Paid Clinical Trials in Royal Oak, MI
As of July 2026, 103 paid clinical trials are recruiting in Royal Oak, Michigan. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Royal Oak offers studies at sites including Corewell Health William Beaumont University Hospital for conditions such as Breast Cancer, Acute Myeloid Leukemia, Advanced Breast Cancer, Coronary Artery Disease. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Royal Oak
Trials by drug in Royal Oak
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96 clinical trials
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
Randomized Study in Children and Adolescents With Migraine: Acute Treatment
Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine
Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study
A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)
Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD
Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)
A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%
An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.
VE303 for Prevention of Recurrent Clostridioides Difficile Infection
A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System
Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis
Nectero EAST System Clinical Study
The PREDICT Registry:
Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC
A Study to Investigate Subcutaneous Isatuximab in Combination With Weekly Carfilzomib and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma
A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)
A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)
A Trial to Evaluate Ovarian Suppression Following Subcutaneous ZOLADEX 10.8 mg in Premenopausal Women With HR+, HER2- Advanced Breast Cancer
A Study to Evaluate TAR-210 Versus Intravesical Chemotherapy Treatment in Participants With High Risk Non-Muscle-Invasive Bladder Cancer
Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer
A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis
Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral Infection
AltaValve Pivotal Trial
C. Difficile Toxin Levels in Stool From Healthy Individuals Following Standard of Care Antibiotic Treatment for CDI.
Virtue® SAB in the Treatment of Coronary ISR Trial
Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors
Active Surveillance SNEP Assay Registry Trial for Prostate Cancer
A Study to Evaluate the Utilization of 3D Printed Models in Pre-Operative Planning
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Top Research Study Locations in Royal Oak
Researchers run research studies in Royal Oak, MI at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Corewell Health William Beaumont University Hospital | Stage IIIB Lung Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8 | 35 |
| Corewell Health Children's | Acute Myeloid Leukemia, Ganglioneuroblastoma, Nodular, Metastatic Osteosarcoma | 16 |
| William Beaumont Hospital | Aortic Stenosis, Aortic Valve Regurgitation, Aortic Valve Stenosis | 12 |
| Cancer Care Associates PC | Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Advanced Esophageal Adenocarcinoma | 6 |
| Comprehensive Medical Center PLLC | Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Advanced Esophageal Adenocarcinoma | 6 |
| Hematology Oncology Consultants PC-Royal Oak | Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Advanced Esophageal Adenocarcinoma | 6 |
| Oakland Colon Rectal Associates | Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Advanced Esophageal Adenocarcinoma | 6 |
| Oakland Medical Group | Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Advanced Esophageal Adenocarcinoma | 6 |
| Associated Retinal Consultants, P.C. | Age - Related Macular Degeneration (AMD), Geographic Atrophy (GA), Radiation Retinopathy | 3 |
| Beaumont Hospital, Royal Oak | Blood Loss, Surgical, Coagulation Disorder, Idiopathic Pulmonary Fibrosis | 3 |
| Comprehensive Urology | High-Risk Non-Muscle-Invasive Bladder Cancer, Non-Muscle Invasive Bladder Neoplasms, Prostate Cancer Aggressiveness | 3 |
| Beaumont Health | Abdominal Aortic Aneurysm, Shoulder Arthritis, Shoulder Disease | 2 |
| Corewell Health William Beaum Hosp | Gastroenteropancreatic Neuroendocrine Carcinoma, Large Cell Neuroendocrine Carcinoma of the Lung, Neuroendocrine Prostate Cancer | 2 |
| Profound Research LLC at Michigan Hematology and Oncology Consultants | Advanced Breast Cancer, Breast Neoplasms | 2 |
| Associated Retinal Consultants | AMD, CNV, Wet Age-related Macular Degeneration | 2 |
| Apex Surgl Ctr | Lumbar Spinal Stenosis | 1 |
| Associated Retinal Consultants (ARC) P.C. | Choroidal Melanoma, Indeterminate Lesions, Ocular Melanoma | 1 |
| Associated Retinal Consultants PC | Neovascular Age-related Macular Degeneration | 1 |
| Beaumont Breast Care Center | Breast Cancer | 1 |
| Beaumont Health Systems | Atrial Fibrillation | 1 |
| Beaumont Hospital - Royal Oak | Intravenous Infection, Peripheral Intravenous Vein Catheter Phlebitis | 1 |
| Beaumont Hospital Research Institute | Degenerative Disc Disease, Degenerative Scoliosis, Degenerative Spondylolisthesis | 1 |
| Beaumont Hospital Royal Oak Campus | Pediatric Migraine | 1 |
| Beaumont Hospital, Royal Oak Campus | Acute Treatment of Migraine | 1 |
| Beaumont University Hospital | Aortic Aneurysm, Abdominal | 1 |
Active & Upcoming Studies in Royal Oak (2026)
Recruiting trials in Royal Oak grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (49 active studies)
- A Trial to Evaluate Ovarian Suppression Following Subcutaneous ZOLADEX 10.8 mg in Premenopausal Women With HR+, HER2- Advanced Breast Cancer · Phase 1 · TerSera Therapeutics LLC
- Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors · Phase 1 · Novartis Pharmaceuticals
Cardiovascular (8 active studies)
- Virtue® SAB in the Treatment of Coronary ISR Trial · Orchestra BioMed, Inc
- Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258) · Phase 3 · Reprieve Cardiovascular, Inc
Neurology & pain (5 active studies)
- Sacral Neuromodulation for Chronic Pelvic Pain · Corewell Health East
- Magnesium and Cramping · Phase 4 · Corewell Health East
Eye & vision (4 active studies)
- Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD) · Phase 3 · AbbVie
- Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD · Phase 2 · ONL Therapeutics
Pediatric (1 active study)
- Randomized Study in Children and Adolescents With Migraine: Acute Treatment · Phase 3 · Pfizer
Common conditions studied in Royal Oak
- Breast Cancer (4 active studies)
- Acute Myeloid Leukemia (3 active studies)
- Advanced Breast Cancer (3 active studies)
- Coronary Artery Disease (3 active studies)
- Malignant Solid Neoplasm (3 active studies)
- Stage IIIB Lung Cancer AJCC v8 (3 active studies)
Leading research sponsors in Royal Oak
- National Cancer Institute (NCI)
- Children's Oncology Group
- Corewell Health East
- NRG Oncology
- Alliance for Clinical Trials in Oncology
Frequently asked questions
How many paid clinical trials are currently recruiting in Royal Oak?
There are approximately 103 recruiting clinical trials in Royal Oak, Michigan listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Royal Oak pay participants?
Most recruiting trials in Royal Oak compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Royal Oak?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Royal Oak?
The most common conditions under active study in Royal Oak include Breast Cancer (4), Acute Myeloid Leukemia (3), Advanced Breast Cancer (3), Coronary Artery Disease (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Royal Oak?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Royal Oak on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Royal Oak?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Royal Oak?
Recruiting research sites in Royal Oak include Corewell Health William Beaumont University Hospital, Corewell Health Children's, William Beaumont Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Royal Oak right now?
The largest active categories in Royal Oak are Cancer & tumors (49), Cardiovascular (8), Neurology & pain (5). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.