Symptom Management to Improve Completion of Patient-reported Outcome Measures
for Malignant Solid Neoplasm
1 location in Detroit
Sponsor: Henry Ford Health System
Sex: All·Age: 18+
Code: NCT07723495·Not Yet Recruiting·Listed Jul 23, 2026
Solid tumor Clinical Trials in Detroit, MI
As of September 2026, 52 paid clinical trials are recruiting for Solid tumor in Detroit, Michigan. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Detroit
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
53 clinical trials for Solid tumor
·Clear filters· Email me when a new solid tumor trial opens in Detroit, MI.
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
for Solid Tumors
Drug: INCB161734
Sites in Detroit, Ypsilanti +68 more locations
Sponsor: Incyte Corporation
Sex: All·Age: 18+
Code: NCT07522073·Phase 3·Recruiting·Listed Apr 2026
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
for Renal Cell Carcinoma (RCC)
Sites in Detroit +43 more locations
Sponsor: Exelixis
Sex: All·Age: 18+
Code: NCT05176483·Phase 1·Recruiting·Listed Jan 2022
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
for Solid Tumors
Sites in Detroit +41 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 18+
Code: NCT03486873·Phase 3·Recruiting·Listed Apr 2018
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
for Advanced Solid Tumor
Sites in Detroit +30 more locations
Sponsor: PMV Pharmaceuticals, Inc
Sex: All·Age: 12+
Code: NCT04585750·Phase 1, Phase 2·Recruiting·Listed Oct 2020
A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors
for Advanced Solid Tumors
Sites in Detroit +27 more locations
Sponsor: DualityBio Inc.
Sex: All·Age: 18+
Code: NCT05914116·Phase 1, Phase 2·Recruiting·Listed Jun 2023
A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors
for Advanced Solid Tumor
Sites in Detroit, Grand Rapids +16 more locations
Sponsor: BioNTech SE
Sex: All·Age: 18+
Code: NCT07070232·Phase 1, Phase 2·Recruiting·Listed Jul 2025
Safety, Pharmacokinetics, and Efficacy of AI-081, a Bispecific Antibody for PD-1 And VEGF in Advanced Solid Tumors
for Advanced Solid Tumor
Drug: AI-081
Sites in Detroit, Ann Arbor +19 more locations
Sponsor: OncoC4, Inc.
Sex: All·Age: 18+
Code: NCT06635785·Phase 1, Phase 2·Recruiting·Listed Oct 2024
A Study of ASP1002 in Adults for Treatment of Solid Tumors
for Advanced Solid Tumors
Sites in Detroit +11 more locations
Sponsor: Astellas Pharma Global Development, Inc.
Sex: All·Age: 18+
Code: NCT05719558·Phase 1·Recruiting·Listed Feb 2023
A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors
for Metastatic Solid Tumor
Sites in Detroit +17 more locations
Sponsor: Coherus Oncology, Inc.
Sex: All·Age: 18+
Code: NCT06657144·Phase 1·Recruiting·Listed Oct 2024
A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
for Advanced Solid Tumors
Sites in Detroit +9 more locations
Sponsor: Marengo Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT05592626·Phase 1, Phase 2·Recruiting·Listed Oct 2022
A Study of 177Lu-FAP-2286 in Advanced Solid Tumors
for Solid Tumor
Sites in Detroit +19 more locations
Sponsor: Novartis Pharmaceuticals
Sex: All·Age: 18+
Code: NCT04939610·Phase 1, Phase 2·Recruiting·Listed Jun 2021
A Study of ZL-1310 in Participants With Selected Solid Tumors
for Solid Tumors
Drug: ZL-1310
Sites in Detroit +11 more locations
Sponsor: Zai Lab (Shanghai) Co., Ltd.
Sex: All·Age: 18+
Code: NCT06885281·Phase 1, Phase 2·Recruiting·Listed Mar 2025
A First-in-human Study of PARP1 Selective Inhibitor, IMP1734, in Participants With Advanced Solid Tumors
for Advanced Solid Tumor
Sites in Detroit, Ann Arbor +12 more locations
Sponsor: Eikon Therapeutics
Sex: All·Age: 18 - 89
Code: NCT06253130·Phase 1, Phase 2·Recruiting·Listed Feb 2024
Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors
for Advanced Solid Tumors
Sites in Detroit +13 more locations
Sponsor: ModernaTX, Inc.
Sex: All·Age: 12+
Code: NCT05533697·Phase 1, Phase 2·Recruiting·Listed Sep 2022
A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)
for Locally Advanced Solid Tumor
Sites in Detroit +19 more locations
Sponsor: Nuvalent Inc.
