As of July 2026, 1,203 paid clinical trials are recruiting in Rochester, Minnesota. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Rochester offers studies at sites including Mayo Clinic for conditions such as Malignant Solid Neoplasm, Breast Cancer, Heart Failure, Ovarian Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Researchers run research studies in Rochester, MN at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Mayo Clinic | Heart Failure, Breast Cancer, Cardiovascular Diseases | 454 |
| Mayo Clinic in Rochester | Malignant Solid Neoplasm, Hematopoietic and Lymphatic System Neoplasm, Breast Carcinoma | 404 |
| Mayo Clinic Rochester | CRC, Chronic Lymphocytic Leukemia, Colorectal Cancer | 73 |
| Mayo Clinic - Rochester | Endometrial Cancer, Epilepsy, Epilepsy (Treatment Refractory) | 31 |
| Mayo Clinic Minnesota | Healthy, Advanced Melanoma, Aging | 28 |
| Mayo Clinic in Rochester, Minnesota | Multiple Myeloma, Neoplasm Metastasis, Amyloid | 13 |
| Mayo Clinic, Rochester | Interstitial Lung Diseases, Acute Kidney Failure, Acute Kidney Insufficiency | 11 |
| Mayo Clinic Cancer Center | Lung Cancer, PDAC, PDAC - Pancreatic Ductal Adenocarcinoma | 7 |
| Mayo Clinic in Minnesota | Advanced Solid Tumor, Bladder Spasms, Colorectal Cancer (CRC) | 6 |
| Clinical Trial Site | Advanced Hepatocellular Carcinoma, End Stage Renal Disease, Hereditary Transthyretin-Mediated Amyloidosis With Polyneuropathy | 5 |
| Mayo Clinic (Data Collection Only) | Adult T-cell Leukemia/Lymphoma, Aggressive NK-cell Leukemia, Anaplastic Large Cell Lymphoma, ALK-Positive | 4 |
| Mayo Clinic - PIN | Crohn's Disease (CD), Developmental and Epileptic Encephalopathy, Dravet Syndrome | 4 |
| Mayo Clinic - PPDS | Alpha1-Antitrypsin Deficiency, Metastatic HER2-positive Breast Cancer, Short Bowel Syndrome (SBS) | 4 |
| GSK Investigational Site | Amyloidosis, Gastrointestinal Neoplasms, Neoplasms, Prostate | 3 |
| Mayo Clinic Cancer Center Outpatient Pharmacy | Advanced Renal Cell Carcinoma, Advanced or Metastatic Renal Cell Carcinoma, Cachexia | 3 |
| Mayo Clinic Comprehensive Cancer Center | Acute Myeloid Leukemia, Advanced Or Metastatic Merkel Cell Carcinoma, Clear Cell Renal Cell Carcinoma (ccRCC) | 3 |
| Mayo Clinic Hospital | ADA SCID, Glioblastoma, Glioblastoma (GBM) | 3 |
| Mayo Clinic- Minnesota | Chronic Lymphocytic Leukemia, Non-Hodgkin Lymphoma, Adenocarcinoma | 3 |
| Mayo Clinic- Rochester | Aneurysmal Subarachnoid Hemorrhage (aSAH), Cerebral Vasospasm, Crohns Disease | 3 |
| 89bio Clinical Study Site | Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis | 2 |
| Crinetics Study Site | Classic Congenital Adrenal Hyperplasia, Congenital Adrenal Hyperplasia, Neuroendocrine Neoplasm | 2 |
| Mayo Clinic - Rochester Minnesota | Intermediate Risk Non-Muscle Invasive Bladder Cancer, Low-grade Upper Tract Urothelial Carcinoma | 2 |
| Mayo Clinic Department of Ophthalmology | Amblyopia | 2 |
| Mayo Clinic Foundation | Orthostatic Hypotension, Reflex Syncope, Weight Loss | 2 |
| Mayo Clinic Saint Marys Campus | Intracerebral Hemorrhage, Stroke, Stroke, Acute | 2 |
Recruiting trials in Rochester grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
There are approximately 1,203 recruiting clinical trials in Rochester, Minnesota listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Rochester compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Rochester include Malignant Solid Neoplasm (20), Breast Cancer (15), Heart Failure (15), Ovarian Cancer (15), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Rochester on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Rochester include Mayo Clinic, Mayo Clinic in Rochester, Mayo Clinic Rochester, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Rochester are Cancer & tumors (366), Cardiovascular (90), Neurology & pain (71). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.