Solid tumor Clinical Trials in Jacksonville, FL
As of July 2026, 52 paid clinical trials are recruiting for Solid tumor in Jacksonville, Florida. Recruiting Solid tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Related specialties in Jacksonville
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52 clinical trials for Solid tumor
·Clear filters·↓ Download CSVPhase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion
FOG-001 in Locally Advanced or Metastatic Solid Tumors
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss
A Study of 177Lu-FAP-2286 in Advanced Solid Tumors
A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers
Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration
A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
Study of Lunresertib Alone or in Combination With RP-3500 or Debio 0123 in Patients With Advanced Solid Tumors
A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid Tumors
A Study of KK2269 in Adult Participants With Solid Tumors
Evaluate the Safety and Clinical Activity of HH2853
A Phase 1, First in Human Study of TORL-4-500 in Patients With Advanced Cancer
An Extension Study for Patients Previously Enrolled in Studies With Pelabresib
Study of IBI3020 Treatment in Participants With Late-Stage Solid Tumors
A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer
Project: Every Child for Younger Patients With Cancer
A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study
A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients
Ex Vivo Expansion (ACT-X)
The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
MTI-301 for the Treatment of Metastatic or Unresectable and Refractory Solid Cancers
Virtual Reality Intervention to Improve Psychological Symptom Burden for Cancer Patients Undergoing Treatment
A Virtual Community Health Educator for Increasing Clinical Trial Referrals Among Cancer Patients and Their Caregivers
Using Induced-Pluripotent Stem Cells to Model Cancer Therapy-Related Adverse Events
Evaluation of a Novel Auto Segmentation Algorithm for Normal Structure Delineation in Radiation Treatment Planning
Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program
Fasting Mimicking Diet for Reducing Immune Related Adverse Events for Cancer Patients on Immune Checkpoint Inhibitors, FMD-ICI Trial
Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform
A Collaborative Intervention for Improving Cancer Pain Management in Cancer Survivors
INTERogating Cancer for Etiology, Prevention and Therapy Navigation
At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer
Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors
Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Platinum Resistant Ovarian Cancer
About research studies in Jacksonville
Jacksonville has approximately 974 recruiting research studies across a wide range of therapeutic areas. Florida hosts major research centers including Mayo Clinic Jacksonville, Moffitt Cancer Center, University of Miami Health System, and Nicklaus Children's Hospital, with strong programs in oncology and cardiovascular research.
Top Research Study Locations in Jacksonville
Researchers run research studies in Jacksonville, FL at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Mayo Clinic in Florida | Malignant Solid Neoplasm, Hematopoietic and Lymphatic System Neoplasm, Anatomic Stage II Breast Cancer AJCC v8 | 186 |
| Mayo Clinic | Amyotrophic Lateral Sclerosis, Colorectal Cancer, Advanced Solid Tumor | 84 |
| Mayo Clinic Florida | Amyotrophic Lateral Sclerosis, Advanced Melanoma, Healthy | 78 |
| Mayo Clinic Jacksonville | Amyotrophic Lateral Sclerosis (ALS), Non Small Cell Lung Cancer, Prostate Cancer | 48 |
| Nemours Children's Clinic-Jacksonville | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 32 |
| Baptist MD Anderson Cancer Center | Breast Cancer, Advanced Melanoma, Anatomic Stage II Breast Cancer AJCC v8 | 21 |
| Jacksonville Center for Clinical Research | Heart Failure, Obesity, Cardiovascular Disease | 21 |
| University of Florida | Coronary Artery Disease, Age-related Cognitive Decline, Allergies | 14 |
| Cancer Specialists of North Florida | Carcinoma, Non-Small-Cell Lung, Non-Small Cell Lung Cancer, Acinar Cell Carcinoma | 13 |
| Mayo Clinic - Jacksonville | Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL), Adenoid Cystic Carcinoma | 12 |
| Brooks Rehabilitation | Spinal Cord Injuries, Spinal Cord Injury, Stroke | 9 |
| Mayo Clinic - Florida | Epilepsy, Epilepsy (Treatment Refractory), Astrocytoma, Grade IV | 9 |
| Nemours Children's Health | Asthma (Diagnosis), Autosomal Dominant Hypocalcemia Type 1 (ADH1), Child | 8 |
| University of Florida Jacksonville | Coronary Artery Disease, AV Block, Acute Stroke | 8 |
| Ascension St. Vincent's | Atrial Fibrillation, Brain Tumor, Brain Tumor - Metastatic | 7 |
| Baptist Health Research Institute | Acute Ischemic Stroke, Alzheimer Disease, Aneurysm, Intracranial | 7 |
| Clinical Neuroscience Solutions, Inc. | Bipolar Depression, Bipolar Disorder, Bipolar I Disorder | 7 |
