Heart disease Clinical Trials in Baltimore, MD
As of September 2026, 42 paid clinical trials are recruiting for Heart disease in Baltimore, Maryland. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Baltimore
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
43 clinical trials for Heart disease
·Clear filters·A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
SELUTION 4 De Novo Small Vessel IDE Trial
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
Transition to KPL-387 Monotherapy Dosing & Administration Study
Virtue® SAB in the Treatment of Coronary ISR Trial
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation
The Fourth Left Atrial Appendage Occlusion Study
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
Implementation of a Beauty Salon-Based Strategy for Blood Pressure Management Among Women
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
Integrating Free-choice Marketplace, dieTitian coacHing, cultuRally Tailored messagIng to improVE Blood Pressure
CTSN Embolic Protection Trial
PET/CT* vs. Cardiac CT for Detecting Coronary Atherosclerotic Disease [*PET: Positron Emission Tomography; CT: Computed Tomography]
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women
Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction
The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)
Mobile Health Technology-Enabled AFib Management
320-detector Computed Tomography to Assess Myocardial Extracellular Volume Fraction in Patients With Atrial Fibrillation Before AF Ablation.
Groceries Plus Multi-Component Lifestyle Intervention for Adults With Hypertension and Type 2 Diabetes
Imaging the Pathogenesis of Cerebral Small Vessel Disease
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry
Hemodynamic Assessment of underLying myocyTe Function in Right Heart Failure
Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease
A Cardiometabolic Health Program Linked With Clinical-Community Support and Mobile Health Telemonitoring to Reduce Health Disparities
Understanding and Addressing Risks of Low Socioeconomic Status and Diabetes for Heart Failure
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
Top Research Study Locations in Baltimore
Researchers run research studies in Baltimore, MD at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Johns Hopkins University | Cystic Fibrosis, Pancreatic Ductal Adenocarcinoma (PDAC), Prostate Cancer | 190 |
| Johns Hopkins Hospital | Barrett Esophagus, Bladder Cancer, Urothelial Cancer | 125 |
| Johns Hopkins University/Sidney Kimmel Cancer Center | Acute Myeloid Leukemia, Acute Myeloid Leukemia Post Cytotoxic Therapy, B Acute Lymphoblastic Leukemia | 63 |
| University of Maryland | Acute Kidney Injury, Carcinoma, Non-Small-Cell Lung, Non Small Cell Lung Cancer | 57 |
| Sinai Hospital of Baltimore | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, B Acute Lymphoblastic Leukemia | 48 |
| University of Maryland Medical Center | Subarachnoid Hemorrhage, Acute Kidney Injury, Cardiomyopathies | 46 |
| University of Maryland/Greenebaum Cancer Center | Anatomic Stage II Breast Cancer AJCC v8, Acute Myeloid Leukemia, Anatomic Stage IIIA Breast Cancer AJCC v8 | 42 |
| Johns Hopkins University School of Medicine | Alcohol Use Disorder, Amputation, Traumatic, Chronic Low-back Pain | 40 |
| Johns Hopkins | Primary Immune Deficiency Disorder, Chronic Obstructive Pulmonary Disease (COPD), Pancreatic Cancer | 37 |
| Kennedy Krieger Institute | Adrenomyeloneuropathy, Autism Spectrum Disorder, Cerebral Palsy | 30 |
| Johns Hopkins School of Medicine | Alzheimer Disease, Bilateral Vestibular Hypofunction, Bilateral Vestibulopathy | 29 |
| Johns Hopkins Bayview Medical Center | Carcinoma, Non-Small-Cell Lung, Healthy, Stroke | 25 |
| University of Maryland, Baltimore | Fatigue, Stroke, ADPKD (Autosomal Dominant Polycystic Kidney Disease) | 23 |
| Johns Hopkins Medicine | Functional Recovery, Achondroplasia, Acute Kidney Injury | 21 |
| The Johns Hopkins Hospital | ALS (Amyotrophic Lateral Sclerosis), Achilles Tendon Repairs/Reconstructions, Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar) | 21 |
| Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD | Cognitive Impairment, Falls, Obesity | 20 |
| Greater Baltimore Medical Center | Anatomic Stage II Breast Cancer AJCC v8, Amblyopia, Anatomic Stage IIIA Breast Cancer AJCC v8 | 20 |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Breast Cancer, Kaposi Sarcoma, Lymphoma | 19 |
| John Hopkins University | Amyotrophic Lateral Sclerosis, Advanced Solid Tumors, Allogenic Transplant Patients | 19 |
| University of Maryland School of Medicine | Acute-On-Chronic Liver Failure, Brain Injury, Caregiver Distress | 17 |
