Oncology Clinical Trials in Plano, TX
As of August 2026, 9 paid clinical trials are recruiting for Oncology in Plano, Texas. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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9 clinical trials for Oncology
·Clear filters·Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
A Study of TRK-950 When Used in Combination With Ramucirumab and Paclitaxel in Patients With Gastric Cancer
The TIOB - Collection of Patients' Biospecimens for Analysis of Immunological and Molecular Biomarkers.
Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations
A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR - HN1)
Top Research Study Locations in Plano
Researchers run research studies in Plano, TX at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| The Heart Hospital Baylor Plano | Aortic Valve Stenosis, Coronary Artery Disease, Abdominal Aortic Aneurysm | 12 |
| Baylor Scott & White The Heart Hospital - Plano | ANOCA - Angina With Non-obstructive Coronary Arteries, Aneurysm of Aorta, Thoracic, Aneurysmal Disease | 8 |
| Aim Trials, LLC | Acute Migraine, Generalized Anxiety Disorder, Migraine | 7 |
| Baylor Scott & White Research Institute | Heart Failure, Aortic Arch Aneurysm, Aortic Arch Dissection | 5 |
| AIM Trials | Autism Spectrum Disorder, Bipolar Disorder, Irritability Associated With Autism Spectrum Disorder | 5 |
| Texas Oncology - DFW | Breast Cancer, Advanced Non-Small Cell Lung Cancer, Breast Neoplasms | 4 |
| Baylor Research Institute | Atrial Fibrillation, Aortic Dissection, Bleeding | 3 |
| Baylor Scott & White Plano | Carotid Artery Calcification, Carotid Artery Diseases, Aortic Stenosis | 3 |
| Baylor Scott and White | AAA - Abdominal Aortic Aneurysm, Aortic Aneurysm, Aortic Dissection | 3 |
| Baylor Scott and White - The Heart Hospital Baylor Plano | Coronary Arterial Disease (CAD), Moderate Aortic Valve Stenosis, Transthyretin Amyloidosis (ATTR) With Cardiomyopathy | 3 |
| Baylor Scott and White Heart Hospital | Aortic Valve Disease, Aortic Valve Stenosis, Iliac Disease | 3 |
| Clinical Trial Site | AQP4+ NMOSD, High Cardiovascular Risk, High Risk Cardiovascular Disease | 3 |
| Delricht Research - Plano | Major Depressive Disorder, Depression, Major Depressive Disorder (MDD) | 3 |
| Stryde Research | Focal Epilepsy, SLE, SLE (Systemic Lupus) | 3 |
| Texas Back Institute | Cervical Disc Disease, Chronic Lower Back Pain, Degenerative Disc Disease | 3 |
| ACRC Trials | Non-segmental Vitiligo, Nonsegmental Vitiligo | 2 |
| Baylor Scott & White | Acute Aortic Dissection, Aortic Arch Aneurysm, Aortic Arch Dissection | 2 |
| Baylor Scott & White - The Heart Hospital - Plano | Cardiovascular Diseases, Coronary Artery Disease, In-Stent Restenosis | 2 |
| Baylor Scott & White Medical Center - Plano | Cancer, Cardiovascular Diseases, Heart Diseases | 2 |
| Baylor Scott & White The Heart Hospital | Coronary Artery Disease, High Risk Percutaneous Coronary Intervention, Interventional Cardiology | 2 |
| Baylor Scott & White The Heart Hospital Plano | High-Risk Percutaneous Coronary Intervention, Obstructive Hypertrophic Cardiomyopathy | 2 |
| Baylor Scott & White The Heart Hospital- Plano | Coronary Atherosclerosis Due to Calcified Coronary Lesion, Radiation Protection | 2 |
| Clinical Investigations of Texas | Difficult to Control Hypertension, Psoriatic Arthritis | 2 |
| Medical City Plano | Avascular Necrosis, Dislocation, Hip, Femoral Neck Fractures | 2 |
| Texas Oncology - Plano West | Breast Cancer, Solid Tumours | 2 |
Active & Upcoming Studies in Plano (2026)
Recruiting trials in Plano grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cardiovascular (36 active studies)
- A Prospective, Randomized Multicenter Clinical Trial of the TricValve® Transcatheter Bicaval Valve System in Subjects With Severe Tricuspid Regurgitation. · P+F Products + Features USA Inc.
- ProActive Athlete Heart Program: Proposal for Cardiac Risk Screening in Former High-Intensity Athletes · Baylor Research Institute
Neurology & pain (16 active studies)
- A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine · Phase 3 · Kallyope Inc.
- A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine · Phase 3 · Kallyope Inc.
Cancer & tumors (13 active studies)
- Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer · Phase 3 · Pfizer
- Symbiotic-Lung-04: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Extensive-Stage Small Cell Lung Cancer · Phase 2, Phase 3 · Pfizer
Mental health & behavior (9 active studies)
- A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD) · Phase 2 · Tonix Pharmaceuticals, Inc.
- RE104 Safety and Efficacy Study in Generalized Anxiety Disorder · Phase 2 · Reunion Neuroscience Inc
Diabetes & metabolic (5 active studies)
Eye & vision (5 active studies)
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
- COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME · Phase 3 · EyePoint Pharmaceuticals, Inc.
Common conditions studied in Plano
- Heart Failure (10 active studies)
- Coronary Artery Disease (9 active studies)
- Cardiovascular Diseases (5 active studies)
- Aortic Valve Stenosis (4 active studies)
- Major Depressive Disorder (4 active studies)
- Obesity (4 active studies)
Leading research sponsors in Plano
- Baylor Research Institute
- W.L.Gore & Associates
- AbbVie
- AstraZeneca
- Novartis Pharmaceuticals
Frequently asked questions
How many paid clinical trials are currently recruiting in Plano?
There are approximately 168 recruiting clinical trials in Plano, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Plano pay participants?
Most recruiting trials in Plano compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Plano?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Plano?
The most common conditions under active study in Plano include Heart Failure (10), Coronary Artery Disease (9), Cardiovascular Diseases (5), Aortic Valve Stenosis (4), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Plano?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Plano on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Plano?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Plano?
Recruiting research sites in Plano include The Heart Hospital Baylor Plano, Baylor Scott & White The Heart Hospital - Plano, Aim Trials, LLC, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Plano right now?
The largest active categories in Plano are Cardiovascular (36), Neurology & pain (16), Cancer & tumors (13). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.