MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
for Lumbar Spinal Stenosis
Sites in Novi, Plymouth +2341 more locations
Sponsor: Stryker Instruments
Sex: All·Age: 18+
Code: NCT03072927·Recruiting·Listed Mar 2017
Paid Clinical Trials in Novi, MI
As of July 2026, 71 paid clinical trials are recruiting in Novi, Michigan. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Novi offers studies at sites including Henry Ford Medical Center-Columbus for conditions such as Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Lung Non-Small Cell Carcinoma, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Novi
Trials by drug in Novi
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69 clinical trials
Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease
for Crohn's Disease
Sites in Novi +55 more locations
Sponsor: AbbVie
Sex: All·Age: 18 - 75
Code: NCT06548542·Phase 2·Recruiting·Listed Aug 2024
A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma
for Multiple Myeloma
Drug: Daratumumab
Sites in Novi, Southfield +64 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 18+
Code: NCT05552222·Phase 3·Recruiting·Listed Sep 2022
A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.
for Melanoma
Sites in Novi, Plymouth +29 more locations
Sponsor: Pfizer
Sex: All·Age: 16+
Code: NCT05355701·Phase 1·Recruiting·Listed May 2022
RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
for Adjustment Disorder
Sites in Novi, Ann Arbor +28 more locations
Sponsor: Reunion Neuroscience Inc
Sex: All·Age: 18 - 80
Code: NCT07002034·Phase 2·Recruiting·Listed Jun 2025
A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis
for NASH With Fibrosis
Drug: Efruxifermin
Sites in Novi, Wyoming +172 more locations
Sponsor: Akero Therapeutics, Inc
Sex: All·Age: 18 - 80
Code: NCT06215716·Phase 3·Recruiting·Listed Jan 2024
A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH
for NASH - Nonalcoholic Steatohepatitis
Drug: Efruxifermin
Sites in Novi, Southfield +153 more locations
Sponsor: Akero Therapeutics, Inc
Sex: All·Age: 18 - 80
Code: NCT06528314·Phase 3·Recruiting·Listed Jul 2024
CCM OPEN HF Registry
for Heart Failure
Sites in Novi, Ypsilanti +26 more locations
Sponsor: Impulse Dynamics
Sex: All·Age: 18+
Code: NCT07112924·Recruiting·Listed Aug 2025
Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein
for Alpha1-Antitrypsin Deficiency
Sites in Novi, Ann Arbor +31 more locations
Sponsor: Takeda
Sex: All·Age: 18 - 75
Code: NCT05677971·Phase 3·Recruiting·Listed Jan 2023
RE104 Safety and Efficacy Study in Generalized Anxiety Disorder
for Generalized Anxiety Disorder
Sites in Novi +21 more locations
Sponsor: Reunion Neuroscience Inc
Sex: All·Age: 18 - 74
Code: NCT07489651·Phase 2·Recruiting·Listed Mar 2026
A Study to Evaluate the Efficacy and Safety of E2086 in Adults With Narcolepsy
for Narcolepsy
Sites in Novi, Southfield +15 more locations
Sponsor: Eisai Inc.
Sex: All·Age: 18+
Code: NCT07493265·Phase 2·Recruiting·Listed Mar 2026
A Pivotal Study to Evaluate the Clinical Benefit, Performance and Safety of a Totally Implantable Cochlear Implant (TICI) System in Adults
for Hearing Loss, Bilateral Sensorineural
Sites in Novi +10 more locations
Sponsor: Cochlear
Sex: All·Age: 18+
Code: NCT07287124·Recruiting·Listed Dec 2025
Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)
for Alpha1-Antitrypsin Deficiency
Sites in Novi, Ann Arbor +18 more locations
Sponsor: Takeda
Sex: All·Age: 18 - 75
Code: NCT06165341·Phase 3·Recruiting·Listed Dec 2023
A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions
for Narcolepsy Type 1
Sites in Novi +18 more locations
Sponsor: Takeda
Sex: All·Age: 16 - 70
Code: NCT05816382·Phase 2, Phase 3·Recruiting·Listed Apr 2023
Virtual Reality for Caregiver Assembly, Relief, Empowerment, and Support (VR-CARES)
for Direct Care Workers
Sites in Novi, Brighton +6 more locations
Sponsor: Rendever, Inc.
