Solid tumor Clinical Trials in Rochester, MN
As of August 2026, 48 paid clinical trials are recruiting for Solid tumor in Rochester, Minnesota. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Related specialties in Rochester
Filter results
48 clinical trials for Solid tumor
·Clear filters·FOG-001 in Locally Advanced or Metastatic Solid Tumors
Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion
A Solid Tumor Study for Long Term Treatment of Cancer Patients Who Participated in Adagrasib Studies
A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations
A Study of 177Lu-FAP-2286 in Advanced Solid Tumors
Study of Lunresertib Alone or in Combination With RP-3500 or Debio 0123 in Patients With Advanced Solid Tumors
First in Human Study of TUB-030 in Patients With Advanced Solid Tumors
A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers
A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss
A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors
Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration
A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid Tumors
First in Human Study of TORL-1-23 in Participants With Advanced Cancer
JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration
Study of IBI3020 Treatment in Participants With Late-Stage Solid Tumors
A Phase 1, First in Human Study of TORL-4-500 in Patients With Advanced Cancer
A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)
Ambient Sensing Room to Detect Early Signs of Adverse Events in Hospitalized Patients With Cancer
Impact of Physician Behavior on Cancer Distress
A Mindfulness-Based Stress Reduction Program for Improving Mental Health Outcomes for Underserved Cancer Patients in Minnesota
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
Project: Every Child for Younger Patients With Cancer
Voices: Messages of Wisdom and Hope in the Face of Illness
Validation of DNA Methylation Markers for Universal and Site-specific Guided Cancer Detection, VANGUARD Study
Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors
Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Platinum Resistant Ovarian Cancer
Assessing Effect of Spinal Cord Stimulation on Pain and Quality of Life With Chemotherapy-Induced Peripheral Neuropathy
Evaluation of a Novel Auto Segmentation Algorithm for Normal Structure Delineation in Radiation Treatment Planning
Evaluation of Anti-PD-1 Therapy by Monitoring T Cell Responses in Melanoma, Lung and Other Cancer Types
Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases
Examining Blood and Tissue Samples to Identify Diagnostic Markers in Patients With Metastatic Cancer Undergoing Tumor Removal
Group Cognitive Behavior Sessions (CBCSM) to Decrease Distress in Cancer Patients
Acupressure for the Reduction of Anxiety in Patients Receiving Cancer-Directed Therapy
Wisconsin Ginseng for Decreasing Cancer Related Fatigue
Virtual Art Therapy Assisted Re-Integration to Improve Biopsychosocial Outcomes in Adolescent and Young Adult Cancer Survivors, AVATARS Trial
SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial
Top Research Study Locations in Rochester
Researchers run research studies in Rochester, MN at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Mayo Clinic | Heart Failure, Breast Cancer, Ovarian Cancer | 463 |
| Mayo Clinic in Rochester | Malignant Solid Neoplasm, Hematopoietic and Lymphatic System Neoplasm, Breast Carcinoma | 393 |
| Mayo Clinic Rochester | CRC, Chronic Lymphocytic Leukemia, Colorectal Cancer | 79 |
| Mayo Clinic - Rochester | Endometrial Cancer, Epilepsy, Epilepsy (Treatment Refractory) | 30 |
| Mayo Clinic Minnesota | Healthy, Advanced Melanoma, Aging | 27 |
| Mayo Clinic in Rochester, Minnesota | Breast Neoplasms, Multiple Myeloma, Neoplasm Metastasis | 13 |
| Mayo Clinic, Rochester | Interstitial Lung Diseases, Acute Kidney Failure, Acute Kidney Insufficiency | 10 |
| Mayo Clinic Cancer Center | Lung Cancer, PDAC, PDAC - Pancreatic Ductal Adenocarcinoma | 7 |
| Clinical Trial Site | Advanced Hepatocellular Carcinoma, End Stage Renal Disease, Hereditary Transthyretin-Mediated Amyloidosis With Polyneuropathy | 5 |
| Mayo Clinic (Data Collection Only) | Adult T-cell Leukemia/Lymphoma, Aggressive NK-cell Leukemia, Anaplastic Large Cell Lymphoma, ALK-Positive | 4 |
| Mayo Clinic Cancer Center Outpatient Pharmacy | Colorectal Neoplasms, Advanced Renal Cell Carcinoma, Advanced or Metastatic Renal Cell Carcinoma | 4 |
