yes. Participating in a pediatric oncology clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a pediatric oncology clinical trial?

Each pediatric oncology study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a pediatric oncology trial near me?

Use the location controls above. We'll show recruiting pediatric oncology trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many pediatric oncology trials are recruiting right now?

We're currently tracking roughly 218 recruiting pediatric oncology trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Pediatric oncology trials by city

Los Angeles, CA Birmingham, AL Duarte, CA Chicago, IL San Francisco, CA Seattle, WA Boston, MA Palo Alto, CA Tampa, FL Aurora, CO Gainesville, FL Cleveland, OH

Conditions in this area

Pediatric cancer Osteosarcoma Ewing sarcoma Rhabdomyosarcoma Neuroblastoma Acute lymphoblastic leukemia