| Johns Hopkins Sidney Kimmel Comprehensive Cancer Center | Prostate Cancer, Kidney Cancer, Metastatic Castration-resistant Prostate Cancer | 16 |
| Mercy Medical Center | Breast Cancer, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | 16 |
| National Institute on Drug Abuse | Normal Physiology, Alcohol Use Disorder, Substance Use Disorder | 14 |
| Maryland Proton Treatment Center | Breast Cancer, Biliary Tract Cancer, Brain Tumor | 13 |
| National Institute of Aging, Clinical Research Unit | Healthy Volunteers, Aging, Alzheimer's Disease | 13 |
Active & Upcoming Studies in Baltimore (2026)
Recruiting trials in Baltimore grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (418 active studies)
- A Study of Topical Duvelisib in Participants With Early-stage Mycosis Fungoides · Phase 1 · SecuraBio
- Phase 2 Study of Daraxonrasib in Recurrent KRAS-Mutant Biliary Tract Cancer · Phase 2 · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Neurology & pain (117 active studies)
- DockTales for Chronic Pain · University of Maryland, Baltimore
- Study to Examine the Effect of Silicone Mouth Tape on Snoring and Mild Sleep Apnea. · Phase 2 · Johns Hopkins University
Cardiovascular (72 active studies)
- Testing Heart Failure Resilience Intervention for Caregivers (HEROIC) in Advanced Heart Failure · Phase 2 · Johns Hopkins University
- Multi-Scale Analysis of Phenotypes in Heart Failure (MAP-HEART) · National Heart, Lung, and Blood Institute (NHLBI)
Diabetes & metabolic (56 active studies)
- Multimodal Glucose Prediction in Type 2 Diabetes · Johns Hopkins University
- Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS) · Phase 3 · Eli Lilly and Company
HIV / STI (43 active studies)
- Decision Support Tool to Integrate PrEP Into Emergency Departments · Phase 1 · George Washington University
- ED Patient's Perceptions and Acceptability Toward a Novel POC HCV Viral Load Testing · Johns Hopkins University
Mental health & behavior (42 active studies)
- Duloxetine and aeRobic Exercise to Improve Function in VEterans With Knee Osteoarthritis (DRIVE) · Phase 2 · VA Office of Research and Development
- Cannabidiol as an Adjunct Treatment for Alcohol Withdrawal and Craving · Phase 2, Phase 3 · Johns Hopkins University
Eye & vision (24 active studies)
- Measuring the Effects of Netarsudil, Latanoprost, and Combination Therapy on Episcleral and Retinal Blood Flow in Ocular Hypertension and Glaucoma Suspects · Phase 4 · University of Maryland, Baltimore
- Optic Nerve Head Strain in Non-glaucoma Subjects · EARLY_Phase 1 · Johns Hopkins University
Pediatric (20 active studies)
- Hypoxic Red Blood Cells in Sickle Cell Anemia · Hemanext
- Mobile Technology to Reduce Teen Substance Misuse · Evidence-Based Practice Institute, Seattle, WA
Vaccines (17 active studies)
- A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age · Phase 3 · GlaxoSmithKline
- Safety and Immunogenicity of Chimeric Hemagglutinin mRNA Vaccine Candidates · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
Common conditions studied in Baltimore
- Breast Cancer (23 active studies)
- Prostate Cancer (20 active studies)
- Stroke (17 active studies)
- Heart Failure (15 active studies)
- Opioid Use Disorder (14 active studies)
- Pancreatic Cancer (14 active studies)
Leading research sponsors in Baltimore
- Johns Hopkins University
- University of Maryland, Baltimore
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
- National Cancer Institute (NCI)
- AstraZeneca
Frequently asked questions
How many paid clinical trials are currently recruiting in Baltimore?
There are approximately 1,549 recruiting clinical trials in Baltimore, Maryland listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Baltimore pay participants?
Most recruiting trials in Baltimore compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Baltimore?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Baltimore?
The most common conditions under active study in Baltimore include Breast Cancer (23), Prostate Cancer (20), Stroke (17), Heart Failure (15), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Baltimore?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Baltimore on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Baltimore?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Baltimore?
Recruiting research sites in Baltimore include Johns Hopkins University, Johns Hopkins Hospital, Johns Hopkins University/Sidney Kimmel Cancer Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Baltimore right now?
The largest active categories in Baltimore are Cancer & tumors (418), Neurology & pain (117), Cardiovascular (72). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.