Community Enhanced Virtual Informed Consent
for Hematopoietic and Lymphatic System Neoplasm
1 location in Jacksonville
Sponsor: Mayo Clinic
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07805083·Recruiting·Listed Sep 4, 2026
Solid tumor Clinical Trials in Jacksonville, FL
As of September 2026, 46 paid clinical trials are recruiting for Solid tumor in Jacksonville, Florida. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Jacksonville
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
47 clinical trials for Solid tumor
·Clear filters· Email me when a new solid tumor trial opens in Jacksonville, FL.
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
for Solid Tumors
Drug: INCB161734
Sites in Jacksonville, St. Petersburg +67 more locations
Sponsor: Incyte Corporation
Sex: All·Age: 18+
Code: NCT07522073·Phase 3·Recruiting·Listed Apr 2026
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
for Renal Cell Carcinoma (RCC)
Sites in Jacksonville, Gainesville +42 more locations
Sponsor: Exelixis
Sex: All·Age: 18+
Code: NCT05176483·Phase 1·Recruiting·Listed Jan 2022
Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion
for Mesothelioma
Drug: MRTX1719
Sites in Jacksonville, Orlando +20 more locations
Sponsor: Bristol-Myers Squibb
Sex: All·Age: 18+
Code: NCT05245500·Phase 1·Recruiting·Listed Feb 2022
FOG-001 in Locally Advanced or Metastatic Solid Tumors
for Cancer
Sites in Jacksonville +29 more locations
Sponsor: Parabilis Medicines, Inc.
Sex: All·Age: 18+
Code: NCT05919264·Phase 1, Phase 2·Recruiting·Listed Jun 2023
Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
for Solid Tumor, Adult
Sites in Jacksonville, Tampa +11 more locations
Sponsor: A2 Biotherapeutics Inc.
Sex: All·Age: 18+
Code: NCT04981119·Recruiting·Listed Jul 2021
Study of Lunresertib Alone or in Combination With RP-3500 or Debio 0123 in Patients With Advanced Solid Tumors
for Advanced Solid Tumor
Sites in Jacksonville +13 more locations
Sponsor: Debiopharm International SA
Sex: All·Age: 12+
Code: NCT04855656·Phase 1·Recruiting·Listed Apr 2021
A Study of 177Lu-FAP-2286 in Advanced Solid Tumors
for Solid Tumor
Sites in Jacksonville, Miami +18 more locations
Sponsor: Novartis Pharmaceuticals
Sex: All·Age: 18+
Code: NCT04939610·Phase 1, Phase 2·Recruiting·Listed Jun 2021
A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers
for Advanced Solid Tumor
Drug: NXP900
Sites in Jacksonville +12 more locations
Sponsor: Nuvectis Pharma, Inc.
Sex: All·Age: 18+
Code: NCT05873686·Phase 1·Recruiting·Listed May 2023
A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
for Solid Tumor, Adult
Sites in Jacksonville, Tampa +10 more locations
Sponsor: A2 Biotherapeutics Inc.
Sex: All·Age: 18+
Code: NCT06051695·Phase 1, Phase 2·Recruiting·Listed Sep 2023
Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss
for Non Small Cell Lung Cancer
Sites in Jacksonville +14 more locations
Sponsor: Tango Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT06810544·Phase 1, Phase 2·Recruiting·Listed Feb 2025
A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors
for Advanced Solid Tumor
Sites in Jacksonville, Orlando +11 more locations
Sponsor: Exelixis
Sex: All·Age: 18+
Code: NCT05932862·Phase 1·Recruiting·Listed Jul 2023
Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration
for Solid Tumors
Sites in Jacksonville, Tampa +15 more locations
Sponsor: ORIC Pharmaceuticals
Sex: All·Age: 18+
Code: NCT05315700·Phase 1, Phase 2·Recruiting·Listed Apr 2022
A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
for Solid Tumor, Adult
Sites in Jacksonville, Tampa +8 more locations
Sponsor: A2 Biotherapeutics Inc.
Sex: All·Age: 18+
Code: NCT06682793·Phase 1, Phase 2·Recruiting·Listed Nov 2024
Study of RYZ401 in Subjects With Solid Tumors Expressing SSTRs.
for GEP-NET
Sites in Jacksonville +11 more locations
Sponsor: RayzeBio, Inc.
Sex: All·Age: 18+
Code: NCT07165132·Phase 1·Recruiting·Listed Sep 2025
A Study of KK2269 in Adult Participants With Solid Tumors
for Advanced Solid Tumor
Sites in Jacksonville +6 more locations
Sponsor: Kyowa Kirin Co., Ltd.