| Mayo Clinic in Minnesota | Advanced Solid Tumor, Colorectal Cancer (CRC), Cutaneous Melanoma | 4 |
| GSK Investigational Site | Amyloidosis, Gastrointestinal Neoplasms, Neoplasms, Prostate | 3 |
| Mayo Clinic - PPDS | Alpha1-Antitrypsin Deficiency, Metastatic HER2-positive Breast Cancer, Uveal Melanoma | 3 |
| Mayo Clinic Comprehensive Cancer Center | Acute Myeloid Leukemia, Advanced Or Metastatic Merkel Cell Carcinoma, Clear Cell Renal Cell Carcinoma (ccRCC) | 3 |
| Mayo Clinic Hospital | ADA SCID, Glioblastoma, Glioblastoma (GBM) | 3 |
| Mayo Clinic- Rochester | Aneurysmal Subarachnoid Hemorrhage (aSAH), Cerebral Vasospasm, Crohns Disease | 3 |
| 89bio Clinical Study Site | Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis | 2 |
| Crinetics Study Site | Classic Congenital Adrenal Hyperplasia, Congenital Adrenal Hyperplasia, Neuroendocrine Neoplasm | 2 |
| Mayo Clinic - PIN | Crohn's Disease (CD), Obesity, Overweight | 2 |
| Mayo Clinic - Rochester Minnesota | Intermediate Risk Non-Muscle Invasive Bladder Cancer, Low-grade Upper Tract Urothelial Carcinoma | 2 |
| Mayo Clinic Children's - PIN | Developmental and Epileptic Encephalopathy, Dravet Syndrome | 2 |
| Mayo Clinic Department of Ophthalmology | Amblyopia | 2 |
| Mayo Clinic Foundation | Orthostatic Hypotension, Reflex Syncope, Weight Loss | 2 |
| Mayo Clinic Hospital, Methodist Campus, Research Pharmacy | Advanced Renal Cell Carcinoma, Advanced or Metastatic Renal Cell Carcinoma, Carcinoma, Renal Cell | 2 |
Active & Upcoming Studies in Rochester (2026)
Recruiting trials in Rochester grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (368 active studies)
Cardiovascular (94 active studies)
Neurology & pain (69 active studies)
- The Effect of Dry Needling With Electrical Stimulation on Individuals With Restless Legs Syndrome · Mayo Clinic
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
Diabetes & metabolic (32 active studies)
- Upper Body Subcutaneous Exosome Release in Response to a Meal in Obesity · Mayo Clinic
- Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes · Insulet Corporation
Mental health & behavior (13 active studies)
Pediatric (7 active studies)
- Predicting the Need for Prolonged Respiratory Support in Neonates Delivered in a Lower-Level NICU Setting · Mayo Clinic
- Supraglottic Airway for Resuscitation Trial · Children's Hospital of Philadelphia
Vaccines (6 active studies)
Eye & vision (4 active studies)
- 24-hour Effect of Rocklatan Compared With Latanoprost in Open Angle Glaucoma and Ocular Hypertension Patients · Phase 4 · Mayo Clinic
- Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD) · Phase 3 · AbbVie
HIV / STI (2 active studies)
- Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States · Phase 2 · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Analytic Treatment Interruption (ATI) to Assess HIV Cure · Mayo Clinic
Common conditions studied in Rochester
- Malignant Solid Neoplasm (19 active studies)
- Heart Failure (16 active studies)
- Multiple Myeloma (15 active studies)
- Ovarian Cancer (15 active studies)
- Breast Cancer (14 active studies)
- Healthy (14 active studies)
Leading research sponsors in Rochester
- Mayo Clinic
- AstraZeneca
- National Cancer Institute (NCI)
- Eli Lilly and Company
- Children's Oncology Group
Frequently asked questions
How many paid clinical trials are currently recruiting in Rochester?
There are approximately 1,208 recruiting clinical trials in Rochester, Minnesota listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Rochester pay participants?
Most recruiting trials in Rochester compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Rochester?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Rochester?
The most common conditions under active study in Rochester include Malignant Solid Neoplasm (19), Heart Failure (16), Multiple Myeloma (15), Ovarian Cancer (15), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Rochester?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Rochester on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Rochester?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Rochester?
Recruiting research sites in Rochester include Mayo Clinic, Mayo Clinic in Rochester, Mayo Clinic Rochester, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Rochester right now?
The largest active categories in Rochester are Cancer & tumors (368), Cardiovascular (94), Neurology & pain (69). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.