Sex: All·Age: 12+
Code: NCT05384626·Phase 1, Phase 2·Recruiting·Listed May 2022
An Open-label Dose Escalation/Expansion Trial to Evaluate the Safety and Anti-tumor Activity of TEV-56278 Alone or in Combination With Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors
for Advanced Solid Tumors
Sites in Detroit +9 more locations
Sponsor: Teva Branded Pharmaceutical Products R&D LLC
Sex: All·Age: 18+
Code: NCT06480552·Phase 1·Recruiting·Listed Jun 2024
A Study of DB-1310 in Advanced/Metastatic Solid Tumors
for Advanced Solid Tumor
Sites in Detroit +11 more locations
Sponsor: DualityBio Inc.
Sex: All·Age: 18+
Code: NCT05785741·Phase 1, Phase 2·Recruiting·Listed Mar 2023
A Study of YL201 in Patients With Advanced Solid Tumors
for Advanced Solid Tumor
Sites in Detroit, Ann Arbor +17 more locations
Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd.
Sex: All·Age: 18+
Code: NCT05434234·Phase 1, Phase 2·Recruiting·Listed Jun 2022
Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer
for Breast Cancer
Sites in Detroit +14 more locations
Sponsor: Incyclix Bio
Sex: All·Age: 18+
Code: NCT05735080·Phase 1, Phase 2·Recruiting·Listed Feb 2023
A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors
for Advanced Solid Tumors With KRAS G12C Mutations
Drug: FMC-376
Sites in Detroit +11 more locations
Sponsor: Frontier Medicines Corporation
Sex: All·Age: 18+
Code: NCT06244771·Phase 1, Phase 2·Recruiting·Listed Feb 2024
A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)
for Locally Advanced Solid Tumor
Sites in Detroit +16 more locations
Sponsor: Nuvalent Inc.
Sex: All·Age: 18+
Code: NCT06521554·Phase 1·Recruiting·Listed Jul 2024
A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs
for Lung Cancer, Non-small Cell
Sites in Detroit +9 more locations
Sponsor: Krystal Biotech, Inc.
Sex: All·Age: 18+
Code: NCT06228326·Phase 1, Phase 2·Recruiting·Listed Jan 2024
A First-in-Human Study of YL217 in Patients With Advanced Solid Tumors
for Advanced Solid Tumor
Sites in Detroit +12 more locations
Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd.
Sex: All·Age: 18+
Code: NCT06859762·Phase 1·Recruiting·Listed Mar 2025
Study of SGR-3515 In Participants With Advanced Solid Tumors.
for Advanced Solid Tumor
Sites in Detroit, Ann Arbor +11 more locations
Sponsor: Schrödinger, Inc.
Sex: All·Age: 18+
Code: NCT06463340·Phase 1·Recruiting·Listed Jun 2024
A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)
for Locally Advanced Solid Tumor
Sites in Detroit +18 more locations
Sponsor: Nuvalent Inc.
Sex: All·Age: 12+
Code: NCT05118789·Phase 1, Phase 2·Recruiting·Listed Nov 2021
A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies
for Solid Tumor, Adult
Sites in Detroit +12 more locations
Sponsor: GV20 Therapeutics
Sex: All·Age: 18+
Code: NCT05669430·Phase 1, Phase 2·Recruiting·Listed Dec 2022
FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors
for Advanced Solid Tumor
Sites in Detroit +13 more locations
Sponsor: Fate Therapeutics
Sex: All·Age: 18+
Code: NCT06241456·Phase 1·Recruiting·Listed Feb 2024
First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer
for Advanced Solid Tumors
Sites in Detroit +8 more locations
Sponsor: Accent Therapeutics
Sex: All·Age: 18+
Code: NCT06799065·Phase 1·Recruiting·Listed Jan 2025
Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations
for Metastatic Hepatocellular Carcinoma
Sites in Detroit +8 more locations
Sponsor: Tyra Biosciences, Inc
Sex: All·Age: 18+
Code: NCT06915753·Phase 1·Recruiting·Listed Apr 2025
Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors
for Advanced Solid Tumor
Sites in Detroit +7 more locations
Sponsor: MOMA Therapeutics
Sex: All·Age: 18+
Code: NCT06974110·Phase 1·Recruiting·Listed May 2025
A First-in-human, Dose Escalation and Dose Expansion Study of SAR445877 in Adult Participants With Advanced Solid Tumors
for Solid Tumor
Sites in Detroit +8 more locations
Sponsor: Sanofi
Sex: All·Age: 18+
Code: NCT05584670·Phase 1, Phase 2·Recruiting·Listed Oct 2022
Study to Evaluate the Pharmacokinetics and Safety of Pralatrexate in Patients With Advanced Solid Tumor or Hematological Malignancy and Either Normal Hepatic Function or Mild, Moderate, or Severe Hepatic Impairment
for Advanced Solid Tumors
Sites in Detroit +2 more locations
Sponsor: Acrotech Biopharma Inc.