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07430371·Recruiting·Listed Feb 2026
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
for Lung Non-Small Cell Carcinoma
Sites in Novi, Farmington Hills +633 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
for Breast Cancer
Sites in Novi, Farmington Hills +1103 more locations
Sponsor: NRG Oncology
Sex: Female·Age: 18 - 60
Code: NCT05879926·Phase 3·Recruiting·Listed May 2023
Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial
for Advanced Hepatocellular Carcinoma
Sites in Novi, West Bloomfield +136 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT07166406·Phase 3·Recruiting·Listed Sep 2025
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
for Stage III Colon Cancer
Sites in Novi, Livonia +920 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021
Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab
for Anatomic Stage II Breast Cancer AJCC v8
Sites in Novi, Livonia +774 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT05812807·Phase 3·Recruiting·Listed Apr 2023
Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study
for Chronic Lymphocytic Leukemia
Sites in Novi, Livonia +296 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04269902·Phase 3·Recruiting·Listed Feb 2020
Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas
for Intracranial Meningioma
Sites in Novi, Livonia +454 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT02523014·Phase 2·Recruiting·Listed Aug 2015
Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery
for Head and Neck Squamous Cell Carcinoma
Sites in Novi, Farmington Hills +464 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT02734537·Phase 2·Recruiting·Listed Apr 2016
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
for Anatomic Stage I Breast Cancer AJCC v8
Sites in Novi, Livonia +583 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 18+
Code: NCT06876714·Phase 3·Recruiting·Listed Mar 2025
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
for Acute Lymphoblastic Leukemia
Sites in Novi, Farmington Hills +629 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 40 - 75·Accepts healthy volunteers
Code: NCT05334069·Recruiting·Listed Apr 2022
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
for Anatomic Stage II Breast Cancer AJCC v8
Drug: Durvalumab
Sites in Novi, Farmington Hills +525 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06058377·Phase 3·Recruiting·Listed Sep 2023
Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial
for Extensive Stage Lung Small Cell Carcinoma
Drug: Atezolizumab
Sites in Novi, Farmington Hills +271 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04402788·Phase 2, Phase 3·Recruiting·Listed May 2020
Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study
for Muscle Invasive Bladder Urothelial Carcinoma
Sites in Novi, Farmington Hills +445 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT05987241·Phase 2, Phase 3·Recruiting·Listed Aug 2023
Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma
for Smoldering Plasma Cell Myeloma
Drug: Daratumumab
Sites in Novi, Livonia +486 more locations
Sponsor: ECOG-ACRIN Cancer Research Group
Sex: All·Age: 18+
Code: NCT03937635·Phase 3·Recruiting·Listed May 2019
APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation
for Pancreatic Acinar Cell Carcinoma
Drug: Olaparib
Sites in Novi, Farmington Hills +258 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04858334·Phase 2·Recruiting·Listed Apr 2021
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
for Bladder Adenocarcinoma
Drug: Cabozantinib
Sites in Novi, Livonia +223 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT03866382·Phase 2·Recruiting·Listed Mar 2019
MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)
for Acute Myeloid Leukemia
Sites in Novi, Farmington Hills +326 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT05564390·Phase 2·Recruiting·Listed Oct 2022
Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response
for Prostate Cancer (Adenocarcinoma)
Sites in Novi, Farmington Hills +357 more locations
Sponsor: Canadian Cancer Trials Group
Sex: Male·Age: 18+
Code: NCT06592924·Phase 3·Recruiting·Listed Sep 2024
A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab
for Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8
Drug: Nivolumab
Sites in Novi, Farmington Hills +374 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 5 - 60
Code: NCT05675410·Phase 3·Recruiting·Listed Jan 2023
Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial
for Lung Non-Small Cell Carcinoma
Sites in Novi, Livonia +262 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT06498635·Phase 3·Recruiting·Listed Jul 2024
E-Mindfulness Approaches for Living After Breast Cancer
for Breast Cancer
Sites in Novi, West Bloomfield +355 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18 - 50
Code: NCT06748222·Phase 3·Recruiting·Listed Dec 2024
Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer
for Previously Treated Non-Small Cell Lung Cancer
Sites in Novi, Livonia +948 more locations
Sponsor: SWOG Cancer Research Network
Sex: All·Age: 18+
Code: NCT03851445·Phase 2, Phase 3·Recruiting·Listed Feb 2019
Testing Osimertinib as a Treatment for Lung Cancers With an EGFR Exon 20 Change
