Paid Clinical Trials in Detroit, MI
As of July 2026, 728 paid clinical trials are recruiting in Detroit, Michigan. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Detroit offers studies at sites including Henry Ford Hospital for conditions such as Endometrial Cancer, Advanced Solid Tumor, Ovarian Cancer, Breast Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Detroit
Trials by drug in Detroit
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Newly added in Detroit
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Understanding Pathways to Wellness and Recovery in Detroit - Digital Recovery Support Services
A Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation
Safety and Efficacy of Adjunct Therapies in Adults With Type 1 Diabetes: Multicenter, Registry Study
A Phase IIb Study to Evaluate AZD8965 in Participants With IPF.
Effects of Peanut Consumption on Adults With Metabolic Associated Fatty Liver Disease
678 clinical trials
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE.
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention
Phase 2 Study to Assess the Safety and Efficacy of ANG003
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer
A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS)
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
A Study of Pasritamig Versus Placebo in Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2
A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)
Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised
A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic Urothelial Cancer With Disease Progression on or After Immunotherapy
A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)
Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
A Study to Evaluate the Safety and Efficacy of BGB-16673 Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Top Research Study Locations in Detroit
Researchers run research studies in Detroit, MI at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Henry Ford Hospital | Acute Myeloid Leukemia, Melanoma, Anatomic Stage II Breast Cancer AJCC v8 | 138 |
| Karmanos Cancer Institute | Ovarian Cancer, Advanced Solid Tumor, Endometrial Cancer | 87 |
| Henry Ford Health System | Advanced Solid Tumor, Brain Tumor, Breast Cancer | 72 |
| Henry Ford Health | Heart Failure, Advanced Solid Tumor, Amyotrophic Lateral Sclerosis | 55 |
| Children's Hospital of Michigan | Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia, Down Syndrome | 40 |
| Henry Ford Health Saint John Hospital | Anatomic Stage II Breast Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 36 |
| Wayne State University/Karmanos Cancer Institute | Stage II Lip and Oral Cavity Cancer AJCC v8, Stage III Laryngeal Cancer AJCC v8, Stage III Lip and Oral Cavity Cancer AJCC v8 | 33 |
| Wayne State University | Asthma, Benign Prostatic Hyperplasia, Cancer Support | 20 |
| Barbara Ann Karmanos Cancer Institute | Breast Neoplasms, Colorectal Neoplasms, Esophageal Neoplasms | 15 |
| John D. Dingell VA Medical Center, Detroit, MI | Obstructive Sleep Apnea, Sleep Apnea, Sleep Disordered Breathing | 11 |
| Henry Ford Cancer Institute | Metastatic Solid Tumor, Locally Advanced Solid Tumor, AML | 10 |
| GSK Investigational Site | Neoplasms, Colonic Neoplasms, Liver Diseases, Alcoholic | 8 |
| Henry Ford Health Hospital | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 6 |
| Karmanos Cancer Center | Breast Neoplasms, Cancer Weight Loss, Chronic Lymphocytic Leukemia (CLL) | 6 |
| Tolan Park Medical Building | PTSD, Polysubstance Abuse, Adolescence | 6 |
| Detroit Medical Center | Diabetes (DM), Diabetic Ketoacidosis, Gastric Emptying | 5 |
| Henry Ford | ADHF, Atrial Fibrillation (AF), Brain Tumor - Metastatic | 5 |
| Henry Ford St. John Hospital | Atrial Fibrillation, Cardiovascular Diseases, Coronary Artery Disease (CAD) | 5 |
| Clinical Trial Site | Acid Cholesteryl Ester Hydrolase Deficiency, Type 2, Acid Lipase Deficiency, Advanced Breast Cancer | 4 |
| Detroit Receiving Hospital | Traumatic Brain Injury, Lumbar Spinal Stenosis, Status Epilepticus | 4 |
| Henry Ford Cancer Center | Locally Advanced Solid Tumor, Hemoglobinopathy, Metastatic Solid Tumor | 4 |
| Ascension Saint John Hospital | Anatomic Stage IV Breast Cancer AJCC v8, Elevated CA15-3 or CEA or CA27-29, Estrogen Receptor Positive | 3 |
