Paid Clinical Trials in Southfield, MI
As of September 2026, 70 paid clinical trials are recruiting in Southfield, Michigan. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Southfield offers studies at sites including Henry Ford Health Providence Southfield Hospital for conditions such as Obesity, Overweight, Degenerative Disc Disease, Anatomic Stage II Breast Cancer AJCC v8. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Southfield
Trials by drug in Southfield
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Newly added in Southfield
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes
Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older
63 clinical trials
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).
A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
Assessment of CCM in HF With Higher Ejection Fraction
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II
A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma
THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH
A Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia
A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Narcolepsy
A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Idiopathic Hypersomnia (IH)
A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight
A Study to Evaluate the Efficacy and Safety of E2086 in Adults With Narcolepsy
A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCD
A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity
SPYRAL GEMINI Pilot Study
Persona Revision Knee System Outcomes
Clinical Outcome Measure at Stryker Spine
Evaluation of Safety and Effectiveness of Primary Hybrid Construct of Mobi-C and ACDF in the Treatment of Two-level Symptomatic Degenerative Disc Disease in the Cervical Spine.
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study
Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
Top Research Study Locations in Southfield
Researchers run research studies in Southfield, MI at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Henry Ford Health Providence Southfield Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 21 |
| Michigan Orthopaedic Surgeons | Degenerative Disc Disease, Degenerative Scoliosis, Disc Herniation | 5 |
| Revive Research Institute, Inc. | Obesity, Overweight, Clostridoides Difficile Associated Disease | 5 |
| Henry Ford Providence Hospital | Heart Failure, Hypertension, Cardiovascular Diseases | 4 |
| Great Lakes Research Institute | Overweight, Metabolic Dysfunction-Associated Steatotic Liver Disease, Obesity | 3 |
| Headlands Research - Detroit | Obesity, Overweight | 3 |
| DM Clinical Research - Detroit | Clostridoides Difficile Associated Disease, Healthy Volunteers, Human Metapneumovirus Immunization | 2 |
| AURORA-2 Clinical Site | Chronic Weight Management, Obesity, Overweight | 1 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, NASH - Nonalcoholic Steatohepatitis | 1 |
| Ascension Providence Hospital | Diastolic Heart Failure, Heart Failure, Heart Failure With Mid Range Ejection Fraction | 1 |
| Ascension Providence Hospitals - Southfield | Cardiotoxicity, HER2/Neu Positive, Metastatic Malignant Neoplasm in the Brain | 1 |
| Clinical Trial Site | High Cardiovascular Risk, High Risk Cardiovascular Disease, Hypertension | 1 |
| Enveda Investigative Site | Asthma | 1 |
| Great Lakes Research Inst. | Diabetes Mellitus, Type 2 | 1 |
| Great Lakes Research Institute -Southfield | SARS-CoV-2 | 1 |
| Great Lakes Research Institute, Flourish Detroit | Sickle Cell Disease | 1 |
| Great Lakes Surgical Center | Lumbar Spinal Stenosis | 1 |
| Henry Ford Health System | Heart Failure, Obesity | 1 |
| Henry Ford Providence | Refractory Angina | 1 |
| Henry Ford Providence Southfield CK Potluri Cancer Center | Multiple Myeloma | 1 |
| Michigan Orthopaedic Surgeons, PLLC | Arthroplasty Complications, Infection, Knee Disease | 1 |
| Michigan Orthopedic Surgeons | Degenerative Disc Disease | 1 |
| Northwest Neurology | Multiple Sclerosis Spasticity | 1 |
| Revival Research Institute | Cardiovascular Disease | 1 |
| Revival Research Institute, LLC | Alzheimer Disease, Dementia, Plaque, Amyloid | 1 |
Active & Upcoming Studies in Southfield (2026)
Recruiting trials in Southfield grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (22 active studies)
- ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab · Phase 3 · Alliance for Clinical Trials in Oncology
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
Diabetes & metabolic (13 active studies)
- A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity · Phase 3 · Eli Lilly and Company
- A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes · Phase 3 · Ascletis Pharma (China) Co., Limited
Cardiovascular (8 active studies)
Neurology & pain (3 active studies)
- A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT). · Phase 3 · Eli Lilly and Company
- A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight · Phase 3 · Eli Lilly and Company
Vaccines (2 active studies)
- A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1283 in Participants ≥6 Months to <12 Years of Age · Phase 2 · ModernaTX, Inc.
- Phase 1/2 Study of Respiratory Syncytial Virus and Human Metapneumovirus (RSV+HMPV) Vaccine Candidate in Adults 60 Years of Age and Older · Phase 1, Phase 2 · Sanofi
Mental health & behavior (1 active study)
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
Common conditions studied in Southfield
- Obesity (7 active studies)
- Overweight (7 active studies)
- Degenerative Disc Disease (5 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (4 active studies)
- Heart Failure (4 active studies)
- Hypertension (3 active studies)
Leading research sponsors in Southfield
- National Cancer Institute (NCI)
- Eli Lilly and Company
- AstraZeneca
- NRG Oncology
- SWOG Cancer Research Network
Frequently asked questions
How many paid clinical trials are currently recruiting in Southfield?
There are approximately 70 recruiting clinical trials in Southfield, Michigan listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Southfield pay participants?
Most recruiting trials in Southfield compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Southfield?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Southfield?
The most common conditions under active study in Southfield include Obesity (7), Overweight (7), Degenerative Disc Disease (5), Anatomic Stage II Breast Cancer AJCC v8 (4), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Southfield?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Southfield on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Southfield?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Southfield?
Recruiting research sites in Southfield include Henry Ford Health Providence Southfield Hospital, Michigan Orthopaedic Surgeons, Revive Research Institute, Inc., among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Southfield right now?
The largest active categories in Southfield are Cancer & tumors (22), Diabetes & metabolic (13), Cardiovascular (8). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.