for Advanced Lung Non-Small Cell Carcinoma
Drug: Osimertinib
Sites in Novi, Livonia +217 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT03191149·Phase 2·Recruiting·Listed Jun 2017
Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer
for Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma
Sites in Novi, Livonia +314 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT06958328·Phase 3·Recruiting·Listed May 2025
Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
for Locally Advanced Lung Non-Small Cell Carcinoma
Sites in Novi, Farmington Hills +444 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT05624996·Phase 3·Recruiting·Listed Nov 2022
Top Research Study Locations in Novi
Researchers run research studies in Novi, MI at 17 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Henry Ford Medical Center-Columbus | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm | 42 |
| Henry Ford Health Providence Novi Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 20 |
| Henry Ford Medical Center - Columbus | Advanced Colorectal Cancer (Part 1), Alpha1-Antitrypsin Deficiency, Generalized Anxiety Disorder | 7 |
| Henry Ford Columbus Medical Center | Nightshift Work, Shift Work Sleep Disorder, Shift-work Disorder | 3 |
| Akero Clinical Study Site | MASH - Metabolic Dysfunction-Associated Steatohepatitis, MASH With Fibrosis, NASH - Nonalcoholic Steatohepatitis | 2 |
| Henry Ford Medical Center | Insomnia, Depression, Menopausal Women | 2 |
| Corazon Imaging | Atherosclerosis, Cardiovascular Inflammation, Coronary Artery Disease | 1 |
| Henry Ford Health | Adjustment Disorder | 1 |
| Henry Ford Health System | Alpha1-Antitrypsin Deficiency | 1 |
| Henry Ford Health System - Columbus | Lumbar Spinal Stenosis | 1 |
| Henry Ford Providence Hospital | Heart Failure | 1 |
| Henry Ford Providence Novi Hospital | Multiple Myeloma | 1 |
| Iinn Novi | Lumbar Spinal Stenosis | 1 |
| Michigan Ear Institute | Hearing Loss, Bilateral Sensorineural | 1 |
| Michigan Outpatient Surgical Solutions | Lumbar Spinal Stenosis | 1 |
| Novi Surgery Center | Lumbar Spinal Stenosis | 1 |
| Right at Home | Caregiver Social Support, Dementia Caregiver, Direct Care Workers | 1 |
Active & Upcoming Studies in Novi (2026)
Recruiting trials in Novi grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (46 active studies)
- Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial · Phase 3 · NRG Oncology
- Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study · Phase 3 · NRG Oncology
Mental health & behavior (3 active studies)
- RE104 Safety and Efficacy Study in Generalized Anxiety Disorder · Phase 2 · Reunion Neuroscience Inc
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
Diabetes & metabolic (2 active studies)
- A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH · Phase 3 · Akero Therapeutics, Inc
- A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis · Phase 3 · Akero Therapeutics, Inc
Neurology & pain (2 active studies)
- The Use of Multiple Sensors to Track Sleep in Nightshift Workers · Henry Ford Health System
- A Pilot of a Personalized Circadian mHealth to Improve Sleep in Night Shift Workers · Henry Ford Health System
Cardiovascular (2 active studies)
- CaRi-Heart Assessment of Risk and Evaluation of Inflammation in Coronary CT Angiography (CARE-CCTA) · Corazon Medical PC
- CCM OPEN HF Registry · Impulse Dynamics
Common conditions studied in Novi
- Acute Myeloid Leukemia (6 active studies)
- Anatomic Stage II Breast Cancer AJCC v8 (4 active studies)
- Lung Non-Small Cell Carcinoma (3 active studies)
- Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm (2 active studies)
- Acute Myeloid Leukemia Post Cytotoxic Therapy (2 active studies)
- Acute Myeloid Leukemia, Myelodysplasia-Related (2 active studies)
Leading research sponsors in Novi
- National Cancer Institute (NCI)
- NRG Oncology
- SWOG Cancer Research Network
- Alliance for Clinical Trials in Oncology
- Henry Ford Health System
Frequently asked questions
How many paid clinical trials are currently recruiting in Novi?
There are approximately 71 recruiting clinical trials in Novi, Michigan listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Novi pay participants?
Most recruiting trials in Novi compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Novi?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Novi?
The most common conditions under active study in Novi include Acute Myeloid Leukemia (6), Anatomic Stage II Breast Cancer AJCC v8 (4), Lung Non-Small Cell Carcinoma (3), Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Novi?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Novi on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Novi?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Novi?
Recruiting research sites in Novi include Henry Ford Medical Center-Columbus, Henry Ford Health Providence Novi Hospital, Henry Ford Medical Center - Columbus, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Novi right now?
The largest active categories in Novi are Cancer & tumors (46), Mental health & behavior (3), Diabetes & metabolic (2). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
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