Sex: All·Age: 18+
Code: NCT07036133·Phase 1·Recruiting·Listed Jun 2025
Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors
for Solid Tumor, Adult
Sites in Detroit +3 more locations
Sponsor: Sairopa B.V.
Sex: All·Age: 18+
Code: NCT05856981·Phase 1·Recruiting·Listed May 2023
BP1001-A in Patients With Advanced or Recurrent Solid Tumors
for Solid Tumor, Adult
Sites in Detroit +3 more locations
Sponsor: Bio-Path Holdings, Inc.
Sex: All·Age: 18+
Code: NCT04196257·Phase 1·Recruiting·Listed Dec 2019
To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetic Profile of ABN401 in Patients With Advanced Solid Tumors Harboring c-MET Dysregulation
for Advanced Solid Tumors
Sites in Detroit +3 more locations
Sponsor: Abion Inc
Sex: All·Age: 18+
Code: NCT05541822·Phase 2·Recruiting·Listed Sep 2022
JAB-2485 Activity in Adult Patients With Advanced Solid Tumors
for Solid Tumors
Sites in Detroit +3 more locations
Sponsor: Jacobio Pharmaceuticals Co., Ltd.
Sex: All·Age: 18+
Code: NCT05490472·Phase 1, Phase 2·Recruiting·Listed Aug 2022
A Beta-only IL-2 ImmunoTherapY Study
for Advanced Solid Tumor
Sites in Detroit +4 more locations
Sponsor: Medicenna Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT05086692·Phase 1, Phase 2·Recruiting·Listed Oct 2021
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
for Acute Lymphoblastic Leukemia
Sites in Detroit, Dearborn +616 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: 40 - 75·Accepts healthy volunteers
Code: NCT05334069·Recruiting·Listed Apr 2022
Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain
for Anatomic Stage IV Breast Cancer AJCC v8
Sites in Detroit, Livonia +255 more locations
Sponsor: NRG Oncology
Sex: All·Age: 18+
Code: NCT06500455·Phase 3·Recruiting·Listed Jul 2024
Project: Every Child for Younger Patients With Cancer
for Adrenal Gland Pheochromocytoma
Sites in Detroit, Royal Oak +225 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: Up to 25
Code: NCT02402244·Recruiting·Listed Mar 2015
Top Research Study Locations in Detroit
Researchers run research studies in Detroit, MI at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Henry Ford Hospital | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Heart Failure | 132 |
| Karmanos Cancer Institute | Ovarian Cancer, Advanced Solid Tumor, Endometrial Cancer | 89 |
| Henry Ford Health System | Advanced Solid Tumor, Brain Tumor, Breast Cancer | 68 |
| Henry Ford Health | Heart Failure, Advanced Solid Tumor, Amyotrophic Lateral Sclerosis | 58 |
| Children's Hospital of Michigan | Acute Myeloid Leukemia, Down Syndrome, Malignant Solid Neoplasm | 38 |
| Henry Ford Health Saint John Hospital | Anatomic Stage II Breast Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 35 |
| Wayne State University/Karmanos Cancer Institute | Stage II Lip and Oral Cavity Cancer AJCC v8, Stage III Laryngeal Cancer AJCC v8, Stage III Lip and Oral Cavity Cancer AJCC v8 | 30 |
| Wayne State University | Asthma, Benign Prostatic Hyperplasia, Cancer Support | 20 |
| Barbara Ann Karmanos Cancer Institute | Breast Neoplasms, Colorectal Neoplasms, Esophageal Neoplasms | 14 |
| Henry Ford Cancer Institute | Metastatic Solid Tumor, Locally Advanced Solid Tumor, AML | 12 |
| John D. Dingell VA Medical Center, Detroit, MI | Obstructive Sleep Apnea, Sleep Apnea, Sleep Disordered Breathing | 12 |
| GSK Investigational Site | Neoplasms, Colonic Neoplasms, Liver Diseases, Alcoholic | 8 |
| Karmanos Cancer Center | Breast Neoplasms, Cancer Weight Loss, Chronic Lymphocytic Leukemia (CLL) | 7 |
| Henry Ford Health Hospital | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 6 |
| Tolan Park Medical Building | PTSD, Polysubstance Abuse, Adolescence | 6 |
| Detroit Medical Center | Diabetes (DM), Diabetic Ketoacidosis, Gastric Emptying | 5 |
| Henry Ford | ADHF, Atrial Fibrillation (AF), Brain Tumor - Metastatic | 5 |
| Detroit Receiving Hospital | Traumatic Brain Injury, Lumbar Spinal Stenosis, Status Epilepticus | 4 |
| Henry Ford Cancer - Detroit (Brigitte Harris Cancer Pavilion) | Advanced Colorectal Cancer (Part 1), Glioma, KRAS G12C-mutated Solid Tumors, Lung Cancer | 4 |
| Henry Ford Cancer Center | Locally Advanced Solid Tumor, Hemoglobinopathy, Metastatic Solid Tumor | 4 |
| Henry Ford Medical Center | Acute Kidney Injury, Coronary Artery Disease, Healthy | 4 |
| Henry Ford St. John Hospital | Cardiovascular Diseases, Hypertension, Vascular Diseases | 4 |
