Paid Clinical Trials in Novi, MI
As of September 2026, 71 paid clinical trials are recruiting in Novi, Michigan. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Novi offers studies at sites including Henry Ford Medical Center-Columbus for conditions such as Anatomic Stage II Breast Cancer AJCC v8, Acute Myeloid Leukemia, Anatomic Stage IIIA Breast Cancer AJCC v8, Lung Non-Small Cell Carcinoma. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Novi
Trials by drug in Novi
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Newly added in Novi
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
A Study to Investigate the Efficacy and Safety of Apraglutide Compared With Placebo in Adult Participants With Short Bowel Syndrome Associated With Intestinal Failure (SBS-IF)
68 clinical trials
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma
RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease
A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH
A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis
Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein
CCM OPEN HF Registry
A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Narcolepsy
RE104 Safety and Efficacy Study in Generalized Anxiety Disorder
A Study to Evaluate the Efficacy and Safety of E2086 in Adults With Narcolepsy
A Pivotal Study to Evaluate the Clinical Benefit, Performance and Safety of a Totally Implantable Cochlear Implant (TICI) System in Adults
Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)
A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions
Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma
Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation
Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study
Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial
MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)
Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer
Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma
A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab
Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial
Top Research Study Locations in Novi
Researchers run research studies in Novi, MI at 18 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Henry Ford Medical Center-Columbus | Anatomic Stage II Breast Cancer AJCC v8, Acute Myeloid Leukemia, Anatomic Stage IIIA Breast Cancer AJCC v8 | 39 |
| Henry Ford Health Providence Novi Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 18 |
| Henry Ford Medical Center - Columbus | Alpha1-Antitrypsin Deficiency, Generalized Anxiety Disorder, Narcolepsy | 7 |
| Henry Ford Columbus Medical Center | Nightshift Work, Shift Work Sleep Disorder, Shift-work Disorder | 3 |
| Henry Ford Medical Center | Insomnia, Cataplexy, Depression | 3 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, MASH With Fibrosis, NASH - Nonalcoholic Steatohepatitis | 2 |
| Alkermes Investigational Site | Narcolepsy Type 1, Narcolepsy Type 2 | 2 |
| Corazon Imaging | Atherosclerosis, Cardiovascular Inflammation, Coronary Artery Disease | 1 |
| Henry Ford | Castration-Resistant Prostate Cancer, Castration-Resistant Prostate Cancer (CRPC), Prostate Cancer | 1 |
| Henry Ford Health | Adjustment Disorder | 1 |
| Henry Ford Health System | Alpha1-Antitrypsin Deficiency | 1 |
| Henry Ford Health System - Columbus | Lumbar Spinal Stenosis | 1 |
| Henry Ford Providence Hospital | Heart Failure | 1 |
| Henry Ford Providence Novi Hospital | Multiple Myeloma | 1 |
| Iinn Novi | Lumbar Spinal Stenosis | 1 |
| Michigan Ear Institute | Hearing Loss, Bilateral Sensorineural | 1 |
| Michigan Outpatient Surgical Solutions | Lumbar Spinal Stenosis | 1 |
| Novi Surgery Center | Lumbar Spinal Stenosis | 1 |
Active & Upcoming Studies in Novi (2026)
Recruiting trials in Novi grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (44 active studies)
- Study of Oral MRT-2359 With Apalutamide in Prostate Cancer · Phase 2 · Monte Rosa Therapeutics, Inc
- Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial · Phase 3 · National Cancer Institute (NCI)
Mental health & behavior (3 active studies)
- RE104 Safety and Efficacy Study in Generalized Anxiety Disorder · Phase 2 · Reunion Neuroscience Inc
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
Diabetes & metabolic (2 active studies)
- A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH · Phase 3 · Akero Therapeutics, Inc
- A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis · Phase 3 · Akero Therapeutics, Inc
Neurology & pain (2 active studies)
- The Use of Multiple Sensors to Track Sleep in Nightshift Workers · Henry Ford Health System
- A Pilot of a Personalized Circadian mHealth to Improve Sleep in Night Shift Workers · Henry Ford Health System
Cardiovascular (2 active studies)
- CaRi-Heart Assessment of Risk and Evaluation of Inflammation in Coronary CT Angiography (CARE-CCTA) · Corazon Medical PC
- CCM OPEN HF Registry · Impulse Dynamics
Common conditions studied in Novi
- Anatomic Stage II Breast Cancer AJCC v8 (5 active studies)
- Acute Myeloid Leukemia (3 active studies)
- Anatomic Stage IIIA Breast Cancer AJCC v8 (3 active studies)
- Lung Non-Small Cell Carcinoma (3 active studies)
- Alpha1-Antitrypsin Deficiency (2 active studies)
- Anatomic Stage I Breast Cancer AJCC v8 (2 active studies)
Leading research sponsors in Novi
- National Cancer Institute (NCI)
- NRG Oncology
- SWOG Cancer Research Network
- Alliance for Clinical Trials in Oncology
- Henry Ford Health System
Frequently asked questions
How many paid clinical trials are currently recruiting in Novi?
There are approximately 71 recruiting clinical trials in Novi, Michigan listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Novi pay participants?
Most recruiting trials in Novi compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Novi?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Novi?
The most common conditions under active study in Novi include Anatomic Stage II Breast Cancer AJCC v8 (5), Acute Myeloid Leukemia (3), Anatomic Stage IIIA Breast Cancer AJCC v8 (3), Lung Non-Small Cell Carcinoma (3), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Novi?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Novi on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Novi?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Novi?
Recruiting research sites in Novi include Henry Ford Medical Center-Columbus, Henry Ford Health Providence Novi Hospital, Henry Ford Medical Center - Columbus, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Novi right now?
The largest active categories in Novi are Cancer & tumors (44), Mental health & behavior (3), Diabetes & metabolic (2). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.