Emergency Department-Initiated Team-Based Care for Severe Hypertension
for Severe Hypertension
Sites in Detroit, Dearborn & Wyandotte
Sponsor: Henry Ford Health System
Sex: All·Age: 18 - 85
Code: NCT07777237·Not Yet Recruiting·Listed Aug 20, 2026
Cardiology Clinical Trials in Detroit, MI
As of August 2026, 38 paid clinical trials are recruiting for Cardiology in Detroit, Michigan. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Detroit
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
39 clinical trials for Cardiology
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OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
for Cardiovascular Disease
Drug: Olpasiran
Sites in Detroit, Southfield +192 more locations
Sponsor: Amgen
Sex: All·Age: 50 - 105
Code: NCT07136012·Phase 3·Recruiting·Listed Aug 2025
Assessment of CCM in HF With Higher Ejection Fraction
for Heart Failure
Sites in Detroit, Southfield +74 more locations
Sponsor: Impulse Dynamics
Sex: All·Age: 18+
Code: NCT05064709·Recruiting·Listed Oct 2021
BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
for Hypertension
Sites in Detroit, Ypsilanti +54 more locations
Sponsor: Orchestra BioMed, Inc
Sex: All·Age: 18+
Code: NCT06059638·Recruiting·Listed Sep 2023
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
for Heart Failure
Sites in Detroit +31 more locations
Sponsor: Procyrion
Sex: All·Age: 21+
Code: NCT05677100·Recruiting·Listed Jan 2023
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
for Heart Failure With Preserved Ejection Fraction
Sites in Detroit, Rochester Hills +108 more locations
Sponsor: Amgen
Sex: All·Age: 18 - 99
Code: NCT07037459·Phase 3·Recruiting·Listed Jun 2025
DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombosis
for Venous Thromboembolism
Sites in Detroit, Bay City +31 more locations
Sponsor: Inari Medical
Sex: All·Age: 18+
Code: NCT05701917·Recruiting·Listed Jan 2023
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
for Amyloidosis
Drug: Acoramidis
Sites in Detroit +39 more locations
Sponsor: Eidos Therapeutics, a BridgeBio company
Sex: All·Age: 18 - 75
Code: NCT06563895·Phase 3·Recruiting·Listed Aug 2024
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
for Heart Failure
Sites in Detroit +82 more locations
Sponsor: Cytokinetics
Sex: All·Age: 18 - 85
Code: NCT06736574·Phase 3·Recruiting·Listed Dec 2024
THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension
for Hypertension
Sites in Detroit, Southfield +31 more locations
Sponsor: SoniVie Inc.
Sex: All·Age: 22 - 75
Code: NCT06559891·Recruiting·Listed Aug 2024
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
for Cardiovascular Diseases
Sites in Detroit, Ann Arbor +45 more locations
Sponsor: BrioHealth Solutions, Inc.
Sex: All·Age: 18 - 100
Code: NCT06310031·Recruiting·Listed Mar 2024
Global Paradise System US Post Approval Study
for Hypertension
Sites in Detroit +42 more locations
Sponsor: ReCor Medical, Inc.
Sex: All·Age: 18+
Code: NCT06297291·Recruiting·Listed Mar 2024
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
for Heart Failure
Sites in Detroit, Grand Rapids +55 more locations
Sponsor: Abbott Medical Devices
Sex: All·Age: 18+
Code: NCT06526195·Recruiting·Listed Jul 2024
The THOR IDE Study
for Peripheral Artery Disease
Sites in Detroit +28 more locations
Sponsor: Philips Clinical & Medical Affairs Global
Sex: All·Age: 18+
Code: NCT05916950·Recruiting·Listed Jun 2023
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
for Heart Failure
Drug: CDR132L
Sites in Detroit +24 more locations
Sponsor: Novo Nordisk A/S
Sex: All·Age: 40 - 84
Code: NCT06979362·Phase 2·Recruiting·Listed May 2025
Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)
for Coronary Artery Disease
Sites in Detroit +18 more locations
Sponsor: Supira Medical
Sex: All·Age: 18 - 90
Code: NCT07296744·Recruiting·Listed Dec 2025
Accuracy of a Cuffless Photoplethysmography (PPG) Chest-Patch Monitor for 24-hour Ambulatory Blood Pressure Monitoring (ABPM)
for Blood Pressure
Sites in Detroit +5 more locations
Sponsor: Biobeat Technologies Ltd.
