As of October 2026, 6 paid clinical trials are testing Methotrexate in Greenville, South Carolina. Trials typically compensate participants for time, travel, and study visits, and many also provide study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Researchers run research studies in Greenville, SC at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Prisma Health Cancer Institute - Faris | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Lung Non-Small Cell Carcinoma | 48 |
| Prisma Health Cancer Institute - Eastside | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Lung Non-Small Cell Carcinoma | 47 |
| Prisma Health Cancer Institute - Butternut | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Lung Non-Small Cell Carcinoma | 42 |
| BI-LO Charities Children's Cancer Center | B Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Down Syndrome | 28 |
| Prisma Health | End Stage Renal Disease, Intracranial Aneurysm, AML | 25 |
| Prisma Health Greenville Memorial Hospital | Malignant Solid Neoplasm, Acute Decompensated Heart Failure, Acute Lymphoblastic Leukemia | 22 |
| Saint Francis Cancer Center | Lung Non-Small Cell Carcinoma, Stage IVA Prostate Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8 | 15 |
| Saint Francis Hospital | Lung Non-Small Cell Carcinoma, Advanced Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8 | 14 |
| Prisma Health - Upstate | Acute Myocardial Infarction, Acute Stroke, Amputation | 10 |
| Prisma Health Cancer Institute | Advanced Melanoma, Advanced Solid Tumor, Amyloid Cardiomyopathy | 9 |
| Tribe Clinical Research, LLC | Obesity, Overweight, Atopic Dermatitis | 7 |
| Prisma Health-Upstate | AAA - Abdominal Aortic Aneurysm, AV Block, Advanced Solid Tumor | 5 |
| Prisma Health Upstate | Acute Limb Ischemia, Chronic Graft-versus-host-disease, Diastolic Heart Failure | 5 |
| GSK Investigational Site | Pulmonary Disease, Chronic Obstructive, Chickenpox, Nasal Polyps | 4 |
| PCPMG Clinical Research Unit, LLC | Chronic Pain, Chronic Leg Pain, Chronic Low-back Pain | 4 |
| Premier Neurology | Multiple Sclerosis (MS) Primary Progressive, Relapsing Multiple Sclerosis, Secondary Progressive Multiple Sclerosis | 4 |
| Greenwood Genetic Center - Greenville | Cerebroside Lipidosis Syndrome, Fabry Disease, Gaucher Disease | 4 |
| Gastroenterology Associates - Patewood | Obesity or Overweight, Crohn's Disease, Ulcerative Colitis | 3 |
| Prisma Health- Upstate | Articular Fractures, Chronic Renal Disease, End Stage Renal Disease (ESRD) | 3 |
| Clinical Study Site | Metastatic Colorectal Cancer (CRC), Non-Small Cell Lung Cancer | 2 |
| Greenville Memorial Hospital | Alcohol Use Disorder, Symptomatic Hypertrophic Cardiomyopathy (HCM) | 2 |
| Palmetto Clinical Trial Services, LLC | Actinic Keratosis | 2 |
| Retina Consultants of Carolina | Age-related Macular Degeneration (AMD), Choroidal Melanoma, Geographic Atrophy (GA) | 2 |
| St Francis Cancer Center | Breast Neoplasms, Carcinoma, Non-Small-Cell Lung | 2 |
| Steadman Hawkins Clinic of the Carolinas | Ankylosing Spondylitis, Fracture, Infections | 2 |
Recruiting trials in Greenville grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
There are approximately 271 recruiting clinical trials in Greenville, South Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Greenville compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Greenville include Acute Myeloid Leukemia (9), Obesity (7), Breast Cancer (6), Malignant Solid Neoplasm (6), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Greenville on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Greenville include Prisma Health Cancer Institute - Faris, Prisma Health Cancer Institute - Eastside, Prisma Health Cancer Institute - Butternut, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Greenville are Cancer & tumors (102), Diabetes & metabolic (18), Neurology & pain (16). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.