Oncology Clinical Trials in Buffalo, NY
As of July 2026, 109 paid clinical trials are recruiting for Oncology in Buffalo, New York. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Buffalo
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
The Canopy Cancer Collective Clinical Registry Protocol
111 clinical trials for Oncology
·Clear filters·↓ Download CSVA Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy
Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel
A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer
A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)
A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies
Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma
Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma
Pan Tumor Rollover Study
Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia
A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)
A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors
Adjuvant Temozolomide ± 5-Aminolevulinic Acid + Low Intensity Diffuse Ultrasound Sonodynamic Therapy System for Newly Diagnosed Glioblastoma
A Study of ASP3082 in Adults With Advanced Solid Tumors
A Phase 1 Study of BMS-986500 as Monotherapy or Combination Therapy in Advanced Solid Tumors
A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors
A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of Arlocabtagene Autoleucel (BMS-986393) in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma
A Study of the Efficacy and Safety of Lisocabtagene Maraleucel (Liso-cel) as First-Line Therapy in Adults With Transplant-Ineligible Primary Central Nervous System Lymphoma
Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors
A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With REGN5678 for Adult Participants With Advanced Prostate Cancer
A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)
Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer
A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapy
Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC
Study of SGR-1505 in Mature B-Cell Neoplasms
A Phase 1 Study of LNCB74 in Advanced Solid Tumors
A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Endometrial Cancer.
A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome
A Study to Evaluate the Safety and Efficacy of Gocatamig (MK-6070) and Ifinatamab Deruxtecan (I-DXd) in Participants With Relapsed/Refractory Extensive-Stage Small Cell Lung Cancer (MK-6070-002)
A Study of JNJ-86974680 in Participants With Advanced Non-small Cell Lung Cancer
A Phase 1 of CTX-8371 in Patients With Advanced Malignancies
A Study to Assess the Safety, Tolerability, and Antileukemic Activity of Debio 1562M in Participants With Acute Myeloid Leukemia (AML)
About research studies in Buffalo
Buffalo has approximately 413 recruiting research studies across a wide range of therapeutic areas. New York is home to leading academic medical centers such as Memorial Sloan Kettering, Weill Cornell Medicine, Mount Sinai, NYU Langone, and Columbia University Irving Medical Center. These institutions anchor a research ecosystem that covers oncology, cardiology, neurology, and rare disease.
Top Research Study Locations in Buffalo
Researchers run research studies in Buffalo, NY at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Roswell Park Cancer Institute | Acute Myeloid Leukemia, Malignant Solid Neoplasm, Recurrent Fallopian Tube Carcinoma | 158 |
| Roswell Park Comprehensive Cancer Center | Acute Myeloid Leukemia, Leukemia, Myeloid, Acute, Non-Hodgkin Lymphoma | 46 |
| University at Buffalo | Cardiovascular Diseases, Acute Abstinence From Cigarettes vs E-cigarettes (ENDS), Acute Respiratory Failure | 18 |
| State University of New York at Buffalo | Acute Ischemic Stroke, Acute Myeloid Leukemia (AML), Birth-weight-for-gestational-age z Score | 9 |
| Buffalo General Medical Center | Acute Ischemic Stroke, Aortic Insufficiency, Aortic Regurgitation | 8 |
| Roswell Park | Glioma, MAPK Pathway Gene Mutation, MEK Mutation | 5 |
| Erie County Medical Center | Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands, Anastomosis, Surgical, Free Tissue Transfer | 4 |
| University at Buffalo Neurosurgery | Cerebral Aneurysms, Clinical Need for Cranioplasty, Clinical Need for Craniotomy or Craniectomy | 4 |
| University of Buffalo | Aortic Valve Insufficiency, Aortic Valve Stenosis, Interstitial Lung Disease (ILD) | 4 |
| VA Western New York Healthcare System, Buffalo, NY | Alcohol-Related Disorders, Brain Concussion, Comorbid Post-Traumatic Stress Disorder and OCD | 4 |
| Jacobs Institute | Aneurysm, Leak, Cerebrospinal Fluid, Moyamoya Disease | 3 |
| Oishei Children's Hospital | Bronchiolitis Acute, Children, Only, Failed or Difficult Intubation, Sequela | 3 |
| UBMD Pediatrics | Idiopathic Short Stature, Diabetes Mellitus, Type 2 | 3 |
| University at Buffalo / Great Lakes Cancer Care | Integrative Oncology, Medical Nutrition Therapy, Medical Oncology | 2 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, MASH With Fibrosis, NASH - Nonalcoholic Steatohepatitis | 2 |
| Buffalo General | Diastolic Heart Failure, Heart Failure, Heart Failure With Mid Range Ejection Fraction | 2 |
| Circuit Clinical | Hematologic Malignancies, Solid Tumors, Type 1 Diabetes | 2 |
| Dent Neurological Institute | Alzheimer Disease, Dementia, Generalized Myasthenia Gravis | 2 |