Sex: All·Age: 18+
Code: NCT07240831·Recruiting·Listed Nov 2025
A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease
for Pulmonary Hypertension
Sites in Detroit +5 more locations
Sponsor: Pulnovo Medical, Inc.
Sex: All·Age: 18 - 85
Code: NCT07214376·Recruiting·Listed Oct 2025
The RADIANCE CED Study
for Hypertension
2 locations in Detroit
Sponsor: ReCor Medical, Inc.
Sex: All·Age: 65+
Code: NCT07231757·Recruiting·Listed Nov 2025
Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions
for Coronary Artery Disease
Sites in Detroit +9 more locations
Sponsor: Teleflex
Sex: All·Age: 18+
Code: NCT06779630·Recruiting·Listed Jan 2025
AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor
for Ventricular Ejection Fraction
Sites in Detroit +7 more locations
Sponsor: Peerbridge Health, Inc
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT06699056·Recruiting·Listed Nov 2024
The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation
for Atrial Fibrillation
Sites in Detroit, Royal Oak +85 more locations
Sponsor: Johns Hopkins University
Sex: All·Age: 22 - 85
Code: NCT05836987·Phase 3·Recruiting·Listed May 2023
The Fourth Left Atrial Appendage Occlusion Study
for Atrial Fibrillation
Sites in Detroit, Ann Arbor +45 more locations
Sponsor: Hamilton Health Sciences Corporation
Sex: All·Age: 18+
Code: NCT05963698·Recruiting·Listed Jul 2023
Vascular Trial Associated Registry Pilot
for Peripheral Arterial Disease
Sites in Detroit & Grand Rapids
Sponsor: Corewell Health West
Sex: All·Age: 45+
Code: NCT07076082·Phase 4·Recruiting·Listed Jul 2025
UPBEAT: Using Polygenic Scores to Guide BB Therapy in HF With Mildly Reduced EF
for Heart Failure
1 location in Detroit
Sponsor: David Lanfear
Sex: All·Age: 18 - 89
Code: NCT07054489·Recruiting·Listed Jul 2025
Project 4: ACHIEVE PATHFINDER
for Heart Failure
1 location in Detroit
Sponsor: Henry Ford Health System
Sex: All·Age: 18+
Code: NCT06070428·Recruiting·Listed Oct 2023
Project 2: ACHIEVE- HF
for Heart Failure
1 location in Detroit
Sponsor: Henry Ford Health System
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT05330221·Recruiting·Listed Apr 2022
Promote Weight Loss in Obese Peripheral Artery Disease (PAD) Patients to Prevent Mobility Loss
for Peripheral Artery Disease
Sites in Detroit +5 more locations
Sponsor: Northwestern University
Sex: All·Age: 18+
Code: NCT04228978·Recruiting·Listed Jan 2020
ATrial Tachycardia PAcing Therapy in Congenital Heart
for Atrial Arrhythmia
Sites in Detroit, Ann Arbor +12 more locations
Sponsor: Ian Law
Sex: All·Age: All ages
Code: NCT03209583·Recruiting·Listed Jul 2017
Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk
for Peripheral Arterial Disease
Sites in Detroit +18 more locations
Sponsor: Population Health Research Institute
Sex: All·Age: 18+
Code: NCT04774159·Phase 3·Recruiting·Listed Mar 2021
Multi-Center Registry for Peripheral Arterial Disease Interventions and Outcomes
for Peripheral Arterial Disease
Sites in Detroit +6 more locations
Sponsor: Baylor Research Institute
Sex: All·Age: All ages
Code: NCT01904851·Recruiting·Listed Jul 2013
Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation
for Heart Failure
Sites in Detroit +3 more locations
Sponsor: University of Pennsylvania
Sex: All·Age: 18+
Code: NCT06291922·Recruiting·Listed Mar 2024
Perioperative Anticoagulant Use for Surgery Evaluation -2 (PAUSE-2) Study Patients Receiving a Direct Oral Anticoagulant (DOACs-Dabigatran, Rivaroxaban, Apixaban or Edoxaban) and Needing Elective High-Bleed-Risk Surgery or an Invasive Procedure
for Atrial Fibrillation (AF)
Sites in Detroit +5 more locations
Sponsor: McMaster University
Sex: All·Age: 18+
Code: NCT06957366·Recruiting·Listed May 2025
Addressing Cardiometabolic Health In Populations Through Early Prevention in the Great Lakes Region Project 1 - Epidemiology (ACHIEVE P1-EPI)
for Hypertension
1 location in Detroit
Sponsor: Wayne State University
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT06593496·Recruiting·Listed Sep 2024
Pulmonary Hypertension Association Registry
for Pulmonary Arterial Hypertension
Sites in Detroit +51 more locations
Sponsor: Pulmonary Hypertension Association, Inc.