Sex: All·Age: 18+
Code: NCT06266299·Phase 1·Recruiting·Listed Feb 2024
An Extension Study for Patients Previously Enrolled in Studies With Pelabresib
for Hematologic Malignancy
Drug: Pelabresib
Sites in Jacksonville +5 more locations
Sponsor: Novartis Pharmaceuticals
Sex: All·Age: 18+
Code: NCT06401356·Phase 3·Recruiting·Listed May 2024
A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid Tumors
for Advanced Solid Tumors
Sites in Jacksonville, Tampa +6 more locations
Sponsor: Vividion Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT05954312·Phase 1·Recruiting·Listed Jul 2023
Study of IBI3020 Treatment in Participants With Late-Stage Solid Tumors
for Solid Tumors
Sites in Jacksonville +5 more locations
Sponsor: Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD.
Sex: All·Age: 18 - 75
Code: NCT06963281·Phase 1·Recruiting·Listed May 2025
A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)
for Advanced Solid Tumor
Sites in Jacksonville +4 more locations
Sponsor: GI Innovation, Inc.
Sex: All·Age: 18+
Code: NCT05824975·Phase 1, Phase 2·Recruiting·Listed Apr 2023
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
for Advanced Malignant Solid Neoplasm
Sites in Jacksonville, Gainesville +427 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: All ages
Code: NCT05564377·Phase 2·Recruiting·Listed Oct 2022
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer
for Hematopoietic and Lymphatic System Neoplasm
Sites in Jacksonville, Gainesville +189 more locations
Sponsor: Children's Oncology Group
Sex: Female·Age: Up to 39
Code: NCT06513962·Phase 3·Recruiting·Listed Jul 2024
Project: Every Child for Younger Patients With Cancer
for Adrenal Gland Pheochromocytoma
Sites in Jacksonville, Gainesville +225 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: Up to 25
Code: NCT02402244·Recruiting·Listed Mar 2015
The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
for Amyloidosis
1 location in Jacksonville
Sponsor: Mayo Clinic
Sex: All·Age: 18+
Code: NCT07285044·Phase 2·Recruiting·Listed Dec 2025
Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Platinum Resistant Ovarian Cancer
for Metastatic Malignant Solid Neoplasm
Drug: Olaparib
Sites in Jacksonville, Deerfield Beach +10 more locations
Sponsor: National Cancer Institute (NCI)
Sex: All·Age: 18+
Code: NCT04585958·Phase 1·Recruiting·Listed Oct 2020
A Virtual Community Health Educator for Increasing Clinical Trial Referrals Among Cancer Patients and Their Caregivers
for Hematopoietic and Lymphatic System Neoplasm
1 location in Jacksonville
Sponsor: Mayo Clinic
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07126496·Recruiting·Listed Aug 2025
Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors
for Anatomic Stage III Breast Cancer AJCC v8
1 location in Jacksonville
Sponsor: Mayo Clinic
Sex: All·Age: 16+
Code: NCT05269381·Phase 1, Phase 2·Recruiting·Listed Mar 2022
Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors
for Malignant Solid Neoplasm
Sites in Jacksonville +3 more locations
Sponsor: Mayo Clinic
Sex: All·Age: 18+
Code: NCT03750227·Phase 3·Recruiting·Listed Nov 2018
Biomarkers to Predict Cancer Therapy-related Cardiotoxicity
for Hematopoietic and Lymphatic System Neoplasm
Sites in Jacksonville, Tampa +1 more location
Sponsor: Mayo Clinic
Sex: All·Age: 18+
Code: NCT06353191·Recruiting·Listed Apr 2024
Collection of Research Data and Samples From Patients Treated With Immunotherapy to Study Its Side Effects
for Hematopoietic and Lymphoid Cell Neoplasm
Sites in Jacksonville, Fort Lauderdale +392 more locations
Sponsor: Alliance for Clinical Trials in Oncology
Sex: All·Age: All ages
Code: NCT04242095·Recruiting·Listed Jan 2020
Evaluation of a Novel Auto Segmentation Algorithm for Normal Structure Delineation in Radiation Treatment Planning
for Malignant Solid Neoplasm
Sites in Jacksonville +6 more locations
Sponsor: Mayo Clinic
Sex: All·Age: All ages·Accepts healthy volunteers
Code: NCT06200116·Recruiting·Listed Jan 2024
Using Induced-Pluripotent Stem Cells to Model Cancer Therapy-Related Adverse Events
for Hematopoietic and Lymphatic System Neoplasm
1 location in Jacksonville
Sponsor: Mayo Clinic
Sex: All·Age: 18+
Code: NCT06640010·Recruiting·Listed Oct 2024
