As of June 2026, 720 paid clinical trials are recruiting in Charleston, South Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Charleston offers studies at sites including Medical University of South Carolina for conditions such as Stroke, Depression, Heart Failure, Breast Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Charleston has approximately 720 recruiting research studies across a wide range of therapeutic areas. South Carolina hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.
Researchers run research studies in Charleston, SC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Medical University of South Carolina | Stroke, Breast Cancer, Cancer | 396 |
| Medical University of South Carolina (MUSC) | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 30 |
| Ralph H. Johnson VA Medical Center, Charleston, SC | Stroke, Depression, PTSD | 23 |
| Ralph H Johnson VA Medical Center | Stage IV Lung Cancer AJCC v8, Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum | 11 |
| MUSC | Focal Epilepsy, Tricuspid Valve Disease, Arrhythmias | 8 |
| Ralph H. Johnson VA Health Care System | Alzheimer Disease, Adjustment Disorders, Agitation | 8 |
| Hollings Cancer Center | Acute Myeloid Leukemia, B-Cell Non-Hodgkin Lymphoma, Breast Cancer | 7 |
| Medical University of South Carolina Hollings Cancer Center | Brain Metastases, Cancer (With CNS Involvement), Locally Advanced Pancreatic Adenocarcinoma | 5 |
| GSK Investigational Site | Asthma, Chickenpox, Hypereosinophilic Syndrome | 4 |
| Bon Secours Saint Francis Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, HER2-Negative Breast Carcinoma | 4 |
| Hollings Cancer Center at Medical University of South Carolina | B-cell Non Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, Locally Advanced Pancreatic Adenocarcinoma | 4 |
| Lowcountry Lung and Critical Care | Idiopathic Pulmonary Fibrosis, Progressive Pulmonary Fibrosis, Hypersensitivity Pneumonitis | 4 |
| MUSC Hollings Cancer Center | Advanced Renal Cell Carcinoma (RCC), Advanced Solid Tumor, Cachexia | 4 |
| Medical University of South Carolina Children's Hospital | Focal Segmental Glomerulosclerosis, Adrenal Insufficiency, Arrythmia | 4 |
| Medical University of South Carolina University Hospital | Intracerebral Hemorrhage, Ischemic Stroke, Atrial Fibrillation | 4 |
| Roper Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, HER2-Negative Breast Carcinoma | 4 |
| Medical University South Carolina | Knee Arthroplasty, Total, Lower Respiratory Tract Infection, Myasthenia Gravis | 3 |
| Ralph H. Johnson VA Medical Center | Alzheimers Disease, Prostate Cancer, Pulmonary Disease, Chronic Obstructive | 3 |
| Trident Medical Center | Persistent Atrial Fibrillation, Atrial Fibrillation (AF), Paroxysmal AF | 3 |
| 30 Bee Street | Depression, Post Stroke Pain | 2 |
| 89bio Clinical Study Site | Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis | 2 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, MASH With Fibrosis, NASH - Nonalcoholic Steatohepatitis | 2 |
| Charleston Neuroscience Institute, LLC (Charleston) | Macular Edema Secondary to Inflammation | 2 |
| Charleston Oncology - Roper | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, HER2-Negative Breast Carcinoma | 2 |
| Charleston Oncology - Saint Francis | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, HER2-Negative Breast Carcinoma | 2 |
Recruiting trials in Charleston grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Clinical trials in South Carolina are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. South Carolina research additionally follows state public health department oversight and any applicable state privacy statutes.
Hipa.ai aggregates every recruiting study in Charleston from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
There are approximately 720 recruiting clinical trials in Charleston, South Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Charleston compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Charleston include Stroke (18), Cancer (11), Depression (11), Heart Failure (11), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Charleston on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Charleston include Medical University of South Carolina, Medical University of South Carolina (MUSC), Ralph H. Johnson VA Medical Center, Charleston, SC, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Charleston are Cancer & tumors (194), Neurology & pain (67), Mental health & behavior (59). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.