Sex: All·Age: 0+
Code: NCT04071327·Recruiting·Listed Aug 2019
Perioperative Anticoagulant Use for Surgery Evaluation -Virtual Visit (PAUSE-Virtual)
for Atrial Fibrillation (AF)
Sites in Detroit +3 more locations
Sponsor: McMaster University
Sex: All·Age: 18 - 100
Code: NCT06844227·Recruiting·Listed Feb 2025
A Study of LY3971297 in Participants With Heart Failure
for Heart Failure
Drug: LY3971297
Sites in Detroit +3 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18 - 65
Code: NCT07547540·Phase 1·Recruiting·Listed Apr 2026
A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
for Cardiovascular Disease
Drug: AZD0780
Sites in Detroit, Dearborn Heights +308 more locations
Sponsor: AstraZeneca
Sex: All·Age: 18+
Code: NCT07000357·Phase 3·Recruiting·Listed Jun 2025
Prospective Global Registry for the Study of Chronic Total Occlusion Intervention
for Coronary Artery Disease
Sites in Detroit +32 more locations
Sponsor: Minneapolis Heart Institute Foundation
Sex: All·Age: All ages
Code: NCT02061436·Recruiting·Listed Feb 2014
Top Research Study Locations in Detroit
Researchers run research studies in Detroit, MI at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Henry Ford Hospital | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Heart Failure | 132 |
| Karmanos Cancer Institute | Ovarian Cancer, Advanced Solid Tumor, Endometrial Cancer | 88 |
| Henry Ford Health System | Advanced Solid Tumor, Brain Tumor, Breast Cancer | 68 |
| Henry Ford Health | Heart Failure, Advanced Solid Tumor, Amyotrophic Lateral Sclerosis | 58 |
| Children's Hospital of Michigan | Acute Myeloid Leukemia, Down Syndrome, Malignant Solid Neoplasm | 38 |
| Henry Ford Health Saint John Hospital | Anatomic Stage II Breast Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 35 |
| Wayne State University/Karmanos Cancer Institute | Stage II Lip and Oral Cavity Cancer AJCC v8, Stage III Laryngeal Cancer AJCC v8, Stage III Lip and Oral Cavity Cancer AJCC v8 | 30 |
| Wayne State University | Asthma, Benign Prostatic Hyperplasia, Cancer Support | 19 |
| Barbara Ann Karmanos Cancer Institute | Breast Neoplasms, Colorectal Neoplasms, Esophageal Neoplasms | 14 |
| Henry Ford Cancer Institute | Metastatic Solid Tumor, Locally Advanced Solid Tumor, AML | 12 |
| John D. Dingell VA Medical Center, Detroit, MI | Obstructive Sleep Apnea, Sleep Apnea, Sleep Disordered Breathing | 12 |
| GSK Investigational Site | Neoplasms, Colonic Neoplasms, Liver Diseases, Alcoholic | 8 |
| Karmanos Cancer Center | Breast Neoplasms, Cancer Weight Loss, Chronic Lymphocytic Leukemia (CLL) | 7 |
| Henry Ford Health Hospital | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 6 |
| Tolan Park Medical Building | PTSD, Polysubstance Abuse, Adolescence | 6 |
| Detroit Medical Center | Diabetes (DM), Diabetic Ketoacidosis, Gastric Emptying | 5 |
| Henry Ford | ADHF, Atrial Fibrillation (AF), Brain Tumor - Metastatic | 5 |
| Detroit Receiving Hospital | Traumatic Brain Injury, Lumbar Spinal Stenosis, Status Epilepticus | 4 |
| Henry Ford Cancer - Detroit (Brigitte Harris Cancer Pavilion) | Advanced Colorectal Cancer (Part 1), Glioma, KRAS G12C-mutated Solid Tumors, Lung Cancer | 4 |
| Henry Ford Cancer Center | Locally Advanced Solid Tumor, Hemoglobinopathy, Metastatic Solid Tumor | 4 |
| Henry Ford Medical Center | Acute Kidney Injury, Coronary Artery Disease, Healthy | 4 |
| Henry Ford St. John Hospital | Cardiovascular Diseases, Hypertension, Vascular Diseases | 4 |
| Ascension Saint John Hospital | Anatomic Stage IV Breast Cancer AJCC v8, Elevated CA15-3 or CEA or CA27-29, Estrogen Receptor Positive | 3 |
| Ascension St. John Hospital | High-Risk Percutaneous Coronary Intervention, Pulmonary Embolism, Right Ventricular (RV) Dysfunction | 3 |
| Brigitte Harris Cancer Pavilion | Glioma, Melanoma, Thyroid Cancer | 3 |
Active & Upcoming Studies in Detroit (2026)
Recruiting trials in Detroit grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (305 active studies)