Ex Vivo Expansion (ACT-X)
for Solid Tumor
1 location in Jacksonville
Sponsor: Mayo Clinic
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07137312·Recruiting·Listed Aug 2025
Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program
for Advanced Esophageal Squamous Cell Carcinoma
Drug: Nivolumab
1 location in Jacksonville
Sponsor: Mayo Clinic
Sex: All·Age: 18+
Code: NCT06265285·Phase 2·Recruiting·Listed Feb 2024
Intravital Microscopy in Human Solid Tumors
for Solid Tumor, Adult
1 location in Jacksonville
Sponsor: Mayo Clinic
Sex: All·Age: 18+
Code: NCT03823144·Recruiting·Listed Jan 2019
A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study
for Hematopoietic and Lymphatic System Neoplasm
Sites in Jacksonville, Orlando +74 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: 15 - 20
Code: NCT06410209·Phase 2·Recruiting·Listed May 2024
Virtual Reality Intervention to Improve Psychological Symptom Burden for Cancer Patients Undergoing Treatment
for Adjustment Disorder
1 location in Jacksonville
Sponsor: Mayo Clinic
Sex: All·Age: 18 - 90
Code: NCT07221409·Recruiting·Listed Oct 2025
A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients
for Hematopoietic and Lymphoid Cell Neoplasm
Sites in Jacksonville, Miami +26 more locations
Sponsor: Children's Oncology Group
Sex: All·Age: 2 - 18
Code: NCT05711667·Phase 3·Recruiting·Listed Feb 2023
At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer
for Advanced Anal Carcinoma
Sites in Jacksonville +1 more location
Sponsor: Mayo Clinic
Sex: All·Age: 18+
Code: NCT05969860·Phase 2·Recruiting·Listed Aug 2023
SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial
for Metastatic Malignant Neoplasm in the Brain
Sites in Jacksonville +6 more locations
Sponsor: Mayo Clinic
Sex: All·Age: 18+
Code: NCT05222620·Phase 2·Recruiting·Listed Feb 2022
INTERogating Cancer for Etiology, Prevention and Therapy Navigation
for Cancer
Sites in Jacksonville +2 more locations
Sponsor: Mayo Clinic
Sex: All·Age: 18+
Code: NCT06008392·Recruiting·Listed Aug 2023
Top Research Study Locations in Jacksonville
Researchers run research studies in Jacksonville, FL at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Mayo Clinic in Florida | Malignant Solid Neoplasm, Hematopoietic and Lymphatic System Neoplasm, Anatomic Stage II Breast Cancer AJCC v8 | 167 |
| Mayo Clinic | Amyotrophic Lateral Sclerosis, Colorectal Cancer, Breast Cancer | 85 |
| Mayo Clinic Florida | Amyotrophic Lateral Sclerosis, Advanced Melanoma, CRC | 77 |
| Mayo Clinic Jacksonville | Non Small Cell Lung Cancer, Amyotrophic Lateral Sclerosis (ALS), Chronic Lymphocytic Leukemia | 47 |
| Nemours Children's Clinic-Jacksonville | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 32 |
| Jacksonville Center for Clinical Research | Obesity, Heart Failure, Overweight | 23 |
| Baptist MD Anderson Cancer Center | Breast Cancer, Advanced Melanoma, Anatomic Stage II Breast Cancer AJCC v8 | 19 |
| Cancer Specialists of North Florida | Breast Cancer, Carcinoma, Non-Small-Cell Lung, Acinar Cell Carcinoma | 13 |
| University of Florida | Coronary Artery Disease, Allergies, Arthropathy of Hip | 12 |
| Mayo Clinic - Jacksonville | Adenoid Cystic Carcinoma, Amyloid Cardiomyopathy, Amyloidosis | 10 |
| Brooks Rehabilitation | Spinal Cord Injuries, Spinal Cord Injury, Stroke | 9 |
| Mayo Clinic - Florida | Epilepsy, Epilepsy (Treatment Refractory), Astrocytoma, Grade IV | 9 |
| University of Florida Jacksonville | Coronary Artery Disease, AV Block, Acute Stroke | 8 |
| Ascension St. Vincent's | Atrial Fibrillation, Brain Tumor, Brain Tumor - Metastatic | 7 |
| Baptist Medical Center Jacksonville | Intracranial Aneurysm, Chronic Subdural Hematoma, Intracranial Atherosclerotic Stenosis (ICAS) | 7 |
| Nemours Children's Health | Type 1 Diabetes, Asthma (Diagnosis), Autosomal Dominant Hypocalcemia Type 1 (ADH1) | 7 |
| UF Health Jacksonville | Atrial Fibrillation, Diabetes Mellitus, Type 2, Heart Failure | 7 |
| Baptist Health Research Institute | Acute Ischemic Stroke, Alzheimer Disease, Aneurysm, Intracranial | 6 |
| Mayo Clinic Cancer Center | Acute Myeloid Leukemia, B-Cell Acute Lymphoblastic Leukaemia, CRC | 6 |
| Clinical Neuroscience Solutions, LLC | Bipolar Depression, Bipolar Disorder, Bipolar I Disorder | 5 |
