Community-Informed Interventions for Equitable Congestive Heart Failure Management in Primary Care
for Congestive Heart Failure
1 location in Rochester
Sponsor: Mayo Clinic
Sex: All·Age: 18+
Code: NCT07730827·Recruiting·Listed Jul 28, 2026
Heart failure Clinical Trials in Rochester, MN
As of August 2026, 20 paid clinical trials are recruiting for Heart failure in Rochester, Minnesota. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Rochester
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
21 clinical trials for Heart failure
·Clear filters· Email me when a new heart failure trial opens in Rochester, MN.
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
for Heart Failure
Drug: Empagliflozin
Sites in Rochester, Saint Paul +84 more locations
Sponsor: Boehringer Ingelheim
Sex: All·Age: 18+
Code: NCT06935370·Phase 3·Recruiting·Listed Apr 2025
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
for Heart Failure
Sites in Rochester, Minneapolis +55 more locations
Sponsor: Abbott Medical Devices
Sex: All·Age: 18+
Code: NCT06526195·Recruiting·Listed Jul 2024
Ultra-High Frequency - Electrocardiogram (UHF-ECG) for the Diagnosis of Ventricular Electrical Dyssynchrony (VED)
for Bradycardia
Sites in Rochester +6 more locations
Sponsor: VDI Technologies
Sex: All·Age: 18+
Code: NCT06641362·Recruiting·Listed Oct 2024
Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II
for Myocardial Infarction
Sites in Rochester +1 more location
Sponsor: AliveCor
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT06271577·Recruiting·Listed Feb 2024
The PeriCut Catheter System Early Feasibility Study (REIMAGINE-HFpEF)
for Heart Failure With Preserved Ejection Fraction
1 location in Rochester
Sponsor: Heart Failure Solutions, Inc.
Sex: All·Age: 30+
Code: NCT06702501·Recruiting·Listed Nov 2024
Voice Analysis for Monitoring Patients With Heart Failure
for Heart Failure
1 location in Rochester
Sponsor: Noah Labs
Sex: All·Age: 18+
Code: NCT06566911·Recruiting·Listed Aug 2024
Exercise Cardiovascular Magnetic Resonance In Heart Failure With Preserved Ejection Fraction
for Heart Failure With Preserved Ejection Fraction
1 location in Rochester
Sponsor: Mayo Clinic
Sex: All·Age: 18 - 80·Accepts healthy volunteers
Code: NCT07401771·Recruiting·Listed Feb 2026
A Study Investigating the Impact of IMT With CR On Exercise Responses In HF
for Heart Failure With Reduced Ejection Fraction
1 location in Rochester
Sponsor: Mayo Clinic
Sex: All·Age: 18+
Code: NCT07086131·Recruiting·Listed Jul 2025
Contrast Echocardiography During Exercise to Assess Pulmonary Blood Volume
for Heart Failure
1 location in Rochester
Sponsor: Mayo Clinic
Sex: All·Age: 18+
Code: NCT06195059·Recruiting·Listed Jan 2024
A Study of 68Ga-Fibroblast Activation Protein Inhibitor (FAPI) Positron Emission Tomography in Heart Failure
for Heart Failure With Preserved Ejection Fraction
1 location in Rochester
Sponsor: Mayo Clinic
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT07083011·Phase 2·Recruiting·Listed Jul 2025
Inspiratory Muscle Training in HFpEF
for Heart Failure
1 location in Rochester
Sponsor: Mayo Clinic
Sex: All·Age: 18+
Code: NCT06510231·Recruiting·Listed Jul 2024
A Study to Evaluate Breathing Muscle Training in Cardiac Rehab
for Healthy
1 location in Rochester
Sponsor: Mayo Clinic
Sex: All·Age: 18+·Accepts healthy volunteers
Code: NCT04984473·Recruiting·Listed Jul 2021
HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets
for Heart Failure
Sites in Rochester +5 more locations
Sponsor: Northwestern University
Sex: All·Age: 30+·Accepts healthy volunteers
Code: NCT05873634·Recruiting·Listed May 2023
Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction
for Heart Failure
Sites in Rochester +5 more locations
Sponsor: Northwestern University
Sex: All·Age: 30+·Accepts healthy volunteers
Code: NCT06517186·Recruiting·Listed Jul 2024
AI-Guided Left Bundle Branch Area Pacing
for Heart Failure
1 location in Rochester
Sponsor: Mayo Clinic
Sex: All·Age: 18+
Code: NCT07206602·Recruiting·Listed Oct 2025
A Study of Paramedic HF Management
for Heart Failure
1 location in Rochester
Sponsor: Mayo Clinic
Sex: All·Age: 18+
Code: NCT06874556·Recruiting·Listed Mar 2025
A Study Of CS Reducer For Symptomatic Heart Failure With HFpEF And CMD
for Heart Failure With Preserved Ejection Fraction
1 location in Rochester
Sponsor: Mayo Clinic
Sex: All·Age: 18+
Code: NCT07093528·Recruiting·Listed Jul 2025
Left vs Left Randomized Clinical Trial
for Heart Failure
Sites in Rochester +56 more locations
Sponsor: Baylor College of Medicine
Sex: All·Age: 18+
Code: NCT05650658·Recruiting·Listed Dec 2022
His Bundle Pacing in Bradycardia and Heart Failure
for Bradycardia
1 location in Rochester
Sponsor: Yong-Mei Cha
Sex: All·Age: 18+
Code: NCT03008291·Recruiting·Listed Jan 2017
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
for Arrhythmia
Sites in Rochester, Minneapolis +82 more locations
Sponsor: Medtronic
Sex: All·Age: All ages
Code: NCT00271180·Recruiting·Listed Dec 2005
Top Research Study Locations in Rochester
Researchers run research studies in Rochester, MN at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Mayo Clinic | Heart Failure, Breast Cancer, Ovarian Cancer | 463 |
| Mayo Clinic in Rochester | Malignant Solid Neoplasm, Hematopoietic and Lymphatic System Neoplasm, Breast Carcinoma | 393 |
| Mayo Clinic Rochester | CRC, Chronic Lymphocytic Leukemia, Colorectal Cancer | 79 |
| Mayo Clinic - Rochester | Endometrial Cancer, Epilepsy, Epilepsy (Treatment Refractory) | 30 |
| Mayo Clinic Minnesota | Healthy, Advanced Melanoma, Aging | 27 |
| Mayo Clinic in Rochester, Minnesota | Breast Neoplasms, Multiple Myeloma, Neoplasm Metastasis | 13 |
| Mayo Clinic, Rochester | Interstitial Lung Diseases, Acute Kidney Failure, Acute Kidney Insufficiency | 10 |
| Mayo Clinic Cancer Center | Lung Cancer, PDAC, PDAC - Pancreatic Ductal Adenocarcinoma | 7 |
| Clinical Trial Site | Advanced Hepatocellular Carcinoma, End Stage Renal Disease, Hereditary Transthyretin-Mediated Amyloidosis With Polyneuropathy | 5 |
| Mayo Clinic (Data Collection Only) | Adult T-cell Leukemia/Lymphoma, Aggressive NK-cell Leukemia, Anaplastic Large Cell Lymphoma, ALK-Positive | 4 |
| Mayo Clinic Cancer Center Outpatient Pharmacy | Colorectal Neoplasms, Advanced Renal Cell Carcinoma, Advanced or Metastatic Renal Cell Carcinoma | 4 |
| Mayo Clinic in Minnesota | Advanced Solid Tumor, Colorectal Cancer (CRC), Cutaneous Melanoma | 4 |
| GSK Investigational Site | Amyloidosis, Gastrointestinal Neoplasms, Neoplasms, Prostate | 3 |
| Mayo Clinic - PPDS | Alpha1-Antitrypsin Deficiency, Metastatic HER2-positive Breast Cancer, Uveal Melanoma | 3 |
| Mayo Clinic Comprehensive Cancer Center | Acute Myeloid Leukemia, Advanced Or Metastatic Merkel Cell Carcinoma, Clear Cell Renal Cell Carcinoma (ccRCC) | 3 |
| Mayo Clinic Hospital | ADA SCID, Glioblastoma, Glioblastoma (GBM) | 3 |
| Mayo Clinic- Rochester | Aneurysmal Subarachnoid Hemorrhage (aSAH), Cerebral Vasospasm, Crohns Disease | 3 |
| 89bio Clinical Study Site | Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis | 2 |
| Crinetics Study Site | Classic Congenital Adrenal Hyperplasia, Congenital Adrenal Hyperplasia, Neuroendocrine Neoplasm | 2 |
| Mayo Clinic - PIN | Crohn's Disease (CD), Obesity, Overweight | 2 |
