Paid Clinical Trials in Dayton, OH
As of June 2026, 189 paid clinical trials are recruiting in Dayton, Ohio. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Dayton offers studies at sites including Miami Valley Hospital North for conditions such as Stage IV Lung Cancer AJCC v8, Malignant Solid Neoplasm, Stage IIIB Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Dayton
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Dayton has approximately 189 recruiting research studies across a wide range of therapeutic areas. Ohio is home to The Ohio State University Wexner Medical Center, Cleveland Clinic, Cincinnati Children's, and University Hospitals Cleveland Medical Center — collectively running clinical trials across every major therapeutic area.
Top Research Study Locations in Dayton
Researchers run research studies in Dayton, OH at 50 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Miami Valley Hospital North | Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Recurrent Lung Non-Small Cell Carcinoma | 59 |
| Miami Valley Hospital | Stage IV Lung Cancer AJCC v8, Recurrent Lung Non-Small Cell Carcinoma, Stage IIIB Lung Cancer AJCC v8 | 56 |
| Dayton Physician LLC - Englewood | Malignant Solid Neoplasm, Stage IIIB Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8 | 40 |
| Premier Blood and Cancer Center | Stage IV Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Extensive Stage Lung Small Cell Carcinoma | 37 |
| Dayton Children's Hospital | B Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Cystic Fibrosis | 34 |
| Good Samaritan Hospital - Dayton | Advanced Lung Non-Small Cell Carcinoma, Anatomic Stage IV Breast Cancer AJCC v8, Bladder Adenocarcinoma | 7 |
| Dayton Physician LLC-Miami Valley Hospital North | Metastatic Malignant Neoplasm in the Brain, Acral Lentiginous Melanoma, Anatomic Stage IV Breast Cancer AJCC v8 | 5 |
| PriMED Clinical Research | Diabetes Mellitus, Type 2, Obesity, Overweight | 4 |
| Clinical Trial Site | Advanced Breast Cancer, Breast Cancer, ER Positive Breast Cancer | 3 |
| Orthopedic Associates of Southwest Ohio | Arthritis, Carpal Tunnel Syndrome, Decreased Motion at the Proximal Radioulnar Joint and/or the Radio-humeral Joint | 3 |
| GSK Investigational Site | Chickenpox, Asthma | 3 |
| Hometown Urgent Care and Research - Dayton | Gout, Obesity or Overweight, Tophaceous Gout | 3 |
| META Medical Research Institute | Diabetic Peripheral Neuropathic Pain, Chronic Low-back Pain, Diabetic Neuropathic Pain | 3 |
| Premier Health | Focal Epilepsy, Burnout, Professional, Implicit Bias | 3 |
| 89bio Clinical Study Site | Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis | 2 |
| Dayton Gastroenterology, LLC | Ulcerative Colitis | 2 |
| Dayton Physician Network | Chronic Lymphocytic Leukemia, CLL, Small Lymphocytic Lymphoma | 2 |
| Dayton VA Medical Center | Actinic Keratoses, Aging, Cardiovascular Diseases | 2 |
| Dayton VA Medical Center, Dayton, OH | Actinic Keratosis, Imipramine, Opioid Use Disorder | 2 |
| Dayton Veterans Affairs Medical Center | Malignant Digestive System Neoplasm, Malignant Female Reproductive System Neoplasm, Malignant Genitourinary System Neoplasm | 2 |
| Local Institution - 1122 | Psychosis Associated With Alzheimer's Disease | 2 |
| Wright State University | Burnout, Professional, Implicit Bias, Motivational Interviewing | 2 |
| DSI Research, LLC | Ulcerative Colitis, Crohn's Disease | 2 |
| Galderma Investigational | Prurigo Nodularis, Atopic Dermatitis | 2 |
| Akero Clinical Study Site | MASH With Fibrosis, NASH With Fibrosis | 1 |
| Anthos Investigative | Atrial Fibrillation (AF) | 1 |
| CEI Physicians PSC, LLC dba | Geographic Atrophy, Macular Degeneration | 1 |
| Childrens Medical Center | Crohn's Disease | 1 |
| DSI Research Northridge LLC | Crohn's Disease, Ulcerative Colitis | 1 |
| Dayton Children's Hemostasis and Thrombosis Center | Bleeding Disorder, Connective Tissue Disorder, Factor IX Deficiency | 1 |
| Dayton Children's Hospital - Hope Center | Suicidal Ideation, Suicide Prevention, Suicide, Attempted | 1 |
| Dayton Children's Hospital - Main | Suicidal Ideation, Suicide Prevention, Suicide, Attempted | 1 |
| Dayton Clinical Research | Chronic Obstructive Pulmonary Disease | 1 |
| Dayton VA Medical Center - NAVREF - PPDS | Hepatocellular Carcinoma | 1 |
| Digestive Specialists | Metabolic Dysfunction-associated Steatohepatitis | 1 |
| Investigative | Hidradenitis Suppurativa (HS) | 1 |
| Kettering Health Dayton | Lumbar Spinal Stenosis | 1 |
| Kettering Health Research Institute | Cardiovascular Diseases, Functional Mitral Regurgitation, Heart Diseases | 1 |
| Local Institution - 1258 | Alzheimer Disease | 1 |
| Meta Medical Research Institute, LLC | Degenerative Disc Disease | 1 |