- Perioperative Cemiplimab for Resectable Non-Small Cell Lung Cancer With High PD-L1 · Phase 2 · Henry Ford Health System
- A Study of the TheraBionic P1 Device in Breast Cancer · Barbara Ann Karmanos Cancer Institute
Cardiovascular (51 active studies)
- Emergency Department-Initiated Team-Based Care for Severe Hypertension · Henry Ford Health System
- A Study to Test How Well BAY 3670549 Works and How Safe it is in Patients With Atrial Fibrillation · Phase 2 · Bayer
Neurology & pain (26 active studies)
- Behavioral Optimization to Overcome Obstructive Sleep Apnea Treatment Barriers · VA Office of Research and Development
- Central Apnea in Heart Failure: Physiological Mechanisms to Inform Treatment · Phase 4 · VA Office of Research and Development
Diabetes & metabolic (14 active studies)
- Effects of Peanut Consumption on Adults With Metabolic Associated Fatty Liver Disease · Henry Ford Health System
- Safety Evaluation of MODI, an Insulin Titration Algorithm, in Adults With Diabetes · DreaMed Diabetes
Mental health & behavior (11 active studies)
- Understanding Non-invasive Vagus Nerve Stimulation Effects in PTSD · EARLY_Phase 1 · Wayne State University
- Wayne State Warriors Marijuana Clinical Research Program: Cannabinoid Adjunct to Prolonged Exposure & Recovery · Phase 1, Phase 2 · Leslie Lundahl
HIV / STI (4 active studies)
- Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention · Gilead Sciences
- A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062) · Phase 2, Phase 3 · Merck Sharp & Dohme LLC
Vaccines (3 active studies)
- A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised · Phase 3 · Pfizer
- Predictors of Post-COVID-19 Clinical and Cognitive Consequences · VA Office of Research and Development
Eye & vision (3 active studies)
- Comparison of Goniotomy Device Outcomes in Combined Phacoemulsification-goniotomy Surgeries · Henry Ford Health System
- Community Based Treatment for (ComBaT) Glaucoma · University of Michigan
Pediatric (3 active studies)
- Optimizing Pain Treatment in Children On Mechanical Ventilation · Phase 3 · Weill Medical College of Cornell University
- Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS · Phase 2, Phase 3 · Nationwide Children's Hospital
Common conditions studied in Detroit
- Endometrial Cancer (14 active studies)
- Advanced Solid Tumor (13 active studies)
- Breast Cancer (13 active studies)
- Heart Failure (13 active studies)
- Multiple Myeloma (12 active studies)
- Ovarian Cancer (12 active studies)
Leading research sponsors in Detroit
- Henry Ford Health System
- National Cancer Institute (NCI)
- AstraZeneca
- Wayne State University
- SWOG Cancer Research Network
Frequently asked questions
How many paid clinical trials are currently recruiting in Detroit?
There are approximately 718 recruiting clinical trials in Detroit, Michigan listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Detroit pay participants?
Most recruiting trials in Detroit compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Detroit?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Detroit?
The most common conditions under active study in Detroit include Endometrial Cancer (14), Advanced Solid Tumor (13), Breast Cancer (13), Heart Failure (13), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Detroit?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Detroit on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Detroit?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Detroit?
Recruiting research sites in Detroit include Henry Ford Hospital, Karmanos Cancer Institute, Henry Ford Health System, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Detroit right now?
The largest active categories in Detroit are Cancer & tumors (305), Cardiovascular (51), Neurology & pain (26). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
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