| Mayo Clinic - Rochester Minnesota | Intermediate Risk Non-Muscle Invasive Bladder Cancer, Low-grade Upper Tract Urothelial Carcinoma | 2 |
| Mayo Clinic Children's - PIN | Developmental and Epileptic Encephalopathy, Dravet Syndrome | 2 |
| Mayo Clinic Department of Ophthalmology | Amblyopia | 2 |
| Mayo Clinic Foundation | Orthostatic Hypotension, Reflex Syncope, Weight Loss | 2 |
| Mayo Clinic Hospital, Methodist Campus, Research Pharmacy | Advanced Renal Cell Carcinoma, Advanced or Metastatic Renal Cell Carcinoma, Carcinoma, Renal Cell | 2 |
Active & Upcoming Studies in Rochester (2026)
Recruiting trials in Rochester grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (368 active studies)
Cardiovascular (94 active studies)
Neurology & pain (69 active studies)
- The Effect of Dry Needling With Electrical Stimulation on Individuals With Restless Legs Syndrome · Mayo Clinic
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
Diabetes & metabolic (32 active studies)
- Upper Body Subcutaneous Exosome Release in Response to a Meal in Obesity · Mayo Clinic
- Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes · Insulet Corporation
Mental health & behavior (13 active studies)
Pediatric (7 active studies)
- Predicting the Need for Prolonged Respiratory Support in Neonates Delivered in a Lower-Level NICU Setting · Mayo Clinic
- Supraglottic Airway for Resuscitation Trial · Children's Hospital of Philadelphia
Vaccines (6 active studies)
Eye & vision (4 active studies)
- 24-hour Effect of Rocklatan Compared With Latanoprost in Open Angle Glaucoma and Ocular Hypertension Patients · Phase 4 · Mayo Clinic
- Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD) · Phase 3 · AbbVie
HIV / STI (2 active studies)
- Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States · Phase 2 · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Analytic Treatment Interruption (ATI) to Assess HIV Cure · Mayo Clinic
Common conditions studied in Rochester
- Malignant Solid Neoplasm (19 active studies)
- Heart Failure (16 active studies)
- Multiple Myeloma (15 active studies)
- Ovarian Cancer (15 active studies)
- Breast Cancer (14 active studies)
- Healthy (14 active studies)
Leading research sponsors in Rochester
- Mayo Clinic
- AstraZeneca
- National Cancer Institute (NCI)
- Eli Lilly and Company
- Children's Oncology Group
Frequently asked questions
How many paid clinical trials are currently recruiting in Rochester?
There are approximately 1,208 recruiting clinical trials in Rochester, Minnesota listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Rochester pay participants?
Most recruiting trials in Rochester compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Rochester?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Rochester?
The most common conditions under active study in Rochester include Malignant Solid Neoplasm (19), Heart Failure (16), Multiple Myeloma (15), Ovarian Cancer (15), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Rochester?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Rochester on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Rochester?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Rochester?
Recruiting research sites in Rochester include Mayo Clinic, Mayo Clinic in Rochester, Mayo Clinic Rochester, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Rochester right now?
The largest active categories in Rochester are Cancer & tumors (368), Cardiovascular (94), Neurology & pain (69). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
Browse more clinical trials
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