Paid Clinical Trials in O'Fallon, MO
As of August 2026, 9 paid clinical trials are recruiting in O'Fallon, Missouri. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
O'Fallon offers studies at sites including Psychiatric Care and Research Center for conditions such as Major Depressive Disorder, Bipolar Depression, Bipolar Disorder, Bipolar I Disorder. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in O'Fallon
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8 clinical trials
A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)
Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder
Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder
A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
A Study to Evaluate the Maintenance Effect of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Top Research Study Locations in O'Fallon
Researchers run research studies in O'Fallon, MO at 5 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Psychiatric Care and Research Center | Major Depressive Disorder, Bipolar Depression, Bipolar Disorder | 4 |
| Neurocrine Clinical Site | Major Depressive Disorder | 2 |
| Progress West Hospital | Lumbar Spinal Stenosis | 1 |
| Psychiatric Care and Research | Treatment Resistant Depression | 1 |
| Psychiatric Care and Research Center (PCRC) | Major Depressive Disorder | 1 |
Active & Upcoming Studies in O'Fallon (2026)
Recruiting trials in O'Fallon grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Mental health & behavior (3 active studies)
- A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression) · Phase 3 · Xenon Pharmaceuticals Inc.
- Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder · Phase 2 · AbbVie
Common conditions studied in O'Fallon
- Major Depressive Disorder (5 active studies)
- Bipolar Depression (1 active study)
- Bipolar Disorder (1 active study)
- Bipolar I Disorder (1 active study)
- Bipolar II Disorder (1 active study)
- Generalized Anxiety Disorder (GAD) (1 active study)
Leading research sponsors in O'Fallon
- Xenon Pharmaceuticals Inc.
- Neurocrine Biosciences
- AbbVie
- Intra-Cellular Therapies, Inc.
- LivaNova
Frequently asked questions
How many paid clinical trials are currently recruiting in O'Fallon?
There are approximately 9 recruiting clinical trials in O'Fallon, Missouri listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in O'Fallon pay participants?
Most recruiting trials in O'Fallon compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in O'Fallon?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in O'Fallon?
The most common conditions under active study in O'Fallon include Major Depressive Disorder (5), Bipolar Depression (1), Bipolar Disorder (1), Bipolar I Disorder (1), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in O'Fallon?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in O'Fallon on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in O'Fallon?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in O'Fallon?
Recruiting research sites in O'Fallon include Psychiatric Care and Research Center, Neurocrine Clinical Site, Progress West Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in O'Fallon right now?
The largest active categories in O'Fallon are Mental health & behavior (3). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.