| GSK Investigational Site | Non-alcoholic Fatty Liver Disease, Breast Neoplasms, Gastrointestinal Neoplasms | 7 |
| Mayo Clinic Cancer Center | Acute Myeloid Leukemia, B-Cell Acute Lymphoblastic Leukaemia, CRC | 7 |
| UF Health Jacksonville | Atrial Fibrillation, Autonomic State, Diabetes Mellitus, Type 2 | 7 |
| Baptist Medical Center Jacksonville | Intracranial Aneurysm, Chronic Subdural Hematoma, Intracranial Atherosclerotic Stenosis (ICAS) | 6 |
| Nemours Children's Clinic | Cystic Fibrosis, Amblyopia, Cystic Fibrosis Pulmonary Exacerbation | 6 |
| University of Florida Health Jacksonville | Acute Gout Flare, Acute Ischemic Stroke, Arthritis | 6 |
| Clinical Trial Site | ATTR Amyloidosis, Advanced Hepatocellular Carcinoma, Cerebral Amyloid Angiopathy | 5 |
| First Coast Cardiovascular Institute | Chronic Limb-Threatening Ischemia, Peripheral Arterial Disease, Heart Failure | 5 |
Active & Upcoming Studies in Jacksonville (2026)
Recruiting trials in Jacksonville grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (324 active studies)
Cardiovascular (68 active studies)
Neurology & pain (56 active studies)
- Erector Spinae Plane Block Versus Trigger Point Injection for Chronic Thoracic Myofascial Pain · Phase 4 · Mayo Clinic
- Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up · Epiminder America, Inc.
Diabetes & metabolic (45 active studies)
- A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide · Phase 3 · Novo Nordisk A/S
- Safety and Efficacy of NA-931 and Tirzepatide in Adults Who Are Overweight or Obese · Phase 2 · Biomed Industries, Inc.
Mental health & behavior (16 active studies)
- A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD) · Phase 2 · Tonix Pharmaceuticals, Inc.
- Subanesthetic Ketamine Infusions for Depressive Symptoms in Intensive Care Unit Patients · Phase 2 · Hospital Italiano de Buenos Aires
HIV / STI (9 active studies)
- Liver Transplantation From Donors With HIV: Impact on Opportunistic Infections, Cancer, and Long-Term Outcomes (Expanding HOPE Liver) · Johns Hopkins University
- Assessing Performance of a Hepatitis C Emergency Department (HepC-EnD) Screening Tool: IT Integration Process for Electronic Health Record System · University of Florida
Pediatric (7 active studies)
Eye & vision (5 active studies)
- Ixoberogene Soroparvovec (Ixo-vec) Contralateral Dosing Study in Participants With Neovascular Age-related Macular Degeneration · Phase 2 · Adverum Biotechnologies, Inc.
- Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD) · Phase 3 · AbbVie
Vaccines (3 active studies)
Common conditions studied in Jacksonville
- Malignant Solid Neoplasm (21 active studies). Recruiting Malignant Solid Neoplasm studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Breast Cancer (17 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Obesity (17 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
- Heart Failure (16 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Prostate Cancer (14 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
- Hematopoietic and Lymphatic System Neoplasm (13 active studies). Recruiting Hematopoietic and Lymphatic System Neoplasm studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Jacksonville
- Mayo Clinic
- AstraZeneca
- National Cancer Institute (NCI)
- University of Florida
- Children's Oncology Group
Local regulations and guidelines
Clinical trials in Florida are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Florida research must also comply with the Florida Information Protection Act (FIPA) and additional oversight from the Florida Department of Health.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Jacksonville. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Jacksonville
Hipa.ai aggregates every recruiting study in Jacksonville from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Jacksonville?
There are approximately 974 recruiting clinical trials in Jacksonville, Florida listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Jacksonville pay participants?
Most recruiting trials in Jacksonville compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Jacksonville?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Jacksonville?
The most common conditions under active study in Jacksonville include Malignant Solid Neoplasm (21), Breast Cancer (17), Obesity (17), Heart Failure (16), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Jacksonville?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Jacksonville on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Jacksonville?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Jacksonville?
Recruiting research sites in Jacksonville include Mayo Clinic in Florida, Mayo Clinic, Mayo Clinic Florida, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Jacksonville right now?
The largest active categories in Jacksonville are Cancer & tumors (324), Cardiovascular (68), Neurology & pain (56). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.