| Division of Behavioral Medicine Department of Pediatrics Jacobs School of Medicine and Biomedical Sciences State University of New York at Buffalo | Breastfeeding, Childhood Obesity, Pregnancy | 2 |
| Research Foundation SUNY Buffalo | Aortoiliac Occlusive Disease, PFO - Patent Foramen Ovale, Stroke | 2 |
| Rochester Clinical Research - Buffalo | Obesity, Osteoarthritis, Overweight | 2 |
| Ross Eye Institute, University of Buffalo, Med School Dept Ophthalmology | Amblyopia | 2 |
| Sisters of Charity Hospital | Death; Neonatal, Intubation Complication, Percutaneous Coronary Intervention | 2 |
| The Cystic Fibrosis Center of Western New York | Cystic Fibrosis | 2 |
| UBMD Neurology | Huntington Disease, Parkinsons Disease (PD) | 2 |
Active & Upcoming Studies in Buffalo (2026)
Recruiting trials in Buffalo grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (194 active studies)
- Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial · Phase 3 · National Cancer Institute (NCI)
- CIMAvax-EGF With KRAS G12C Inhibitor for the Treatment of Advanced, KRAS G12C Mutated Non Small Cell Lung Cancer · Phase 2 · Roswell Park Cancer Institute
Neurology & pain (25 active studies)
- OsseoFit Stemless Shoulder System (Anatomic) · Zimmer Biomet
- REal-world Clinical evAulation of Medtronic NeurOVascular Products for Acute Ischemic Stroke (RECANOVA Registry) · Medtronic Neurovascular Clinical Affairs
Diabetes & metabolic (21 active studies)
- A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes · Phase 3 · Novo Nordisk A/S
- A Study of Weekly Oral Dose of Ecnoglutide (VRB-101) for Weight Maintenance in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities · Phase 2 · Verdiva Bio Dev Limited
Cardiovascular (21 active studies)
Mental health & behavior (13 active studies)
- Relapse Prevention Trial Evaluating KarXT Treatment in Schizophrenia · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
- Understanding Tobacco and Cannabis Co-Use Practices: Initiation, Escalation, and Maintenance · Roswell Park Cancer Institute
Pediatric (12 active studies)
- Developmental Trajectories of Reinforcer Pathology and Childhood Obesity · State University of New York at Buffalo
- Pain Control Alternatives in Pediatric Patients With Distal Radius Fractures · Phase 3 · State University of New York at Buffalo
Eye & vision (3 active studies)
- Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial · University of Pennsylvania
- Comparison of Intraocular Pressure Measurement With the Novel TonoVera Device With Other Commonly Used Devices · State University of New York at Buffalo
Vaccines (2 active studies)
- EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease · Phase 3 · Pfizer
- SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry · Massive Bio, Inc.
HIV / STI (2 active studies)
- Examining Migration, Social Bonds, Transnationalism, and HIV Prevention Pathways Among African Immigrants. · State University of New York at Buffalo
- Blood Collection Biorepository for Liver Disease Research · State University of New York at Buffalo
Common conditions studied in Buffalo
- Acute Myeloid Leukemia (13 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Breast Cancer (7 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Malignant Solid Neoplasm (7 active studies). Recruiting Malignant Solid Neoplasm studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Endometrial Cancer (6 active studies). Recruiting Endometrial Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Anatomic Stage IV Breast Cancer AJCC v8 (5 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Cancer (5 active studies). Recruiting Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Buffalo
- Roswell Park Cancer Institute
- State University of New York at Buffalo
- National Cancer Institute (NCI)
- Children's Oncology Group
- Alliance for Clinical Trials in Oncology
Local regulations and guidelines
Clinical trials in New York are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Trials conducted in New York must also comply with the NY SHIELD Act's data-protection requirements and additional oversight from the New York State Department of Health.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Buffalo. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Buffalo
Hipa.ai aggregates every recruiting study in Buffalo from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Buffalo?
There are approximately 413 recruiting clinical trials in Buffalo, New York listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Buffalo pay participants?
Most recruiting trials in Buffalo compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Buffalo?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Buffalo?
The most common conditions under active study in Buffalo include Acute Myeloid Leukemia (13), Breast Cancer (7), Malignant Solid Neoplasm (7), Endometrial Cancer (6), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Buffalo?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Buffalo on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Buffalo?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Buffalo?
Recruiting research sites in Buffalo include Roswell Park Cancer Institute, Roswell Park Comprehensive Cancer Center, University at Buffalo, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Buffalo right now?
The largest active categories in Buffalo are Cancer & tumors (194), Neurology & pain (25), Diabetes & metabolic (21). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.