Clinical Trials at Mayo Clinic
As of August 2026, 71 paid clinical trials are recruiting at Mayo Clinic, located at 4500 SAN PABLO RD S, JACKSONVILLE, FL 32224-1865, phone (904) 953-7330 in Jacksonville, Florida. Active studies at this site cover conditions such as Obesity, Malignant Solid Neoplasm and Breast Cancer. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Jacksonville
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
72 clinical trials at Mayo Clinic
·Clear filters·Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis
Trial of Nadofaragene Firadenovec vs. Observation in Participants With Intermediate Risk Non-Muscle Invasive Bladder Cancer
FOG-001 in Locally Advanced or Metastatic Solid Tumors
Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)
Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)
Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer
Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion
CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)
Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALS
Gene Therapy for HER-Positive Cancer (SENTRY-HER2)
RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus
A Study of 177Lu-FAP-2286 in Advanced Solid Tumors
A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease
A Study of SYNC-T Therapy SV-102 in Participants With Metastatic Castration-Resistant Prostate Cancer
A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers
MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma
A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
Targeted Alpha-Particle Therapy for Advanced Somatostatin Receptor Type 2 (SSTR2) Positive Tumors
Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3
A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
Exactech Shoulder Post Market Clinical Follow-up Study
DCSZ11 as a Monotherapy and in Combination in Patients With Advanced or Metastatic Solid Tumors
Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration
A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
INdependence Through Endovascular Neuroprosthetic Technology (INTENT): an Early Feasibility Study
A Study of Lirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or Rearrangement
Accuracy of a Cuffless Photoplethysmography (PPG) Chest-Patch Monitor for 24-hour Ambulatory Blood Pressure Monitoring (ABPM)
A Study of JNJ-90301900 in Combination With Chemoradiation Therapy in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma
Randomized Study on Transoral Outlet Reduction and Lifestyle Changes for Weight Regain After Gastric Bypass
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-011 in Patients With Advanced Solid Tumor
Low-grade UTUC Treated With Nadofaragene Firadenovec Administered to Renal Pelvis
CraniSeal Post Approval Study
Study of SX-682 Alone and in Combination With Oral or Intravenous Decitabine in Subjects With Myelodysplastic Syndrome
Common conditions studied in Jacksonville
- Obesity (20 active studies)
- Malignant Solid Neoplasm (19 active studies)
- Breast Cancer (16 active studies)
- Heart Failure (16 active studies)
- Overweight (14 active studies)
- Prostate Cancer (13 active studies)
Leading research sponsors in Jacksonville
- Mayo Clinic
- AstraZeneca
- University of Florida
- Children's Oncology Group
- Eli Lilly and Company
Frequently asked questions
How many paid clinical trials are currently recruiting in Jacksonville?
There are approximately 925 recruiting clinical trials in Jacksonville, Florida listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Jacksonville pay participants?
Most recruiting trials in Jacksonville compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Jacksonville?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Jacksonville?
The most common conditions under active study in Jacksonville include Obesity (20), Malignant Solid Neoplasm (19), Breast Cancer (16), Heart Failure (16), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Jacksonville?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Jacksonville on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Jacksonville?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Jacksonville?
Recruiting research sites in Jacksonville include Mayo Clinic in Florida, Mayo Clinic, Mayo Clinic Florida, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Jacksonville right now?
The largest active categories in Jacksonville are Cancer & tumors (302), Cardiovascular (68), Neurology & pain (53). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of Mayo Clinic?
Mayo Clinic is located at 4500 SAN PABLO RD S, JACKSONVILLE, FL 32224-1865. Use the Google Maps link in the intro above to get directions.
How do I contact Mayo Clinic?
You can reach Mayo Clinic by phone at (904) 953-7330. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.