| Ascension Saint John Hospital | Anatomic Stage IV Breast Cancer AJCC v8, Elevated CA15-3 or CEA or CA27-29, Estrogen Receptor Positive | 3 |
| Ascension St. John Hospital | High-Risk Percutaneous Coronary Intervention, Pulmonary Embolism, Right Ventricular (RV) Dysfunction | 3 |
| Brigitte Harris Cancer Pavilion | Glioma, Melanoma, Thyroid Cancer | 3 |
Active & Upcoming Studies in Detroit (2026)
Recruiting trials in Detroit grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (304 active studies)
- Perioperative Cemiplimab for Resectable Non-Small Cell Lung Cancer With High PD-L1 · Phase 2 · Henry Ford Health System
- A Study of the TheraBionic P1 Device in Breast Cancer · Barbara Ann Karmanos Cancer Institute
Cardiovascular (51 active studies)
- Emergency Department-Initiated Team-Based Care for Severe Hypertension · Henry Ford Health System
- A Study to Test How Well BAY 3670549 Works and How Safe it is in Patients With Atrial Fibrillation · Phase 2 · Bayer
Neurology & pain (26 active studies)
- Behavioral Optimization to Overcome Obstructive Sleep Apnea Treatment Barriers · VA Office of Research and Development
- Central Apnea in Heart Failure: Physiological Mechanisms to Inform Treatment · Phase 4 · VA Office of Research and Development
Diabetes & metabolic (15 active studies)
- Can Mindfulness and Virtual Reality Reduce Stress in Young Adults With Type 1 Diabetes? · Wayne State University
- Effects of Peanut Consumption on Adults With Metabolic Associated Fatty Liver Disease · Henry Ford Health System
Mental health & behavior (11 active studies)
- Understanding Non-invasive Vagus Nerve Stimulation Effects in PTSD · EARLY_Phase 1 · Wayne State University
- Wayne State Warriors Marijuana Clinical Research Program: Cannabinoid Adjunct to Prolonged Exposure & Recovery · Phase 1, Phase 2 · Leslie Lundahl
HIV / STI (4 active studies)
- Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention · Gilead Sciences
- A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062) · Phase 2, Phase 3 · Merck Sharp & Dohme LLC
Vaccines (3 active studies)
- A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised · Phase 3 · Pfizer
- Predictors of Post-COVID-19 Clinical and Cognitive Consequences · VA Office of Research and Development
Eye & vision (3 active studies)
- Comparison of Goniotomy Device Outcomes in Combined Phacoemulsification-goniotomy Surgeries · Henry Ford Health System
- Community Based Treatment for (ComBaT) Glaucoma · University of Michigan
Pediatric (3 active studies)
- Optimizing Pain Treatment in Children On Mechanical Ventilation · Phase 3 · Weill Medical College of Cornell University
- Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS · Phase 2, Phase 3 · Nationwide Children's Hospital
Common conditions studied in Detroit
- Endometrial Cancer (14 active studies)
- Advanced Solid Tumor (13 active studies)
- Breast Cancer (13 active studies)
- Heart Failure (13 active studies)
- Ovarian Cancer (12 active studies)
- Multiple Myeloma (11 active studies)
Leading research sponsors in Detroit
- Henry Ford Health System
- National Cancer Institute (NCI)
- AstraZeneca
- Wayne State University
- SWOG Cancer Research Network
Frequently asked questions
How many paid clinical trials are currently recruiting in Detroit?
There are approximately 718 recruiting clinical trials in Detroit, Michigan listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Detroit pay participants?
Most recruiting trials in Detroit compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Detroit?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Detroit?
The most common conditions under active study in Detroit include Endometrial Cancer (14), Advanced Solid Tumor (13), Breast Cancer (13), Heart Failure (13), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Detroit?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Detroit on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Detroit?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Detroit?
Recruiting research sites in Detroit include Henry Ford Hospital, Karmanos Cancer Institute, Henry Ford Health System, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Detroit right now?
The largest active categories in Detroit are Cancer & tumors (304), Cardiovascular (51), Neurology & pain (26). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
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