| First Coast Cardiovascular Institute | Heart Failure, Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia | 5 |
| GSK Investigational Site | Non-alcoholic Fatty Liver Disease, Gastrointestinal Neoplasms, Irritable Bowel Syndrome | 5 |
| Nemours Children's Clinic | Cystic Fibrosis, Amblyopia, Cystic Fibrosis Pulmonary Exacerbation | 5 |
| University of Florida Health Jacksonville | Acute Gout Flare, Acute Ischemic Stroke, Arthritis | 5 |
| Clinical Trial Site | ATTR Amyloidosis, Advanced Hepatocellular Carcinoma, Generalized Myasthenia Gravis | 4 |
Active & Upcoming Studies in Jacksonville (2026)
Recruiting trials in Jacksonville grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (308 active studies)
Cardiovascular (64 active studies)
Diabetes & metabolic (51 active studies)
- A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide · Phase 3 · Novo Nordisk A/S
- AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight · Phase 3 · Novo Nordisk A/S
Neurology & pain (50 active studies)
- Magnesium Supplement for Sleep Quality in Women With Poor Sleep · Jacksonville University
- Arm Elevation for Prevention of Propofol Injection Pain · Mayo Clinic
Mental health & behavior (15 active studies)
- Studying NMDA and Sigma-1 in Smoking Cessation Treatment (SUMMIT) · Phase 3 · Axsome Therapeutics, Inc.
- A Trial of the Efficacy and Safety of Fixed Doses of SEP-363856 in Adults With Generalized Anxiety Disorder · Phase 3 · Otsuka Pharmaceutical Development & Commercialization, Inc.
HIV / STI (8 active studies)
- Liver Transplantation From Donors With HIV: Impact on Opportunistic Infections, Cancer, and Long-Term Outcomes (Expanding HOPE Liver) · Johns Hopkins University
- Assessing Performance of a Hepatitis C Emergency Department (HepC-EnD) Screening Tool: IT Integration Process for Electronic Health Record System · University of Florida
Eye & vision (7 active studies)
- Ixoberogene Soroparvovec (Ixo-vec) Contralateral Dosing Study in Participants With Neovascular Age-related Macular Degeneration · Phase 2 · Adverum Biotechnologies, Inc.
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
Pediatric (7 active studies)
- Effects of Glucagon-like Peptide-1 (GLP-1) Agonist in Neuro-reproductive Function in Obese Adolescent Females With Polycystic Ovary Syndrome (PCOS) · Nemours Children's Clinic
- CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D) · Phase 1, Phase 2 · COUR Pharmaceutical Development Company, Inc.
Vaccines (2 active studies)
Common conditions studied in Jacksonville
- Malignant Solid Neoplasm (20 active studies)
- Obesity (19 active studies)
- Breast Cancer (18 active studies)
- Heart Failure (16 active studies)
- Overweight (14 active studies)
- Prostate Cancer (13 active studies)
Leading research sponsors in Jacksonville
- Mayo Clinic
- AstraZeneca
- University of Florida
- National Cancer Institute (NCI)
- Children's Oncology Group
Frequently asked questions
How many paid clinical trials are currently recruiting in Jacksonville?
There are approximately 933 recruiting clinical trials in Jacksonville, Florida listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Jacksonville pay participants?
Most recruiting trials in Jacksonville compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Jacksonville?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Jacksonville?
The most common conditions under active study in Jacksonville include Malignant Solid Neoplasm (20), Obesity (19), Breast Cancer (18), Heart Failure (16), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Jacksonville?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Jacksonville on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Jacksonville?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Jacksonville?
Recruiting research sites in Jacksonville include Mayo Clinic in Florida, Mayo Clinic, Mayo Clinic Florida, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Jacksonville right now?
The largest active categories in Jacksonville are Cancer & tumors (308), Cardiovascular (64), Diabetes & metabolic (51). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
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