| Ascension St. John Hospital | High-Risk Percutaneous Coronary Intervention, Pulmonary Embolism, Right Ventricular (RV) Dysfunction | 3 |
| Brigitte Harris Cancer Pavilion | Glioma, Melanoma, Thyroid Cancer | 3 |
| Childrens Hospital of Michigan | Crohn's Disease, Generalised Lipodystrophy, Partial Lipodystrophy | 3 |
Active & Upcoming Studies in Detroit (2026)
Recruiting trials in Detroit grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (313 active studies)
- Perioperative Cemiplimab for Resectable Non-Small Cell Lung Cancer With High PD-L1 · Phase 2 · Henry Ford Health System
- A Study of the TheraBionic P1 Device in Breast Cancer · Barbara Ann Karmanos Cancer Institute
Cardiovascular (49 active studies)
- A Study of LY3971297 in Participants With Heart Failure · Phase 1 · Eli Lilly and Company
- A Study to Test How Well BAY 3670549 Works and How Safe it is in Patients With Atrial Fibrillation · Phase 2 · Bayer
Neurology & pain (29 active studies)
- Behavioral Optimization to Overcome Obstructive Sleep Apnea Treatment Barriers · VA Office of Research and Development
- Central Apnea in Heart Failure: Physiological Mechanisms to Inform Treatment · Phase 4 · VA Office of Research and Development
Diabetes & metabolic (14 active studies)
- Effects of Peanut Consumption on Adults With Metabolic Associated Fatty Liver Disease · Henry Ford Health System
- Safety Evaluation of MODI, an Insulin Titration Algorithm, in Adults With Diabetes · DreaMed Diabetes
Mental health & behavior (11 active studies)
- Understanding Non-invasive Vagus Nerve Stimulation Effects in PTSD · EARLY_Phase 1 · Wayne State University
- Peer-Delivered Behavioral Activation in a CCBHC · Wayne State University
HIV / STI (4 active studies)
- Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention · Gilead Sciences
- A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062) · Phase 2, Phase 3 · Merck Sharp & Dohme LLC
Pediatric (4 active studies)
- Optimizing Pain Treatment in Children On Mechanical Ventilation · Phase 3 · Weill Medical College of Cornell University
- A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM). · Phase 2, Phase 3 · Cytokinetics
Vaccines (3 active studies)
- A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised · Phase 3 · Pfizer
- Predictors of Post-COVID-19 Clinical and Cognitive Consequences · VA Office of Research and Development
Eye & vision (3 active studies)
- Comparison of Goniotomy Device Outcomes in Combined Phacoemulsification-goniotomy Surgeries · Henry Ford Health System
- Community Based Treatment for (ComBaT) Glaucoma · University of Michigan
Common conditions studied in Detroit
- Endometrial Cancer (15 active studies)
- Advanced Solid Tumor (14 active studies)
- Ovarian Cancer (14 active studies)
- Breast Cancer (13 active studies)
- Acute Myeloid Leukemia (12 active studies)
- Heart Failure (12 active studies)
Leading research sponsors in Detroit
- Henry Ford Health System
- National Cancer Institute (NCI)
- AstraZeneca
- Wayne State University
- NRG Oncology
Frequently asked questions
How many paid clinical trials are currently recruiting in Detroit?
There are approximately 728 recruiting clinical trials in Detroit, Michigan listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Detroit pay participants?
Most recruiting trials in Detroit compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Detroit?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Detroit?
The most common conditions under active study in Detroit include Endometrial Cancer (15), Advanced Solid Tumor (14), Ovarian Cancer (14), Breast Cancer (13), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Detroit?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Detroit on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Detroit?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Detroit?
Recruiting research sites in Detroit include Henry Ford Hospital, Karmanos Cancer Institute, Henry Ford Health System, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Detroit right now?
The largest active categories in Detroit are Cancer & tumors (313), Cardiovascular (49), Neurology & pain (29). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.