| Miami Valley Ambulatory Surgery Center | Lumbar Spinal Stenosis | 1 |
| NDx Clinical Research | Alzheimer Disease, Alzheimer Disease Due to P. Gingivalis | 1 |
| NDx Clinical Research Inc. | Alzheimer's Disease | 1 |
| NDx Clinical Research, Inc | Relapsing-remitting Multiple Sclerosis (RRMS) | 1 |
| NDx Clinical Research, Inc. | Alzheimer Disease, Dementia, Plaque, Amyloid | 1 |
| Naval Medical Research Unit | Motion Sickness, Space Motion Sickness, Vestibular Disorder | 1 |
| Neumora Investigator Site | Major Depressive Disorder | 1 |
| Neurology Diagnostics, Inc. | Chronic Migraine, Episodic Migraine | 1 |
| Ohio Pediatric Research Association | Influenza | 1 |
| Premier Cardiovascular Institute | Peripheral Vascular Diseases | 1 |
Active & Upcoming Studies in Dayton (2026)
Recruiting trials in Dayton grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (84 active studies)
- Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations · Phase 3 · SWOG Cancer Research Network
- AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01) · Phase 3 · AstraZeneca
Neurology & pain (14 active studies)
- A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT). · Phase 3 · Eli Lilly and Company
- A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Diabetic Peripheral Neuropathic Pain · Phase 2 · Eli Lilly and Company
Diabetes & metabolic (10 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes · Phase 2 · Novo Nordisk A/S
Cardiovascular (8 active studies)
- A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity · Phase 3 · Novo Nordisk A/S
- Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease · Phase 3 · Alnylam Pharmaceuticals
Pediatric (3 active studies)
Vaccines (2 active studies)
- A Study to Evaluate the Safety and Efficacy of CD388 for Prevention of Influenza · Phase 3 · Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
- A Surveillance Study of Susceptibility to Baloxavir Marboxil in Pediatric Participants With Influenza and Transmission of Influenza to Household Contacts · Phase 3 · Hoffmann-La Roche
Mental health & behavior (1 active study)
- A Frequency-Modulated Music Intervention to Enhance Cognitive Processing Therapy (CPT) for PTSD · Ohio State University
Eye & vision (1 active study)
- A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy · Astellas Pharma Global Development, Inc.
Common conditions studied in Dayton
- Stage IV Lung Cancer AJCC v8 (6 active studies). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.
- Malignant Solid Neoplasm (5 active studies). Recruiting Malignant Solid Neoplasm studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Stage IIIB Lung Cancer AJCC v8 (5 active studies). Lung cancer research focuses on targeted therapies for specific mutations such as EGFR, ALK, and KRAS, alongside immunotherapy regimens.
- Anatomic Stage II Breast Cancer AJCC v8 (4 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Chronic Lymphocytic Leukemia (4 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Crohn's Disease (4 active studies). Recruiting Crohn's Disease studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Dayton
- National Cancer Institute (NCI)
- SWOG Cancer Research Network
- Children's Oncology Group
- NRG Oncology
- Alliance for Clinical Trials in Oncology
Local regulations and guidelines
Clinical trials in Ohio are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Ohio research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Dayton. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Dayton
Hipa.ai aggregates every recruiting study in Dayton from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Dayton?
There are approximately 189 recruiting clinical trials in Dayton, Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Dayton pay participants?
Most recruiting trials in Dayton compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Dayton?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Dayton?
The most common conditions under active study in Dayton include Stage IV Lung Cancer AJCC v8 (6), Malignant Solid Neoplasm (5), Stage IIIB Lung Cancer AJCC v8 (5), Anatomic Stage II Breast Cancer AJCC v8 (4), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Dayton?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Dayton on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Dayton?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Dayton?
Recruiting research sites in Dayton include Miami Valley Hospital North, Miami Valley Hospital, Dayton Physician LLC - Englewood, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Dayton right now?
The largest active categories in Dayton are Cancer & tumors (84), Neurology & pain (14), Diabetes & metabolic (10). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.